Conditional deletion of NF-κB-Inducing kinase (NIK) in adult mice disrupts mature B cell survival and activation

Journal of Immunology

Volumn 195, Issue 3, 2015, Pages 953-964

  Brightbill, Hans D ^a   Jackman, Janet K ^a   Suto, Eric ^a   Kennedy, Heather ^a   Jones, Charles ^a   Chalasani, Sreedevi ^a   Lin, Zhonghua ^a   Tam, Lucinda ^a   Roose Girma, Meron ^a   Balazs, Mercedesz ^a,b   Austin, Cary D ^a   Lee, Wyne P ^a   Wu, Lawren C ^a,b  

^a GENENTECH INC   (United States)

^b AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN M; NF KAPPA B INDUCING KINASE; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG; B CELL ACTIVATING FACTOR; CHUK PROTEIN, MOUSE; I KAPPA B KINASE; NF-KAPPA B KINASE; PROTEIN SERINE THREONINE KINASE; TAMOXIFEN; TNFSF13B PROTEIN, MOUSE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; CELL SURVIVAL; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; ENZYME INACTIVATION; GERMINAL CENTER; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN PRODUCTION; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE COUNT; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; ANIMAL; BIOSYNTHESIS; BLOOD; CELL DIFFERENTIATION; CYTOLOGY; GENE DELETION; GENETICS; GERMLINE MUTATION; IMMUNOLOGY; KNOCKOUT MOUSE; LYMPH NODE; LYMPHOCYTE ACTIVATION; METABOLISM; SIGNAL TRANSDUCTION; SPLEEN;

ANIMALS; B-CELL ACTIVATING FACTOR; B-LYMPHOCYTES; CELL DIFFERENTIATION; CELL SURVIVAL; GERM-LINE MUTATION; I-KAPPA B KINASE; IMMUNOGLOBULIN A; LYMPH NODES; LYMPHOCYTE ACTIVATION; MICE; MICE, KNOCKOUT; NF-KAPPA B P52 SUBUNIT; PROTEIN-SERINE-THREONINE KINASES; SEQUENCE DELETION; SIGNAL TRANSDUCTION; SPLEEN; TAMOXIFEN;

EID: 84937688539     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1401514     Document Type: Article

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