Effects of age on the synergistic interactions between lipopolysaccharide and mechanical ventilation in mice

American Journal of Respiratory Cell and Molecular Biology

Volumn 43, Issue 4, 2010, Pages 475-486

  Smith, Lincoln S ^a   Gharib, Sina A ^a,b,c   Frevert, Charles W ^a   Martin, Thomas R ^a,d  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b USA   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d VA Puget Sound   (United States)

Author keywords

Adult respiratory distress syndrome; Inflammation; Oligonucleotide array sequence analysis

Indexed keywords

LIPOPOLYSACCHARIDE; OLIGONUCLEOTIDE; TRANSFORMING GROWTH FACTOR BETA; CYTOKINE;

ADULT RESPIRATORY DISTRESS SYNDROME; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL VENTILATION; BREATHING RATE; ESCHERICHIA COLI; FEMALE; GENE EXPRESSION; LUNG LAVAGE; MALE; MOUSE; NONHUMAN; PNEUMONIA; SEQUENCE ANALYSIS; ANIMAL; C57BL MOUSE; CLUSTER ANALYSIS; DRUG EFFECT; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETIC TRANSCRIPTION; GENETICS; LUNG; MULTIGENE FAMILY; NEUTROPHIL; PATHOLOGY; PERMEABILITY; PRINCIPAL COMPONENT ANALYSIS; SECRETION;

ANIMALIA; ESCHERICHIA COLI; MUS;

AGING; ANIMALS; CLUSTER ANALYSIS; CYTOKINES; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; LIPOPOLYSACCHARIDES; LUNG; MALE; MICE; MICE, INBRED C57BL; MULTIGENE FAMILY; NEUTROPHILS; PERMEABILITY; PNEUMONIA; PRINCIPAL COMPONENT ANALYSIS; RESPIRATION, ARTIFICIAL; TRANSCRIPTION, GENETIC;

EID: 77958138251     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2009-0039OC     Document Type: Article

References (70)

1. Rubenfeld GD, Caldwell E, Peabody E, Weaver J, Martin DP, Neff M, Stern EJ, Hudson LD. Incidence and outcomes of acute lung injury. N Engl J Med 2005;353:1685-1693. (Pubitemid 41464707)
2. ARDSNet. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 2000;342:1301-1308.
3. Flori HR, Glidden DV, Rutherford GW, Matthay MA. Pediatric acute lung injury: prospective evaluation of risk factors associated with mortality. Am J Respir Crit Care Med 2005;171:995-1001.
4. Hudson LD, Milberg JA, Anardi D, Maunder RJ. Clinical risks for development of the acute respiratory distress syndrome. Am J Respir Crit Care Med 1995;151:293-301.
5. Martin TR, Rubenfeld GD, Ruzinski JT, Goodman RB, Steinberg KP, Leturcq DJ, Moriarty AM, Raghu G, Baughman RP, Hudson LD. Relationship between soluble cd14, lipopolysaccharide binding protein, and the alveolar inflammatory response in patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 1997;155:937-944.
6. Tremblay LN, Slutsky AS. Ventilator-induced lung injury: from the bench to the bedside. Intensive Care Med 2006;32:24-33.
7. Burri PH, West JB, Crystal RG, Weibel ER, Barnes PJ. Postnatal development and growth. The lung: scientific foundations. Philadelphia, PA: Lippincott-Raven; 1997. pp. 1013-1026.
8. Warburton D, Schwarz M, Tefft D, Flores-Delgado G, Anderson KD, Cardoso WV. The molecular basis of lung morphogenesis. Mech Dev 2000;92:55-81.
9. Wohl MEB, Chernick V, Boat TF, Kendig EL. Developmental physiology of the respiratory system. In: Kendig's disorders of the respiratory tract in children. Philadelphia, PA: W.B. Saunders Company; 1998. pp. 19-27.
10. Martin TR, Ruzinski JT, Wilson CB, Skerrett SJ. Effects of endotoxin in the lungs of neonatal rats: age-dependent impairment of the inflammatory response. J Infect Dis 1995;171:134-144.
11. Qing G, Rajaraman K, Bortolussi R. Diminished priming of neonatal polymorphonuclear leukocytes by lipopolysaccharide is associated with reduced cd14 expression. Infect Immun 1995;63:248-252.
12. Yan SR, Qing G, Byers DM, Stadnyk AW, Al-Hertani W, Bortolussi R. Role of myd88 in diminished tumor necrosis factor alpha production by newborn mononuclear cells in response to lipopolysaccharide. Infect Immun 2004;72:1223-1229.
13. Alvira CM, Abate A, Yang G, Dennery PA, Rabinovitch M. Nuclear factor-kb activation in neonatal mouse lung protects against lipopolysaccharide-induced inflammation. Am J Respir Crit Care Med 2007;175:805-815. (Pubitemid 46631792)
14. Warburton D, Bellusci S. The molecular genetics of lung morphogenesis and injury repair. Paediatr Respir Rev 2004;5:S283-S287.
15. Ware LB, Matthay MA. Keratinocyte and hepatocyte growth factors in the lung: roles in lung development, inflammation, and repair. Am J Physiol Lung Cell Mol Physiol 2002;282:L924-L940.
16. Whitsett JA. Intrinsic and innate defenses in the lung: Intersection of pathways regulating lung morphogenesis, host defense, and repair. J Clin Invest 2002;109:565-569.
17. Whitsett JA, Bachurski CJ, Barnes KC, Bunn PA Jr, Case LM, Cook DN, Crooks D, Duncan MW, Dwyer-Nield L, Elston RC, et al. Functional genomics of lung disease. Am J Respir Cell Mol Biol 2004;31:S1-S81.
18. Copland IB, Martinez F, Kavanagh BP, Engelberts D, McKerlie C, Belik J, Post M. High tidal volume ventilation causes different inflammatory responses in newborn versus adult lung. Am J Respir Crit Care Med 2004;169:739-748. (Pubitemid 38338927)
19. Kornecki A, Tsuchida S, Ondiveeran HK, Engelberts D, Frndova H, Tanswell AK, Post M, McKerlie C, Belik J, Fox-Robichaud A, et al. Lung development and susceptibility to ventilator-induced lung injury. Am J Respir Crit Care Med 2005;171:743-752. (Pubitemid 40471145)
20. Amy RW, Bowes D, Burri PH, Haines J, Thurlbeck WM. Postnatal growth of the mouse lung. J Anat 1977;124:131-151.
21. Skerrett SJ, Martin TR, Chi EY, Peschon JJ, Mohler KM, Wilson CB. Role of the type 1 TNF receptor in lung inflammation after inhalation of endotoxin or Pseudomonas aeruginosa. Am J Physiol 1999;276:L715-L727.
22. Tankersley CG, Fitzgerald RS, Levitt RC, Mitzner WA, Ewart SL, Kleeberger SR. Genetic control of differential baseline breathing pattern. J Appl Physiol 1997;82:874-881.
23. Allen GB, Suratt BT, Rinaldi L, Petty JM, Bates JHT. Choosing the frequency of deep inflation in mice: balancing recruitment against ventilator-induced lung injury. Am J Physiol Lung Cell Mol Physiol 2006;291:L710-L717.
24. Bolstad BM, Irizarry RA, Astrand M, Speed TP. A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics 2003;19:185-193.
25. Saeed AI, Sharov V, White J, Li J, Liang W, Bhagabati N, Braisted J, Klapa M, Currier T, Thiagarajan M, et al. Tm4: a free, open-source system for microarray data management and analysis. Biotechniques 2003;34:374-378.
26. Raychaudhuri S, Stuart JM, Altman RB. Principal components analysis to summarize microarray experiments: application to sporulation time series. Pac Symp Biocomput 2000;:455-466.
27. Baldi P, Long AD. A Bayesian framework for the analysis of microarray expression data: regularized t-test and statistical inferences of gene changes. Bioinformatics 2001;17:509-519.
28. Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Statist Soc B 1995;1:289-300.
29. Dennis G Jr, Sherman BT, Hosack DA, Yang J, Gao W, Lane HC, Lempicki RA. David: database for annotation, visualization, and integrated discovery. Genome Biol 2003;4:3.
30. Calvano SE, Xiao W, Richards DR, Felciano RM, Baker HV, Cho RJ, Chen RO, Brownstein BH, Cobb JP, Tschoeke SK, et al. A network-based analysis of systemic inflammation in humans. Nature 2005;437:1032-1037.
31. Yamamoto M, Sato S, Mori K, Hoshino K, Takeuchi O, Takeda K, Akira S. Cutting edge: a novel toll/il-1 receptor domain-containing adapter that preferentially activates the IFN-b promoter in the toll-like receptor signaling. J Immunol 2002;169:6668-6672.
32. Yamamoto M, Sato S, Hemmi H, Hoshino K, Kaisho T, Sanjo H, Takeuchi O, Sugiyama M, Okabe M, Takeda K, et al. Role of adaptor TRIF in the myd88-independent toll-like receptor signaling pathway. Science 2003;301:640-643. (Pubitemid 36927946)
33. Molloy E, O'Neill AJ, Doyle B, Grantham J, Taylor C, Sheridan-Pereira M, Fitzpatrick J, Webb D, Watson RW. Effects of heat shock and hypoxia on neonatal neutrophil lipopolysaccharide responses: altered apoptosis, toll-like receptor-4 and cd11b expression compared with adults. Biol Neonate 2006;90:34-39.
34. Wurfel MM. Microarray-based analysis of ventilator-induced lung injury. Proc Am Thorac Soc 2007;4:77-84.
35. Patton LM, Saggart BS, Ahmed NK, Leff JA, Repine JE. Interleukin-1 beta-induced neutrophil recruitment and acute lung injury in hamsters. Inflammation 1995;19:23-29.
36. Park WY, Goodman RB, Steinberg KP, Ruzinski JT, Radella F III, Park DR, Pugin J, Skerrett SJ, Hudson LD, Martin TR. Cytokine balance in the lungs of patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 2001;164:1896-1903.
37. Pugin J, Ricou B, Steinberg KP, Suter PM, Martin TR. Proinflammatory activity in bronchoalveolar lavage fluids from patients with ARDS, a prominent role for interleukin-1. Am J Respir Crit Care Med 1996;153:1850-1856. (Pubitemid 26187910)
38. Smith LS, Kajikawa O, Elson G, Wick M, Mongovin S, Kosco-Vilbois M, Martin TR, Frevert CW. Effect of tlr4 blockade on pulmonary inflammation caused by mechanical ventilation and bacterial endotoxin. Exp Lung Res 2008;34:225-243.
39. Moriyama K, Ishizaka A, Nakamura M, Kubo H, Kotani T, Yamamoto S, Ogawa EN, Kajikawa O, Frevert CW, Kotake Y, et al. Enhancement of the endotoxin recognition pathway by ventilation with a large tidal volume in rabbits. Am J Physiol Lung Cell Mol Physiol 2004;286:L1114-L1121. (Pubitemid 38656645)
40. Martin TR, Mongovin SM, Tobias PS, Mathison JC, Moriarty AM, Leturcq DJ, Ulevitch RJ. The cd14 differentiation antigen mediates the development of endotoxin responsiveness during differentiation of mononuclear phagocytes. J Leukoc Biol 1994;56:1-9.
41. Altemeier WA, Matute-Bello G, Gharib SA, Glenny RW, Martin TR, Liles WC. Modulation of lipopolysaccharide-induced gene transcription and promotion of lung injury by mechanical ventilation. J Immunol 2005;175:3369-3376. (Pubitemid 41170559)
42. Ye SQ, Zhang LQ, Adyshev D, Usatyuk PV, Garcia AN, Lavoie TL, Verin AD, Natarajan V, Garcia JG. Pre-b-cell-colony-enhancing factor is critically involved in thrombin-induced lung endothelial cell barrier dysregulation. Microvasc Res 2005;70:142-151.
43. Simon BA, Easley RB, Grigoryev DN, Ma S-F, Ye SQ, Lavoie T, Tuder RM, Garcia JGN. Microarray analysis of regional cellular responses to local mechanical stress in acute lung injury. Am J Physiol Lung Cell Mol Physiol 2006;291:L851-L861.
44. Luk T, Malam Z, Marshall JC. Pre-b cell colony-enhancing factor (PBEF)/visfatin: a novel mediator of innate immunity. J Leukoc Biol 2008;83:804-816.
45. Jia SH, Li Y, Parodo J, Kapus A, Fan L, Rotstein OD, Marshall JC. Preb cell colony-enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. J Clin Invest 2004;113:1318-1327. (Pubitemid 39069931)
46. Ognjanovic S, Bryant-Greenwood GD. Pre-b-cell colony-enhancing factor, a novel cytokine of human fetal membranes. Am J Obstet Gynecol 2002;187:1051-1058.
47. Moschen AR, Kaser A, Enrich B, Mosheimer B, Theurl M, Niederegger H, Tilg H. Visfatin, an adipocytokine with proinflammatory and immunomodulating properties. J Immunol 2007;178:1748-1758.
48. Mor A, Keren G, Kloog Y, George J. N-ras or k-ras inhibition increases the number and enhances the function of foxp3 regulatory T cells. Eur J Immunol 2008;38:1493-1502.
49. Pelengaris S, Khan M, Evan G. C-myc: more than just a matter of life and death. Nat Rev Cancer 2002;2:764-776. (Pubitemid 37328911)
50. Ma SF, Grigoryev DN, Taylor AD, Nonas S, Sammani S, Ye SQ, Garcia JG. Bioinformatic identification of novel early stress response genes in rodent models of lung injury. Am J Physiol Lung Cell Mol Physiol 2005;289:L468-L477.
51. Yao H, Yang SR, Edirisinghe I, Rajendrasozhan S, Caito S, Adenuga D, O'Reilly MA, Rahman I. Disruption of p21 attenuates lung inflammation induced by cigarette smoke, LPS, and FMLP in mice. Am J Respir Cell Mol Biol 2008;39:7-18.
52. Perl AK, Hokuto I, Impagnatiello MA, Christofori G, Whitsett JA. Temporal effects of sprouty on lung morphogenesis. Dev Biol 2003;258:154-168.
53. Tassi E, Al-Attar A, Aigner A, Swift MR, McDonnell K, Karavanov A, Wellstein A. Enhancement of fibroblast growth factor (FGF) activity by an FGF-binding protein. J Biol Chem 2001;276:40247-40253. (Pubitemid 37391445)
54. Bartram U, Speer CP. The role of transforming growth factor beta in lung development and disease. Chest 2004;125:754-765. (Pubitemid 38223659)
55. Upadhyay D, Correa-Meyer E, Sznajder JI, Kamp DW. Fgf-10 prevents mechanical stretch-induced alveolar epithelial cell DNA damage via MAPK activation. Am J Physiol Lung Cell Mol Physiol 2003;284:L350-L359.
56. Gale M Jr, Foy EM. Evasion of intracellular host defence by hepatitis c virus. Nature 2005;436:939-945.
57. Bruce MC, Honaker CE, Cross RJ. Lung fibroblasts undergo apoptosis following alveolarization. Am J Respir Cell Mol Biol 1999;20:228-236.
58. Martin TR, Nakamura M, Matute-Bello G. The role of apoptosis in acute lung injury. Crit Care Med 2003; 31(4, Suppl)S184-S188. (Pubitemid 36458165)
59. He CH, Waxman AB, Lee CG, Link H, Rabach ME, Ma B, Chen Q, Zhu Z, Zhong M, Nakayama K, et al. Bcl-2-related protein A1 is an endogenous and cytokine-stimulated mediator of cytoprotection in hyperoxic acute lung injury. J Clin Invest 2005;115:1039-1048. (Pubitemid 40489409)
60. Chang L, Karin M. Mammalian MAP kinase signalling cascades. Nature 2001;410:37-40. (Pubitemid 32225829)
61. Dolinay T, Wu W, Kaminski N, Ifedigbo E, Kaynar A, Szilasi M, Watkins S, Ryter S, Hoetzel A, Choi A, et al. Mitogen-activated protein kinases regulate susceptibility to ventilator-induced lung injury. PLoS One 2008;3:e1601.
62. Nakaya T, Kawai T, Suzuki T. Regulation of fe65 nuclear translocation and function by amyloid beta-protein precursor in osmotically stressed cells. J Biol Chem 2008;283:19119-19131.
63. Checkley W, Brower R, Korpak A, Thompson BT, Investigators ARDSN. Effects of a clinical trial on mechanical ventilation practices in patients with acute lung injury. Am J Respir Crit Care Med 2008;177:1215-1222. (Pubitemid 351860930)
64. Kalhan R, Mikkelsen M, Dedhiya P, Christie J, Gaughan C, Lanken PN, Finkel B, Gallop R, Fuchs B. Underuse of lung protective ventilation: analysis of potential factors to explain physician behavior. Crit Care Med 2006;34:300-306. (Pubitemid 43145604)
65. Kavanagh BP. Therapeutic hypercapnia: careful science, better trials. Am J Respir Crit Care Med 2005;171:96-97.
66. Lang JD, Figueroa M, Sanders KD, Aslan M, Liu Y, Chumley P, Freeman BA. Hypercapnia via reduced rate and tidal volume contributes to lipopolysaccharide-induced lung injury. Am J Respir Crit Care Med 2005;171:147-157. (Pubitemid 40105414)
67. Takeshita K, Suzuki Y, Nishio K, Takeuchi O, Toda K, Kudo H, Miyao N, Ishii M, Sato N, Naoki K, et al. Hypercapnic acidosis attenuates endotoxin-induced nuclear factor-[kappa]b activation. Am J Respir Cell Mol Biol 2003;29:124-132. (Pubitemid 36783324)
68. Weber DJ, Rutala WA, Sickbert-Bennett EE, Samsa GP, Brown V, Niederman MS. Microbiology of ventilator-associated pneumonia compared with that of hospital-acquired pneumonia. Infect Control Hosp Epidemiol 2007;28:825-831.
69. Raymond J, Aujard Y. Nosocomial infections in pediatric patients: A European, multicenter prospective study. European study group. Infect Control Hosp Epidemiol 2000;21:260-263.
70. Grohskopf LA, Sinkowitz-Cochran RL, Garrett DO, Sohn AH, Levine GL, Siegel JD, Stover BH, Jarvis WR, Network PP. A national point-prevalence survey of pediatric intensive care unit-acquired infections in the united states. J Pediatr 2002;140:432-438.