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Volumn 98, Issue 1, 2015, Pages 19-24

Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for CYP3A5 genotype and tacrolimus dosing

(16)  Birdwell, K A a   Decker, B b   Barbarino, J M c   Peterson, J F a,d   Stein, C M a,e   Sadee, W f   Wang, D f   Vinks, A A g,h   He, Y i   Swen, J J j   Leeder, J S k   Van Schaik, R H N l   Thummel, K E m   Klein, T E c   Caudle, K E n   MacPhee, I A M o  


Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; INTERLEUKIN 2; TACROLIMUS; TRANSCRIPTION FACTOR NFAT; CYTOCHROME P450 3A; IMMUNOSUPPRESSIVE AGENT;

EID: 84962207669     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1002/cpt.113     Document Type: Article
Times cited : (529)

References (40)
  • 1
    • 0034736577 scopus 로고    scopus 로고
    • The human cytochrome P450 3A locus Gene evolution by capture of downstream exons
    • Finta C, & Zaphiropoulos P.G. The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons. Gene. 260, 13-23 (2000).
    • (2000) Gene , vol.260 , pp. 13-23
    • Finta, C.1    Zaphiropoulos, P.G.2
  • 2
    • 0035071598 scopus 로고    scopus 로고
    • Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
    • Kuehl P, et al. Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. Nat. Genet. 27, 383-391 (2001).
    • (2001) Nat. Genet , vol.27 , pp. 383-391
    • Kuehl, P.1
  • 5
    • 40649113112 scopus 로고    scopus 로고
    • The role of tacrolimus in renal transplantation
    • Bowman L.J, & Brennan D.C. The role of tacrolimus in renal transplantation. Expert Opin. Pharmacother. 9, 635-643 (2008).
    • (2008) Expert Opin. Pharmacother , vol.9 , pp. 635-643
    • Bowman, L.J.1    Brennan, D.C.2
  • 6
    • 0029849460 scopus 로고    scopus 로고
    • Relationship of FK506 whole blood concentrations, and efficacy, and toxicity after liver, and kidney transplantation
    • Kershner R.P, & Fitzsimmons W.E. Relationship of FK506 whole blood concentrations, and efficacy, and toxicity after liver, and kidney transplantation. Transplantation. 62, 920-926 (1996).
    • (1996) Transplantation , vol.62 , pp. 920-926
    • Kershner, R.P.1    Fitzsimmons, W.E.2
  • 7
    • 65349115890 scopus 로고    scopus 로고
    • Opportunities to optimize tacrolimus therapy in solid organ transplantation: Report of the European consensus conference
    • Wallemacq P, et al. Opportunities to optimize tacrolimus therapy in solid organ transplantation: report of the European consensus conference. Ther. Drug Monit. 31, 139-152 (2009).
    • (2009) Ther. Drug Monit , vol.31 , pp. 139-152
    • Wallemacq, P.1
  • 8
    • 0035993769 scopus 로고    scopus 로고
    • Pharmacokinetics of tacrolimus in heart transplantation
    • European Tacrolimus Heart Study Group
    • Undre N.A, & Stevenson P.J. European Tacrolimus Heart Study Group. Pharmacokinetics of tacrolimus in heart transplantation. Transplant. Proc. 34, 1836-1838 (2002).
    • (2002) Transplant. Proc , vol.34 , pp. 1836-1838
    • Undre, N.A.1    Stevenson, P.J.2
  • 9
    • 0035993629 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of tacrolimus early after liver transplantation
    • Braun F, et al. Therapeutic drug monitoring of tacrolimus early after liver transplantation. Transplant. Proc. 34, 1538-1539 (2002).
    • (2002) Transplant. Proc , vol.34 , pp. 1538-1539
    • Braun, F.1
  • 10
    • 37349034394 scopus 로고    scopus 로고
    • Reduced exposure to calcineurin inhibitors in renal transplantation
    • Ekberg H, et al. Reduced exposure to calcineurin inhibitors in renal transplantation. N. Engl. J. Med. 357, 2562-2575 (2007).
    • (2007) N. Engl. J. Med , vol.357 , pp. 2562-2575
    • Ekberg, H.1
  • 11
    • 84876946722 scopus 로고    scopus 로고
    • Tacrolimus predose concentrations do not predict the risk of acute rejection after renal transplantation: A pooled analysis from three randomized-controlled clinical trials
    • Bouamar R, et al. Tacrolimus predose concentrations do not predict the risk of acute rejection after renal transplantation: a pooled analysis from three randomized-controlled clinical trials. Am. J. Transplant. 13, 1253-1261 (2013).
    • (2013) Am J. Transplant , vol.13 , pp. 1253-1261
    • Bouamar, R.1
  • 12
    • 12144286933 scopus 로고    scopus 로고
    • The effect of CYP3A5, and MDR1 (ABCB1) polymorphisms on cyclosporine, and tacrolimus dose requirements and trough blood levels in stable renal transplant patients
    • Haufroid V, et al. The effect of CYP3A5, and MDR1 (ABCB1) polymorphisms on cyclosporine, and tacrolimus dose requirements and trough blood levels in stable renal transplant patients. Pharmacogenetics. 14, 147-154 (2004).
    • (2004) Pharmacogenetics , vol.14 , pp. 147-154
    • Haufroid, V.1
  • 13
    • 80052923257 scopus 로고    scopus 로고
    • Pharmacogenetics of calcineurin inhibitors in Brazilian renal transplant patients
    • Santoro A, et al. Pharmacogenetics of calcineurin inhibitors in Brazilian renal transplant patients. Pharmacogenomics. 12, 1293-1303 (2011).
    • (2011) Pharmacogenomics , vol.12 , pp. 1293-1303
    • Santoro, A.1
  • 14
    • 84869501187 scopus 로고    scopus 로고
    • Measurement, and compartmental modeling of the effect of CYP3A5 gene variation on systemic, and intrarenal tacrolimus disposition
    • Zheng S, et al. Measurement, and compartmental modeling of the effect of CYP3A5 gene variation on systemic, and intrarenal tacrolimus disposition. Clin. Pharmacol. Ther. 92, 737-745 (2012).
    • (2012) Clin. Pharmacol. Ther , vol.92 , pp. 737-745
    • Zheng, S.1
  • 15
    • 0035011155 scopus 로고    scopus 로고
    • Influence of cyclosporin, tacrolimus, and rapamycin on renal function, and arterial hypertension after renal transplantation
    • Morales J.M, Andres A, Rengel M, & Rodicio J.L. Influence of cyclosporin, tacrolimus, and rapamycin on renal function, and arterial hypertension after renal transplantation. Nephrol. Dial. Transplant. 16 (suppl. 1), 121-124 (2001).
    • (2001) Nephrol. Dial. Transplant , vol.16 , pp. 121-124
    • Morales, J.M.1    Andres, A.2    Rengel, M.3    Rodicio, J.L.4
  • 17
    • 77952585319 scopus 로고    scopus 로고
    • Optimization of initial tacrolimus dose using pharmacogenetic testing
    • Thervet E, et al. Optimization of initial tacrolimus dose using pharmacogenetic testing. Clin. Pharmacol. Ther. 87, 721-726 (2010).
    • (2010) Clin. Pharmacol. Ther , vol.87 , pp. 721-726
    • Thervet, E.1
  • 18
    • 84921834006 scopus 로고    scopus 로고
    • Effect of CYP3A5 3 on kidney transplant recipients treated with tacrolimus: A systematic review, and meta-Analysis of observational studies
    • Rojas L, et al. Effect of CYP3A5.3 on kidney transplant recipients treated with tacrolimus: a systematic review, and meta-Analysis of observational studies. Pharmacogenomics J. 15, 38-48 (2015).
    • (2015) Pharmacogenomics J. , vol.15 , pp. 38-48
    • Rojas, L.1
  • 19
    • 42149176588 scopus 로고    scopus 로고
    • Impact of MDR1, and CYP3A5 on the oral clearance of tacrolimus, and tacrolimus-related renal dysfunction in adult livingdonor liver transplant patients
    • Fukudo M, et al. Impact of MDR1, and CYP3A5 on the oral clearance of tacrolimus, and tacrolimus-related renal dysfunction in adult livingdonor liver transplant patients. Pharmacogenet. Genomics. 18, 413-423 (2008).
    • (2008) Pharmacogenet. Genomics , vol.18 , pp. 413-423
    • Fukudo, M.1
  • 20
    • 34347354233 scopus 로고    scopus 로고
    • Polymorphisms of tumor necrosis factor-Alpha, interleukin-10, cytochrome P450 3A5, and ABCB1 in Chinese liver transplant patients treated with immunosuppressant tacrolimus
    • Li D, Zhu J.Y, Gao J, Wang X, Lou Y.Q, & Zhang G.L. Polymorphisms of tumor necrosis factor-Alpha, interleukin-10, cytochrome P450 3A5, and ABCB1 in Chinese liver transplant patients treated with immunosuppressant tacrolimus. Clin. Chim. Acta. 383, 133-139 (2007).
    • (2007) Clin. Chim. Acta , vol.383 , pp. 133-139
    • Li, D.1    Zhu, J.Y.2    Gao, J.3    Wang, X.4    Lou, Y.Q.5    Zhang, G.L.6
  • 21
    • 84855502073 scopus 로고    scopus 로고
    • Impact of CYP3A5 genotype of recipients as well as donors on the tacrolimus pharmacokinetics, and infectious complications after living-donor liver transplantation for Japanese adult recipients
    • Muraki Y, et al. Impact of CYP3A5 genotype of recipients as well as donors on the tacrolimus pharmacokinetics, and infectious complications after living-donor liver transplantation for Japanese adult recipients. Ann. Transplant. 16, 55-62 (2011).
    • (2011) Ann. Transplant , vol.16 , pp. 55-62
    • Muraki, Y.1
  • 22
    • 33646439263 scopus 로고    scopus 로고
    • Tacrolimus dose requirement in relation to donor and recipient ABCB1, and CYP3A5 gene polymorphisms in Chinese liver transplant patients
    • Wei-lin W, et al. Tacrolimus dose requirement in relation to donor and recipient ABCB1, and CYP3A5 gene polymorphisms in Chinese liver transplant patients. Liver Transpl. 12, 775-780 (2006).
    • (2006) Liver Transpl , vol.12 , pp. 775-780
    • Wei-Lin, W.1
  • 23
    • 31044454408 scopus 로고    scopus 로고
    • Influence of CYP3A5 gene polymorphisms of donor rather than recipient to tacrolimus individual dose requirement in liver transplantation
    • Yu S, et al. Influence of CYP3A5 gene polymorphisms of donor rather than recipient to tacrolimus individual dose requirement in liver transplantation. Transplantation. 81, 46-51 (2006).
    • (2006) Transplantation , vol.81 , pp. 46-51
    • Yu, S.1
  • 24
    • 84868196047 scopus 로고    scopus 로고
    • Combinational effect of intestinal, and hepatic CYP3A5 genotypes on tacrolimus pharmacokinetics in recipients of living donor liver transplantation
    • Ji E, Choi L, Suh K.S, Cho J.Y, Han N, & Oh J.M. Combinational effect of intestinal, and hepatic CYP3A5 genotypes on tacrolimus pharmacokinetics in recipients of living donor liver transplantation. Transplantation. 94, 866-872 (2012).
    • (2012) Transplantation , vol.94 , pp. 866-872
    • Ji, E.1    Choi, L.2    Suh, K.S.3    Cho, J.Y.4    Han, N.5    Oh, J.M.6
  • 25
    • 0037693831 scopus 로고    scopus 로고
    • Tacrolimus dosing in pediatric heart transplant patients is related to CYP3A5, and MDR1 gene polymorphisms
    • Zheng H, et al. Tacrolimus dosing in pediatric heart transplant patients is related to CYP3A5, and MDR1 gene polymorphisms. Am. J. Transplant. 3, 477-483 (2003).
    • (2003) Am. J. Transplant , vol.3 , pp. 477-483
    • Zheng, H.1
  • 26
    • 80655147017 scopus 로고    scopus 로고
    • Age, and CYP3A5 genotype affect tacrolimus dosing requirements after transplant in pediatric heart recipients
    • Gijsen V, et al. Age, and CYP3A5 genotype affect tacrolimus dosing requirements after transplant in pediatric heart recipients. J. Heart Lung Transplant. 30, 1352-1359 (2011).
    • (2011) J. Heart Lung Transplant , vol.30 , pp. 1352-1359
    • Gijsen, V.1
  • 27
    • 84906538104 scopus 로고    scopus 로고
    • Influence of donor-recipient CYP3A4/5 genotypes, age, and fluconazole on tacrolimus pharmacokinetics in pediatric liver transplantation: A population approach
    • Guy-Viterbo V, et al. Influence of donor-recipient CYP3A4/5 genotypes, age, and fluconazole on tacrolimus pharmacokinetics in pediatric liver transplantation: a population approach. Pharmacogenomics. 15, 1207-1221 (2014).
    • (2014) Pharmacogenomics , vol.15 , pp. 1207-1221
    • Guy-Viterbo, V.1
  • 28
    • 34147109227 scopus 로고    scopus 로고
    • Influence of the CYP3A5 genotype on tacrolimus pharmacokinetics, and pharmacodynamics in young kidney transplant recipients
    • Ferraresso M, et al. Influence of the CYP3A5 genotype on tacrolimus pharmacokinetics, and pharmacodynamics in young kidney transplant recipients. Pediatr. Transplant. 11, 296-300 (2007).
    • (2007) Pediatr. Transplant , vol.11 , pp. 296-300
    • Ferraresso, M.1
  • 29
    • 70450253289 scopus 로고    scopus 로고
    • Population pharmacokinetics, and pharmacogenetics of tacrolimus in de novo pediatric kidney transplant recipients
    • Zhao W, et al. Population pharmacokinetics, and pharmacogenetics of tacrolimus in de novo pediatric kidney transplant recipients. Clin. Pharmacol. Ther. 86, 609-618 (2009).
    • (2009) Clin. Pharmacol. Ther , vol.86 , pp. 609-618
    • Zhao, W.1
  • 30
    • 79960579542 scopus 로고    scopus 로고
    • Influence of CYP3A5 polymorphism on tacrolimus maintenance doses, and serum levels after renal transplantation: Age dependency, and pharmacological interaction with steroids
    • Ferraris J.R, et al. Influence of CYP3A5 polymorphism on tacrolimus maintenance doses, and serum levels after renal transplantation: age dependency, and pharmacological interaction with steroids. Pediatr. Transplant. 15, 525-532 (2011).
    • (2011) Pediatr. Transplant , vol.15 , pp. 525-532
    • Ferraris, J.R.1
  • 31
    • 82455187996 scopus 로고    scopus 로고
    • The interactions of age, genetics, and disease severity on tacrolimus dosing requirements after pediatric kidney and liver transplantation
    • de Wildt S.N, et al. The interactions of age, genetics, and disease severity on tacrolimus dosing requirements after pediatric kidney and liver transplantation. Eur. J. Clin. Pharmacol. 67, 1231-1241 (2011).
    • (2011) Eur. J. Clin. Pharmacol , vol.67 , pp. 1231-1241
    • De Wildt, S.N.1
  • 32
    • 84864109520 scopus 로고    scopus 로고
    • CYP3A5 polymorphism in Mexican renal transplant recipients, and its association with tacrolimus dosing
    • García-Roca P, et al. CYP3A5 polymorphism in Mexican renal transplant recipients, and its association with tacrolimus dosing. Arch. Med. Res. 43, 283-287 (2012).
    • (2012) Arch. Med. Res , vol.43 , pp. 283-287
    • García-Roca, P.1
  • 33
    • 84930240506 scopus 로고    scopus 로고
    • Effect of CYP3A5 genotype, steroids, and azoles on tacrolimus in a pediatric renal transplant population
    • Lalan S, et al. Effect of CYP3A5 genotype, steroids, and azoles on tacrolimus in a pediatric renal transplant population. Pediatr. Nephrol. 29, 2039-2049 (2014).
    • (2014) Pediatr. Nephrol , vol.29 , pp. 2039-2049
    • Lalan, S.1
  • 34
    • 42549152343 scopus 로고    scopus 로고
    • Standard dosing of tacrolimus leads to overexposure in pediatric renal transplantation recipients
    • Kausman J.Y, Patel B, & Marks S.D. Standard dosing of tacrolimus leads to overexposure in pediatric renal transplantation recipients. Pediatr. Transplant. 12, 329-335 (2008).
    • (2008) Pediatr. Transplant , vol.12 , pp. 329-335
    • Kausman, J.Y.1    Patel, B.2    Marks, S.D.3
  • 35
    • 53549126614 scopus 로고    scopus 로고
    • Effects of CYP3A5, and MDR1 single nucleotide polymorphisms on drug interactions between tacrolimus, and fluconazole in renal allograft recipients
    • Kuypers D.R, de Jonge H, Naesens M, & Vanrenterghem Y. Effects of CYP3A5, and MDR1 single nucleotide polymorphisms on drug interactions between tacrolimus, and fluconazole in renal allograft recipients. Pharmacogenet. Genomics. 18, 861-868 (2008).
    • (2008) Pharmacogenet. Genomics , vol.18 , pp. 861-868
    • Kuypers, D.R.1    De Jonge, H.2    Naesens, M.3    Vanrenterghem, Y.4
  • 36
    • 70149105801 scopus 로고    scopus 로고
    • CYP3A5 1/ 3 genotype influences the blood concentration of tacrolimus in response to metabolic inhibition by ketoconazole
    • Chandel N, Aggarwal P.K, Minz M, Sakhuja V, Kohli K.K, & Jha V. CYP3A5 1/ 3 genotype influences the blood concentration of tacrolimus in response to metabolic inhibition by ketoconazole. Pharmacogenet. Genomics. 19, 458-463 (2009).
    • (2009) Pharmacogenet. Genomics , vol.19 , pp. 458-463
    • Chandel, N.1    Aggarwal, P.K.2    Minz, M.3    Sakhuja, V.4    Kohli, K.K.5    Jha, V.6
  • 37
    • 0036360906 scopus 로고    scopus 로고
    • Drug interactions with tacrolimus
    • van Gelder T. Drug interactions with tacrolimus. Drug Saf. 25, 707-712 (2002).
    • (2002) Drug Saf , vol.25 , pp. 707-712
    • Van Gelder, T.1
  • 38
    • 3242772986 scopus 로고    scopus 로고
    • Clinical pharmacokinetics and pharmacodynamics of tacrolimus in solid organ transplantation
    • Staatz C.E, & Tett S.E. Clinical pharmacokinetics and pharmacodynamics of tacrolimus in solid organ transplantation. Clin. Pharmacokinet. 43, 623-653 (2004).
    • (2004) Clin. Pharmacokinet , vol.43 , pp. 623-653
    • Staatz, C.E.1    Tett, S.E.2
  • 39
    • 84868621530 scopus 로고    scopus 로고
    • Donor ABCB1 variant associates with increased risk for kidney allograft failure
    • Moore J, et al. Donor ABCB1 variant associates with increased risk for kidney allograft failure. J. Am. Soc. Nephrol. 23, 1891-1899 (2012).
    • (2012) J. Am. Soc. Nephrol , vol.23 , pp. 1891-1899
    • Moore, J.1
  • 40
    • 14044278166 scopus 로고    scopus 로고
    • Tacrolimus pharmacogenetics: The CYP3A5 1 allele predicts low dose-normalized tacrolimus blood concentrations in whites, and South Asians
    • Macphee I.A, et al. Tacrolimus pharmacogenetics: the CYP3A5 1 allele predicts low dose-normalized tacrolimus blood concentrations in whites, and South Asians. Transplantation. 79, 499-502 (2005).
    • (2005) Transplantation , vol.79 , pp. 499-502
    • Macphee, I.A.1


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