Chemical synthesis of erythropoietin glycoforms for insights into the relationship between glycosylation pattern and bioactivity

Science Advances

Volumn 2, Issue 1, 2016, Pages

  Murakami, Masumi ^a   Kiuchi, Tatsuto ^a   Nishihara, Mika ^b   Tezuka, Katsunari ^b   Okamoto, Ryo ^a   Izumi, Masayuki ^a   Kajihara, Yasuhiro ^a  

^a OSAKA UNIVERSITY   (Japan)

^b Present address GlyTech Inc   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSYLATION; PEPTIDES; SYNTHESIS (CHEMICAL);

ERYTHROPOIETIN (EPO); GLYCOFORMS; GLYCOPEPTIDES; HOMOGENEOUS FORMS; IN-VIVO; NATIVE CHEMICAL LIGATION; SYNTHETIC STRATEGIES;

BIOACTIVITY;

ERYTHROPOIETIN; GLYCOPEPTIDE; OLIGOSACCHARIDE; SIALOOLIGOSACCHARIDES;

AMINO ACID SEQUENCE; ANIMAL; BAGG ALBINO MOUSE; CELL LINE; GLYCOSYLATION; HUMAN; MOUSE; SYNTHESIS;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; ERYTHROPOIETIN; GLYCOPEPTIDES; GLYCOSYLATION; HUMANS; MICE; MICE, INBRED BALB C; OLIGOSACCHARIDES;

EID: 84982794311     PISSN: None     EISSN: 23752548     Source Type: Journal    
DOI: 10.1126/sciadv.1500678     Document Type: Article

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