Impact of familial hypertrophic cardiomyopathy-linked mutations in the NH2 terminus of the RLC on β-myosin cross-bridge mechanics

Journal of Applied Physiology

Volumn 117, Issue 12, 2014, Pages 1471-1477

  Farman, Gerrie P ^a   Muthu, Priya ^b   Kazmierczak, Katarzyna ^b   Szczesna Cordary, Danuta ^b   Moore, Jeffrey R ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Cardiac ventricular myosin; Hypertrophic cardiomyopathy; In vitro motility; Myosin regulatory light chain

Indexed keywords

CARDIAC MYOSIN; MYOSIN HEAVY CHAIN; MYOSIN LIGHT CHAIN; PROTEIN BINDING; RECOMBINANT PROTEIN;

ANIMAL; CARDIAC MUSCLE CELL; FAMILIAL HYPERTROPHIC CARDIOMYOPATHY; GENETIC PREDISPOSITION; GENETICS; HEART CONTRACTION; HUMAN; KINETICS; METABOLISM; MUTATION; PATHOPHYSIOLOGY; PHENOTYPE; PIG; PROTEIN DOMAIN;

ANIMALS; CARDIAC MYOSINS; CARDIOMYOPATHY, HYPERTROPHIC, FAMILIAL; GENETIC PREDISPOSITION TO DISEASE; HUMANS; KINETICS; MUTATION; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; MYOSIN HEAVY CHAINS; MYOSIN LIGHT CHAINS; PHENOTYPE; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; RECOMBINANT PROTEINS; SWINE;

EID: 84979862406     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00798.2014     Document Type: Article

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