Chemical synthesis of intentionally misfolded homogeneous glycoprotein: A unique approach for the study of glycoprotein quality control

Journal of the American Chemical Society

Volumn 134, Issue 17, 2012, Pages 7238-7241

  Izumi, Masayuki ^a,b   Makimura, Yutaka ^a,b   Dedola, Simone ^a,b   Seko, Akira ^b   Kanamori, Akiko ^b,c   Sakono, Masafumi ^b,c   Ito, Yukishige ^b,c   Kajihara, Yasuhiro ^a,b  

^a OSAKA UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c RIKEN   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL SYNTHESIS; CHEMICAL TOOLS; ENDOPLASMIC RETICULUM; FOLDING INTERMEDIATES; GLUCOSYLTRANSFERASES; GLYCOPEPTIDES; HYDROPHOBIC NATURE; MISFOLDING; UDP-GLUCOSE;

BIOCHEMISTRY; CELL MEMBRANES; CONTROL SYSTEMS; GLUCOSE; QUALITY ASSURANCE; QUALITY CONTROL;

GLYCOPROTEINS;

GLUCOSYLTRANSFERASE; GLYCOPEPTIDE; GLYCOPROTEIN; MANNOSE; OLIGOSACCHARIDE; UDP GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE; UNCLASSIFIED DRUG;

ARTICLE; ENDOPLASMIC RETICULUM; GLYCOPROTEIN SYNTHESIS; HYDROPHOBICITY; OXIDATION; PEPTIDE SYNTHESIS; PROTEIN FOLDING; QUALITY CONTROL;

AMINO ACID SEQUENCE; ENDOPLASMIC RETICULUM; GLUCOSYLTRANSFERASES; GLYCOPEPTIDES; GLYCOPROTEINS; HUMANS; MANNOSE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OLIGOSACCHARIDES; OXIDATION-REDUCTION; PROTEIN FOLDING; SUBSTRATE SPECIFICITY;

EID: 84860802199     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja3013177     Document Type: Article

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