Replication of Plasmodium in reticulocytes can occur without hemozoin formation, resulting in chloroquine resistance

Journal of Experimental Medicine

Volumn 212, Issue 6, 2015, Pages 893-903

  Lin, Jing wen ^a,g,j   Spaccapelo, Roberta ^b   Schwarzer, Evelin ^c   Sajid, Mohammed ^a   Annoura, Takeshi ^h   Deroost, Katrien ^d   Ravelli, Raimond B G ^a,i   Aime, Elena ^b   Capuccini, Barbara ^b,g   Mommaas Kienhuis, Anna M ^a   O'Toole, Tom ^e   Prins, Frans ^a   Franke Fayard, Blandine M D ^a   Ramesar, Jai ^a   Chevalley Maurel, Séverine ^a   Kroeze, Hans ^a   Koster, Abraham J ^a   Tanke, Hans J ^a   Crisanti, Andrea ^b,f   Langhorne, Jean ^g,j   Arese, Paolo ^c   Van den Steen, Philippe E ^d   Janse, Chris J ^a   Khan, Shahid M ^a   more..

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF PERUGIA   (Italy)

^c UNIVERSITY OF TURIN   (Italy)

^d REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^e VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^f IMPERIAL COLLEGE LONDON   (United Kingdom)

^g NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^h JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

ⁱ MAASTRICHT UNIVERSITY   (Netherlands)

^j THE FRANCIS CRICK INSTITUTE   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ARTESUNATE; CHLOROQUINE; HEMOGLOBIN; HEMOZOIN; ANTIMALARIAL AGENT; ARTEMISININ DERIVATIVE; HEMOPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DEGRADATION; DRUG RESISTANCE; FEMALE; GAMETOCYTE; GENE DELETION; MOUSE; NONHUMAN; PARASITE VIRULENCE; PLASMODIUM; PRIORITY JOURNAL; RETICULOCYTE; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; CYTOLOGY; CYTOPLASM; ERYTHROCYTE; MALARIA; MALE; METABOLISM; MUTATION; PARASITOLOGY; PLASMODIUM BERGHEI; REPORTER GENE;

ANIMALS; ANTIMALARIALS; ARTEMISININS; CHLOROQUINE; CYTOPLASM; DRUG RESISTANCE; ERYTHROCYTES; FEMALE; GENE DELETION; GENES, REPORTER; HEMEPROTEINS; HEMOGLOBINS; MALARIA; MALE; MICE; MICE, INBRED BALB C; MUTATION; PLASMODIUM BERGHEI; RETICULOCYTES;

EID: 84980022414     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20141731     Document Type: Article

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