Chemical synthesis of an erythropoietin glycoform containing a complex-type disialyloligosaccharide

Angewandte Chemie - International Edition

Volumn 51, Issue 15, 2012, Pages 3567-3572

  Murakami, Masumi ^a   Okamoto, Ryo ^a   Izumi, Masayuki ^a   Kajihara, Yasuhiro ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

glycoproteins; peptides; sialic acids; solid phase synthesis

Indexed keywords

ACID-LABILE; AMINO ACID RESIDUES; CHEMICAL SYNTHESIS; ERYTHROPOIETIN (EPO); GLYCOFORMS; REACTION CONDITIONS; SIALIC ACIDS; SOLID PHASE PEPTIDE SYNTHESIS; SOLID PHASE SYNTHESIS; THIOESTERS;

AMINO ACIDS; CARBOXYLIC ACIDS; GLYCOPROTEINS; SYNTHESIS (CHEMICAL);

PEPTIDES;

DRUG DERIVATIVE; ERYTHROPOIETIN; ISOPROTEIN; OLIGOSACCHARIDE; SIALOOLIGOSACCHARIDES;

AMINO ACID SEQUENCE; ARTICLE; CARBOHYDRATE ANALYSIS; CATALYSIS; CHEMISTRY; GLYCOSYLATION; MOLECULAR GENETICS; SYNTHESIS;

AMINO ACID SEQUENCE; CARBOHYDRATE SEQUENCE; CATALYSIS; ERYTHROPOIETIN; GLYCOSYLATION; MOLECULAR SEQUENCE ANNOTATION; OLIGOSACCHARIDES; PROTEIN ISOFORMS;

EID: 84859524073     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201109034     Document Type: Article

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