Saikosaponin a inhibits LPS-induced inflammatory response by inducing liver X receptor alpha activation in primary mouse macrophages

Oncotarget

Volumn 7, Issue 31, 2016, Pages 48995-49007

  Wei, Zhengkai ^a   Wang, Jingjing ^a   Shi, Mingyu ^a   Liu, Weijian ^a   Yang, Zheng Tao ^a   Fu, Yunhe ^a  

^a JILIN UNIVERSITY   (China)

Author keywords

Immune response; Immunity; Immunology and Microbiology Section; IRF3; NF B; Saikosaponin a; TLR4Lipid raft

Indexed keywords

ABC TRANSPORTER A1; ABC TRANSPORTER G1; BETA INTERFERON; CHOLESTEROL; INTERFERON REGULATORY FACTOR 3; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; LIVER X RECEPTOR ALPHA; RANTES; SAIKOSAPONIN; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; ABCA1 PROTEIN, MOUSE; ANTIINFLAMMATORY AGENT; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE RECEPTOR; LIVER X RECEPTOR; NR1H3 PROTEIN, MOUSE; OLEANOLIC ACID; SAPONIN; TLR4 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL MEMBRANE; CELL VIABILITY; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; CYTOKINE RELEASE; ENDOTOXEMIA; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC TRANSFECTION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LIPID RAFT; MACROPHAGE; MALE; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; UPREGULATION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; CELL SURVIVAL; DRUG EFFECTS; FEMALE; MEMBRANE MICRODOMAIN; METABOLISM; SIGNAL TRANSDUCTION; TREATMENT OUTCOME;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ATP BINDING CASSETTE TRANSPORTER 1; CELL MEMBRANE; CELL SURVIVAL; CHOLESTEROL; CYTOKINES; ENDOTOXEMIA; FEMALE; INFLAMMATION; LIPOPOLYSACCHARIDE RECEPTORS; LIPOPOLYSACCHARIDES; LIVER X RECEPTORS; MACROPHAGES; MALE; MEMBRANE MICRODOMAINS; MICE; MICE, INBRED BALB C; NF-KAPPA B; OLEANOLIC ACID; SAPONINS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TREATMENT OUTCOME;

EID: 84981333717     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.9863     Document Type: Article

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