-
1
-
-
0034736577
-
The human cytochrome P450 3A locus Gene evolution by capture of downstream exons
-
Finta C, & Zaphiropoulos P.G. The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons. Gene. 260, 13-23 (2000).
-
(2000)
Gene
, vol.260
, pp. 13-23
-
-
Finta, C.1
Zaphiropoulos, P.G.2
-
2
-
-
0035071598
-
Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
-
Kuehl P, et al. Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. Nat. Genet. 27, 383-391 (2001).
-
(2001)
Nat. Genet
, vol.27
, pp. 383-391
-
-
Kuehl, P.1
-
3
-
-
0036790299
-
CYP3A5 variant allele frequencies in Dutch caucasians
-
van Schaik R.H, van der Heiden I.P, van den Anker J.N, & Lindemans J. CYP3A5 variant allele frequencies in Dutch caucasians. Clin. Chem. 48, 1668-1671 (2002).
-
(2002)
Clin. Chem
, vol.48
, pp. 1668-1671
-
-
Van Schaik, R.H.1
Van Der Heiden, I.P.2
Van Den Anker, J.N.3
Lindemans, J.4
-
4
-
-
8844271778
-
CYP3A variation, and the evolution of salt-sensitivity variants
-
Thompson E.E, Kuttab-Boulos H, Witonsky D, Yang L, Roe B.A, & Di Rienzo A. CYP3A variation, and the evolution of salt-sensitivity variants. Am. J. Hum. Genet. 75, 1059-1069 (2004).
-
(2004)
Am. J. Hum. Genet
, vol.75
, pp. 1059-1069
-
-
Thompson, E.E.1
Kuttab-Boulos, H.2
Witonsky, D.3
Yang, L.4
Roe, B.A.5
Di Rienzo, A.6
-
5
-
-
40649113112
-
The role of tacrolimus in renal transplantation
-
Bowman L.J, & Brennan D.C. The role of tacrolimus in renal transplantation. Expert Opin. Pharmacother. 9, 635-643 (2008).
-
(2008)
Expert Opin. Pharmacother
, vol.9
, pp. 635-643
-
-
Bowman, L.J.1
Brennan, D.C.2
-
6
-
-
0029849460
-
Relationship of FK506 whole blood concentrations, and efficacy, and toxicity after liver, and kidney transplantation
-
Kershner R.P, & Fitzsimmons W.E. Relationship of FK506 whole blood concentrations, and efficacy, and toxicity after liver, and kidney transplantation. Transplantation. 62, 920-926 (1996).
-
(1996)
Transplantation
, vol.62
, pp. 920-926
-
-
Kershner, R.P.1
Fitzsimmons, W.E.2
-
7
-
-
65349115890
-
Opportunities to optimize tacrolimus therapy in solid organ transplantation: Report of the European consensus conference
-
Wallemacq P, et al. Opportunities to optimize tacrolimus therapy in solid organ transplantation: report of the European consensus conference. Ther. Drug Monit. 31, 139-152 (2009).
-
(2009)
Ther. Drug Monit
, vol.31
, pp. 139-152
-
-
Wallemacq, P.1
-
8
-
-
0035993769
-
Pharmacokinetics of tacrolimus in heart transplantation
-
European Tacrolimus Heart Study Group
-
Undre N.A, & Stevenson P.J. European Tacrolimus Heart Study Group. Pharmacokinetics of tacrolimus in heart transplantation. Transplant. Proc. 34, 1836-1838 (2002).
-
(2002)
Transplant. Proc
, vol.34
, pp. 1836-1838
-
-
Undre, N.A.1
Stevenson, P.J.2
-
9
-
-
0035993629
-
Therapeutic drug monitoring of tacrolimus early after liver transplantation
-
Braun F, et al. Therapeutic drug monitoring of tacrolimus early after liver transplantation. Transplant. Proc. 34, 1538-1539 (2002).
-
(2002)
Transplant. Proc
, vol.34
, pp. 1538-1539
-
-
Braun, F.1
-
10
-
-
37349034394
-
Reduced exposure to calcineurin inhibitors in renal transplantation
-
Ekberg H, et al. Reduced exposure to calcineurin inhibitors in renal transplantation. N. Engl. J. Med. 357, 2562-2575 (2007).
-
(2007)
N. Engl. J. Med
, vol.357
, pp. 2562-2575
-
-
Ekberg, H.1
-
11
-
-
84876946722
-
Tacrolimus predose concentrations do not predict the risk of acute rejection after renal transplantation: A pooled analysis from three randomized-controlled clinical trials
-
Bouamar R, et al. Tacrolimus predose concentrations do not predict the risk of acute rejection after renal transplantation: a pooled analysis from three randomized-controlled clinical trials. Am. J. Transplant. 13, 1253-1261 (2013).
-
(2013)
Am J. Transplant
, vol.13
, pp. 1253-1261
-
-
Bouamar, R.1
-
12
-
-
12144286933
-
The effect of CYP3A5, and MDR1 (ABCB1) polymorphisms on cyclosporine, and tacrolimus dose requirements and trough blood levels in stable renal transplant patients
-
Haufroid V, et al. The effect of CYP3A5, and MDR1 (ABCB1) polymorphisms on cyclosporine, and tacrolimus dose requirements and trough blood levels in stable renal transplant patients. Pharmacogenetics. 14, 147-154 (2004).
-
(2004)
Pharmacogenetics
, vol.14
, pp. 147-154
-
-
Haufroid, V.1
-
13
-
-
80052923257
-
Pharmacogenetics of calcineurin inhibitors in Brazilian renal transplant patients
-
Santoro A, et al. Pharmacogenetics of calcineurin inhibitors in Brazilian renal transplant patients. Pharmacogenomics. 12, 1293-1303 (2011).
-
(2011)
Pharmacogenomics
, vol.12
, pp. 1293-1303
-
-
Santoro, A.1
-
14
-
-
84869501187
-
Measurement, and compartmental modeling of the effect of CYP3A5 gene variation on systemic, and intrarenal tacrolimus disposition
-
Zheng S, et al. Measurement, and compartmental modeling of the effect of CYP3A5 gene variation on systemic, and intrarenal tacrolimus disposition. Clin. Pharmacol. Ther. 92, 737-745 (2012).
-
(2012)
Clin. Pharmacol. Ther
, vol.92
, pp. 737-745
-
-
Zheng, S.1
-
15
-
-
0035011155
-
Influence of cyclosporin, tacrolimus, and rapamycin on renal function, and arterial hypertension after renal transplantation
-
Morales J.M, Andres A, Rengel M, & Rodicio J.L. Influence of cyclosporin, tacrolimus, and rapamycin on renal function, and arterial hypertension after renal transplantation. Nephrol. Dial. Transplant. 16 (suppl. 1), 121-124 (2001).
-
(2001)
Nephrol. Dial. Transplant
, vol.16
, pp. 121-124
-
-
Morales, J.M.1
Andres, A.2
Rengel, M.3
Rodicio, J.L.4
-
16
-
-
0344666767
-
The natural history of chronic allograft nephropathy
-
Nankivell B.J, Borrows R.J, Fung C.L, O?Connell P.J, Allen R.D, & Chapman J.R. The natural history of chronic allograft nephropathy. N. Engl. J. Med. 349, 2326-2333 (2003).
-
(2003)
N. Engl. J. Med
, vol.349
, pp. 2326-2333
-
-
Nankivell, B.J.1
Borrows, R.J.2
Fung, C.L.3
Oconnell, P.J.4
Allen, R.D.5
Chapman, J.R.6
-
17
-
-
77952585319
-
Optimization of initial tacrolimus dose using pharmacogenetic testing
-
Thervet E, et al. Optimization of initial tacrolimus dose using pharmacogenetic testing. Clin. Pharmacol. Ther. 87, 721-726 (2010).
-
(2010)
Clin. Pharmacol. Ther
, vol.87
, pp. 721-726
-
-
Thervet, E.1
-
18
-
-
84921834006
-
Effect of CYP3A5 3 on kidney transplant recipients treated with tacrolimus: A systematic review, and meta-Analysis of observational studies
-
Rojas L, et al. Effect of CYP3A5.3 on kidney transplant recipients treated with tacrolimus: a systematic review, and meta-Analysis of observational studies. Pharmacogenomics J. 15, 38-48 (2015).
-
(2015)
Pharmacogenomics J.
, vol.15
, pp. 38-48
-
-
Rojas, L.1
-
19
-
-
42149176588
-
Impact of MDR1, and CYP3A5 on the oral clearance of tacrolimus, and tacrolimus-related renal dysfunction in adult livingdonor liver transplant patients
-
Fukudo M, et al. Impact of MDR1, and CYP3A5 on the oral clearance of tacrolimus, and tacrolimus-related renal dysfunction in adult livingdonor liver transplant patients. Pharmacogenet. Genomics. 18, 413-423 (2008).
-
(2008)
Pharmacogenet. Genomics
, vol.18
, pp. 413-423
-
-
Fukudo, M.1
-
20
-
-
34347354233
-
Polymorphisms of tumor necrosis factor-Alpha, interleukin-10, cytochrome P450 3A5, and ABCB1 in Chinese liver transplant patients treated with immunosuppressant tacrolimus
-
Li D, Zhu J.Y, Gao J, Wang X, Lou Y.Q, & Zhang G.L. Polymorphisms of tumor necrosis factor-Alpha, interleukin-10, cytochrome P450 3A5, and ABCB1 in Chinese liver transplant patients treated with immunosuppressant tacrolimus. Clin. Chim. Acta. 383, 133-139 (2007).
-
(2007)
Clin. Chim. Acta
, vol.383
, pp. 133-139
-
-
Li, D.1
Zhu, J.Y.2
Gao, J.3
Wang, X.4
Lou, Y.Q.5
Zhang, G.L.6
-
21
-
-
84855502073
-
Impact of CYP3A5 genotype of recipients as well as donors on the tacrolimus pharmacokinetics, and infectious complications after living-donor liver transplantation for Japanese adult recipients
-
Muraki Y, et al. Impact of CYP3A5 genotype of recipients as well as donors on the tacrolimus pharmacokinetics, and infectious complications after living-donor liver transplantation for Japanese adult recipients. Ann. Transplant. 16, 55-62 (2011).
-
(2011)
Ann. Transplant
, vol.16
, pp. 55-62
-
-
Muraki, Y.1
-
22
-
-
33646439263
-
Tacrolimus dose requirement in relation to donor and recipient ABCB1, and CYP3A5 gene polymorphisms in Chinese liver transplant patients
-
Wei-lin W, et al. Tacrolimus dose requirement in relation to donor and recipient ABCB1, and CYP3A5 gene polymorphisms in Chinese liver transplant patients. Liver Transpl. 12, 775-780 (2006).
-
(2006)
Liver Transpl
, vol.12
, pp. 775-780
-
-
Wei-Lin, W.1
-
23
-
-
31044454408
-
Influence of CYP3A5 gene polymorphisms of donor rather than recipient to tacrolimus individual dose requirement in liver transplantation
-
Yu S, et al. Influence of CYP3A5 gene polymorphisms of donor rather than recipient to tacrolimus individual dose requirement in liver transplantation. Transplantation. 81, 46-51 (2006).
-
(2006)
Transplantation
, vol.81
, pp. 46-51
-
-
Yu, S.1
-
24
-
-
84868196047
-
Combinational effect of intestinal, and hepatic CYP3A5 genotypes on tacrolimus pharmacokinetics in recipients of living donor liver transplantation
-
Ji E, Choi L, Suh K.S, Cho J.Y, Han N, & Oh J.M. Combinational effect of intestinal, and hepatic CYP3A5 genotypes on tacrolimus pharmacokinetics in recipients of living donor liver transplantation. Transplantation. 94, 866-872 (2012).
-
(2012)
Transplantation
, vol.94
, pp. 866-872
-
-
Ji, E.1
Choi, L.2
Suh, K.S.3
Cho, J.Y.4
Han, N.5
Oh, J.M.6
-
25
-
-
0037693831
-
Tacrolimus dosing in pediatric heart transplant patients is related to CYP3A5, and MDR1 gene polymorphisms
-
Zheng H, et al. Tacrolimus dosing in pediatric heart transplant patients is related to CYP3A5, and MDR1 gene polymorphisms. Am. J. Transplant. 3, 477-483 (2003).
-
(2003)
Am. J. Transplant
, vol.3
, pp. 477-483
-
-
Zheng, H.1
-
26
-
-
80655147017
-
Age, and CYP3A5 genotype affect tacrolimus dosing requirements after transplant in pediatric heart recipients
-
Gijsen V, et al. Age, and CYP3A5 genotype affect tacrolimus dosing requirements after transplant in pediatric heart recipients. J. Heart Lung Transplant. 30, 1352-1359 (2011).
-
(2011)
J. Heart Lung Transplant
, vol.30
, pp. 1352-1359
-
-
Gijsen, V.1
-
27
-
-
84906538104
-
Influence of donor-recipient CYP3A4/5 genotypes, age, and fluconazole on tacrolimus pharmacokinetics in pediatric liver transplantation: A population approach
-
Guy-Viterbo V, et al. Influence of donor-recipient CYP3A4/5 genotypes, age, and fluconazole on tacrolimus pharmacokinetics in pediatric liver transplantation: a population approach. Pharmacogenomics. 15, 1207-1221 (2014).
-
(2014)
Pharmacogenomics
, vol.15
, pp. 1207-1221
-
-
Guy-Viterbo, V.1
-
28
-
-
34147109227
-
Influence of the CYP3A5 genotype on tacrolimus pharmacokinetics, and pharmacodynamics in young kidney transplant recipients
-
Ferraresso M, et al. Influence of the CYP3A5 genotype on tacrolimus pharmacokinetics, and pharmacodynamics in young kidney transplant recipients. Pediatr. Transplant. 11, 296-300 (2007).
-
(2007)
Pediatr. Transplant
, vol.11
, pp. 296-300
-
-
Ferraresso, M.1
-
29
-
-
70450253289
-
Population pharmacokinetics, and pharmacogenetics of tacrolimus in de novo pediatric kidney transplant recipients
-
Zhao W, et al. Population pharmacokinetics, and pharmacogenetics of tacrolimus in de novo pediatric kidney transplant recipients. Clin. Pharmacol. Ther. 86, 609-618 (2009).
-
(2009)
Clin. Pharmacol. Ther
, vol.86
, pp. 609-618
-
-
Zhao, W.1
-
30
-
-
79960579542
-
Influence of CYP3A5 polymorphism on tacrolimus maintenance doses, and serum levels after renal transplantation: Age dependency, and pharmacological interaction with steroids
-
Ferraris J.R, et al. Influence of CYP3A5 polymorphism on tacrolimus maintenance doses, and serum levels after renal transplantation: age dependency, and pharmacological interaction with steroids. Pediatr. Transplant. 15, 525-532 (2011).
-
(2011)
Pediatr. Transplant
, vol.15
, pp. 525-532
-
-
Ferraris, J.R.1
-
31
-
-
82455187996
-
The interactions of age, genetics, and disease severity on tacrolimus dosing requirements after pediatric kidney and liver transplantation
-
de Wildt S.N, et al. The interactions of age, genetics, and disease severity on tacrolimus dosing requirements after pediatric kidney and liver transplantation. Eur. J. Clin. Pharmacol. 67, 1231-1241 (2011).
-
(2011)
Eur. J. Clin. Pharmacol
, vol.67
, pp. 1231-1241
-
-
De Wildt, S.N.1
-
32
-
-
84864109520
-
CYP3A5 polymorphism in Mexican renal transplant recipients, and its association with tacrolimus dosing
-
García-Roca P, et al. CYP3A5 polymorphism in Mexican renal transplant recipients, and its association with tacrolimus dosing. Arch. Med. Res. 43, 283-287 (2012).
-
(2012)
Arch. Med. Res
, vol.43
, pp. 283-287
-
-
García-Roca, P.1
-
33
-
-
84930240506
-
Effect of CYP3A5 genotype, steroids, and azoles on tacrolimus in a pediatric renal transplant population
-
Lalan S, et al. Effect of CYP3A5 genotype, steroids, and azoles on tacrolimus in a pediatric renal transplant population. Pediatr. Nephrol. 29, 2039-2049 (2014).
-
(2014)
Pediatr. Nephrol
, vol.29
, pp. 2039-2049
-
-
Lalan, S.1
-
34
-
-
42549152343
-
Standard dosing of tacrolimus leads to overexposure in pediatric renal transplantation recipients
-
Kausman J.Y, Patel B, & Marks S.D. Standard dosing of tacrolimus leads to overexposure in pediatric renal transplantation recipients. Pediatr. Transplant. 12, 329-335 (2008).
-
(2008)
Pediatr. Transplant
, vol.12
, pp. 329-335
-
-
Kausman, J.Y.1
Patel, B.2
Marks, S.D.3
-
35
-
-
53549126614
-
Effects of CYP3A5, and MDR1 single nucleotide polymorphisms on drug interactions between tacrolimus, and fluconazole in renal allograft recipients
-
Kuypers D.R, de Jonge H, Naesens M, & Vanrenterghem Y. Effects of CYP3A5, and MDR1 single nucleotide polymorphisms on drug interactions between tacrolimus, and fluconazole in renal allograft recipients. Pharmacogenet. Genomics. 18, 861-868 (2008).
-
(2008)
Pharmacogenet. Genomics
, vol.18
, pp. 861-868
-
-
Kuypers, D.R.1
De Jonge, H.2
Naesens, M.3
Vanrenterghem, Y.4
-
36
-
-
70149105801
-
CYP3A5 1/ 3 genotype influences the blood concentration of tacrolimus in response to metabolic inhibition by ketoconazole
-
Chandel N, Aggarwal P.K, Minz M, Sakhuja V, Kohli K.K, & Jha V. CYP3A5 1/ 3 genotype influences the blood concentration of tacrolimus in response to metabolic inhibition by ketoconazole. Pharmacogenet. Genomics. 19, 458-463 (2009).
-
(2009)
Pharmacogenet. Genomics
, vol.19
, pp. 458-463
-
-
Chandel, N.1
Aggarwal, P.K.2
Minz, M.3
Sakhuja, V.4
Kohli, K.K.5
Jha, V.6
-
37
-
-
0036360906
-
Drug interactions with tacrolimus
-
van Gelder T. Drug interactions with tacrolimus. Drug Saf. 25, 707-712 (2002).
-
(2002)
Drug Saf
, vol.25
, pp. 707-712
-
-
Van Gelder, T.1
-
38
-
-
3242772986
-
Clinical pharmacokinetics and pharmacodynamics of tacrolimus in solid organ transplantation
-
Staatz C.E, & Tett S.E. Clinical pharmacokinetics and pharmacodynamics of tacrolimus in solid organ transplantation. Clin. Pharmacokinet. 43, 623-653 (2004).
-
(2004)
Clin. Pharmacokinet
, vol.43
, pp. 623-653
-
-
Staatz, C.E.1
Tett, S.E.2
-
39
-
-
84868621530
-
Donor ABCB1 variant associates with increased risk for kidney allograft failure
-
Moore J, et al. Donor ABCB1 variant associates with increased risk for kidney allograft failure. J. Am. Soc. Nephrol. 23, 1891-1899 (2012).
-
(2012)
J. Am. Soc. Nephrol
, vol.23
, pp. 1891-1899
-
-
Moore, J.1
-
40
-
-
14044278166
-
Tacrolimus pharmacogenetics: The CYP3A5 1 allele predicts low dose-normalized tacrolimus blood concentrations in whites, and South Asians
-
Macphee I.A, et al. Tacrolimus pharmacogenetics: the CYP3A5 1 allele predicts low dose-normalized tacrolimus blood concentrations in whites, and South Asians. Transplantation. 79, 499-502 (2005).
-
(2005)
Transplantation
, vol.79
, pp. 499-502
-
-
Macphee, I.A.1
|