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Volumn 23, Issue 4, 2016, Pages 796-801

Developing knowledge resources to support precision medicine: Principles from the Clinical Pharmacogenetics Implementation Consortium (CPIC)

Author keywords

Clinical decision support systems; Electronic health records; Knowledge bases; Pharmacogenetics; Precision medicine

Indexed keywords

ARTICLE; CLINICAL DECISION SUPPORT SYSTEM; ELECTRONIC HEALTH RECORD; HUMAN; KNOWLEDGE BASE; PERSONALIZED MEDICINE; PHARMACOGENETICS; POINT OF CARE SYSTEM; PRACTICE GUIDELINE; FACTUAL DATABASE;

EID: 84981165074     PISSN: 10675027     EISSN: 1527974X     Source Type: Journal    
DOI: 10.1093/jamia/ocw027     Document Type: Article
Times cited : (90)

References (48)
  • 1
    • 84923762812 scopus 로고    scopus 로고
    • A new initiative on precision medicine
    • Collins FS, Varmus H. A new initiative on precision medicine. N Engl J Med. 2015;372(9):793-795.
    • (2015) N Engl J Med. , vol.372 , Issue.9 , pp. 793-795
    • Collins, F.S.1    Varmus, H.2
  • 2
    • 84930535796 scopus 로고    scopus 로고
    • Precision medicine: personalized, problematic, and promising
    • Jameson JL, Longo DL. Precision medicine: personalized, problematic, and promising. N Engl J Med. 2015;372(23):2229-2234.
    • (2015) N Engl J Med. , vol.372 , Issue.23 , pp. 2229-2234
    • Jameson, J.L.1    Longo, D.L.2
  • 3
    • 84920866837 scopus 로고    scopus 로고
    • Preemptive clinical pharmacogenetics implementation: current programs in five US medical centers
    • Dunnenberger HM, Crews KR, Hoffman JM, et al. Preemptive clinical pharmacogenetics implementation: current programs in five US medical centers. Ann Rev Pharmcol Toxicol. 2015;55:89-106.
    • (2015) Ann Rev Pharmcol Toxicol. , vol.55 , pp. 89-106
    • Dunnenberger, H.M.1    Crews, K.R.2    Hoffman, J.M.3
  • 4
    • 84867848963 scopus 로고    scopus 로고
    • A clinician-driven automated system for integration of pharmacogenetic interpretations into an electronic medical record
    • Hicks JK, Crews KR, Hoffman JM, et al. A clinician-driven automated system for integration of pharmacogenetic interpretations into an electronic medical record. Clin Pharm Ther. 2012;92(5):563-566.
    • (2012) Clin Pharm Ther. , vol.92 , Issue.5 , pp. 563-566
    • Hicks, J.K.1    Crews, K.R.2    Hoffman, J.M.3
  • 5
    • 84885101900 scopus 로고    scopus 로고
    • Electronic health record design and implementation for pharmacogenomics: a local perspective
    • Peterson JF, Bowton E, Field JR, et al. Electronic health record design and implementation for pharmacogenomics: a local perspective. Genet Med. 2013;15(10):833-841.
    • (2013) Genet Med. , vol.15 , Issue.10 , pp. 833-841
    • Peterson, J.F.1    Bowton, E.2    Field, J.R.3
  • 6
    • 84896319867 scopus 로고    scopus 로고
    • PG4KDS: a model for the clinical implementation of pre-emptive pharmacogenetics
    • Hoffman JM, Haidar CE, Wilkinson MR, et al. PG4KDS: a model for the clinical implementation of pre-emptive pharmacogenetics. Am J Med Genet C Semin Med Genet. 2014;166C(1):45-55.
    • (2014) Am J Med Genet C Semin Med Genet. , vol.166C , Issue.1 , pp. 45-55
    • Hoffman, J.M.1    Haidar, C.E.2    Wilkinson, M.R.3
  • 7
    • 84880727398 scopus 로고    scopus 로고
    • The Pharmacogenomics Research Network Translational Pharmacogenetics Program: overcoming challenges of real-world implementation
    • Shuldiner AR, Relling MV, Peterson JF, et al. The Pharmacogenomics Research Network Translational Pharmacogenetics Program: overcoming challenges of real-world implementation. Clin Pharm Ther. 2013; 94(2):207-210.
    • (2013) Clin Pharm Ther. , vol.94 , Issue.2 , pp. 207-210
    • Shuldiner, A.R.1    Relling, M.V.2    Peterson, J.F.3
  • 8
    • 84893549013 scopus 로고    scopus 로고
    • Development and use of active clinical decision support for preemptive pharmacogenomics
    • Bell GC, Crews KR, Wilkinson MR, et al. Development and use of active clinical decision support for preemptive pharmacogenomics. J Am Med Inform Assoc. 2014;21(e1):e93-e99.
    • (2014) J Am Med Inform Assoc. , vol.21 , Issue.e1 , pp. e93-e99
    • Bell, G.C.1    Crews, K.R.2    Wilkinson, M.R.3
  • 9
    • 84896637856 scopus 로고    scopus 로고
    • Clinically actionable genotypes among 10,000 patients with preemptive pharmacogenomic testing
    • Van Driest SL, Shi Y, Bowton EA, et al. Clinically actionable genotypes among 10,000 patients with preemptive pharmacogenomic testing. Clin Pharm Ther. 2014;95(4):423-431.
    • (2014) Clin Pharm Ther. , vol.95 , Issue.4 , pp. 423-431
    • Van Driest, S.L.1    Shi, Y.2    Bowton, E.A.3
  • 10
    • 84862620703 scopus 로고    scopus 로고
    • Operational implementation of prospective genotyping for personalized medicine: the design of the Vanderbilt PREDICT project
    • Pulley JM, Denny JC, Peterson JF, et al. Operational implementation of prospective genotyping for personalized medicine: the design of the Vanderbilt PREDICT project. Clin Pharm Ther. 2012;92(1):87-95.
    • (2012) Clin Pharm Ther. , vol.92 , Issue.1 , pp. 87-95
    • Pulley, J.M.1    Denny, J.C.2    Peterson, J.F.3
  • 11
    • 84893097016 scopus 로고    scopus 로고
    • Preemptive genotyping for personalized medicine: design of the right drug, right dose, right time-using genomic data to individualize treatment protocol
    • Bielinski SJ, Olson JE, Pathak J, et al. Preemptive genotyping for personalized medicine: design of the right drug, right dose, right time-using genomic data to individualize treatment protocol. Mayo Clin Proc. 2014;89(1): 25-33.
    • (2014) Mayo Clin Proc. , vol.89 , Issue.1 , pp. 25-33
    • Bielinski, S.J.1    Olson, J.E.2    Pathak, J.3
  • 12
    • 84896319089 scopus 로고    scopus 로고
    • Genomic medicine implementation: learning by example
    • Williams MS. Genomic medicine implementation: learning by example. Am J Med Genet C Semin Med Genet. 2014;166C(1):8-14.
    • (2014) Am J Med Genet C Semin Med Genet. , vol.166C , Issue.1 , pp. 8-14
    • Williams, M.S.1
  • 13
    • 84953343333 scopus 로고    scopus 로고
    • Report of the AMIA EHR 2020 task force on the status and future direction of EHRs
    • ocv066
    • Payne TH, Corley S, Cullen TA, et al. Report of the AMIA EHR 2020 task force on the status and future direction of EHRs. J Am Med Inform Assoc. 2015;pii:ocv066.
    • (2015) J Am Med Inform Assoc.
    • Payne, T.H.1    Corley, S.2    Cullen, T.A.3
  • 14
    • 84857165460 scopus 로고    scopus 로고
    • Impact of data fragmentation across healthcare centers on the accuracy of a high-throughput clinical phenotyping algorithm for specifying subjects with type 2 diabetes mellitus
    • Wei WQ, Leibson CL, Ransom JE, et al. Impact of data fragmentation across healthcare centers on the accuracy of a high-throughput clinical phenotyping algorithm for specifying subjects with type 2 diabetes mellitus. J Am Med Inform Assoc. 2012;19(2):219-224.
    • (2012) J Am Med Inform Assoc. , vol.19 , Issue.2 , pp. 219-224
    • Wei, W.Q.1    Leibson, C.L.2    Ransom, J.E.3
  • 15
    • 0035173378 scopus 로고    scopus 로고
    • dbSNP: the NCBI database of genetic variation
    • Sherry ST, Ward MH, Kholodov M, et al. dbSNP: the NCBI database of genetic variation. Nucleic Acids Res. 2001;29(1):308-311.
    • (2001) Nucleic Acids Res. , vol.29 , Issue.1 , pp. 308-311
    • Sherry, S.T.1    Ward, M.H.2    Kholodov, M.3
  • 16
    • 84891809093 scopus 로고    scopus 로고
    • ClinVar: public archive of relationships among sequence variation and human phenotype
    • Landrum MJ, Lee JM, Riley GR, et al. ClinVar: public archive of relationships among sequence variation and human phenotype. Nucleic Acids Res. 2014;42:D980-D985.
    • (2014) Nucleic Acids Res. , vol.42 , pp. D980-D985
    • Landrum, M.J.1    Lee, J.M.2    Riley, G.R.3
  • 17
    • 0040920369 scopus 로고    scopus 로고
    • Online Mendelian Inheritance in Man
    • Accessed August 28
    • Online Mendelian Inheritance in Man. http://omim.org/. Accessed August 28, 2015.
    • (2015)
  • 18
    • 84946027595 scopus 로고    scopus 로고
    • Database resources of the National Center for Biotechnology Information
    • Coordinators NR. Database resources of the National Center for Biotechnology Information. Nucleic Acids Res. 2015;43:D6-D17.
    • (2015) Nucleic Acids Res. , vol.43 , pp. D6-D17
    • Coordinators, N.R.1
  • 19
    • 84875540793 scopus 로고    scopus 로고
    • Crossing the omic chasm: A time for omic ancillary systems
    • Starren J, Williams MS, Bottinger EP. Crossing the omic chasm: A time for omic ancillary systems. JAMA. 2013;309(12):1237-1238.
    • (2013) JAMA. , vol.309 , Issue.12 , pp. 1237-1238
    • Starren, J.1    Williams, M.S.2    Bottinger, E.P.3
  • 20
    • 84900854522 scopus 로고    scopus 로고
    • Incorporation of pharmacogenomics into routine clinical practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline development process
    • Caudle KE, Klein TE, Hoffman JM, et al. Incorporation of pharmacogenomics into routine clinical practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline development process. Curr Drug Metab. 2014;15(2):209-217.
    • (2014) Curr Drug Metab. , vol.15 , Issue.2 , pp. 209-217
    • Caudle, K.E.1    Klein, T.E.2    Hoffman, J.M.3
  • 21
    • 84899417586 scopus 로고    scopus 로고
    • Clinical Pharmacogenetics Implementation Consortium Guidelines for HLA-B Genotype and Abacavir Dosing: 2014 update
    • Martin MA, Hoffman JM, Freimuth RR, et al. Clinical Pharmacogenetics Implementation Consortium Guidelines for HLA-B Genotype and Abacavir Dosing: 2014 update. Clin Pharm Ther. 2014;95(5):499-500.
    • (2014) Clin Pharm Ther. , vol.95 , Issue.5 , pp. 499-500
    • Martin, M.A.1    Hoffman, J.M.2    Freimuth, R.R.3
  • 22
    • 84955325490 scopus 로고    scopus 로고
    • Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for human leukocyte antigen B (HLA-B) genotype and allopurinol dosing: 2015 update.
    • Epub ahead of print
    • Saito Y, Stamp LK, Caudle KE, et al. Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for human leukocyte antigen B (HLA-B) genotype and allopurinol dosing: 2015 update. Clin Pharm Ther. 2015, [Epub ahead of print, doi: 10.1002/cpt.161].
    • (2015) Clin Pharm Ther.
    • Saito, Y.1    Stamp, L.K.2    Caudle, K.E.3
  • 23
    • 84908220839 scopus 로고    scopus 로고
    • Clinical pharmacogenetics implementation consortium guidelines for CYP2C9 and HLA-B genotypes and phenytoin dosing
    • Caudle KE, Rettie AE, Whirl-Carrillo M, et al. Clinical pharmacogenetics implementation consortium guidelines for CYP2C9 and HLA-B genotypes and phenytoin dosing. Clin Pharm Ther. 2014;96(5):542-548.
    • (2014) Clin Pharm Ther. , vol.96 , Issue.5 , pp. 542-548
    • Caudle, K.E.1    Rettie, A.E.2    Whirl-Carrillo, M.3
  • 24
    • 84921691744 scopus 로고    scopus 로고
    • The clinical pharmacogenetics implementation consortium guideline for SLCO1B1 and simvastatin-induced myopathy: 2014 update
    • Ramsey LB, Johnson SG, Caudle KE, et al. The clinical pharmacogenetics implementation consortium guideline for SLCO1B1 and simvastatin-induced myopathy: 2014 update. Clin Pharm Ther. 2014;96(4):423-428.
    • (2014) Clin Pharm Ther. , vol.96 , Issue.4 , pp. 423-428
    • Ramsey, L.B.1    Johnson, S.G.2    Caudle, K.E.3
  • 25
    • 84962294272 scopus 로고    scopus 로고
    • Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors
    • Hicks JK, Bishop JR, Sangkuhl K, et al. Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors. Clin Pharm Ther. 2015;98(2):127-134.
    • (2015) Clin Pharm Ther. , vol.98 , Issue.2 , pp. 127-134
    • Hicks, J.K.1    Bishop, J.R.2    Sangkuhl, K.3
  • 26
    • 84962207669 scopus 로고    scopus 로고
    • Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP3A5 Genotype and Tacrolimus Dosing
    • Birdwell KA, Decker B, Barbarino JM, et al. Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP3A5 Genotype and Tacrolimus Dosing. Clin Pharm Ther. 2015;98(1):19-24.
    • (2015) Clin Pharm Ther. , vol.98 , Issue.1 , pp. 19-24
    • Birdwell, K.A.1    Decker, B.2    Barbarino, J.M.3
  • 27
    • 79959938418 scopus 로고    scopus 로고
    • Electronic medical records and personalized medicine
    • Hoffman MA, Williams MS. Electronic medical records and personalized medicine. Hum Genet. 2011;130(1):33-39.
    • (2011) Hum Genet. , vol.130 , Issue.1 , pp. 33-39
    • Hoffman, M.A.1    Williams, M.S.2
  • 28
    • 84885169965 scopus 로고    scopus 로고
    • Integration of genomics into the electronic health record: mapping terra incognita
    • Kannry JL, Williams MS. Integration of genomics into the electronic health record: mapping terra incognita. Genet Med. 2013;15(10):757-760.
    • (2013) Genet Med. , vol.15 , Issue.10 , pp. 757-760
    • Kannry, J.L.1    Williams, M.S.2
  • 29
    • 84890526744 scopus 로고    scopus 로고
    • Genetic data and electronic health records: a discussion of ethical, logistical and technological considerations
    • Shoenbill K, Fost N, Tachinardi U, Mendonca EA. Genetic data and electronic health records: a discussion of ethical, logistical and technological considerations. J Am Med Inform Assoc. 2014;21(1):171-180.
    • (2014) J Am Med Inform Assoc. , vol.21 , Issue.1 , pp. 171-180
    • Shoenbill, K.1    Fost, N.2    Tachinardi, U.3    Mendonca, E.A.4
  • 30
    • 84875927186 scopus 로고    scopus 로고
    • Genomic medicine, health information technology, and patient care
    • Chute CG, Kohane IS. Genomic medicine, health information technology, and patient care. JAMA. 2013;309(14):1467-1468.
    • (2013) JAMA. , vol.309 , Issue.14 , pp. 1467-1468
    • Chute, C.G.1    Kohane, I.S.2
  • 32
    • 84875939245 scopus 로고    scopus 로고
    • Implementing genomic medicine in the clinic: the future is here
    • Manolio TA, Chisholm RL, Ozenberger B, et al. Implementing genomic medicine in the clinic: the future is here. Genet Med. 2013;15(4): 258-267.
    • (2013) Genet Med. , vol.15 , Issue.4 , pp. 258-267
    • Manolio, T.A.1    Chisholm, R.L.2    Ozenberger, B.3
  • 33
  • 34
    • 84861868693 scopus 로고    scopus 로고
    • Technical desiderata for the integration of genomic data into Electronic Health Records
    • Masys DR, Jarvik GP, Abernethy NF, et al. Technical desiderata for the integration of genomic data into Electronic Health Records. J Biomed Inform. 2012;45(3):419-422.
    • (2012) J Biomed Inform. , vol.45 , Issue.3 , pp. 419-422
    • Masys, D.R.1    Jarvik, G.P.2    Abernethy, N.F.3
  • 35
    • 84908053030 scopus 로고    scopus 로고
    • Technical desiderata for the integration of genomic data with clinical decision support
    • Welch BM, Eilbeck K, Del Fiol G, Meyer LJ, Kawamoto K. Technical desiderata for the integration of genomic data with clinical decision support. J Biomed Inform. 2014;51:3-7.
    • (2014) J Biomed Inform. , vol.51 , pp. 3-7
    • Welch, B.M.1    Eilbeck, K.2    Del Fiol, G.3    Meyer, L.J.4    Kawamoto, K.5
  • 36
    • 84880383420 scopus 로고    scopus 로고
    • PharmGKB: the pharmacogenomics knowledge base
    • Thorn CF, Klein TE, Altman RB. PharmGKB: the pharmacogenomics knowledge base. Methods Mol Bio. 2013;1015:311-320.
    • (2013) Methods Mol Bio. , vol.1015 , pp. 311-320
    • Thorn, C.F.1    Klein, T.E.2    Altman, R.B.3
  • 37
    • 84866611528 scopus 로고    scopus 로고
    • Pharmacogenomics knowledge for personalized medicine
    • Whirl-Carrillo M, McDonagh E, Hebert J, et al. Pharmacogenomics knowledge for personalized medicine. Clin Pharm Ther. 2012;92(4):414-417.
    • (2012) Clin Pharm Ther. , vol.92 , Issue.4 , pp. 414-417
    • Whirl-Carrillo, M.1    McDonagh, E.2    Hebert, J.3
  • 38
    • 84981235021 scopus 로고    scopus 로고
    • CPIC Genes/ Drugs Legend
    • Accessed January 20
    • Clinical Pharmacogenetics Implementation Consortium(CPIC). CPIC Genes/ Drugs Legend. https://cpicpgx.org/genes-drugs/. Accessed January 20, 2016.
    • (2016)
  • 39
    • 33745388773 scopus 로고    scopus 로고
    • Using commercial knowledge bases for clinical decision support: opportunities, hurdles, and recommendations
    • Kuperman GJ, Reichley RM, Bailey TC. Using commercial knowledge bases for clinical decision support: opportunities, hurdles, and recommendations. J Am Med Inform Assoc. 2006;13(4):369-371.
    • (2006) J Am Med Inform Assoc. , vol.13 , Issue.4 , pp. 369-371
    • Kuperman, G.J.1    Reichley, R.M.2    Bailey, T.C.3
  • 40
    • 84893569478 scopus 로고    scopus 로고
    • A novel clinician interface to improve clinician access to up-to-date genetic results
    • Wilcox AR, Neri PM, Volk LA, et al. A novel clinician interface to improve clinician access to up-to-date genetic results. J Am Med Inform Assoc. 2014;21(e1):e117-e121.
    • (2014) J Am Med Inform Assoc. , vol.21 , Issue.e1 , pp. e117-e121
    • Wilcox, A.R.1    Neri, P.M.2    Volk, L.A.3
  • 41
    • 84952940623 scopus 로고    scopus 로고
    • CSER and eMERGE: current and potential state of the display of genetic information in the electronic health record.
    • ocv065
    • Shirts BH, Salama JS, Aronson SJ, et al. CSER and eMERGE: current and potential state of the display of genetic information in the electronic health record. J Am Med Inform Assoc. 2015:pii: ocv065.
    • (2015) J Am Med Inform Assoc.
    • Shirts, B.H.1    Salama, J.S.2    Aronson, S.J.3
  • 42
    • 84901827552 scopus 로고    scopus 로고
    • Integrating pharmacogenetic information and clinical decision support into the electronic health record
    • Goldspiel BR, Flegel WA, DiPatrizio G, et al. Integrating pharmacogenetic information and clinical decision support into the electronic health record. J Am Med Inform Assoc. 2014;21(3):522-528.
    • (2014) J Am Med Inform Assoc. , vol.21 , Issue.3 , pp. 522-528
    • Goldspiel, B.R.1    Flegel, W.A.2    DiPatrizio, G.3
  • 43
    • 84921648422 scopus 로고    scopus 로고
    • Design and anticipated outcomes of the eMERGE-PGx project: a multicenter pilot for preemptive pharmacogenomics in electronic health record systems
    • Rasmussen-Torvik LJ, Stallings SC, Gordon AS, et al. Design and anticipated outcomes of the eMERGE-PGx project: a multicenter pilot for preemptive pharmacogenomics in electronic health record systems. Clin Pharm Ther. 2014;96:482-489.
    • (2014) Clin Pharm Ther. , vol.96 , pp. 482-489
    • Rasmussen-Torvik, L.J.1    Stallings, S.C.2    Gordon, A.S.3
  • 44
    • 84930526399 scopus 로고    scopus 로고
    • ClinGen: The Clinical Genome Resource.
    • Rehm HL, Berg JS, Brooks LD, et al. ClinGen: The Clinical Genome Resource. N Engl J Med. 2015;372(23):2235-2242
    • (2015) N Engl J Med. , vol.372 , Issue.23 , pp. 2235-2242
    • Rehm, H.L.1    Berg, J.S.2    Brooks, L.D.3
  • 45
    • 84981252540 scopus 로고    scopus 로고
    • Accessed August 31
    • ClinGen EHR WG. http://clinicalgenome.org/about/working-groups/ehr/ Accessed August 31, 2015.
    • (2015)
  • 46
    • 84981202513 scopus 로고    scopus 로고
    • Genomic Medicine Meeting VII: Genomic Clinical Decision Support
    • Accessed August 28
    • NHGRI. Genomic Medicine Meeting VII: Genomic Clinical Decision Support: Developing Solutions for Clinical and Research Implementation. https:// www.genome.gov/27558904. Accessed August 28, 2015.
    • (2015) Developing Solutions for Clinical and Research Implementation
  • 48
    • 84981213302 scopus 로고    scopus 로고
    • Accessed August 28
    • National Academy of Medicine. IOM Use Models Pharmacogenomic Use Pilot for TPMT (Thiopurine) and CYP2C19 (Plavix) http://iom.nationalacademies.org/ ~/media/Files/Activity%20Files/Research/GenomicBasedResearch/Action% 20Collaboratives/Pharmacogenetics%20Standards%20Model.pdf?la�en. Accessed August 28, 2015.
    • (2015) IOM Use Models Pharmacogenomic Use Pilot for TPMT (Thiopurine) and CYP2C19 (Plavix)


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