Myosin regulatory light chain E22K mutation results in decreased cardiac intracellular calcium and force transients

FASEB Journal

Volumn 21, Issue 14, 2007, Pages 3974-3985

  Szczesna Cordary, Danuta ^a   Jones, Michelle ^a   Moore, Jeffrey R ^b   Watt, James ^b   Kerrick, W Glenn L ^a   Xu, Yuanyuan ^a   Wang, Ying ^a   Wagg, Cory ^c   Lopaschuk, Gary D ^c  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Ca2+ Mg2+ binding to RLC; Cardiac hypertrophy; Energy metabolism; In vitro motility assays; Intact and skinned muscle fibers; Transgenic mice

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; MYOSIN;

ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; ENERGY METABOLISM; GENE MUTATION; IN VITRO STUDY; MOUSE; MUSCLE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AMINO ACID SUBSTITUTION; ANIMALS; CALCIUM; DOWN-REGULATION; FEMALE; GLUTAMIC ACID; HUMANS; INTRACELLULAR FLUID; LYSINE; MALE; MICE; MICE, TRANSGENIC; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOSIN LIGHT CHAINS;

MUS; MUS MUSCULUS;

EID: 36849094890     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.07-8630com     Document Type: Article

References (44)

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