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Volumn 6, Issue , 2016, Pages

Metabolic role of dipeptidyl peptidase 4 (DPP4) in primary human (pre)adipocytes

Author keywords

[No Author keywords available]

Indexed keywords

2 CHLORO 5 NITRO N (4 PYRIDYL)BENZAMIDE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; BENZAMIDE DERIVATIVE; DIPEPTIDYL PEPTIDASE IV; FABP4 PROTEIN, HUMAN; FATTY ACID BINDING PROTEIN; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PIOGLITAZONE; PPARGC1A PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; PYRIDINE DERIVATIVE; PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING) KINASE; SMALL INTERFERING RNA; TRANSCRIPTOME;

EID: 84982082392     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep23074     Document Type: Article
Times cited : (60)

References (40)
  • 1
    • 79959466293 scopus 로고    scopus 로고
    • Diabetes mellitus: New drugs for a new epidemic
    • Nicholson, G., & Hall, G. M. Diabetes mellitus: New drugs for a new epidemic. Br J Anaesth. 107, 65-73 (2011
    • (2011) Br J Anaesth , vol.107 , pp. 65-73
    • Nicholson, G.1    Hall, G.M.2
  • 2
    • 78649686908 scopus 로고    scopus 로고
    • Dipeptidyl peptidase-4 inhibitors in the treatment of type 2 diabetes: A comparative review
    • Deacon, C. F. Dipeptidyl peptidase-4 inhibitors in the treatment of type 2 diabetes: A comparative review. Diabetes, Obes. Metab. 13, 7-18 (2011
    • (2011) Diabetes, Obes. Metab , vol.13 , pp. 7-18
    • Deacon, C.F.1
  • 3
    • 33846006173 scopus 로고    scopus 로고
    • The incretin system: Glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
    • Drucker, D. J., & Nauck, M. The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes. Lancet 368, 1696-705 (2006
    • (2006) Lancet , vol.368 , pp. 1696-1705
    • Drucker, D.J.1    Nauck, M.2
  • 4
    • 34249902025 scopus 로고    scopus 로고
    • Dipeptidyl peptidase-4 inhibition and the treatment of type 2 diabetes
    • Drucker, D. J. Dipeptidyl Peptidase-4 Inhibition and the Treatment of Type 2 Diabetes. Diabetes Care 30, 1335-1343 (2007
    • (2007) Diabetes Care , vol.30 , pp. 1335-1343
    • Drucker, D.J.1
  • 5
    • 0034612348 scopus 로고    scopus 로고
    • Enhanced insulin secretion and improved glucose tolerance in mice lacking CD26
    • Marguet D., et al. Enhanced insulin secretion and improved glucose tolerance in mice lacking CD26. Proc. Natl. Acad. Sci. USA 97, 6874-6979 (2000
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 6874-6979
    • Marguet, D.1
  • 6
    • 0037974604 scopus 로고    scopus 로고
    • Mice lacking dipeptidyl peptidase IV are protected against obesity and insulin resistance
    • Conarello S. L., et al. Mice lacking dipeptidyl peptidase IV are protected against obesity and insulin resistance. Proc. Natl. Acad. Sci. USA 100, 6825-6830 (2003
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 6825-6830
    • Conarello, S.L.1
  • 7
    • 84860390325 scopus 로고    scopus 로고
    • Incretin effect: GLP-1, GIP, DPP4
    • Kazafeos, K. Incretin effect: GLP-1, GIP, DPP4. Diabetes Res. Clin. Pract. 93 (SUPPL. 1), S32-S36 (2011
    • (2011) Diabetes Res. Clin. Pract , vol.93 , pp. S32-S36
    • Kazafeos, K.1
  • 8
    • 0037787851 scopus 로고    scopus 로고
    • Dipeptidyl-peptidase IV from bench to bedside: An update on structural properties, functions, and clinical aspects of the enzyme DPP IV
    • Lambeir, A. M., Durinx, C., Scharpe, S., & De Meester, I. Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions, and clinical aspects of the enzyme DPP IV. Crit. Rev. Clin. Lab. Sci. 40, 209-294 (2003
    • (2003) Crit. Rev. Clin. Lab. Sci , vol.40 , pp. 209-294
    • Lambeir, A.M.1    Durinx, C.2    Scharpe, S.3    De Meester, I.4
  • 9
    • 70350328161 scopus 로고    scopus 로고
    • Dipeptidyl peptidase inhibitors, an emerging drug class for inflammatory disease?
    • Yazbeck, R., Howarth, G. S., & Abbott, C. Dipeptidyl peptidase inhibitors, an emerging drug class for inflammatory disease? Trends Pharmacol. Sci. 30, 600-607 (2009
    • (2009) Trends Pharmacol. Sci , vol.30 , pp. 600-607
    • Yazbeck, R.1    Howarth, G.S.2    Abbott, C.3
  • 10
    • 17144404555 scopus 로고    scopus 로고
    • Dipeptidyl peptidase IV and related enzymes in cell biology and liver disorders
    • Gorrell, M. D. Dipeptidyl peptidase IV and related enzymes in cell biology and liver disorders. Clin. Sci. (Lond) 108, 277-292 (2005
    • (2005) Clin. Sci. (Lond , vol.108 , pp. 277-292
    • Gorrell, M.D.1
  • 11
    • 84897109133 scopus 로고    scopus 로고
    • Dipeptidyl peptidase-4 inhibitor attenuates hepatic fibrosis via suppression of activated hepatic stellate cell in rats
    • Kaji K., et al. Dipeptidyl peptidase-4 inhibitor attenuates hepatic fibrosis via suppression of activated hepatic stellate cell in rats. J. Gastroenterol. 49, 481-491 (2014
    • (2014) J. Gastroenterol , vol.49 , pp. 481-491
    • Kaji, K.1
  • 12
    • 0035723325 scopus 로고    scopus 로고
    • CD26: A multifunctional integral membrane and secreted protein of activated lymphocytes
    • Gorrell, M. D., Gysbers, V., & McCaughan, G. W. CD26: A multifunctional integral membrane and secreted protein of activated lymphocytes. Scand. J. Immunol. 54, 249-264 (2001
    • (2001) Scand. J. Immunol , vol.54 , pp. 249-264
    • Gorrell, M.D.1    Gysbers, V.2    McCaughan, G.W.3
  • 13
    • 84860204551 scopus 로고    scopus 로고
    • Cardiovascular biology of the incretin system
    • Ussher, J. R., & Drucker, D. J. Cardiovascular biology of the incretin system. Endocr. Rev. 33, 187-215 (2012
    • (2012) Endocr. Rev , vol.33 , pp. 187-215
    • Ussher, J.R.1    Drucker, D.J.2
  • 14
    • 84872041568 scopus 로고    scopus 로고
    • Apintu potential role for dendritic cell/macrophage-expressing DPP4 in obesity-induced visceral inflammation
    • Zhong J., et al. Apintu potential role for dendritic cell/macrophage-expressing DPP4 in obesity-induced visceral inflammation. Diabetes 62, 149-157 (2013
    • (2013) Diabetes , vol.62 , pp. 149-157
    • Zhong, J.1
  • 15
    • 84872424922 scopus 로고    scopus 로고
    • An emerging role of dipeptidyl peptidase 4 (DPP4) beyond glucose control: Potential implications in cardiovascular disease
    • Zhong, J., Rao, X., & Rajagopalan, S. An emerging role of dipeptidyl peptidase 4 (DPP4) beyond glucose control: Potential implications in cardiovascular disease. Atherosclerosis 226, 305-314 (2013
    • (2013) Atherosclerosis , vol.226 , pp. 305-314
    • Zhong, J.1    Rao, X.2    Rajagopalan, S.3
  • 16
    • 43949154623 scopus 로고
    • CD26: A surface protease involved in T-cell activation
    • Fleischer, B. CD26: A surface protease involved in T-cell activation. Immunol. Today 15, 180-184 (1994
    • (1994) Immunol. Today , vol.15 , pp. 180-184
    • Fleischer, B.1
  • 17
    • 84891888112 scopus 로고    scopus 로고
    • Adipose dipeptidyl peptidase-4 and obesity: Correlation with insulin resistance and depot-specific release from adipose tissue in vivo and in vitro
    • Sell H., et al. Adipose dipeptidyl peptidase-4 and obesity: Correlation with insulin resistance and depot-specific release from adipose tissue in vivo and in vitro. Diabetes Care 36, 4083-4090 (2013
    • (2013) Diabetes Care , vol.36 , pp. 4083-4090
    • Sell, H.1
  • 18
    • 80052096595 scopus 로고    scopus 로고
    • Dipeptidyl peptidase 4 is a novel adipokine potentially linking obesity to the metabolic syndrome
    • Lamers D., et al. Dipeptidyl peptidase 4 is a novel adipokine potentially linking obesity to the metabolic syndrome. Diabetes 60, 1917-1925 (2011
    • (2011) Diabetes , vol.60 , pp. 1917-1925
    • Lamers, D.1
  • 19
    • 84874406712 scopus 로고    scopus 로고
    • The role of adipokines in β -cell failure of type 2 diabetes
    • Dunmore, S. J., & Brown, J. E. The role of adipokines in β -cell failure of type 2 diabetes. J. Endocrinol. 216, T37-T45 (2013
    • (2013) J. Endocrinol , vol.216 , pp. T37-T45
    • Dunmore, S.J.1    Brown, J.E.2
  • 20
    • 33747356154 scopus 로고    scopus 로고
    • Adipose tissue: From lipid storage compartment to endocrine organ
    • Scherer, P. E. Adipose tissue: From lipid storage compartment to endocrine organ. Diabetes 55, 1537-1545 (2006
    • (2006) Diabetes , vol.55 , pp. 1537-1545
    • Scherer, P.E.1
  • 21
    • 84896053103 scopus 로고    scopus 로고
    • Adipose tissue and its role in organ crosstalk
    • Romacho, T., Elsen, M., Rohrborn, D., & Eckel, J. Adipose tissue and its role in organ crosstalk. Acta Physiol. 210, 733-753 (2014
    • (2014) Acta Physiol , vol.210 , pp. 733-753
    • Romacho, T.1    Elsen, M.2    Rohrborn, D.3    Eckel, J.4
  • 22
    • 33845864967 scopus 로고    scopus 로고
    • Adipocytes as regulators of energy balance and glucose homeostasis
    • Rosen, E. D., & Spiegelman, B. M. Adipocytes as regulators of energy balance and glucose homeostasis. Nature 444, 847-853 (2006
    • (2006) Nature , vol.444 , pp. 847-853
    • Rosen, E.D.1    Spiegelman, B.M.2
  • 23
    • 79251541159 scopus 로고    scopus 로고
    • Dipeptidyl peptidase IV inhibitor sitagliptin reduces local inflammation in adipose tissue and in pancreatic islets of obese mice
    • Dobrian A. D., et al. Dipeptidyl peptidase IV inhibitor sitagliptin reduces local inflammation in adipose tissue and in pancreatic islets of obese mice. Am J Physiol Endocrinol Metab 300, E410-21 (2011
    • (2011) Am J Physiol Endocrinol Metab , vol.300 , pp. E410-E421
    • Dobrian, A.D.1
  • 24
    • 0030200944 scopus 로고    scopus 로고
    • Apintu novel human CCAAT/enhancer binding protein gene, C/EBPepsilon, is expressed in cells of lymphoid and myeloid lineages and is localized on chromosome 14q11.2 close to the T-cell receptor alpha/delta locus
    • Antonson, P., Stellan, B., Yamanaka, R., & Xanthopoulos, K. G. Apintu novel human CCAAT/enhancer binding protein gene, C/EBPepsilon, is expressed in cells of lymphoid and myeloid lineages and is localized on chromosome 14q11.2 close to the T-cell receptor alpha/delta locus. Genomics 35, 30-38 (1996
    • (1996) Genomics , vol.35 , pp. 30-38
    • Antonson, P.1    Stellan, B.2    Yamanaka, R.3    Xanthopoulos, K.G.4
  • 25
    • 0031008479 scopus 로고    scopus 로고
    • CCAAT/enhancer binding protein epsilon is preferentially up-regulated during granulocytic differentiation and its functional versatility is determined by alternative use of promoters and differential splicing
    • Yamanaka R., et al. CCAAT/enhancer binding protein epsilon is preferentially up-regulated during granulocytic differentiation and its functional versatility is determined by alternative use of promoters and differential splicing. Proc. Natl. Acad. Sci. USA 94, 6462-6467 (1997
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 6462-6467
    • Yamanaka, R.1
  • 26
    • 0037326196 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-? Coactivator 1α (PGC-1α ): Transcriptional coactivator and metabolic regulator
    • Puigserver, P., & Spiegelman, B. M. Peroxisome proliferator-activated receptor-? coactivator 1α (PGC-1α ): Transcriptional coactivator and metabolic regulator. Endocr. Rev. 24, 78-90 (2003
    • (2003) Endocr. Rev , vol.24 , pp. 78-90
    • Puigserver, P.1    Spiegelman, B.M.2
  • 27
    • 50649097541 scopus 로고    scopus 로고
    • Fat and beyond: The diverse biology of PPARgamma
    • Tontonoz, P., & Spiegelman, B. M. Fat and beyond: the diverse biology of PPARgamma. Annu. Rev. Biochem. 77, 289-312 (2008
    • (2008) Annu. Rev. Biochem , vol.77 , pp. 289-312
    • Tontonoz, P.1    Spiegelman, B.M.2
  • 28
    • 33947248112 scopus 로고    scopus 로고
    • Pref-1 (preadipocyte factor 1) activates the mek/extracellular signal-regulated kinase pathway to inhibit adipocyte differentiation
    • Kim, K. A., Kim, J. H., Wang, Y., & Sul, H. S. Pref-1 (Preadipocyte Factor 1) Activates the MEK/Extracellular Signal-Regulated Kinase Pathway to Inhibit Adipocyte Differentiation. Mol. Cell. Biol. 27, 3480-3492 (2007
    • (2007) Mol. Cell. Biol , vol.27 , pp. 3480-3492
    • Kim, K.A.1    Kim, J.H.2    Wang, Y.3    Sul, H.S.4
  • 29
    • 77954364477 scopus 로고    scopus 로고
    • Pref-1 interacts with fibronectin to inhibit adipocyte differentiation
    • Wang, Y., Zhao, L., Smas, C., & Sul, H. S. Pref-1 Interacts with Fibronectin to Inhibit Adipocyte Differentiation. Mol. Cell. Biol. 30, 2294-2308 (2010
    • (2010) Mol. Cell. Biol , vol.30 , pp. 2294-2308
    • Wang, Y.1    Zhao, L.2    Smas, C.3    Sul, H.S.4
  • 30
    • 33748942837 scopus 로고    scopus 로고
    • Transcriptional control of adipocyte formation
    • Farmer S. R. Transcriptional control of adipocyte formation. Cell Metab. 4 263-73 (2006
    • (2006) Cell Metab , vol.4 , pp. 263-273
    • Farmer, S.R.1
  • 31
    • 79960786696 scopus 로고    scopus 로고
    • Glitazone-like action of glimepiride and glibenclamide in primary human adipocytes
    • Mayer, P., Haas, B., Celner, J., Enzmann, H., & Pfeifer, A. Glitazone-like action of glimepiride and glibenclamide in primary human adipocytes. Diabetes Obes. Metab. 13, 791-799 (2011
    • (2011) Diabetes Obes. Metab , vol.13 , pp. 791-799
    • Mayer, P.1    Haas, B.2    Celner, J.3    Enzmann, H.4    Pfeifer, A.5
  • 32
    • 33845325476 scopus 로고    scopus 로고
    • Adipocyte differentiation from the inside out
    • Rosen, E. D., & MacDougald, O. A. Adipocyte differentiation from the inside out. Nat. Rev. Mol. Cell. Biol. 7, 885-896 (2006
    • (2006) Nat. Rev. Mol. Cell. Biol , vol.7 , pp. 885-896
    • Rosen, E.D.1    MacDougald, O.A.2
  • 33
    • 80054911514 scopus 로고    scopus 로고
    • Forming functional fat: A growing understanding of adipocyte differentiation
    • Cristancho, A. G., & Lazar, M. A. Forming functional fat: a growing understanding of adipocyte differentiation. Nat. Rev. Mol. Cell. Biol. 12, 722-734 (2011
    • (2011) Nat. Rev. Mol. Cell. Biol , vol.12 , pp. 722-734
    • Cristancho, A.G.1    Lazar, M.A.2
  • 35
    • 33746490142 scopus 로고    scopus 로고
    • Extra-enzymatic roles of DPIV and FAP in cell adhesion and migration on collagen and fibronectin
    • Wang, X. M., Yu, D. M. T., McCaughan, G. W., & Gorrell, M. D. Extra-enzymatic roles of DPIV and FAP in cell adhesion and migration on collagen and fibronectin. Adv. Exp. Med. Biol. 575, 213-222 (2006
    • (2006) Adv. Exp. Med. Biol , vol.575 , pp. 213-222
    • Wang, X.M.1    Yu, D.M.T.2    McCaughan, G.W.3    Gorrell, M.D.4
  • 36
    • 84938784378 scopus 로고    scopus 로고
    • Inhibition of dipeptidyl peptidase 8/9 impairs preadipocyte differentiation
    • Han, R., Wang, X., Bachovchin, W., Zukowska, Z., & Osborn, J. W. Inhibition of dipeptidyl peptidase 8/9 impairs preadipocyte differentiation. Sci, Rep. 5, 12348 (2015
    • (2015) Sci, Rep , vol.5 , pp. 12348
    • Han, R.1    Wang, X.2    Bachovchin, W.3    Zukowska, Z.4    Osborn, J.W.5
  • 37
    • 84887431711 scopus 로고    scopus 로고
    • Brown and beige fat: Development, function and therapeutic potential
    • Harms, M., & Seale, P. Brown and beige fat: development, function and therapeutic potential. Nat. Med. 19, 1252-1263 (2013
    • (2013) Nat. Med , vol.19 , pp. 1252-1263
    • Harms, M.1    Seale, P.2
  • 38
    • 84873518501 scopus 로고    scopus 로고
    • Adaptive thermogenesis in adipocytes: Is beige the new brown?
    • Wu, J., Cohen, P., & Spiegelman, B. M. Adaptive thermogenesis in adipocytes: Is beige the new brown? Genes Dev. 27, 234-250 (2013
    • (2013) Genes Dev , vol.27 , pp. 234-250
    • Wu, J.1    Cohen, P.2    Spiegelman, B.M.3
  • 39
    • 84901462102 scopus 로고    scopus 로고
    • Regulation of dipeptidyl peptidase 4 production in adipocytes by glucose
    • Das, S. S., et al. Regulation of dipeptidyl peptidase 4 production in adipocytes by glucose. Diabetes, Metab. Syndr. Obes. Targets Ther. 7, 185-194 (2014
    • (2014) Diabetes Metab. Syndr. Obes. Targets Ther , vol.7 , pp. 185-194
    • Das, S.S.1


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