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Volumn 116, Issue 2, 2016, Pages 379-393

Hepatic lipase inactivation decreases atherosclerosis in insulin resistance by reducing LIGHT/lymphotoxin β-receptor pathway

Author keywords

Atherosclerosis; Hepatic lipase; Inflammation; Insulin resistance; Macrophage

Indexed keywords

APOLIPOPROTEIN E; CD69 ANTIGEN; HERPESVIRUS ENTRY MEDIATOR LIGAND; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INTERLEUKIN 6; LIVER TRIACYLGLYCEROL LIPASE; LYMPHOTOXIN BETA RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; INSULIN RECEPTOR SUBSTRATE; IRS2 PROTEIN, MOUSE; LIPC PROTEIN, MOUSE; LTBR PROTEIN, HUMAN; LTBR PROTEIN, MOUSE; MESSENGER RNA; TNFSF14 PROTEIN, HUMAN; TNFSF14 PROTEIN, MOUSE; TRIACYLGLYCEROL LIPASE;

EID: 84982734929     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH15-10-0773     Document Type: Article
Times cited : (12)

References (51)
  • 1
    • 33846422032 scopus 로고    scopus 로고
    • Obesity and diabetes in the developing world--a growing challenge
    • Hossain P, Kawar B, El Nahas M. Obesity and diabetes in the developing world--a growing challenge. N Engl J Med 2007; 356: 213-215.
    • (2007) N Engl J Med , vol.356 , pp. 213-215
    • Hossain, P.1    Kawar, B.2    El Nahas, M.3
  • 2
    • 59749096514 scopus 로고    scopus 로고
    • Managing diabetic dyslipidaemia: Beyond statin therapy
    • Neeli H, Gadi R, Rader DJ. Managing diabetic dyslipidaemia: beyond statin therapy. Curr Diab Rep 2009; 9: 11-17.
    • (2009) Curr Diab Rep , vol.9 , pp. 11-17
    • Neeli, H.1    Gadi, R.2    Rader, D.J.3
  • 3
    • 70350245011 scopus 로고    scopus 로고
    • National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity
    • Alberti KG, Eckel RH, Grundy SM, et al. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidaemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation 2009; 120: 1640-1645.
    • (2009) Circulation , vol.120 , pp. 1640-1645
    • Alberti, K.G.1    Eckel, R.H.2    Grundy, S.M.3
  • 4
    • 2442600044 scopus 로고    scopus 로고
    • The G-250A promoter polymorphism of the hepatic lipase gene predicts the conversion from impaired glucose tolerance to type 2 diabetes mellitus: The Finnish Diabetes Prevention Study
    • Todorova B, Kubaszek A, Pihlajamaki J, et al. The G-250A promoter polymorphism of the hepatic lipase gene predicts the conversion from impaired glucose tolerance to type 2 diabetes mellitus: the Finnish Diabetes Prevention Study. J Clin Endocrinol Metab 2004; 89: 2019-2023.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 2019-2023
    • Todorova, B.1    Kubaszek, A.2    Pihlajamaki, J.3
  • 5
    • 84875407187 scopus 로고    scopus 로고
    • Interaction between cholesteryl ester transfer protein and hepatic lipase encoding genes and the risk of type 2 diabetes: Results from the Telde study
    • Lopez-Rios L, Novoa FJ, Chirino R, et al. Interaction between cholesteryl ester transfer protein and hepatic lipase encoding genes and the risk of type 2 diabetes: results from the Telde study. PLoS One 2011; 6: e27208.
    • (2011) Plos One , vol.6
    • Lopez-Rios, L.1    Novoa, F.J.2    Chirino, R.3
  • 6
    • 13244279651 scopus 로고    scopus 로고
    • The G-250A substitution in the promoter region of the hepatic lipase gene is associated with the conversion from impaired glucose tolerance to type 2 diabetes: The STOP-NIDDM trial
    • Zacharova J, Todorova BR, Chiasson JL, et al. The G-250A substitution in the promoter region of the hepatic lipase gene is associated with the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial. J Intern Med 2005; 257: 185-193.
    • (2005) J Intern Med , vol.257 , pp. 185-193
    • Zacharova, J.1    Todorova, B.R.2    Chiasson, J.L.3
  • 7
    • 33744928073 scopus 로고    scopus 로고
    • Genetic variation in the hepatic lipase gene and the risk of coronary heart disease among US diabetic men: Potential interaction with obesity
    • Zhang C, Lopez-Ridaura R, Rimm EB, et al. Genetic variation in the hepatic lipase gene and the risk of coronary heart disease among US diabetic men: potential interaction with obesity. Diabetologia 2006; 49: 1552-1559.
    • (2006) Diabetologia , vol.49 , pp. 1552-1559
    • Zhang, C.1    Lopez-Ridaura, R.2    Rimm, E.B.3
  • 8
    • 8544272562 scopus 로고    scopus 로고
    • The ligand-binding function of hepatic lipase modulates the development of atherosclerosis in transgenic mice
    • Gonzalez-Navarro H, Nong Z, Amar MJ, et al. The ligand-binding function of hepatic lipase modulates the development of atherosclerosis in transgenic mice. J Biol Chem 2004; 279: 45312-45321.
    • (2004) J Biol Chem , vol.279 , pp. 45312-45321
    • Gonzalez-Navarro, H.1    Nong, Z.2    Amar, M.J.3
  • 10
    • 84857635930 scopus 로고    scopus 로고
    • The effect of hepatic lipase on coronary artery disease in humans is influenced by the underlying lipoprotein phenotype
    • Brunzell JD, Zambon A, Deeb SS. The effect of hepatic lipase on coronary artery disease in humans is influenced by the underlying lipoprotein phenotype. Bio-chim Biophys Acta 2011; 1821: 365-372.
    • (2011) Bio-Chim Biophys Acta , vol.1821 , pp. 365-372
    • Brunzell, J.D.1    Zambon, A.2    Deeb, S.S.3
  • 11
    • 21344435253 scopus 로고    scopus 로고
    • Hepatic lipase gene variant -514C>T is associated with lipoprotein and insulin sensitivity response to regular exercise: The HERITAGE Family Study
    • Teran-Garcia M, Santoro N, Rankinen T, et al. Hepatic lipase gene variant -514C>T is associated with lipoprotein and insulin sensitivity response to regular exercise: the HERITAGE Family Study. Diabetes 2005; 54: 2251-2255.
    • (2005) Diabetes , vol.54 , pp. 2251-2255
    • Teran-Garcia, M.1    Santoro, N.2    Rankinen, T.3
  • 12
    • 2942683422 scopus 로고    scopus 로고
    • Abdominal obesity and dyslipidaemia in the metabolic syndrome: Importance of type 2 diabetes and familial combined hyperlipidaemia in coronary artery disease risk
    • Carr MC, Brunzell JD. Abdominal obesity and dyslipidaemia in the metabolic syndrome: importance of type 2 diabetes and familial combined hyperlipidaemia in coronary artery disease risk. J Clin Endocrinol Metab 2004; 89: 2601-2607.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 2601-2607
    • Carr, M.C.1    Brunzell, J.D.2
  • 13
    • 0032438117 scopus 로고    scopus 로고
    • Lamellar lipoproteins uniquely contribute to hyperlipidaemia in mice doubly deficient in apolipoprotein
    • Bergeron N, Kotite L, Verges M, et al. Lamellar lipoproteins uniquely contribute to hyperlipidaemia in mice doubly deficient in apolipoprotein E and hepatic li-pase. Proc Natl Acad Sci USA 1998; 95: 15647-15652.
    • (1998) E and Hepatic Li-Pase. Proc Natl Acad Sci USA , vol.95 , pp. 15647-15652
    • Bergeron, N.1    Kotite, L.2    Verges, M.3
  • 14
    • 70349425845 scopus 로고    scopus 로고
    • Small dense LDL and VLDL predict common carotid artery IMT and elicit an inflammatory response in peripheral blood mononuclear and endothelial cells
    • Norata GD, Raselli S, Grigore L, et al. Small dense LDL and VLDL predict common carotid artery IMT and elicit an inflammatory response in peripheral blood mononuclear and endothelial cells. Atherosclerosis 2009; 206: 556-562.
    • (2009) Atherosclerosis , vol.206 , pp. 556-562
    • Norata, G.D.1    Raselli, S.2    Grigore, L.3
  • 15
    • 84921964053 scopus 로고    scopus 로고
    • IL-17 and Th17 cells in atherosclerosis: Subtle and contextual roles
    • Taleb S, Tedgui A, Mallat Z. IL-17 and Th17 cells in atherosclerosis: subtle and contextual roles. Arterioscler Thromb Vasc Biol 2015; 35: 258-264.
    • (2015) Arterioscler Thromb Vasc Biol , vol.35 , pp. 258-264
    • Taleb, S.1    Tedgui, A.2    Mallat, Z.3
  • 16
    • 84866318436 scopus 로고    scopus 로고
    • Macrophage proliferation and apoptosis in atherosclerosis
    • Andres V, Pello OM, Silvestre-Roig C. Macrophage proliferation and apoptosis in atherosclerosis. Curr Opin Lipidol 2012; 23: 429-438.
    • (2012) Curr Opin Lipidol , vol.23 , pp. 429-438
    • Andres, V.1    Pello, O.M.2    Silvestre-Roig, C.3
  • 17
    • 0141514575 scopus 로고    scopus 로고
    • Towards understanding acute destabilization of vulnerable atherosclerotic plaques
    • Dickson BC, Gotlieb AI. Towards understanding acute destabilization of vulnerable atherosclerotic plaques. Cardiovasc Pathol 2003; 12: 237-248.
    • (2003) Cardiovasc Pathol , vol.12 , pp. 237-248
    • Dickson, B.C.1    Gotlieb, A.I.2
  • 18
    • 74049093243 scopus 로고    scopus 로고
    • The impact of macrophage insulin resistance on advanced atherosclerotic plaque progression
    • Tabas I, Tall A, Accili D. The impact of macrophage insulin resistance on advanced atherosclerotic plaque progression. Circ Res 2010; 106: 58-67.
    • (2010) Circ Res , vol.106 , pp. 58-67
    • Tabas, I.1    Tall, A.2    Accili, D.3
  • 19
    • 79958715229 scopus 로고    scopus 로고
    • Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation
    • Jenkins SJ, Ruckerl D, Cook PC, et al. Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation. Science 2011; 332: 1284-1288.
    • (2011) Science , vol.332 , pp. 1284-1288
    • Jenkins, S.J.1    Ruckerl, D.2    Cook, P.C.3
  • 20
    • 84904365676 scopus 로고    scopus 로고
    • Insulin resistance aggravates atherosclerosis by reducing vascular smooth muscle cell survival and increasing CX3CL1/CX3CR1 axis
    • Martinez-Hervas S, Vinue A, Nunez L, et al. Insulin resistance aggravates atherosclerosis by reducing vascular smooth muscle cell survival and increasing CX3CL1/CX3CR1 axis. Cardiovasc Res 2014; 103: 324-336.
    • (2014) Cardiovasc Res , vol.103 , pp. 324-336
    • Martinez-Hervas, S.1    Vinue, A.2    Nunez, L.3
  • 21
    • 71549121695 scopus 로고    scopus 로고
    • Treating inflammation in atherosclerotic cardiovascular disease: Emerging therapies
    • Klingenberg R, Hansson GK. Treating inflammation in atherosclerotic cardiovascular disease: emerging therapies. Eur Heart J 2009; 30: 2838-2844.
    • (2009) Eur Heart J , vol.30 , pp. 2838-2844
    • Klingenberg, R.1    Hansson, G.K.2
  • 23
    • 0036249830 scopus 로고    scopus 로고
    • Identification of mouse and human macrophages as a site of synthesis of hepatic lipase
    • Gonzalez-Navarro H, Nong Z, Freeman L, et al. Identification of mouse and human macrophages as a site of synthesis of hepatic lipase. J Lipid Res 2002; 43: 671-675.
    • (2002) J Lipid Res , vol.43 , pp. 671-675
    • Gonzalez-Navarro, H.1    Nong, Z.2    Freeman, L.3
  • 24
    • 67649781177 scopus 로고    scopus 로고
    • Leukocyte-derived hepatic lipase increases HDL and decreases en face aortic atherosclerosis in LDLr-/- mice expressing CETP
    • Hime NJ, Black AS, Bulgrien JJ, et al. Leukocyte-derived hepatic lipase increases HDL and decreases en face aortic atherosclerosis in LDLr-/- mice expressing CETP. J Lipid Res 2008; 49: 2113-2123.
    • (2008) J Lipid Res , vol.49 , pp. 2113-2123
    • Hime, N.J.1    Black, A.S.2    Bulgrien, J.J.3
  • 25
    • 0041385950 scopus 로고    scopus 로고
    • Hepatic lipase expression in mac-rophages contributes to atherosclerosis in apoE-deficient and LCAT-transgenic mice
    • Nong Z, Gonzalez-Navarro H, Amar M, et al. Hepatic lipase expression in mac-rophages contributes to atherosclerosis in apoE-deficient and LCAT-transgenic mice. J Clin Invest 2003; 112: 367-378.
    • (2003) J Clin Invest , vol.112 , pp. 367-378
    • Nong, Z.1    Gonzalez-Navarro, H.2    Amar, M.3
  • 26
    • 84873437974 scopus 로고    scopus 로고
    • Hepatic lipase- and endothelial lipase-deficiency in mice promotes macrophage-to-feces RCT and HDL antioxidant properties
    • Escola-Gil JC, Chen X, Julve J, et al. Hepatic lipase- and endothelial lipase-deficiency in mice promotes macrophage-to-feces RCT and HDL antioxidant properties. Biochim Biophys Acta 2013; 1831: 691-697.
    • (2013) Biochim Biophys Acta , vol.1831 , pp. 691-697
    • Escola-Gil, J.C.1    Chen, X.2    Julve, J.3
  • 27
    • 84874597449 scopus 로고    scopus 로고
    • Depletion of FOXP3+ regulatory T cells promotes hypercholesterolaemia and atherosclerosis
    • Klingenberg R, Gerdes N, Badeau RM, et al. Depletion of FOXP3+ regulatory T cells promotes hypercholesterolaemia and atherosclerosis. J Clin Invest 2013; 123: 1323-1334.
    • (2013) J Clin Invest , vol.123 , pp. 1323-1334
    • Klingenberg, R.1    Gerdes, N.2    Badeau, R.M.3
  • 28
    • 34247371874 scopus 로고    scopus 로고
    • Lymphotoxin beta receptor-dependent control of lipid homeostasis
    • Lo JC, Wang Y, Tumanov AV, et al. Lymphotoxin beta receptor-dependent control of lipid homeostasis. Science 2007; 316: 285-288.
    • (2007) Science , vol.316 , pp. 285-288
    • Lo, J.C.1    Wang, Y.2    Tumanov, A.V.3
  • 29
    • 36048950184 scopus 로고    scopus 로고
    • Plasma insulin levels predict the development of atherosclerosis when IRS2 deficiency is combined with severe hypercholesterolaemia in apolipoprotein E-null mice
    • Gonzalez-Navarro HV-C, M. Pastor, M-F. Vinue, A. White, M. F. Burks, DA, V. Plasma insulin levels predict the development of atherosclerosis when IRS2 deficiency is combined with severe hypercholesterolaemia in apolipoprotein E-null mice. Frontiers in Bioscience 2007; 12: 2291-2298.
    • (2007) Frontiers in Bioscience , vol.12 , pp. 2291-2298
    • Gonzalez-Navarro, H.V.-C.1    Pastor, M.2    Vinue, M.-F.3    White, A.4    Burks, M.F.5
  • 30
    • 57549092036 scopus 로고    scopus 로고
    • Molecular mechanisms of atherosclerosis in metabolic syndrome: Role of reduced IRS2-dependent signaling
    • Gonzalez-Navarro H, Vinue A, Vila-Caballer M, et al. Molecular mechanisms of atherosclerosis in metabolic syndrome: role of reduced IRS2-dependent signaling. Arterioscler Thromb Vasc Biol 2008; 28: 2187-2194.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 2187-2194
    • Gonzalez-Navarro, H.1    Vinue, A.2    Vila-Caballer, M.3
  • 31
    • 77951888636 scopus 로고    scopus 로고
    • P19(ARF) deficiency reduces macrophage and vascular smooth muscle cell apoptosis and aggravates atherosclerosis
    • Gonzalez-Navarro H, Abu Nabah YN, Vinue A, et al. p19(ARF) deficiency reduces macrophage and vascular smooth muscle cell apoptosis and aggravates atherosclerosis. J Am Coll Cardiol 2010; 55: 2258-2268.
    • (2010) J am Coll Cardiol , vol.55 , pp. 2258-2268
    • Gonzalez-Navarro, H.1    Abu Nabah, Y.N.2    Vinue, A.3
  • 32
    • 84872793355 scopus 로고    scopus 로고
    • LIGHT/TNFSR14 can regulate hepatic lipase expression by hepatocytes independent of T cells and Kupffer cells
    • Chellan B, Koroleva EP, Sontag TJ, et al. LIGHT/TNFSR14 can regulate hepatic lipase expression by hepatocytes independent of T cells and Kupffer cells. PLoS One 2013; 8: e54719.
    • (2013) Plos One , vol.8
    • Chellan, B.1    Koroleva, E.P.2    Sontag, T.J.3
  • 33
    • 84879109173 scopus 로고    scopus 로고
    • Insulin sensitivity and carotid intima-media thickness: Relationship between insulin sensitivity and cardiovascular risk study
    • Kozakova M, Natali A, Dekker J, et al. Insulin sensitivity and carotid intima-media thickness: relationship between insulin sensitivity and cardiovascular risk study. Arterioscler Thromb Vasc Biol 2013; 33: 1409-1417.
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 1409-1417
    • Kozakova, M.1    Natali, A.2    Dekker, J.3
  • 34
    • 84867404418 scopus 로고    scopus 로고
    • CD14++CD16+ monocytes independently predict cardiovascular events: A cohort study of 951 patients referred for elective coronary angiography
    • Rogacev KS, Cremers B, Zawada AM, et al. CD14++CD16+ monocytes independently predict cardiovascular events: a cohort study of 951 patients referred for elective coronary angiography. J Am Coll Cardiol 2012; 60: 1512-1520.
    • (2012) J am Coll Cardiol , vol.60 , pp. 1512-1520
    • Rogacev, K.S.1    Cremers, B.2    Zawada, A.M.3
  • 35
    • 0035576394 scopus 로고    scopus 로고
    • Constitutive expression of LIGHT on T cells leads to lymphocyte activation, inflammation, and tissue destruction
    • Shaikh RB, Santee S, Granger SW, et al. Constitutive expression of LIGHT on T cells leads to lymphocyte activation, inflammation, and tissue destruction. J Immunol 2001; 167: 6330-6337.
    • (2001) J Immunol , vol.167 , pp. 6330-6337
    • Shaikh, R.B.1    Santee, S.2    Granger, S.W.3
  • 36
    • 7044269440 scopus 로고    scopus 로고
    • Hepatic lipase mRNA, protein, and plasma enzyme activity is increased in the insulin-resistant, fructose-fed Syrian golden hamster and is partially normalized by the insulin sensitizer rosiglita-zone
    • Lewis GF, Murdoch S, Uffelman K, et al. Hepatic lipase mRNA, protein, and plasma enzyme activity is increased in the insulin-resistant, fructose-fed Syrian golden hamster and is partially normalized by the insulin sensitizer rosiglita-zone. Diabetes 2004; 53: 2893-2900.
    • (2004) Diabetes , vol.53 , pp. 2893-2900
    • Lewis, G.F.1    Murdoch, S.2    Uffelman, K.3
  • 37
    • 79952808680 scopus 로고    scopus 로고
    • Physical activity modifies the effect of LPL, LIPC, and CETP polymorphisms on HDL-C levels and the risk of myocardial infarction in women of European ancestry
    • Ahmad T, Chasman DI, Buring JE, et al. Physical activity modifies the effect of LPL, LIPC, and CETP polymorphisms on HDL-C levels and the risk of myocardial infarction in women of European ancestry. Circ Cardiovasc Genet 2011; 4: 74-80.
    • (2011) Circ Cardiovasc Genet , vol.4 , pp. 74-80
    • Ahmad, T.1    Chasman, D.I.2    Buring, J.E.3
  • 38
    • 84942115958 scopus 로고    scopus 로고
    • Metformin and Inflammation: Its Potential Beyond Glucose-lowering Effect
    • Saisho Y. Metformin and Inflammation: Its Potential Beyond Glucose-lowering Effect. Endocr Metab Immune Disord Drug Targets 2015; 15: 196-205.
    • (2015) Endocr Metab Immune Disord Drug Targets , vol.15 , pp. 196-205
    • Saisho, Y.1
  • 39
    • 84926330020 scopus 로고    scopus 로고
    • Combined sub-optimal doses of rosuvastatin and bexarotene impair angiotensin II-induced arterial mononuclear cell adhesion through inhibition of Nox5 signaling pathways and increased RXR/PPARalpha and RXR/PPARgamma interactions
    • Escudero P, Martinez de Maranon A, Collado A, et al. Combined sub-optimal doses of rosuvastatin and bexarotene impair angiotensin II-induced arterial mononuclear cell adhesion through inhibition of Nox5 signaling pathways and increased RXR/PPARalpha and RXR/PPARgamma interactions. Antioxid Redox Signal 2015; 22: 901-920.
    • (2015) Antioxid Redox Signal , vol.22 , pp. 901-920
    • Escudero, P.1    Martinez De Maranon, A.2    Collado, A.3
  • 40
    • 80455128548 scopus 로고    scopus 로고
    • Insulin resistance, hyperglycemia, and atherosclerosis
    • Bornfeldt KE, Tabas I. Insulin resistance, hyperglycemia, and atherosclerosis. Cell Metab 2011; 14: 575-585.
    • (2011) Cell Metab , vol.14 , pp. 575-585
    • Bornfeldt, K.E.1    Tabas, I.2
  • 41
    • 79955535643 scopus 로고    scopus 로고
    • Macrophages in the pathogenesis of atherosclerosis
    • Moore KJ, Tabas I. Macrophages in the pathogenesis of atherosclerosis. Cell 2011; 145: 341-355.
    • (2011) Cell , vol.145 , pp. 341-355
    • Moore, K.J.1    Tabas, I.2
  • 42
    • 85027928970 scopus 로고    scopus 로고
    • The tumor necrosis factor family member LIGHT is a target for asthmatic airway remodeling
    • Doherty TA, Soroosh P, Khorram N, et al. The tumor necrosis factor family member LIGHT is a target for asthmatic airway remodeling. Nat Med 2011; 17: 596-603.
    • (2011) Nat Med , vol.17 , pp. 596-603
    • Doherty, T.A.1    Soroosh, P.2    Khorram, N.3
  • 43
    • 33845970192 scopus 로고    scopus 로고
    • Ly-6Chi monocytes dominate hypercholes-terolaemia-associated monocytosis and give rise to macrophages in atheromata
    • Swirski FK, Libby P, Aikawa E, et al. Ly-6Chi monocytes dominate hypercholes-terolaemia-associated monocytosis and give rise to macrophages in atheromata. J Clin Invest 2007; 117: 195-205.
    • (2007) J Clin Invest , vol.117 , pp. 195-205
    • Swirski, F.K.1    Libby, P.2    Aikawa, E.3
  • 44
    • 80053241162 scopus 로고    scopus 로고
    • A glimpse on the phenomenon of mac-rophage polarization during atherosclerosis
    • Pello OM, Silvestre C, De Pizzol M, et al. A glimpse on the phenomenon of mac-rophage polarization during atherosclerosis. Immunobiology 2011; 216: 1172-1176.
    • (2011) Immunobiology , vol.216 , pp. 1172-1176
    • Pello, O.M.1    Silvestre, C.2    De Pizzol, M.3
  • 45
    • 26944483097 scopus 로고    scopus 로고
    • Enhanced plasma levels of LIGHT in unstable angina: Possible pathogenic role in foam cell formation and thrombosis
    • Scholz H, Sandberg W, Damas JK, et al. Enhanced plasma levels of LIGHT in unstable angina: possible pathogenic role in foam cell formation and thrombosis. Circulation 2005; 112: 2121-2129.
    • (2005) Circulation , vol.112 , pp. 2121-2129
    • Scholz, H.1    Sandberg, W.2    Damas, J.K.3
  • 46
    • 77957723199 scopus 로고    scopus 로고
    • Circulating lymphotoxin beta receptor and atherosclerosis: Observations from the Dallas Heart Study
    • Owens AW, Matulevicius S, Rohatgi A, et al. Circulating lymphotoxin beta receptor and atherosclerosis: observations from the Dallas Heart Study. Atherosclerosis 2010; 212: 601-606.
    • (2010) Atherosclerosis , vol.212 , pp. 601-606
    • Owens, A.W.1    Matulevicius, S.2    Rohatgi, A.3
  • 47
    • 84929443400 scopus 로고    scopus 로고
    • Deficiency in lymphotoxin beta receptor protects from atherosclerosis in apoE-deficient mice
    • Grandoch M, Feldmann K, Gothert JR, et al. Deficiency in lymphotoxin beta receptor protects from atherosclerosis in apoE-deficient mice. Circ Res 2015; 116: e57-68.
    • (2015) Circ Res , vol.116 , pp. e57-e68
    • Grandoch, M.1    Feldmann, K.2    Gothert, J.R.3
  • 48
    • 84937573919 scopus 로고    scopus 로고
    • Artery Tertiary Lymphoid Organs Control Aorta Immunity and Protect against Atherosclerosis via Vascular Smooth Muscle Cell Lymphotoxin beta Receptors
    • Hu D, Mohanta SK, Yin C, et al. Artery Tertiary Lymphoid Organs Control Aorta Immunity and Protect against Atherosclerosis via Vascular Smooth Muscle Cell Lymphotoxin beta Receptors. Immunity 2015; 42: 1100-1115.
    • (2015) Immunity , vol.42 , pp. 1100-1115
    • Hu, D.1    Mohanta, S.K.2    Yin, C.3
  • 49
    • 33750507694 scopus 로고    scopus 로고
    • Signaling pathways of LIGHT induced macro-phage migration and vascular smooth muscle cell proliferation
    • Wei CY, Chou YH, Ho FM, et al. Signaling pathways of LIGHT induced macro-phage migration and vascular smooth muscle cell proliferation. J Cell Physiol 2006; 209: 735-743.
    • (2006) J Cell Physiol , vol.209 , pp. 735-743
    • Wei, C.Y.1    Chou, Y.H.2    Ho, F.M.3
  • 50
    • 84929571913 scopus 로고    scopus 로고
    • Roles of p38alpha mitogen-activated protein kinase in mouse models of inflammatory diseases and cancer
    • Gupta J, Nebreda AR. Roles of p38alpha mitogen-activated protein kinase in mouse models of inflammatory diseases and cancer. Febs J 2015; 282: 1841-1857.
    • (2015) Febs J , vol.282 , pp. 1841-1857
    • Gupta, J.1    Nebreda, A.R.2
  • 51
    • 84925880935 scopus 로고    scopus 로고
    • Anti-inflammatory therapies for atherosclerosis
    • Back M, Hansson GK. Anti-inflammatory therapies for atherosclerosis. Nat Rev Cardiol 2015; 12: 199-211.
    • (2015) Nat Rev Cardiol , vol.12 , pp. 199-211
    • Back, M.1    Hansson, G.K.2


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