Plasmepsin 4-deficient Plasmodium berghei are virulence attenuated and induce protective immunity against experimental malaria

American Journal of Pathology

Volumn 176, Issue 1, 2010, Pages 205-217

  Spaccapelo, Roberta ^a   Janse, Chris J ^b   Caterbi, Sara ^a   Franke Fayard, Blandine ^b   Bonilla, J Alfredo ^c   Syphard, Luke M ^c   Di Cristina, Manlio ^a   Dottorini, Tania ^a   Savarino, Andrea ^d   Cassone, Antonio ^d   Bistoni, Francesco ^a   Waters, Andrew P ^b,f   Dame, John B ^c   Crisanti, Andrea ^a,e  

^a UNIVERSITY OF PERUGIA   (Italy)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF FLORIDA   (United States)

^d ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^e IMPERIAL COLLEGE LONDON   (United Kingdom)

^f UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC PROTEINASE; PLASMEPSIN 4; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; BRAIN DISEASE; BRAIN MALARIA; CONTROLLED STUDY; GENE DISRUPTION; GENE MUTATION; IMMUNE RESPONSE; IMMUNITY; MALARIA; MOUSE; NONHUMAN; PARASITE VIRULENCE; PLASMODIUM BERGHEI; PRIORITY JOURNAL; WILD TYPE;

EID: 73949084280     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2010.090504     Document Type: Article

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