Hepatic lipase- and endothelial lipase-deficiency in mice promotes macrophage-to-feces RCT and HDL antioxidant properties

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1831, Issue 4, 2013, Pages 691-697

  Escolà Gil, Joan Carles ^a,b   Chen, Xiangyu ^a,c   Julve, Josep ^a,b   Quesada, Helena ^a   Santos, David ^b   Metso, Jari ^d   Tous, Monica ^a   Jauhiainen, Matti ^d   Blanco Vaca, Francisco ^a,b,c  

^a BIOMEDICAL RESEARCH INSTITUTE SANT PAU IIB SANT PAU   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^d NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

apoA I; Endothelial lipase; HDL; Hepatic lipase; Oxidation; Reverse cholesterol transport

Indexed keywords

ENDOTHELIAL LIPASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIVER TRIACYLGLYCEROL LIPASE; LOW DENSITY LIPOPROTEIN; PHOSPHOLIPID; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ENZYME DEFICIENCY; ENZYME METABOLISM; FEMALE; IN VIVO STUDY; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; WILD TYPE;

ANIMALS; APOLIPOPROTEIN A-I; BIOLOGICAL TRANSPORT; CHOLESTEROL; CHOLESTEROL, HDL; FECES; LIPASE; LIPOPROTEINS, HDL; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; OXIDATION-REDUCTION;

MUS;

EID: 84873437974     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2013.01.003     Document Type: Article

References (38)

1. D.J. Rader Molecular regulation of HDL metabolism and function: implications for novel therapies J. Clin. Invest. 116 2006 3090 3100
2. G. Olivecrona, and T. Olivecrona Triglyceride lipases and atherosclerosis Curr. Opin. Lipidol. 21 2010 409 415
3. T. Yasuda, T. Ishida, and D.J. Rader Update on the role of endothelial lipase in high-density lipoprotein metabolism, reverse cholesterol transport, and atherosclerosis Circ. J. 74 2010 2263 2270
4. C. Chatterjee, and D.L. Sparks Hepatic lipase, high density lipoproteins, and hypertriglyceridemia Am. J. Pathol. 178 2011 1429 1433
5. W. Annema, and U.J. Tietge Role of hepatic lipase and endothelial lipase in high-density lipoprotein-mediated reverse cholesterol transport Curr. Atheroscler. Rep. 13 2011 257 265
6. H. Mezdour, R. Jones, C. Dengremont, G. Castro, and N. Maeda Hepatic lipase deficiency increases plasma cholesterol but reduces susceptibility to atherosclerosis in apolipoprotein E-deficient mice J. Biol. Chem. 272 1997 13570 13575
7. G. Lambert, M.J. Amar, P. Martin, J. Fruchart-Najib, B. Foger, R.D. Shamburek, H.B. Brewer Jr., and S. Santamarina-Fojo Hepatic lipase deficiency decreases the selective uptake of HDL-cholesteryl esters in vivo J. Lipid Res. 41 2000 667 672
8. T. Ishida, S. Choi, R.K. Kundu, K. Hirata, E.M. Rubin, A.D. Cooper, and T. Quertermous Endothelial lipase is a major determinant of HDL level J. Clin. Invest. 111 2003 347 355
9. K. Ma, M. Cilingiroglu, J.D. Otvos, C.M. Ballantyne, A.J. Marian, and L. Chan Endothelial lipase is a major genetic determinant for high-density lipoprotein concentration, structure, and metabolism Proc. Natl. Acad. Sci. U. S. A. 100 2003 2748 2753
10. G.E. Homanics, H.V. de Silva, J. Osada, S.H. Zhang, H. Wong, J. Borensztajn, and N. Maeda Mild dyslipidemia in mice following targeted inactivation of the hepatic lipase gene J. Biol. Chem. 270 1995 2974 2980
11. I.L. Ruel, P. Couture, J.S. Cohn, A. Bensadoun, M. Marcil, and B. Lamarche Evidence that hepatic lipase deficiency in humans is not associated with proatherogenic changes in HDL composition and metabolism J. Lipid Res. 45 2004 1528 1537
12. S.J. Busch, R.L. Barnhart, G.A. Martin, M.C. Fitzgerald, M.T. Yates, S.J. Mao, C.E. Thomas, and R.L. Jackson Human hepatic triglyceride lipase expression reduces high density lipoprotein and aortic cholesterol in cholesterol-fed transgenic mice J. Biol. Chem. 269 1994 16376 16382
13. H.L. Dichek, W. Brecht, J. Fan, Z.S. Ji, S.P. McCormick, H. Akeefe, L. Conzo, D.A. Sanan, K.H. Weisgraber, S.G. Young, J.M. Taylor, and R.W. Mahley Overexpression of hepatic lipase in transgenic mice decreases apolipoprotein B-containing and high density lipoproteins. Evidence that hepatic lipase acts as a ligand for lipoprotein uptake J. Biol. Chem. 273 1998 1896 1903
14. M. Jaye, K.J. Lynch, J. Krawiec, D. Marchadier, C. Maugeais, K. Doan, V. South, D. Amin, M. Perrone, and D.J. Rader A novel endothelial-derived lipase that modulates HDL metabolism Nat. Genet. 21 1999 424 428
15. A. Zambon, S.S. Deeb, J.E. Hokanson, B.G. Brown, and J.D. Brunzell Common variants in the promoter of the hepatic lipase gene are associated with lower levels of hepatic lipase activity, buoyant LDL, and higher HDL2 cholesterol Arterioscler. Thromb. Vasc. Biol. 18 1998 1723 1729
16. A.C. Edmondson, R.J. Brown, S. Kathiresan, L.A. Cupples, S. Demissie, A.K. Manning, M.K. Jensen, E.B. Rimm, J. Wang, A. Rodrigues, V. Bamba, S.A. Khetarpal, M.L. Wolfe, S. Derohannessian, M. Li, M.P. Reilly, J. Aberle, D. Evans, R.A. Hegele, and D.J. Rader Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans J. Clin. Invest. 119 2009 1042 1050
17. R.J. Brown, A.C. Edmondson, N. Griffon, T.B. Hill, I.V. Fuki, K.O. Badellino, M. Li, M.L. Wolfe, M.P. Reilly, and D.J. Rader A naturally occurring variant of endothelial lipase associated with elevated HDL exhibits impaired synthesis J. Lipid Res. 50 2009 1910 1916
18. W. Jin, X. Wang, J.S. Millar, T. Quertermous, G.H. Rothblat, J.M. Glick, and D.J. Rader Hepatic proprotein convertases modulate HDL metabolism Cell Metab. 6 2007 129 136
19. R.J. Brown, W.R. Lagor, S. Sankaranaravanan, T. Yasuda, T. Quertermous, G.H. Rothblat, and D.J. Rader Impact of combined deficiency of hepatic lipase and endothelial lipase on the metabolism of both high-density lipoproteins and apolipoprotein B-containing lipoproteins Circ. Res. 107 2010 357 364
20. T. Hara, T. Ishida, Y. Kojima, H. Tanaka, T. Yasuda, M. Shinohara, R. Toh, and K. Hirata Targeted deletion of endothelial lipase increases HDL particles with anti-inflammatory properties both in vitro and in vivo J. Lipid Res. 52 2011 57 67
21. S.L. Karackattu, B. Trigatti, and M. Krieger Hepatic lipase deficiency delays atherosclerosis, myocardial infarction, and cardiac dysfunction and extends lifespan in SR-BI/apolipoprotein E double knockout mice Arterioscler. Thromb. Vasc. Biol. 26 2006 548 554
22. D. Barcat, A. Amadio, A. Palos-Pinto, D. Daret, P. Benlian, M. Darmon, and A.M. Berard Combined hyperlipidemia/hyperalphalipoproteinemia associated with premature spontaneous atherosclerosis in mice lacking hepatic lipase and low density lipoprotein receptor Atherosclerosis 188 2005 347 355
23. T. Ishida, S.Y. Choi, R.K. Kundu, J. Spin, T. Yamashita, K. Hirata, Y. Kojima, M. Yokoyama, A.D. Cooper, and T. Quertermous Endothelial lipase modulates susceptibility to atherosclerosis in apolipoprotein-E-deficient mice J. Biol. Chem. 279 2004 45085 45092
24. K.W. Ko, A. Paul, K. Ma, L. Li, and L. Chan Endothelial lipase modulates HDL but has no effect on atherosclerosis development in apoE -/- and LDLR -/- mice J Lipid Res 46 2005 2586 2594
25. N.R. Council Guide for the Care and Use of Laboratory Animals, Vol.NIH Publication 85-23 (rev.), Washington, DC 1996
26. J. Julve, J.C. Escola-Gil, N. Rotllan, C. Fievet, E. Vallez, C. de la Torre, V. Ribas, J.H. Sloan, and F. Blanco-Vaca Human apolipoprotein A-II determines plasma triglycerides by regulating lipoprotein lipase activity and high-density lipoprotein proteome Arterioscler. Thromb. Vasc. Biol. 30 2010 232 238
27. J.C. Escola-Gil, G. Llaverias, J. Julve, M. Jauhiainen, J. Mendez-Gonzalez, and F. Blanco-Vaca The cholesterol content of Western diets plays a major role in the paradoxical increase in high-density lipoprotein cholesterol and upregulates the macrophage reverse cholesterol transport pathway Arterioscler. Thromb. Vasc. Biol. 31 2011 2493 2499
28. R. van Haperen, A. van Tol, P. Vermeulen, M. Jauhiainen, T. van Gent, P. van den Berg, S. Ehnholm, F. Grosveld, A. van der Kamp, and R. de Crom Human plasma phospholipid transfer protein increases the antiatherogenic potential of high density lipoproteins in transgenic mice Arterioscler. Thromb. Vasc. Biol. 20 2000 1082 1088
29. A. Marzal-Casacuberta, F. Blanco-Vaca, B.Y. Ishida, J. Julve-Gil, J. Shen, S. Calvet-Marquez, F. Gonzalez-Sastre, and L. Chan Functional lecithin:cholesterol acyltransferase deficiency and high density lipoprotein deficiency in transgenic mice overexpressing human apolipoprotein A-II J. Biol. Chem. 271 1996 6720 6728
30. M. Jauhiainen, J. Metso, R. Pahlman, S. Blomqvist, A. van Tol, and C. Ehnholm Human plasma phospholipid transfer protein causes high density lipoprotein conversion J. Biol. Chem. 268 1993 4032 4036
31. V. Ribas, J.L. Sanchez-Quesada, R. Anton, M. Camacho, J. Julve, J.C. Escola-Gil, L. Vila, J. Ordonez-Llanos, and F. Blanco-Vaca Human apolipoprotein A-II enrichment displaces paraoxonase from HDL and impairs its antioxidant properties: a new mechanism linking HDL protein composition and antiatherogenic potential Circ. Res. 95 2004 789 797
32. N. Rotllan, G. Llaverias, J. Julve, M. Jauhiainen, L. Calpe-Berdiel, C. Hernandez, R. Simo, F. Blanco-Vaca, and J.C. Escola-Gil Differential effects of gemfibrozil and fenofibrate on reverse cholesterol transport from macrophages to feces in vivo Biochim. Biophys. Acta 1811 2011 104 110
33. Y. Zhang, I. Zanotti, M.P. Reilly, J.M. Glick, G.H. Rothblat, and D.J. Rader Overexpression of apolipoprotein A-I promotes reverse transport of cholesterol from macrophages to feces in vivo Circulation 108 2003 661 663
34. M. Navab, S.Y. Hama, C.J. Cooke, G.M. Anantharamaiah, M. Chaddha, L. Jin, G. Subbanagounder, K.F. Faull, S.T. Reddy, N.E. Miller, and A.M. Fogelman Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: step 1 J Lipid Res 41 2000 1481 1494
35. Z. Nong, H. Gonzalez-Navarro, M. Amar, L. Freeman, C. Knapper, E.B. Neufeld, B.J. Paigen, R.F. Hoyt, J. Fruchart-Najib, and S. Santamarina-Fojo Hepatic lipase expression in macrophages contributes to atherosclerosis in apoE-deficient and LCAT-transgenic mice J. Clin. Invest. 112 2003 367 378
36. T. Yasuda, K. Hirata, T. Ishida, Y. Kojima, H. Tanaka, T. Okada, T. Quertermous, and M. Yokoyama Endothelial lipase is increased by inflammation and promotes LDL uptake in macrophages J. Atheroscler. Thromb. 14 2007 192 201
37. Y. Kojma, K. Hirata, T. Ishida, Y. Shimokawa, N. Inoue, S. Kawashima, T. Quertermous, and M. Yokoyama Endothelial lipase modulates monocyte adhesion to the vessel wall. A potential role in inflammation J. Biol. Chem. 279 2004 54032 54038
38. J.C. Lo, Y. Wang, A.V. Tumanov, M. Bamji, Z. Yao, C.A. Reardon, G.S. Getz, and Y.X. Fu Lymphotoxin beta receptor-dependent control of lipid homeostasis Science 316 2007 285 288