Post-mortem magnetic resonance foetal imaging: a study of morphological correlation with conventional autopsy and histopathological findings

Radiologia Medica

Volumn 121, Issue 11, 2016, Pages 847-856

  Vullo, Annamaria ^a   Panebianco, Valeria ^a   Cannavale, Giuseppe ^a   Aromatario, Mariarosaria ^a   Cipolloni, Luigi ^a   Frati, Paola ^a   Santurro, Alessandro ^a   Vullo, Francesco ^a   Catalano, Carlo ^a   Fineschi, Vittorio ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Foetal and perinatal autopsy; Histological examination; Post mortem magnetic resonance

Indexed keywords

ADULT; AUTOPSY; FEMALE; FETUS DEATH; HUMAN; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; POSTMORTEM CHANGE; PREGNANCY; PROCEDURES;

ADULT; AUTOPSY; FEMALE; FETAL DEATH; HUMANS; MAGNETIC RESONANCE IMAGING; MIDDLE AGED; POSTMORTEM CHANGES; PREGNANCY;

EID: 84979971349     PISSN: 00338362     EISSN: 18266983     Source Type: Journal    
DOI: 10.1007/s11547-016-0672-z     Document Type: Article

References (57)

1. Thali MJ, Dirnhofer R, Beckerc R, Oliverc W, Potter K (2004) Is ‘virtual histology’ the next step after the ‘virtual autopsy’? Magnetic resonance microscopy in forensic medicine. Magn Reson Imaging 22:1131–1138
2. Yen K, Lövblad KO, Scheurer E, Ozdoba C, Thali MJ, Aghayev E, Jackowski C, Anon J, Frickey N, Zwygart K, Weis J, Dirnhofer R (2007) Post-mortem forensic neuroimaging: correlation of MSCT and MRI findings with autopsy results. Forensic Sci Int 173:21–35
3. Guddat SS, Gapert R, Tsokos M, Oesterhelweg L (2013) Proof of live birth using postmortem multislice computed tomography (pmMSCT) in cases of suspected neonaticide: advantages of diagnostic imaging compared to conventional autopsy. Forensic Sci Med Pathol 9:3–12
4. Pomara C, Fineschi V, Scalzo G, Guglielmi G (2009) Virtopsy versus digital autopsy: virtuous autopsy. Radiol Med 114:1367–1382
5. Frøen JF, Cacciatore J, McClure EM, Kuti O, Jokhio AH, Islam M, Shiffman J, Lancet’s Stillbirths Series steering committee (2011) Stillbirths: why they matter. Lancet 377:1353–1366
6. Flenady V, Koopmans L, Middleton P, Frøen JF, Smith GC, Gibbons K, Coory M, Gordon A, Ellwood D, McIntyre HD, Fretts R, Ezzati M (2011) Major risk factors for stillbirth in high-income countries: a systematic review and meta-analysis. Lancet 377:1331–1340
7. Goldenberg RL, McClure EM, Bhutta ZA, Belizan JM, Reddy UM, Rubens CE, Mabeya H, Flenady V, Darmstadt GL, Lancet’s Stillbirths Series steering committee (2011) Stillbirths: the vision for 2020. Lancet 377:1798–1805
8. Pattinson R, Kerber K, Buchmann E, Friberg IK, Belizan M, Lansky S, Weissman E, Mathai M, Rudan I, Walker N, Lawn JE, Lancet’s Stillbirths Series steering committee (2011) Stillbirths: how can health systems deliver for mothers and babies? Lancet 377:1523–1538
9. Thayyil S, Sebire NJ, Chitty LS, Wade A, Olsen O, Gunny RS, Offiah A, Saunders DE, Owens CM, Chong WK, Robertson NJ, Taylor AM (2011) Post mortem magnetic resonance imaging in the fetus, infant and child: a comparative study with conventional autopsy (MaRIAS Protocol). BMC Pediatr 11:120
10. Helgadõttir LB, Turowski G, Skjeldestad FE, Jacobsen AF, Sandset PM, Roald B, Jacobsen EM (2013) Classification of stillbirths and risk factors by cause of death. A case-control study. Acta Obstet Gynecol Scand 92:325–333
11. King JF, Warren RA (2006) The role of reviews of perinatal deaths. Semin Fetal Neonatal Med 11:79–87
12. Nappi L, Trezza F, Bufo P, Riezzo I, Turillazzi E, Borghi C, Bonaccorsi G, Scutiero G, Fineschi V, Greco P (2016) Classification of stillbirths is an ongoing dilemma. J Perinat Med. doi:10.1515/jpm-2015-0318
13. Ofir K, Kalter A, Moran O, Sivan E, Schiff E, Simchen MJ (2013) Subsequent pregnancy after stillbirth: obstetrical and medical risks. J Perinat Med 41:543–548
14. Woodward PJ, Sohaey R, Harris DP, Jackson GM, Klatt EC, Alexander AL, Kennedy A (1997) Postmortem fetal MR imaging: comparison with findings at autopsy. AJR Am J Roentgenol 168:41–46
15. Huisman TA (2004) Magnetic resonance imaging: an alternative to autopsy in neonatal death? Semin Neonatol 9:347–353
16. Whitby EH, Paley MN, Cohen M, Griffiths PD (2005) Postmortem MR imaging of the fetus: an adjunct or a replacement for conventional autopsy? Semin Fetal Neonatal Med 10:475–483
17. Griffiths PD, Paley MN, Whitby EH (2005) Post-mortem MRI as an adjunct to fetal or neonatal autopsy. Lancet 365:1271–1273
18. Becker GJ (2005) Virtues of virtual autopsy. J Am Coll Radiol 2:376–378
19. Dirnhofer R, Jackowski C, Vock P, Potter K, Thali MJ (2006) Virtopsy: minimally invasive, imaging-guided virtual autopsy. Radiographics 26:1305–1333
20. Brookes JS, Hagmann C (2006) MRI in fetal necropsy. J Magn Reson Imaging 24:1221–1228
21. Whitby EH, Paley MN, Cohenb M, Griffiths PD (2006) Post-mortem fetal MRI: what do we learn from it? Eur J Radiol 57:250–255
22. Clarot F, Proust B, Eurin D, Vaz E, Le Dosseur P (2007) Sudden infant death syndrome and virtual autopsy: scalpel or mouse? Arch Pediatr 14:623–629
23. Rutty GN, Rutty JE (2001) Perceptions of near virtual autopsies. J Forensic Leg Med 18:306–309
24. Valdés Dapena M, Huff DS (1983) Perinatal autopsy manual. Armed Forces Institute of Pathology, Washington, DC
25. Pomara C, Karch SB, Fineschi V (2010) Forensic autopsy. A handbook and atlas. CRC Press, Boca Raton
26. Arthurs OJ, Barber JL, Taylor AM, Sebire NJ (2015) Normal perinatal and paediatric post-mortem magnetic resonance imaging appearances. Pediatr Radiol 45:527–535
27. Bonetti LR, Ferrari P, Trani N, Maccio L, Laura S, Giuliana S, Facchinetti F, Rivasi F (2011) The role of fetal autopsy and placental examination in the causes of fetal death: a retrospective study of 132 cases of stillbirths. Arch Gynecol Obstet 283:231–241
28. Miller ES, Minturn L, Linn R, Weese-Mayer DE, Ernst LM (2016) Stillbirth evaluation: a stepwise assessment of placental pathology and autopsy. Am J Obstet Gynecol 214:115e1–115e6
29. Heller DS, Faye-Petersen OM (2015) Pathology of the stillborn infant for the general pathologist: part 1. Adv Anat Pathol 22:1–28
30. Fretts RC, Boyd ME, Usher RH, Usher HA (1992) The changing pattern of fetal death, 1961–1988. Obstet Gynecol 79:35–39
31. Fretts RC (2005) Etiology and prevention of stillbirth. Am J Obst Gynecol 193:1923–1935
32. Vergani P, Cozzolino S, Pozzi E, Cuttin MS, Greco M, Ornaghi S, Lucchini V (2008) Identifyng the causes of stillbirth: a comparison of four classification systems. Am J Obstet Gynecol 199:319e1–319e4
33. Lamont K, Scott NW, Jones GT, Bhattacharya S (2015) Risk of recurrent stillbirth: systematic review and meta-analysis. BMJ 350:h3080
34. Simpson LL (2002) Maternal medical disease: risk of antepartum fetal death. Semin Perinatol 26:42–50
35. Korteweg FJ, Erwich JJ, Holm JP, Ravisé JM, van der Meer J, Veeger NJ, Timmer A (2009) Diverse placental pathologies as the main causes of fetal death. Obstet Gynecol 114:809–817
36. McClure EM, Dudley DJ, Reddy UM, Goldenberg RL (2010) Infectious causes of stillbirth: a clinical perspective. Clin Obstet Gynecol 53:635–645
37. Frøen JF, Gardosi JO, Thurmann A, Francis A, Stray-Pedersen B (2004) Restricted fetal growth in sudden intrauterine unexplained death. Acta Obstet Gynecol Scand 83:801–807
38. Italian Ministry of Health. Decree October 7, 2014. www.gazzettaufficiale.it/eli/id/2014/11/22/14A08847/sg
39. Gorincour G, Chaumoitre K, Bourliere-Najean B, Bretelle F, Sigaudy S, D’Ercole C, Philip N, Potier A, Petit P, Panuel M (2014) Fetal skeletal computed tomography: when? How? Why? Diagn Interv Imaging 95:1045–1053
40. Votino C, Cannie M, Segers V, Dobrescu O, Dessy H, Gallo V, Cos T, Damry N, Jani J (2012) Virtual autopsy by computed tomographic angiography of the fetal heart: a feasibility study. Ultrasound Obstet Gynecol 39:679–684
41. Sarda-Quarello L, Bartoli C, Laurent PE, Torrents J, Piercecchi-Marti MD, Sigaudy S, Ariey-Bonnet D, Gorincour G (2016) Whole body perinatal postmortem CT angiography. Diagn Interv Imaging 97:121–124
42. Sarda-Quarello L, Tuchtan L, Torrents J, Piercecchi-Marti MD, Bartoli C, Laurent PE, Bourlière-Najean B, Petit P, Quarello E, Gorincour G (2015) Perinatal death: is there a place for post-mortem angio-CT? J Forensic Radiol Imaging 3:1–4
43. Arthurs OJ, Thayyil S, Pauliah SS, Jacques TS, Chong WK, Gunny R, Saunders D, Addison S, Lally P, Cady E, Jones R, Norman W, Scott R, Robertson NJ, Wade A, Chitty L, Taylor AM, Sebire NJ, Magnetic Resonance Imaging Autopsy Study (MARIAS) Collaborative Group (2015) Diagnostic accuracy and limitations of post-mortem MRI for neurological abnormalities in fetuses and children. Clin Radiol 70:872–880
44. Orasanu E, Melbourne A, Cardoso MJ, Modat M, Taylor AM, Thayyil S, Ourselin S (2014) Brain volume estimation from post-mortem newborn and fetal MRI. Neuroimage Clin 6:438–444
45. Arthurs OJ, Thayyil S, Olsen OE, Addison S, Wade A, Jones R, Norman W, Scott RJ, Robertson NJ, Taylor AM, Chitty LS, Sebire NJ, Owens CM, Magnetic Resonance Imaging Autopsy Study (MARIAS) Collaborative Group (2014) Diagnostic accuracy of post-mortem MRI for thoracic abnormalities in fetuses and children. Eur Radiol 24:2876–2884
46. Thayyil S, Cleary JO, Sebire NJ, Scott RJ, Chong K, Gunny R, Owens CM, Olsen OE, Offiah AC, Parks HG, Chitty LS, Price AN, Yousry TA, Robertson NJ, Lythgoe MF, Taylor AM (2009) Post-mortem examination of human fetuses: a comparison of whole-body high-field MRI at 9.4 T with conventional MRI and invasive autopsy. Lancet 374:467–475
47. Sarikouch S, Haas NA, Schaeffler R, Beerbaum P (2008) Value of postmortem magnetic resonance imaging for fatal neonatal congenital heart disease: a case report. Pediatr Cardiol 29:667–669
48. Taylor AM, Sebire NJ, Ashworth MT, Schievano S, Scott RJ, Wade A, Chitty LS, Robertson N, Thayyil S, Magnetic Resonance Imaging Autopsy Study Collaborative Group (2014) Postmortem cardiovascular magnetic resonance imaging in fetuses and children. A masked comparison study with conventional autopsy. Circulation 129:1937–1944
49. Arthurs OJ, Owens CM, Olsen OE, Wade A, Addison S, Jones R, Norman W, Scott RJ, Robertson NJ, Taylor AM, Chitty LS, Sebire NJ, Magnetic Resonance Imaging Autopsy Study (MaRIAS) Collaborative Group (2015) Diagnostic accuracy of post mortem MRI for abdominal abnormalities in foetuses and children. Eur J Radiol 84:474–481
50. Addison S, Arthurs OJ, Thayyil S (2014) Post-mortem MRI as an alternative to non-forensic autopsy in foetuses and children: from research into clinical practice. Br J Radiol 87:20130621
51. Arthurs OJ, Calder AD, Klein WM (2015) Is there still a role for foetal and perinatal post-mortem radiography? J Forensic Radiol Imaging 3:5–11
52. Arthurs OJ, Thayyil S, Addison S, Wade A, Jones R, Norman W, Scott R, Robertson NJ, Chitty LS, Taylor AM, Sebire NJ, Offiah AC, and for the Magnetic Resonance Imaging Autopsy Study (MARIAS) Collaborative Group (2014) Diagnostic accuracy of postmortem MRI for musculoskeletal abnormalities in fetuses and children. Prenat Diagn 34:1254–1261
53. Ofir K, Kalter A, Moran O, Sivan E, Schiff E, Simchen MJ (2013) Subsequent pregnancy after stillbirth: obstetrical and medical risks. J Perinat Med 41:543–548
54. Thayyl S, Sebire NJ, Chitty LS, Wade A, Chong WK, Isen O, Gunny RS, Offiah AC, Owens CM, Saunders DE, Scott RJ, Jones R, Norman W, Addison S, Bainbridge A, Cady EB, De Vita E, Robertson NJ, Taylor AM, MARIAS collaborative group (2013) Post-mortem MRI versus conventional autopsy in fetuses and children: a prospective validation study. Lancet 382:223–233
55. Gorincour G, Sarda-Quarello L, Laurent PE, Brough A, Rutty GN (2015) The future of pediatric and perinatal postmortem imaging. Pediatr Radiol 45:509–516
56. Cohen MC, Whitby E (2007) The use of magnetic resonance in the hospital and coronial pediatric postmortem examination. Forensic Sci Med Pathol 3:289–296
57. Guglielmi G, Nasuto M, Pinto A (2015) Forensic and medico-legal radiology: challenges, issues and new perspectives. Radiol Med 120:777–778