The effect of removing the N-terminal extension of the Drosophila myosin regulatory light chain upon flight ability and the contractile dynamics of indirect flight muscle

Biophysical Journal

Volumn 78, Issue 3, 2000, Pages 1431-1440

  Moore, Jeffrey R ^a   Dickinson, Michael H ^a   Vigoreaux, Jim O ^b   Maughan, David W ^a  

^a UNIVERSITY OF VERMONT   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MYOSIN LIGHT CHAIN;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DROSOPHILA; FLIGHT MUSCLE; GENE CONSTRUCT; GENE EXPRESSION; GENE MUTATION; GERM LINE; LETHALITY; MUSCLE CONTRACTILITY; MUSCLE FORCE; MUSCLE STRENGTH; MYOFILAMENT; NONHUMAN; PHENOTYPE; SARCOMERE; SKINNED MUSCLE FIBER; THIN FILAMENT; YOUNG MODULUS;

ANIMALIA; ARENA; VERTEBRATA;

EID: 0034008021     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(00)76696-3     Document Type: Article

References (43)

1. Anson, M., D. R. Drummond, M. A. Geeves, E. S. Hennessey, M. D. Ritchie, and J. C. Sparrow. 1995. Actomyosin kinetics and in vitro motility of wild-type Drosophila actin and the effects of two mutations in the Act88F gene. Biophys. J. 68:1991-2003.
2. Bernstein, S. I., P. T. O'Donnell, and R. M. Cripps. 1993. Molecular genetic analysis of muscle development, structure, and function in Drosophila. Int. Rev. Cytol. 143:63-152.
3. Checci, G., and M. Bagni. 1994. Myofilament lattice spacing affects tension in striated muscle. News Physiol. Sci. 9:3-7.
4. Collins, J. H. 1991. Myosin light chains and troponin C: structural and evolutionary relationships revealed by amino acid sequence comparisons. J. Muscle Res. Cell Motil. 12:3-25.
5. Dickinson, M. H., C. J. Hyatt, F. Lehmann, J. R. Moore, M. C. Reedy, A. Simcox, R. Tohtong, J. O. Vigoreaux, H. Yamashita, and D. W. Maughan. 1997. Phosphorylation-dependent power output of transgenic flies: an integrated study. Biophys. J. 73:3122-3134.
6. Dickinson, M. H., and J. R. B. Lighton. 1995. Muscle efficiency and elastic storage in the flight motor of Drosophila melanogaster. Science. 128: 87-89.
7. Dickinson, M. H., and Tu. 1998. The function of Dipteran flight muscle. Comp. Biochem. Physiol. 116A:223-238.
8. Drummond, D. R., M. Peckham, J. C. Sparrow, and D. C. S. White. 1990. Alteration in cross-bridge kinetics caused by mutations in actin. Nature. 348:440-442.
9. Granzier, H. L. M., and K. Wang. 1993. Interplay between passive tension and strong and weak binding cross-bridges in insect indirect flight muscle: a functional dissection by gelsolin-mediated thin filament removal. J. Gen. Physiol. 101:235-270.
10. Hill, T. L., E. Eisenberg, and L. Greene. 1980. Theoretical model for the cooperative equilibrium binding of myosin subfragment 1 to the actintroponin-tropomyosin complex. Proc. Natl. Acad. Sci. USA. 77: 3186-3190.
11. Hyatt, C. J., and D. W. Maughan. 1994. Fourier analysis of wing beat signals: assessing the effects of genetic alterations of flight muscle structure in Diptera. Biophys. J. 67:1149-1154.
12. Josephson, R. K. 1993. Contraction dynamics and power output of skeletal muscle. Annu. Rev. Physiol. 55:527-546
13. Lehmann, F.-O., and M. H. Dickinson. 1997. The changes in power requirements and muscle efficiency during elevated force production in the fruit fly, Drosophila melanogaster. J. Exp. Biol. 200:1133-1143.
14. Metzger, J. M., M. L. Greaser, and R. L. Moss. 1989. Variations in cross-bridge attachment rate and tension with phosphorylation of myosin in mammalian skinned skeletal muscle fibers: implications for twitch potentiation in intact muscle. J. Gen. Physiol. 93:855-883.
15. Milligan, R. A., M. Whittaker, and D. Safer. 1990. Molecular structure of F-actin and location of surface binding sites. Nature. 348:217-221.
16. Millman, B. M. 1998. The filament lattice of striated muscle. Physiol. Rev. 78:359-391.
17. Maughan, D. W., and J. O. Vigoreaux. 1999. An integrated view of insect flight muscle: genes, motor molecules and motion. News Physiol. Sci. 14:87-92.
18. Mogami, K., S. C. Fugita, and Y. Hotta. 1982. Identification of Drosophila indirect flight muscle myofibrillar proteins by means of two-dimensional electrophoresis. J. Biochem. 91:643-650.
19. Morano, I., O. Ritter, A. Bonz, T. Timek, C. F. Vahl, and G. Michel. 1995. Myosin light chain-actin interaction regulates cardiac contractility. Circ. Res. 76:720-725.
20. Morano, M., U. Zacharzowski, M. Maier, P. E. Lange, V. Alexi-Meskishvili, and H. Haase. 1996. Regulation of human heart contractility by essential myosin light chain isoforms. J. Clin. Invest. 98:467-473.
21. Parker, V. P., S. Falkenthal, and N. Davidson. 1985. Characterization of the myosin light-chain-2 gene of Drosophila melanogaster. Mol. Cell. Biol. 5:3058-3068.
22. Persechini, A., J. T. Stull, and R. Cooke. 1985. The effect of myosin phosphorylation on the contractile properties of skinned rabbit skeletal muscle fibers. J. Biol. Chem. 260:7951-7954.
23. Pirrotta, V. 1988. Vectors for P-mediated transformation in Drosophila. Biotechnology. 10:437-456.
24. Poetter, K., H. Jiang, S. Hassanzadeh, S. R. Master, A. Chang, M. C. Dalakas, I. Rayment, J. R. Sellers, L. Fananapazir, and N. D. Epstein. 1996. Mutations in either the essential or regulatory light chains of myosin are associated with a rare myopathy in human heart and skeletal muscle. Nature Genet. 13:63-69.
25. Pringle, J. W. S. 1978. The Croonian Lecture, 1977. Stretch activation of muscle; function and mechanism. Proc. R. Soc. Lond. B. 201:107-130.
26. Rarick, H. M., T. J. Opgenorth, T. W. von Geldern, J. R. Wu-Wong, and R. J. Solaro. 1996. An essential myosin light chain peptide induces supramaximal stimulation of cardiac myofibrillar ATPase activity. J. Biol. Chem. 271:27039-27043.
27. Reedy, M. C., M. K. Reedy, K. R. Leonard, and B. Bullard. 1994. Gold/Fab immuno electron microscopy localization of troponin H and troponin T in Lethocerus flight muscle. J. Mol. Biol. 239:52-67.
28. Rubin, G. M., and A. C. Spradling. 1982. Genetic transformation of Drosophila with transposable element vectors. Science. 218:348-353.
29. Schaub, M. C., M. A. Hefti, R. A. Zuellig, and I. Morano. 1998. Modulation of contractility in human cardiac hypertrophy by myosin essential light chain isoforms. Cardiovasc. Res. 37:381-404.
30. Steiger, G. J. 1977. Stretch activation and tension transients in cardiac, skeletal and insect flight muscle. In Insect Flight Muscle. R. T. Tregear, editor. Elsevier North Holland Biomedical Press, Amsterdam. 221-268.
31. Sutoh, K. 1982. Identification of myosin binding sites on the actin sequence. Am. Chem. Soc. 21:3654-3661.
32. Sweeney, H. L. 1995. Function of the N terminus of the myosin essential light chain of vertebrate striated muscle. Biophys. J. 68:112s-119s.
33. Sweeney, H. L., B. F. Bowman, and J. T. Stull. 1993. Myosin light chain phosphorylation in vertebrate striated muscle: regulation and function. Am. J. Physiol. 264:C1085-C1095.
34. Takano-Ohmuro, H., S. Takahashi, G. Hirose, and K. Maruyama. 1990. Phosphorylated and dephosphorylated myosin light chains of Drosophila fly and larva. Comp. Biochem. Physiol. 95B:171-177.
35. Thorson, J., and D. C. S. White. 1983. Role of cross-bridge distortion in the small-signal mechanical dynamics of insect and rabbit striated muscle. J. Physiol. (Lond.). 343:59-84.
36. Timson, D. J., and I. P. Trayer. 1997. The role of the proline-rich region in A1-type myosin essential light chains: implications for information transmission in the actomyosin complex. FEBS Lett. 400:31-36.
37. Toffenetti, J., D. Mischke, and M. L. Pardue. 1987. Isolation and characterization of the gene for myosin light chain two of Drosophila melanogaster. J. Cell Biol. 104:19-28.
38. Tohtong, R., H. Yamashita, M. Graham, J. Haeberle, A. Simcox, and D. Maughan. 1995. Impairment of muscle function caused by mutations of phosphorylation sites in myosin regulatory light chain. Nature. 374: 650-653.
39. Trayer, I. P., H. R. Trayer, and B. A. Levine. 1987. Evidence that the N-terminal region of A1-light chain of myosin interacts directly with the C-terminal region of actin: a proton magnetic resonance study. Eur. J. Biochem. 164:259-266.
40. Trybus, K. M. 1994. Role of myosin light chains. J. Muscle Res. Cell Motil. 15:587-594.
41. Vemuri, R., E. B. Lankford, K. Poetter, S. Hassanzadeh, K. Takeda, Z. X. Yu, V. J. Ferrans, and N. D. Epstein. 1999. The stretch-activation response may be critical to the proper functioning of the mammalian heart. Proc. Natl. Acad Sci. USA. 96:1048-1053.
42. Warmke, J., M. Yamakawa, J. E. Molloy, S. Falkenthal, and D. W. Maughan. 1992. A myosin light chain-2 mutation affects flight, wing beat frequency and indirect flight muscle contraction kinetics in Drosophila. J. Cell Biol. 119:1523-1536.
43. Williamson, M. P. 1994. The structure and function of proline-rich regions in proteins. Biochem. J. 297:249-260.