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Volumn 23, Issue 4, 2016, Pages 692-700

CUSTOM-SEQ: A prototype for oncology rapid learning in a comprehensive EHR environment

Author keywords

Electronic health records; Genomics; Health information management; Information science; Neoplasms; Precision medicine

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; GUANINE NUCLEOTIDE BINDING PROTEIN; DNA; EPIDERMAL GROWTH FACTOR;

EID: 84981288112     PISSN: 10675027     EISSN: 1527974X     Source Type: Journal    
DOI: 10.1093/jamia/ocw008     Document Type: Article
Times cited : (6)

References (58)
  • 3
    • 77957949436 scopus 로고    scopus 로고
    • Rapid-learning system for cancer care
    • Abernethy AP, Etheredge LM, Ganz PA, et al. Rapid-learning system for cancer care. J Clin Oncol. 2010; 28(27): 4268-4274.
    • (2010) J Clin Oncol , vol.28 , Issue.27 , pp. 4268-4274
    • Abernethy, A.P.1    Etheredge, L.M.2    Ganz, P.A.3
  • 4
    • 84880467544 scopus 로고    scopus 로고
    • Clinical analysis and interpretation of cancer genome data
    • Van Allen EM, Wagle N, Levy MA. Clinical analysis and interpretation of cancer genome data. J Clin Oncol. 2013; 31(15): 1825-1833.
    • (2013) J Clin Oncol , vol.31 , Issue.15 , pp. 1825-1833
    • Van Allen, E.M.1    Wagle, N.2    Levy, M.A.3
  • 7
    • 84875758730 scopus 로고    scopus 로고
    • Lessons from the cancer genome
    • Garraway LA, Lander ES. Lessons from the cancer genome. Cell. 2013; 153(1): 17-37.
    • (2013) Cell , vol.153 , Issue.1 , pp. 17-37
    • Garraway, L.A.1    Lander, E.S.2
  • 8
    • 33947101019 scopus 로고    scopus 로고
    • Patterns of somatic mutation in human cancer genomes
    • Greenman C, Stephens P, Smith R, et al. Patterns of somatic mutation in human cancer genomes. Nature. 2007; 446(7132): 153-158.
    • (2007) Nature , vol.446 , Issue.7132 , pp. 153-158
    • Greenman, C.1    Stephens, P.2    Smith, R.3
  • 9
    • 33947188719 scopus 로고    scopus 로고
    • Cancer: Drivers and passengers
    • Haber DA, Settleman J. Cancer: drivers and passengers. Nature. 2007; 446(7132): 145-146.
    • (2007) Nature , vol.446 , Issue.7132 , pp. 145-146
    • Haber, D.A.1    Settleman, J.2
  • 10
    • 84864258996 scopus 로고    scopus 로고
    • A landscape of driver mutations in melanoma
    • Hodis E, Watson IR, Kryukov GV, et al. A landscape of driver mutations in melanoma. Cell. 2012; 150(2): 251-263.
    • (2012) Cell , vol.150 , Issue.2 , pp. 251-263
    • Hodis, E.1    Watson, I.R.2    Kryukov, G.V.3
  • 11
    • 84861576201 scopus 로고    scopus 로고
    • The landscape of cancer genes and mutational processes in breast cancer
    • Stephens PJ, Tarpey PS, Davies H, et al. The landscape of cancer genes and mutational processes in breast cancer. Nature. 2012; 486(7403): 400-404.
    • (2012) Nature , vol.486 , Issue.7403 , pp. 400-404
    • Stephens, P.J.1    Tarpey, P.S.2    Davies, H.3
  • 12
    • 84901619679 scopus 로고    scopus 로고
    • Analysis of major known driver mutations and prognosis in resected adenosquamous lung carcinomas
    • Wang R, Pan Y, Li C, et al. Analysis of major known driver mutations and prognosis in resected adenosquamous lung carcinomas. J Thorac Oncol. 2014; 9(6): 760-768.
    • (2014) J Thorac Oncol , vol.9 , Issue.6 , pp. 760-768
    • Wang, R.1    Pan, Y.2    Li, C.3
  • 13
    • 79959795786 scopus 로고    scopus 로고
    • Improved survival with vemurafenib in melanoma with BRAF V600E mutation
    • Chapman PB, Hauschild A, Robert C, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med. 2011; 364(26): 2507-2516.
    • (2011) N Engl J Med , vol.364 , Issue.26 , pp. 2507-2516
    • Chapman, P.B.1    Hauschild, A.2    Robert, C.3
  • 14
    • 78049425319 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
    • Kwak EL, Bang YJ, Camidge DR, et al. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med. 2010; 363(18): 1693-16703.
    • (2010) N Engl J Med , vol.363 , Issue.18 , pp. 1693-16703
    • Kwak, E.L.1    Bang, Y.J.2    Camidge, D.R.3
  • 15
    • 84923762812 scopus 로고    scopus 로고
    • A new initiative on precision medicine
    • Collins FS, Varmus H. A new initiative on precision medicine. N Engl J Med. 2015; 372(9): 793-795.
    • (2015) N Engl J Med , vol.372 , Issue.9 , pp. 793-795
    • Collins, F.S.1    Varmus, H.2
  • 17
    • 84885735554 scopus 로고    scopus 로고
    • Mutational landscape and significance across 12 major cancer types
    • Kandoth C, McLellan MD, Vandin F, et al. Mutational landscape and significance across 12 major cancer types. Nature. 2013; 502(7471): 333-339.
    • (2013) Nature , vol.502 , Issue.7471 , pp. 333-339
    • Kandoth, C.1    McLellan, M.D.2    Vandin, F.3
  • 18
    • 84939864059 scopus 로고    scopus 로고
    • Vemurafenib in Multiple Nonmelanoma Cancers with BRAF V600 Mutations
    • Hyman DM, Puzanov I, Subbiah V, et al. Vemurafenib in Multiple Nonmelanoma Cancers with BRAF V600 Mutations. N Engl J Med. 2015; 373(8): 726-736.
    • (2015) N Engl J Med , vol.373 , Issue.8 , pp. 726-736
    • Hyman, D.M.1    Puzanov, I.2    Subbiah, V.3
  • 19
    • 84919862439 scopus 로고    scopus 로고
    • Secondary use of clinical data: The Vanderbilt approach
    • Danciu I, Cowan JD, Basford M, et al. Secondary use of clinical data: The Vanderbilt approach. J Biomed Inform. 2014;52:28-35.
    • (2014) J Biomed Inform , vol.52 , pp. 28-35
    • Danciu, I.1    Cowan, J.D.2    Basford, M.3
  • 20
    • 77954566882 scopus 로고    scopus 로고
    • Rapid targeted mutational analysis of human tumours: A clinical platform to guide personalized cancer medicine
    • Dias-Santagata D, Akhavanfard S, David SS, et al. Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine. EMBOMolMed. 2010; 2(5): 146-158.
    • (2010) EMBOMolMed , vol.2 , Issue.5 , pp. 146-158
    • Dias-santagata, D.1    Akhavanfard, S.2    David, S.S.3
  • 21
    • 78651079558 scopus 로고    scopus 로고
    • A platform for rapid detection of multiple oncogenic mutations with relevance to targeted therapy in non-small-cell lung cancer
    • Su Z, Dias-Santagata D, Duke M, et al. A platform for rapid detection of multiple oncogenic mutations with relevance to targeted therapy in non-small-cell lung cancer. JMolDiagn. 2011; 13(1): 74-84.
    • (2011) JMolDiagn , vol.13 , Issue.1 , pp. 74-84
    • Su, Z.1    Dias-santagata, D.2    Duke, M.3
  • 22
    • 84859972424 scopus 로고    scopus 로고
    • Routine multiplex mutational profiling of melanomas enables enrollment in genotype-driven therapeutic trials
    • Lovly CM, Dahlman KB, Fohn LE, et al. Routine multiplex mutational profiling of melanomas enables enrollment in genotype-driven therapeutic trials. PLoSOne. 2012; 7(4): e35309.
    • (2012) PLoSOne , vol.7 , Issue.4 , pp. e35309
    • Lovly, C.M.1    Dahlman, K.B.2    Fohn, L.E.3
  • 23
    • 84981215805 scopus 로고    scopus 로고
    • Routine multiplexed mutational analysis of colorectal cancers - a single institution experience
    • Fort Lauderdale, FL
    • Chan E, Goff L, Cardin D, et al. Routine multiplexed mutational analysis of colorectal cancers - a single institution experience. ECOG-ACRIN Young Investigators' Symposium. Fort Lauderdale, FL; 2012.
    • (2012) ECOG-ACRIN Young Investigators' Symposium
    • Chan, E.1    Goff, L.2    Cardin, D.3
  • 24
    • 84868331240 scopus 로고    scopus 로고
    • Translating genomic information into clinical medicine: Lung cancer as a paradigm
    • Levy MA, Lovly CM, Pao W. Translating genomic information into clinical medicine: lung cancer as a paradigm. Genome Res. 2012; 22(11): 2101-2108.
    • (2012) Genome Res , vol.22 , Issue.11 , pp. 2101-2108
    • Levy, M.A.1    Lovly, C.M.2    Pao, W.3
  • 27
    • 69549084684 scopus 로고    scopus 로고
    • The Shared Health Research Information Network (SHRINE): A prototype federated query tool for clinical data repositories
    • Weber GM, Murphy SN, McMurry AJ, et al. The Shared Health Research Information Network (SHRINE): a prototype federated query tool for clinical data repositories. JAm Med Inform Assoc. 2009; 16(5): 624-630.
    • (2009) JAm Med Inform Assoc , vol.16 , Issue.5 , pp. 624-630
    • Weber, G.M.1    Murphy, S.N.2    McMurry, A.J.3
  • 28
    • 18044385763 scopus 로고    scopus 로고
    • Agreement, the f-measure, and reliability in information retrieval
    • Hripcsak G, Rothschild AS. Agreement, the f-measure, and reliability in information retrieval. J Am Med Inform Assoc. 2005; 12(3): 296-298.
    • (2005) J Am Med Inform Assoc , vol.12 , Issue.3 , pp. 296-298
    • Hripcsak, G.1    Rothschild, A.S.2
  • 29
    • 84981215780 scopus 로고    scopus 로고
    • Feasibility and accuracy of extracting cancer stage information from narrative electronic health record data
    • Warner JL, Levy MA, Neuss MN. Feasibility and accuracy of extracting cancer stage information from narrative electronic health record data. J Oncol Pract. 2015.
    • (2015) J Oncol Pract
    • Warner, J.L.1    Levy, M.A.2    Neuss, M.N.3
  • 30
    • 40749097651 scopus 로고    scopus 로고
    • Methods for handling multiple testing
    • Rice TK, Schork NJ, Rao DC. Methods for handling multiple testing. Adv Genet. 2008;60:293-308.
    • (2008) Adv Genet , vol.60 , pp. 293-308
    • Rice, T.K.1    Schork, N.J.2    Rao, D.C.3
  • 31
    • 39649090053 scopus 로고    scopus 로고
    • The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: Guidelines for reporting observational studies
    • von Elm E, Altman DG, Egger M, et al. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. J Clin Epidemiol. 2008; 61(4): 344-349.
    • (2008) J Clin Epidemiol , vol.61 , Issue.4 , pp. 344-349
    • von Elm, E.1    Altman, D.G.2    Egger, M.3
  • 32
    • 84981258350 scopus 로고    scopus 로고
    • Medians and milestones in describing the path to cancer cures: Telling "Tails"
    • Hellmann MD, Kris MG, Rudin CM. Medians and milestones in describing the path to cancer cures: telling "Tails". JAMA Oncol. 2015:1-3.
    • (2015) JAMA Oncol , pp. 1-3
    • Hellmann, M.D.1    Kris, M.G.2    Rudin, C.M.3
  • 33
    • 4143066760 scopus 로고    scopus 로고
    • Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways
    • Sordella R, Bell DW, Haber DA, Settleman J. Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways. Science. 2004; 305(5687): 1163-1167.
    • (2004) Science , vol.305 , Issue.5687 , pp. 1163-1167
    • Sordella, R.1    Bell, D.W.2    Haber, D.A.3    Settleman, J.4
  • 34
    • 69949162760 scopus 로고    scopus 로고
    • Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
    • Mok TS, Wu YL, Thongprasert S, et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med. 2009; 361(10): 947-957.
    • (2009) N Engl J Med , vol.361 , Issue.10 , pp. 947-957
    • Mok, T.S.1    Wu, Y.L.2    Thongprasert, S.3
  • 36
    • 84941656198 scopus 로고    scopus 로고
    • Final overall survival results from a randomised, phase III study of erlotinib versus chemotherapy as first-line treatment of EGFR mutation-positive advanced non-small-cell lung cancer (OPTIMAL, CTONG-0802)
    • Zhou C, Wu YL, Chen G, et al. Final overall survival results from a randomised, phase III study of erlotinib versus chemotherapy as first-line treatment of EGFR mutation-positive advanced non-small-cell lung cancer (OPTIMAL, CTONG-0802). Ann Oncol. 2015; 26(9): 1877-1883.
    • (2015) Ann Oncol , vol.26 , Issue.9 , pp. 1877-1883
    • Zhou, C.1    Wu, Y.L.2    Chen, G.3
  • 37
    • 84886945315 scopus 로고    scopus 로고
    • Pros and cons of pragmatic clinical trials
    • Lurie JD, Morgan TS. Pros and cons of pragmatic clinical trials. J Comp Effectiveness Res. 2013; 2(1): 53-58.
    • (2013) J Comp Effectiveness Res , vol.2 , Issue.1 , pp. 53-58
    • Lurie, J.D.1    Morgan, T.S.2
  • 38
    • 84926178507 scopus 로고    scopus 로고
    • Outcomes of patients with chronic lymphocytic leukemia after discontinuing ibrutinib
    • Jain P, Keating M, Wierda W, et al. Outcomes of patients with chronic lymphocytic leukemia after discontinuing ibrutinib. Blood. 2015; 125(13): 2062-2067.
    • (2015) Blood , vol.125 , Issue.13 , pp. 2062-2067
    • Jain, P.1    Keating, M.2    Wierda, W.3
  • 39
    • 84925500147 scopus 로고    scopus 로고
    • Convergent loss of PTEN leads to clinical resistance to a PI(3)Kalpha inhibitor
    • Juric D, Castel P, Griffith M, et al. Convergent loss of PTEN leads to clinical resistance to a PI(3)Kalpha inhibitor. Nature. 2015; 518(7538): 240-244.
    • (2015) Nature , vol.518 , Issue.7538 , pp. 240-244
    • Juric, D.1    Castel, P.2    Griffith, M.3
  • 41
    • 85010773917 scopus 로고    scopus 로고
    • Artificial intelligence, big data, and cancer
    • Kantarjian H, Yu PP. Artificial intelligence, big data, and cancer. JAMA Oncol. 2015; 1(5): 573-574.
    • (2015) JAMA Oncol , vol.1 , Issue.5 , pp. 573-574
    • Kantarjian, H.1    Yu, P.P.2
  • 42
    • 84899757434 scopus 로고    scopus 로고
    • Beyond histology: Translating tumor genotypes into clinically effective targeted therapies
    • Meador CB, Micheel CM, Levy MA, et al. Beyond histology: translating tumor genotypes into clinically effective targeted therapies. Clin Cancer Res. 2014; 20(9): 2264-2275.
    • (2014) Clin Cancer Res , vol.20 , Issue.9 , pp. 2264-2275
    • Meador, C.B.1    Micheel, C.M.2    Levy, M.A.3
  • 43
    • 84891898344 scopus 로고    scopus 로고
    • Acquired resistance and clonal evolution in melanoma during BRAF inhibitor therapy
    • Shi H, Hugo W, Kong X, et al. Acquired resistance and clonal evolution in melanoma during BRAF inhibitor therapy. Cancer Discov. 2014; 4(1): 80-93.
    • (2014) Cancer Discov , vol.4 , Issue.1 , pp. 80-93
    • Shi, H.1    Hugo, W.2    Kong, X.3
  • 44
    • 84877100240 scopus 로고    scopus 로고
    • Analysis of tumor specimens at the time of acquired resistance to EGFR-TKI therapy in 155 patients with EGFR- mutantlung cancers
    • Yu HA, Arcila ME, Rekhtman N, et al. Analysis of tumor specimens at the time of acquired resistance to EGFR-TKI therapy in 155 patients with EGFR- mutantlung cancers. Clin Cancer Res. 2013; 19(8): 2240-2247.
    • (2013) Clin Cancer Res , vol.19 , Issue.8 , pp. 2240-2247
    • Yu, H.A.1    Arcila, M.E.2    Rekhtman, N.3
  • 45
    • 84887491073 scopus 로고    scopus 로고
    • Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing
    • Frampton GM, Fichtenholtz A, Otto GA, et al. Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing. Nat Biotechnol. 2013; 31(11): 1023-1031.
    • (2013) Nat Biotechnol , vol.31 , Issue.11 , pp. 1023-1031
    • Frampton, G.M.1    Fichtenholtz, A.2    Otto, G.A.3
  • 46
    • 77958478674 scopus 로고    scopus 로고
    • Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer
    • Pao W, Chmielecki J. Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer. Nat Rev Cancer. 2010; 10(11): 760-774.
    • (2010) Nat Rev Cancer , vol.10 , Issue.11 , pp. 760-774
    • Pao, W.1    Chmielecki, J.2
  • 47
    • 84930526399 scopus 로고    scopus 로고
    • ClinGen-the Clinical Genome Resource
    • Rehm HL, Berg JS, Brooks LD, et al. ClinGen-the Clinical Genome Resource. N Engl J Med. 2015; 372(23): 2235-2242.
    • (2015) N Engl J Med , vol.372 , Issue.23 , pp. 2235-2242
    • Rehm, H.L.1    Berg, J.S.2    Brooks, L.D.3
  • 48
    • 84944345463 scopus 로고    scopus 로고
    • Building the foundation for genomics in precision medicine
    • Aronson SJ, Rehm HL. Building the foundation for genomics in precision medicine. Nature. 2015; 526(7573): 336-342.
    • (2015) Nature , vol.526 , Issue.7573 , pp. 336-342
    • Aronson, S.J.1    Rehm, H.L.2
  • 49
    • 0030971490 scopus 로고    scopus 로고
    • Survival analysis in public health research
    • Lee ET, Go OT. Survival analysis in public health research. Ann Rev Public Health. 1997;18:105-134.
    • (1997) Ann Rev Public Health , vol.18 , pp. 105-134
    • Lee, E.T.1    Go, O.T.2
  • 51
    • 64249109679 scopus 로고    scopus 로고
    • EGFR and KRAS mutations in patients with adenocarcinoma of the lung
    • Jang TW, Oak CH, Chang HK, Suo SJ, Jung MH. EGFR and KRAS mutations in patients with adenocarcinoma of the lung. Korean J Int Med. 2009; 24(1): 48-54.
    • (2009) Korean J Int Med , vol.24 , Issue.1 , pp. 48-54
    • Jang, T.W.1    Oak, C.H.2    Chang, H.K.3    Suo, S.J.4    Jung, M.H.5
  • 53
    • 59049107421 scopus 로고    scopus 로고
    • Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi
    • Van Raamsdonk CD, Bezrookove V, Green G, et al. Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi. Nature. 2009; 457(7229): 599-602.
    • (2009) Nature , vol.457 , Issue.7229 , pp. 599-602
    • Van Raamsdonk, C.D.1    Bezrookove, V.2    Green, G.3
  • 54
    • 70249134535 scopus 로고    scopus 로고
    • Oncogenic GNAQ mutations are not correlated with disease-free survival in uveal melanoma
    • Bauer J, Kilic E, Vaarwater J, Bastian BC, Garbe C, de Klein A. Oncogenic GNAQ mutations are not correlated with disease-free survival in uveal melanoma. Br J Cancer.2009;101(5):813-815.
    • (2009) Br J Cancer , vol.101 , Issue.5 , pp. 813-815
    • Bauer, J.1    Kilic, E.2    Vaarwater, J.3    Bastian, B.C.4    Garbe, C.5    de Klein, A.6
  • 55
    • 4444344330 scopus 로고    scopus 로고
    • EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
    • Pao W, Miller V, Zakowski M, et al. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci USA. 2004; 101(36): 13306-13311.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.36 , pp. 13306-13311
    • Pao, W.1    Miller, V.2    Zakowski, M.3
  • 57
    • 33846563409 scopus 로고    scopus 로고
    • Why most published research findings are false
    • Ioannidis JP. Why most published research findings are false. PLoS Med. 2005; 2(8): e124.
    • (2005) PLoS Med , vol.2 , Issue.8 , pp. e124
    • Ioannidis, J.P.1
  • 58
    • 0027235861 scopus 로고
    • An introduction to the use of interim data analyses in clinical trials
    • Lewis RJ. An introduction to the use of interim data analyses in clinical trials. Ann Emerg Med. 1993; 22(9): 1463-1469.
    • (1993) Ann Emerg Med , vol.22 , Issue.9 , pp. 1463-1469
    • Lewis, R.J.1


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