Age-Dependent Changes in the Pulmonary Renin-Angiotensin System Are Associated with Severity of Lung Injury in a Model of Acute Lung Injury in Rats

Critical Care Medicine

Volumn 44, Issue 12, 2016, Pages e1226-e1235

  Schouten, Laura R A ^a   Helmerhorst, Hendrik J F ^a,b   Wagenaar, Gerry T M ^b   Haltenhof, Tom ^c   Lutter, René ^a   Roelofs, Joris J T H ^a   Van Woensel, Job B M ^a   Van Kaam, Anton H L C ^a   Bos, Albert P ^a   Schultz, Marcus J ^a   Walther, Thomas ^c,d   Wösten Van Asperen, Roelie M ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF LEIPZIG   (Germany)

^d UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

acute respiratory distress syndrome; aging; angiotensin converting enzyme; lipopolysaccharide; lung injury; mechanical ventilation

Indexed keywords

ADAM PROTEIN; ADAM9 PROTEIN; ANGIOTENSIN CONVERTING ENZYME 2; DIPEPTIDYL CARBOXYPEPTIDASE; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ADULT; AGED; AGING; ANIMAL EXPERIMENT; ARTICLE; ARTIFICIAL VENTILATION; BRONCHOALVEOLAR LAVAGE FLUID; CONTROLLED STUDY; GROUPS BY AGE; HISTOPATHOLOGY; INFANT; INFLAMMATION; INJURY SEVERITY; JUVENILE; LABORATORY; LIPOPOLYSACCHARIDE-INDUCED ACUTE LUNG INJURY; LUNG; MALE; MEDIATOR; MEDICAL RESEARCH; NONHUMAN; OXIDATIVE STRESS; PNEUMONIA; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN FOLDING; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SIGNAL TRANSDUCTION; ACUTE LUNG INJURY; AGE; ANIMAL; PATHOPHYSIOLOGY; PHYSIOLOGY; RESPIRATORY DISTRESS SYNDROME, ADULT; WISTAR RAT;

ACUTE LUNG INJURY; AGE FACTORS; ANIMALS; LUNG; MALE; RATS; RATS, WISTAR; RENIN-ANGIOTENSIN SYSTEM; RESPIRATORY DISTRESS SYNDROME, ADULT;

EID: 84981485548     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0000000000002008     Document Type: Article

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