Caenorhabditis elegans chronically exposed to a Mn/Zn ethylene-bis-dithiocarbamate fungicide show mitochondrial Complex I inhibition and increased reactive oxygen species

NeuroToxicology

Volumn 56, Issue , 2016, Pages 170-179

  Bailey, Denise C ^a   Todt, Callie E ^a   Orfield, Sarah E ^a   Denney, Rachel D ^a   Snapp, Isaac B ^a   Negga, Rekek ^a   Montgomery, Kara M ^a   Bailey, Andrew C ^a   Pressley, Aireal S ^a   Traynor, Wendy L ^a   Fitsanakis, Vanessa A ^a  

^a King University   (United States)

Author keywords

C. elegans; Complex I; Hydrogen peroxide; Mancozeb; Mitochondrial inhibition; Reactive oxygen species

Indexed keywords

GLUTATHIONE TRANSFERASE; HYDROETHIDINE; MANCOZEB; MANEB; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUPEROXIDE DISMUTASE; ADENOSINE TRIPHOSPHATE; FUNGICIDE; GREEN FLUORESCENT PROTEIN; HYDROGEN PEROXIDE; HYDROXYL RADICAL; MALONIC ACID; MALONIC ACID DERIVATIVE; SUCCINATE DEHYDROGENASE (UBIQUINONE);

ANALYSIS OF VARIANCE; ARTICLE; BREATHING; CAENORHABDITIS ELEGANS; CENTRIFUGATION; CHEMICAL ANALYSIS; CONTROLLED STUDY; CORTICAL SYNCHRONIZATION; ELECTROCHEMISTRY; ENVIRONMENTAL EXPOSURE; ENZYME INHIBITION; FLUORESCENCE MICROSCOPY; FUNGICIDE APPLICATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PRIORITY JOURNAL; UPREGULATION; ANIMAL; DRUG EFFECTS; GENETICS; METABOLISM;

ADENOSINE TRIPHOSPHATE; ANIMALS; CAENORHABDITIS ELEGANS; ELECTRON TRANSPORT COMPLEX I; ELECTRON TRANSPORT COMPLEX II; FUNGICIDES, INDUSTRIAL; GLUTATHIONE TRANSFERASE; GREEN FLUORESCENT PROTEINS; HYDROGEN PEROXIDE; HYDROXYL RADICAL; MALONATES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; OXYGEN CONSUMPTION; REACTIVE OXYGEN SPECIES; UP-REGULATION;

EID: 84981278150     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2016.07.011     Document Type: Article

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