-
2
-
-
46449115901
-
-
E. M. Driggers, S. P. Hale, J. Lee, N. K. Terrett, Nat. Rev. Drug Discovery 2008, 7, 608;
-
(2008)
Nat. Rev. Drug Discovery
, vol.7
, pp. 608
-
-
Driggers, E.M.1
Hale, S.P.2
Lee, J.3
Terrett, N.K.4
-
3
-
-
84906307859
-
-
E. A. Villar, D. Beglov, S. Chennamadhavuni, J. A. Porco Jr, D. Kozakov, S. Vajda, A. Whitty, Nat. Chem. Biol. 2014, 10, 723.
-
(2014)
Nat. Chem. Biol.
, vol.10
, pp. 723
-
-
Villar, E.A.1
Beglov, D.2
Chennamadhavuni, S.3
Porco, J.A.4
Kozakov, D.5
Vajda, S.6
Whitty, A.7
-
6
-
-
84865676018
-
-
K. M. G. O'Connell, H. S. G. Beckmann, L. Laraia, H. T. Horsley, A. Bender, A. R. Venkitaraman, D. R. Spring, Org. Biomol. Chem. 2012, 10, 7545.
-
(2012)
Org. Biomol. Chem.
, vol.10
, pp. 7545
-
-
O'Connell, K.M.G.1
Beckmann, H.S.G.2
Laraia, L.3
Horsley, H.T.4
Bender, A.5
Venkitaraman, A.R.6
Spring, D.R.7
-
7
-
-
0032572123
-
-
K. C. Nicolaou, J. Pastor, N. Winssinger, F. Murphy, J. Am. Chem. Soc. 1998, 120, 5132;
-
(1998)
J. Am. Chem. Soc.
, vol.120
, pp. 5132
-
-
Nicolaou, K.C.1
Pastor, J.2
Winssinger, N.3
Murphy, F.4
-
8
-
-
0033579147
-
-
D. Lee, J. K. Sello, S. L. Schreiber, J. Am. Chem. Soc. 1999, 121, 10648;
-
(1999)
J. Am. Chem. Soc.
, vol.121
, pp. 10648
-
-
Lee, D.1
Sello, J.K.2
Schreiber, S.L.3
-
9
-
-
1842454311
-
-
D. R. Schmidt, O. Kwon, S. L. Schreiber, J. Comb. Chem. 2004, 6, 286;
-
(2004)
J. Comb. Chem.
, vol.6
, pp. 286
-
-
Schmidt, D.R.1
Kwon, O.2
Schreiber, S.L.3
-
10
-
-
0041317008
-
-
S. Bäurle, T. Blume, A. Mengel, C. Parchmann, W. Skuballa, S. Bäsler, M. Schäfer, D. Sülzle, H.-P. Wrona-Metzinger, Angew. Chem. Int. Ed. 2003, 42, 3961;
-
(2003)
Angew. Chem. Int. Ed.
, vol.42
, pp. 3961
-
-
Bäurle, S.1
Blume, T.2
Mengel, A.3
Parchmann, C.4
Skuballa, W.5
Bäsler, S.6
Schäfer, M.7
Sülzle, D.8
Wrona-Metzinger, H.-P.9
-
11
-
-
84990206571
-
-
Angew. Chem. 2003, 115, 4091;
-
(2003)
Angew. Chem.
, vol.115
, pp. 4091
-
-
-
13
-
-
0141630574
-
-
Q. Su, A. B. Beeler, E. Lobkovsky, J. A. Porco, Jr., J. S. Panek, Org. Lett. 2003, 5, 2149;
-
(2003)
Org. Lett.
, vol.5
, pp. 2149
-
-
Su, Q.1
Beeler, A.B.2
Lobkovsky, E.3
Porco, J.A.4
Panek, J.S.5
-
14
-
-
27744456130
-
-
A. B. Beeler, D. E. Acquilano, Q. Su, F. Yan, B. L. Roth, J. S. Panek, J. A. Porco, Jr., J. Comb. Chem. 2005, 7, 673.
-
(2005)
J. Comb. Chem.
, vol.7
, pp. 673
-
-
Beeler, A.B.1
Acquilano, D.E.2
Su, Q.3
Yan, F.4
Roth, B.L.5
Panek, J.S.6
Porco, J.A.7
-
15
-
-
84884837727
-
-
H. S. G. Beckmann, F. Nie, C. E. Hagerman, H. Johansson, Y. S. Tan, D. Wilcke, D. R. Spring, Nat. Chem. 2013, 5, 861.
-
(2013)
Nat. Chem.
, vol.5
, pp. 861
-
-
Beckmann, H.S.G.1
Nie, F.2
Hagerman, C.E.3
Johansson, H.4
Tan, Y.S.5
Wilcke, D.6
Spring, D.R.7
-
16
-
-
84880296641
-
-
W. R. J. D. Galloway, A. Isidro-Llobet, D. R. Spring, Nat. Commun. 2010, 1, 80, DOI: 10.1038/ncomms1081.
-
(2010)
Nat. Commun.
, vol.1
, pp. 80
-
-
Galloway, W.R.J.D.1
Isidro-Llobet, A.2
Spring, D.R.3
-
19
-
-
84926341917
-
-
A. Isidro-Llobet, K. Hadje Georgiou, W. R. J. D. Galloway, E. Giacomini, M. Hansen, G. Mendez-Abt, Y. S. Tan, L. Carro-Santos, H. F. Sore, D. R. Spring, Org. Biomol. Chem. 2015, 13, 4570.
-
(2015)
Org. Biomol. Chem.
, vol.13
, pp. 4570
-
-
Isidro-Llobet, A.1
Georgiou, K.H.2
Galloway, W.R.J.D.3
Giacomini, E.4
Hansen, M.5
Mendez-Abt, G.6
Tan, Y.S.7
Carro-Santos, L.8
Sore, H.F.9
Spring, D.R.10
-
21
-
-
82955213501
-
-
M. Dow, M. Fisher, T. James, F. Marchetti, A. Nelson, Org. Biomol. Chem. 2012, 10, 17;
-
(2012)
Org. Biomol. Chem.
, vol.10
, pp. 17
-
-
Dow, M.1
Fisher, M.2
James, T.3
Marchetti, F.4
Nelson, A.5
-
22
-
-
84911942058
-
-
E. Lenci, A. Guarna, A. Trabocchi, Molecules 2014, 19, 16506;
-
(2014)
Molecules
, vol.19
, pp. 16506
-
-
Lenci, E.1
Guarna, A.2
Trabocchi, A.3
-
24
-
-
84858704374
-
-
F. Kopp, C. F. Stratton, L. B. Akella, D. S. Tan, Nat. Chem. Biol. 2012, 8, 358;
-
(2012)
Nat. Chem. Biol.
, vol.8
, pp. 358
-
-
Kopp, F.1
Stratton, C.F.2
Akella, L.B.3
Tan, D.S.4
-
25
-
-
84871342809
-
-
R. A. Bauer, T. A. Wenderski, D. S. Tan, Nat. Chem. Biol. 2013, 9, 21;
-
(2013)
Nat. Chem. Biol.
, vol.9
, pp. 21
-
-
Bauer, R.A.1
Wenderski, T.A.2
Tan, D.S.3
-
26
-
-
84955290294
-
-
C. Kitsiou, J. J. Hindes, P. I'Anson, P. Jackson, T. C. Wilson, E. K. Daly, H. R. Felstead, P. Hearnshaw, W. P. Unsworth, Angew. Chem. Int. Ed. 2015, 54, 15794;
-
(2015)
Angew. Chem. Int. Ed.
, vol.54
, pp. 15794
-
-
Kitsiou, C.1
Hindes, J.J.2
I'Anson, P.3
Jackson, P.4
Wilson, T.C.5
Daly, E.K.6
Felstead, H.R.7
Hearnshaw, P.8
Unsworth, W.P.9
-
27
-
-
84990236082
-
-
Angew. Chem. 2015, 127, 16020.
-
(2015)
Angew. Chem.
, vol.127
, pp. 16020
-
-
-
28
-
-
79955552261
-
-
E. Comer, H. Liu, A. Joliton, A. Clabaut, C. Johnson, L. B. Akella, L. A. Marcaurelle, Proc. Natl. Acad. Sci. USA 2011, 108, 6751.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 6751
-
-
Comer, E.1
Liu, H.2
Joliton, A.3
Clabaut, A.4
Johnson, C.5
Akella, L.B.6
Marcaurelle, L.A.7
-
29
-
-
85043106911
-
-
For the build-couple-pair strategy see
-
For the build-couple-pair strategy see:
-
-
-
-
31
-
-
84990192870
-
-
For the synthesis of macrocycles using the B/C/P strategy see
-
Angew. Chem. 2008, 120, 52. For the synthesis of macrocycles using the B/C/P strategy see:
-
(2008)
Angew. Chem.
, vol.120
, pp. 52
-
-
-
32
-
-
79955562617
-
-
A. Isidro-Llobet, T. Murillo, P. Bello, A. Cilibrizzi, J. T. Hodgkinson, W. R. J. D. Galloway, A. Bender, M. Welch, D. R. Spring, Proc. Natl. Acad. Sci. USA 2011, 108, 6793;
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 6793
-
-
Isidro-Llobet, A.1
Murillo, T.2
Bello, P.3
Cilibrizzi, A.4
Hodgkinson, J.T.5
Galloway, W.R.J.D.6
Bender, A.7
Welch, M.8
Spring, D.R.9
-
33
-
-
84915758781
-
-
A. Grossmann, S. Bartlett, M. Janecek, J. T. Hodgkinson, D. R. Spring, Angew. Chem. Int. Ed. 2014, 53, 13093;
-
(2014)
Angew. Chem. Int. Ed.
, vol.53
, pp. 13093
-
-
Grossmann, A.1
Bartlett, S.2
Janecek, M.3
Hodgkinson, J.T.4
Spring, D.R.5
-
34
-
-
84955261135
-
-
Angew. Chem. 2014, 126, 13309;
-
(2014)
Angew. Chem.
, vol.126
, pp. 13309
-
-
-
36
-
-
80054099902
-
-
S. Dandapani, J. T. Lowe, E. Comer, L. A. Marcaurelle, J. Org. Chem. 2011, 76, 8042;
-
(2011)
J. Org. Chem.
, vol.76
, pp. 8042
-
-
Dandapani, S.1
Lowe, J.T.2
Comer, E.3
Marcaurelle, L.A.4
-
37
-
-
84856936324
-
-
M. E. Fitzgerald, C. A. Mulrooney, J. R. Duvall, J. Wei, B. Suh, L. B. Akella, A. Vrcic, L. A. Marcaurelle, ACS Comb. Sci. 2012, 14, 89;
-
(2012)
ACS Comb. Sci.
, vol.14
, pp. 89
-
-
Fitzgerald, M.E.1
Mulrooney, C.A.2
Duvall, J.R.3
Wei, J.4
Suh, B.5
Akella, L.B.6
Vrcic, A.7
Marcaurelle, L.A.8
-
39
-
-
85043122377
-
-
CCDC 1458977 contains the supplementary crystallographic data for this paper. These data can be obtained free of charge from The, Crystallographic Data Centre.
-
CCDC 1458977 contains the supplementary crystallographic data for this paper. These data can be obtained free of charge from The Cambridge Crystallographic Data Centre.
-
-
-
-
40
-
-
65949123562
-
-
K. D. Closser, M. M. Quintal, K. M. Shea, J. Org. Chem. 2009, 74, 3680;
-
(2009)
J. Org. Chem.
, vol.74
, pp. 3680
-
-
Closser, K.D.1
Quintal, M.M.2
Shea, K.M.3
-
41
-
-
34250673184
-
-
E. Comer, E. Rohan, L. Deng, J. A. Porco, Jr., Org. Lett. 2007, 9, 2123.
-
(2007)
Org. Lett.
, vol.9
, pp. 2123
-
-
Comer, E.1
Rohan, E.2
Deng, L.3
Porco, J.A.4
-
44
-
-
84864588389
-
-
W. S. Brotherton, R. J. Clark, L. Zhu, J. Org. Chem. 2012, 77, 6443.
-
(2012)
J. Org. Chem.
, vol.77
, pp. 6443
-
-
Brotherton, W.S.1
Clark, R.J.2
Zhu, L.3
|