메뉴 건너뛰기




Volumn 32, Issue 9, 2016, Pages

Secretome, surfome and immunome: emerging approaches for the discovery of new vaccine candidates against bacterial infections

Author keywords

Exoproteome; Immunoproteomics; Surface proteome; Vaccine

Indexed keywords

ANTIBODIES; ANTIGENS; BACTERIA; MOLECULAR BIOLOGY; PATHOGENS; PROTEINS;

EID: 84979692019     PISSN: 09593993     EISSN: 15730972     Source Type: Journal    
DOI: 10.1007/s11274-016-2107-3     Document Type: Review
Times cited : (16)

References (60)
  • 2
    • 58249109483 scopus 로고    scopus 로고
    • Immunization against Clostridium perfringens cells elicits protection against Clostridium tetani in mouse model: identification of cross-reactive proteins using proteomic methodologies
    • Alam SI, Bansod S, Singh L (2008) Immunization against Clostridium perfringens cells elicits protection against Clostridium tetani in mouse model: identification of cross-reactive proteins using proteomic methodologies. BMC Microbiol 8:194
    • (2008) BMC Microbiol , vol.8 , pp. 194
    • Alam, S.I.1    Bansod, S.2    Singh, L.3
  • 3
    • 69449098311 scopus 로고    scopus 로고
    • Differential proteomic analysis of Clostridium perfringens ATCC13124; identification of dominant, surface and structure associated proteins
    • Alam SI, Bansod S, Kumar RB, Sengupta N, Singh L (2009) Differential proteomic analysis of Clostridium perfringens ATCC13124; identification of dominant, surface and structure associated proteins. BMC Microbiol 9:162
    • (2009) BMC Microbiol , vol.9 , pp. 162
    • Alam, S.I.1    Bansod, S.2    Kumar, R.B.3    Sengupta, N.4    Singh, L.5
  • 4
    • 0042265058 scopus 로고    scopus 로고
    • Genome-based bioinformatic selection of chromosomal Bacillus anthracis putative vaccine candidates coupled with proteomic identification of surface-associated antigens
    • COI: 1:CAS:528:DC%2BD3sXlvFyktbc%3D
    • Ariel N, Zvi A, Makarova KS, Chitlaru T, Elhanany E, Velan B, Cohen S, Friedlander AM, Shafferman A (2003) Genome-based bioinformatic selection of chromosomal Bacillus anthracis putative vaccine candidates coupled with proteomic identification of surface-associated antigens. Infect Immun 71(8):4563–4579
    • (2003) Infect Immun , vol.71 , Issue.8 , pp. 4563-4579
    • Ariel, N.1    Zvi, A.2    Makarova, K.S.3    Chitlaru, T.4    Elhanany, E.5    Velan, B.6    Cohen, S.7    Friedlander, A.M.8    Shafferman, A.9
  • 5
    • 17044389822 scopus 로고    scopus 로고
    • Subproteomes of soluble and structure-bound Helicobacter pylori proteins analyzed by two-dimensional gel electrophoresis and mass spectrometry
    • COI: 1:CAS:528:DC%2BD2MXjtlSjtbc%3D
    • Backert S, Kwok T, Schmid M, Selbach M, Moese S, Peek RM Jr, König W, Meyer TF, Jungblut PR (2005) Subproteomes of soluble and structure-bound Helicobacter pylori proteins analyzed by two-dimensional gel electrophoresis and mass spectrometry. Proteomics 5:1331–1345
    • (2005) Proteomics , vol.5 , pp. 1331-1345
    • Backert, S.1    Kwok, T.2    Schmid, M.3    Selbach, M.4    Moese, S.5    Peek, R.M.6    König, W.7    Meyer, T.F.8    Jungblut, P.R.9
  • 9
    • 33745973006 scopus 로고    scopus 로고
    • Proteomic analysis of Brucella abortus cell envelope and identification of immunogenic candidate proteins for vaccine development
    • COI: 1:CAS:528:DC%2BD28XntlCjsLY%3D
    • Connolly JP, Comerci D, Alefantis TG, Walz A, Quan M, Chafin R, Grewal P, Mujer CV, Ugalde RA, DelVecchio VG (2006) Proteomic analysis of Brucella abortus cell envelope and identification of immunogenic candidate proteins for vaccine development. Proteomics 6(13):3767–3780
    • (2006) Proteomics , vol.6 , Issue.13 , pp. 3767-3780
    • Connolly, J.P.1    Comerci, D.2    Alefantis, T.G.3    Walz, A.4    Quan, M.5    Chafin, R.6    Grewal, P.7    Mujer, C.V.8    Ugalde, R.A.9    DelVecchio, V.G.10
  • 10
    • 0036736573 scopus 로고    scopus 로고
    • Comparative proteomics of Staphylococcus aureus and the response of methicillin-resistant and methicillin-sensitive strains to Triton X-100
    • COI: 1:CAS:528:DC%2BD38Xnt1elurg%3D
    • Cordwell SJ, Larsen MR, Cole RT, Walsh BJ (2002) Comparative proteomics of Staphylococcus aureus and the response of methicillin-resistant and methicillin-sensitive strains to Triton X-100. Microbiology 148:2765–2781
    • (2002) Microbiology , vol.148 , pp. 2765-2781
    • Cordwell, S.J.1    Larsen, M.R.2    Cole, R.T.3    Walsh, B.J.4
  • 12
    • 3543096871 scopus 로고    scopus 로고
    • Differential gene expression in a Bacteroides fragilis metronidazole-resistant mutant
    • COI: 1:CAS:528:DC%2BD2cXltlyjsbw%3D
    • Diniz CG, Farias LM, Carvalho MA, Rocha ER, Smith CJ (2004) Differential gene expression in a Bacteroides fragilis metronidazole-resistant mutant. J Antimicrob Chemother 54:100–108
    • (2004) J Antimicrob Chemother , vol.54 , pp. 100-108
    • Diniz, C.G.1    Farias, L.M.2    Carvalho, M.A.3    Rocha, E.R.4    Smith, C.J.5
  • 14
    • 0033040986 scopus 로고    scopus 로고
    • Proteomics: translating genomics into products?
    • COI: 1:CAS:528:DyaK1MXhs1Chs7o%3D
    • Dove A (1999) Proteomics: translating genomics into products? Nat Biotechnol 17:233–236
    • (1999) Nat Biotechnol , vol.17 , pp. 233-236
    • Dove, A.1
  • 15
    • 84938071919 scopus 로고    scopus 로고
    • Lipoproteins from Clostridium perfringens and their protective efficacy in mouse model
    • COI: 1:CAS:528:DC%2BC2MXpt1Ois7k%3D
    • Dwivedi P, Alam SI, Kumar O, Kumar RB (2015a) Lipoproteins from Clostridium perfringens and their protective efficacy in mouse model. Infect Genet Evol 34:434–443
    • (2015) Infect Genet Evol , vol.34 , pp. 434-443
    • Dwivedi, P.1    Alam, S.I.2    Kumar, O.3    Kumar, R.B.4
  • 16
    • 84938820870 scopus 로고    scopus 로고
    • Comparative analysis of extractable proteins from Clostridium perfringens type A and type C strains showing varying degree of virulence
    • COI: 1:CAS:528:DC%2BC2MXhs1WjsbrM
    • Dwivedi P, Alam SI, Kumar O, Kumar RB (2015b) Comparative analysis of extractable proteins from Clostridium perfringens type A and type C strains showing varying degree of virulence. Anaerobe 35(Pt B):77–91
    • (2015) Anaerobe , vol.35 , pp. 77-91
    • Dwivedi, P.1    Alam, S.I.2    Kumar, O.3    Kumar, R.B.4
  • 17
    • 31544449974 scopus 로고    scopus 로고
    • Identification of the major outer membrane proteins of Aeromonas salmonicida
    • COI: 1:CAS:528:DC%2BD28XivVSht78%3D
    • Ebanks RO, Goguen M, McKinnon S, Pinto DM, Ross NW (2005) Identification of the major outer membrane proteins of Aeromonas salmonicida. Dis Aquat Organ 68:29–38
    • (2005) Dis Aquat Organ , vol.68 , pp. 29-38
    • Ebanks, R.O.1    Goguen, M.2    McKinnon, S.3    Pinto, D.M.4    Ross, N.W.5
  • 18
    • 84898927577 scopus 로고    scopus 로고
    • Comparative genomics and immunoinformatics approach for the identification of vaccine candidates for enterohemorrhagic Escherichia coli O157:H7
    • García-Angulo VA, Kalita A, Kalita M, Lozano L, Torres AG (2014) Comparative genomics and immunoinformatics approach for the identification of vaccine candidates for enterohemorrhagic Escherichia coli O157:H7. Infect Immun 82(5):2016–2026
    • (2014) Infect Immun , vol.82 , Issue.5 , pp. 2016-2026
    • García-Angulo, V.A.1    Kalita, A.2    Kalita, M.3    Lozano, L.4    Torres, A.G.5
  • 19
    • 84875319728 scopus 로고    scopus 로고
    • Immunogenic and invasive properties of Brucella melitensis 16 M outer membrane protein vaccine candidates identified via a reverse vaccinology approach
    • COI: 1:CAS:528:DC%2BC3sXlsVOntbw%3D
    • Gomez G, Pei J, Mwangi W, Adams LG, Rice-Ficht A, Ficht TA (2013) Immunogenic and invasive properties of Brucella melitensis 16 M outer membrane protein vaccine candidates identified via a reverse vaccinology approach. PLoS One 8(3):e59751
    • (2013) PLoS One , vol.8 , Issue.3 , pp. e59751
    • Gomez, G.1    Pei, J.2    Mwangi, W.3    Adams, L.G.4    Rice-Ficht, A.5    Ficht, T.A.6
  • 20
    • 0035342085 scopus 로고    scopus 로고
    • Antibacterial vaccine design using genomics and proteomics
    • COI: 1:CAS:528:DC%2BD3MXisF2nurk%3D
    • Grandi G (2001) Antibacterial vaccine design using genomics and proteomics. Trends Biotechnol 19:181–188
    • (2001) Trends Biotechnol , vol.19 , pp. 181-188
    • Grandi, G.1
  • 21
    • 77955360252 scopus 로고    scopus 로고
    • Vaxign: the first web-based vaccine design program for reverse vaccinology and applications for vaccine development
    • He Y, Xiang Z, Mobley HL (2010) Vaxign: the first web-based vaccine design program for reverse vaccinology and applications for vaccine development. J Biomed Biotechnol 2010:297505
    • (2010) J Biomed Biotechnol , vol.2010 , pp. 297505
    • He, Y.1    Xiang, Z.2    Mobley, H.L.3
  • 22
    • 44649143912 scopus 로고    scopus 로고
    • Immunoproteomic identification of the hypothetical protein NMB1468 as a novel lipoprotein ubiquitous in Neisseria meningitidis with vaccine potential
    • COI: 1:CAS:528:DC%2BD1cXmvFWktbc%3D
    • Hsu CA, Lin WR, Li JC, Liu YL, Tseng YT, Chang CM, Lee YS, Yang CY (2008) Immunoproteomic identification of the hypothetical protein NMB1468 as a novel lipoprotein ubiquitous in Neisseria meningitidis with vaccine potential. Proteomics 8(10):2115–2125
    • (2008) Proteomics , vol.8 , Issue.10 , pp. 2115-2125
    • Hsu, C.A.1    Lin, W.R.2    Li, J.C.3    Liu, Y.L.4    Tseng, Y.T.5    Chang, C.M.6    Lee, Y.S.7    Yang, C.Y.8
  • 23
    • 20544465685 scopus 로고    scopus 로고
    • Proteomics reveals that proteins expressed during the early stage of Bacillus anthracis infection are potential targets for the development of vaccines and drugs
    • COI: 1:CAS:528:DC%2BD2MXkvFyrsrg%3D
    • Huang CM, Elmets CA, Tang DC, Li F, Yusuf N (2004) Proteomics reveals that proteins expressed during the early stage of Bacillus anthracis infection are potential targets for the development of vaccines and drugs. Genom Proteoms Bioinform 2:143–151
    • (2004) Genom Proteoms Bioinform , vol.2 , pp. 143-151
    • Huang, C.M.1    Elmets, C.A.2    Tang, D.C.3    Li, F.4    Yusuf, N.5
  • 24
    • 33751265985 scopus 로고    scopus 로고
    • Immunoproteome analysis of soluble and membrane proteins of Shigella flexneri 2457T
    • COI: 1:CAS:528:DC%2BD2sXntVams7k%3D
    • Jennison AV, Raqib R, Verma NK (2006) Immunoproteome analysis of soluble and membrane proteins of Shigella flexneri 2457T. World J Gastroenterol 12(41):6683–6688
    • (2006) World J Gastroenterol , vol.12 , Issue.41 , pp. 6683-6688
    • Jennison, A.V.1    Raqib, R.2    Verma, N.K.3
  • 25
    • 84890788467 scopus 로고    scopus 로고
    • Characterization of the in vitro core surface proteome of Mycoplasma mycoides subsp. mycoides, the causative agent of contagious bovine pleuropneumonia
    • COI: 1:CAS:528:DC%2BC3sXhvFyrurbI
    • Krasteva I, Liljander A, Fischer A, Smith DG, Inglis NF, Scacchia M, Pini A, Jores J, Sacchini F (2014) Characterization of the in vitro core surface proteome of Mycoplasma mycoides subsp. mycoides, the causative agent of contagious bovine pleuropneumonia. Vet Microbiol 168(1):116–123
    • (2014) Vet Microbiol , vol.168 , Issue.1 , pp. 116-123
    • Krasteva, I.1    Liljander, A.2    Fischer, A.3    Smith, D.G.4    Inglis, N.F.5    Scacchia, M.6    Pini, A.7    Jores, J.8    Sacchini, F.9
  • 26
    • 77952019246 scopus 로고    scopus 로고
    • Immunoproteomic identification of polyvalent vaccine candidates from Vibrio parahaemolyticus outer membrane proteins
    • COI: 1:CAS:528:DC%2BC3cXislyrtrg%3D
    • Li H, Ye MZ, Peng B, Wu HK, Xu CX, Xiong XP, Wang C, Wang SY, Peng XX (2010) Immunoproteomic identification of polyvalent vaccine candidates from Vibrio parahaemolyticus outer membrane proteins. J Proteome Res 9(5):2573–2583
    • (2010) J Proteome Res , vol.9 , Issue.5 , pp. 2573-2583
    • Li, H.1    Ye, M.Z.2    Peng, B.3    Wu, H.K.4    Xu, C.X.5    Xiong, X.P.6    Wang, C.7    Wang, S.Y.8    Peng, X.X.9
  • 27
    • 8144221393 scopus 로고    scopus 로고
    • Glycolytic enzymes associated with the cell surface of Streptococcus pneumoniae are antigenic in humans and elicit protective immune responses in the mouse
    • COI: 1:CAS:528:DC%2BD2cXhtVaksbrJ
    • Ling E, Feldman G, Portnoi M, Dagan R, Overweg K, Mulholland F, Chalifa-Caspi V, Wells J, Mizrachi-Nebenzahl Y (2004) Glycolytic enzymes associated with the cell surface of Streptococcus pneumoniae are antigenic in humans and elicit protective immune responses in the mouse. Clin Exp Immunol 138(2):290–298
    • (2004) Clin Exp Immunol , vol.138 , Issue.2 , pp. 290-298
    • Ling, E.1    Feldman, G.2    Portnoi, M.3    Dagan, R.4    Overweg, K.5    Mulholland, F.6    Chalifa-Caspi, V.7    Wells, J.8    Mizrachi-Nebenzahl, Y.9
  • 28
    • 84900302152 scopus 로고    scopus 로고
    • Identification of immunoreactive proteins of Streptococcus agalactiae isolated from cultured tilapia in China
    • COI: 1:CAS:528:DC%2BC3sXhvVWgsr%2FO
    • Liu G, Zhang W, Lu C (2013) Identification of immunoreactive proteins of Streptococcus agalactiae isolated from cultured tilapia in China. Pathog Dis 69(3):223–231
    • (2013) Pathog Dis , vol.69 , Issue.3 , pp. 223-231
    • Liu, G.1    Zhang, W.2    Lu, C.3
  • 29
    • 74149091291 scopus 로고    scopus 로고
    • Identification of immunogenic proteins from Burkholderia cepacia secretome using proteomic analysis
    • COI: 1:CAS:528:DC%2BC3cXnt1eltA%3D%3D
    • Mariappan V, Vellasamy KM, Thimma JS, Hashim OH, Vadivelu J (2010) Identification of immunogenic proteins from Burkholderia cepacia secretome using proteomic analysis. Vaccine 28(5):1318–1324
    • (2010) Vaccine , vol.28 , Issue.5 , pp. 1318-1324
    • Mariappan, V.1    Vellasamy, K.M.2    Thimma, J.S.3    Hashim, O.H.4    Vadivelu, J.5
  • 31
    • 84861149869 scopus 로고    scopus 로고
    • Surface proteome of “Mycobacterium avium subsp. hominissuis” during the early stages of macrophage infection
    • COI: 1:CAS:528:DC%2BC38XmsVKmsbw%3D
    • McNamara M, Tzeng SC, Maier C, Zhang L, Bermudez LE (2012) Surface proteome of “Mycobacterium avium subsp. hominissuis” during the early stages of macrophage infection. Infect Immun 80(5):1868–1880
    • (2012) Infect Immun , vol.80 , Issue.5 , pp. 1868-1880
    • McNamara, M.1    Tzeng, S.C.2    Maier, C.3    Zhang, L.4    Bermudez, L.E.5
  • 32
    • 34548479248 scopus 로고    scopus 로고
    • Streptococcus pneumoniae surface-exposed glutamyl trna synthetase, a putative adhesin, is able to induce a partially protective immune response in mice
    • Mizrachi Nebenzahl Y, Bernstein A, Portnoi M, Shagan M, Rom S, Porgador A, Dagan R (2007) Streptococcus pneumoniae surface-exposed glutamyl trna synthetase, a putative adhesin, is able to induce a partially protective immune response in mice. J Infect Dis 196:945–953
    • (2007) J Infect Dis , vol.196 , pp. 945-953
    • Mizrachi Nebenzahl, Y.1    Bernstein, A.2    Portnoi, M.3    Shagan, M.4    Rom, S.5    Porgador, A.6    Dagan, R.7
  • 33
    • 0036259796 scopus 로고    scopus 로고
    • Proteomic analysis of differentially expressed Chlamydia pneumoniae genes during persistent infection of HEp-2 cells
    • COI: 1:CAS:528:DC%2BD38XktFGitbo%3D
    • Molestina RE, Klein JB, Miller RD, Pierce WH, Ramirez JA, Summersgill JT (2002) Proteomic analysis of differentially expressed Chlamydia pneumoniae genes during persistent infection of HEp-2 cells. Infect Immun 70:2976–2981
    • (2002) Infect Immun , vol.70 , pp. 2976-2981
    • Molestina, R.E.1    Klein, J.B.2    Miller, R.D.3    Pierce, W.H.4    Ramirez, J.A.5    Summersgill, J.T.6
  • 36
    • 84926154115 scopus 로고    scopus 로고
    • Identification of putative vaccine candidates against Helicobacter pylori exploiting exoproteome and secretome: a reverse vaccinology based approach
    • COI: 1:CAS:528:DC%2BC2MXlsVOqsr8%3D
    • Naz A, Awan FM, Obaid A, Muhammad SA, Paracha RZ, Ahmad J, Ali A (2015) Identification of putative vaccine candidates against Helicobacter pylori exploiting exoproteome and secretome: a reverse vaccinology based approach. Infect Genet Evol 32:280–291
    • (2015) Infect Genet Evol , vol.32 , pp. 280-291
    • Naz, A.1    Awan, F.M.2    Obaid, A.3    Muhammad, S.A.4    Paracha, R.Z.5    Ahmad, J.6    Ali, A.7
  • 38
    • 78650468000 scopus 로고    scopus 로고
    • Immunoproteomic analysis and identification of novel immunogenic proteins from Vibrio harveyi
    • COI: 1:CAS:528:DC%2BC3cXhsFaiurjJ
    • Pang HY, Li Y, Wu ZH, Jian JC, Lu YS, Cai SH (2010) Immunoproteomic analysis and identification of novel immunogenic proteins from Vibrio harveyi. J Appl Microbiol 109(5):1800–1809
    • (2010) J Appl Microbiol , vol.109 , Issue.5 , pp. 1800-1809
    • Pang, H.Y.1    Li, Y.2    Wu, Z.H.3    Jian, J.C.4    Lu, Y.S.5    Cai, S.H.6
  • 39
    • 84957621864 scopus 로고    scopus 로고
    • Immunoproteomics-based analysis of the immunocompetent serological response to Lomentospora prolificans
    • COI: 1:CAS:528:DC%2BC28XhvVyitA%3D%3D
    • Pellon A, Ramirez-Garcia A, Buldain I, Antoran A, Rementeria A, Hernando FL (2016) Immunoproteomics-based analysis of the immunocompetent serological response to Lomentospora prolificans. J Proteome Res 15(2):595–607
    • (2016) J Proteome Res , vol.15 , Issue.2 , pp. 595-607
    • Pellon, A.1    Ramirez-Garcia, A.2    Buldain, I.3    Antoran, A.4    Rementeria, A.5    Hernando, F.L.6
  • 40
    • 0142147304 scopus 로고    scopus 로고
    • Reverse vaccinology and genomics
    • COI: 1:CAS:528:DC%2BD3sXotlWqtLg%3D
    • Rappuoli R, Covacci A (2003) Reverse vaccinology and genomics. Science 302:602
    • (2003) Science , vol.302 , pp. 602
    • Rappuoli, R.1    Covacci, A.2
  • 43
    • 84867397072 scopus 로고    scopus 로고
    • Developing vaccines in the era of genomics: a decade of reverse vaccinology
    • Seib KL, Zhao X, Rappuoli R (2012) Developing vaccines in the era of genomics: a decade of reverse vaccinology. Clin Microbiol Infect 5:109–116
    • (2012) Clin Microbiol Infect , vol.5 , pp. 109-116
    • Seib, K.L.1    Zhao, X.2    Rappuoli, R.3
  • 44
    • 77956641352 scopus 로고    scopus 로고
    • Comparative proteomic analysis of extracellular proteins of Clostridium perfringens type A and type C strains
    • COI: 1:CAS:528:DC%2BC3cXhtF2qsbbM
    • Sengupta N, Alam SI, Kumar B, Kumar RB, Gautam V, Kumar S, Singh L (2010) Comparative proteomic analysis of extracellular proteins of Clostridium perfringens type A and type C strains. Infect Immun 78:3957–3968
    • (2010) Infect Immun , vol.78 , pp. 3957-3968
    • Sengupta, N.1    Alam, S.I.2    Kumar, B.3    Kumar, R.B.4    Gautam, V.5    Kumar, S.6    Singh, L.7
  • 45
    • 84946422885 scopus 로고    scopus 로고
    • Growth phase-dependent composition of the Helicobacter pylori exoproteome
    • COI: 1:CAS:528:DC%2BC2MXhsFKqsb3L
    • Snider CA, Voss BJ, McDonald WH, Cover TL (2016) Growth phase-dependent composition of the Helicobacter pylori exoproteome. J Proteom 130:94–107
    • (2016) J Proteom , vol.130 , pp. 94-107
    • Snider, C.A.1    Voss, B.J.2    McDonald, W.H.3    Cover, T.L.4
  • 46
    • 84868695189 scopus 로고    scopus 로고
    • MHC class I-presented T cell epitopes identified by immunoproteomics analysis are targets for a cross reactive influenza-specific T cell response
    • COI: 1:CAS:528:DC%2BC38XhslehsrbE
    • Testa JS, Shetty V, Hafner J, Nickens Z, Kamal S, Sinnathamby G, Philip R (2012) MHC class I-presented T cell epitopes identified by immunoproteomics analysis are targets for a cross reactive influenza-specific T cell response. PLoS One 7(11):e48484. doi:10.1371/journal.pone.0048484
    • (2012) PLoS One , vol.7 , Issue.11 , pp. e48484
    • Testa, J.S.1    Shetty, V.2    Hafner, J.3    Nickens, Z.4    Kamal, S.5    Sinnathamby, G.6    Philip, R.7
  • 47
    • 17844401762 scopus 로고    scopus 로고
    • Comparative proteome analysis of secretory proteins from pathogenic and non-pathogenic Listeria species
    • COI: 1:CAS:528:DC%2BD2MXktVWjs7c%3D
    • Trost M, Wehmhöner D, Kärst U, Dieterich G, Wehland J, Jänsch L (2005) Comparative proteome analysis of secretory proteins from pathogenic and non-pathogenic Listeria species. Proteomics 5:1544–1557
    • (2005) Proteomics , vol.5 , pp. 1544-1557
    • Trost, M.1    Wehmhöner, D.2    Kärst, U.3    Dieterich, G.4    Wehland, J.5    Jänsch, L.6
  • 48
    • 84896865605 scopus 로고    scopus 로고
    • Identification of vaccine antigens using integrated proteomic analyses of surface immunogens from serogroup B Neisseria meningitidis
    • COI: 1:CAS:528:DC%2BC2cXks1ajsrY%3D
    • Tsolakos N, Brookes C, Taylor S, Gorringe A, Tang CM, Feavers IM, Wheeler JX (2014) Identification of vaccine antigens using integrated proteomic analyses of surface immunogens from serogroup B Neisseria meningitidis. J Proteom 101:63–76
    • (2014) J Proteom , vol.101 , pp. 63-76
    • Tsolakos, N.1    Brookes, C.2    Taylor, S.3    Gorringe, A.4    Tang, C.M.5    Feavers, I.M.6    Wheeler, J.X.7
  • 49
    • 33749035486 scopus 로고    scopus 로고
    • NERVE: new enhanced reverse vaccinology environment
    • Vivona S, Bernante F, Filippini F (2006) NERVE: new enhanced reverse vaccinology environment. BMC Biotechnol 6:35
    • (2006) BMC Biotechnol , vol.6 , pp. 35
    • Vivona, S.1    Bernante, F.2    Filippini, F.3
  • 50
    • 67650177056 scopus 로고    scopus 로고
    • Identification of uropathogenic Escherichia coli surface proteins by shotgun proteomics
    • COI: 1:CAS:528:DC%2BD1MXoslCmsrk%3D
    • Walters MS, Mobley HL (2009) Identification of uropathogenic Escherichia coli surface proteins by shotgun proteomics. J Microbiol Methods 78(2):131–135
    • (2009) J Microbiol Methods , vol.78 , Issue.2 , pp. 131-135
    • Walters, M.S.1    Mobley, H.L.2
  • 51
    • 77950823575 scopus 로고    scopus 로고
    • Bacterial proteomics and identification of potential vaccine targets
    • COI: 1:CAS:528:DC%2BC3cXksVCrsr0%3D
    • Walters MS, Mobley HL (2010) Bacterial proteomics and identification of potential vaccine targets. Expert Rev Proteom 7:181–184
    • (2010) Expert Rev Proteom , vol.7 , pp. 181-184
    • Walters, M.S.1    Mobley, H.L.2
  • 53
    • 80052704944 scopus 로고    scopus 로고
    • Differential secretomics of Streptococcus pyogenes reveals a novel peroxide regulator (PerR)-regulated extracellular virulence factor mitogen factor 3 (MF3)
    • Wen YT, Tsou CC, Kuo HT, Wang JS, Wu JJ, Liao PC (2011) Differential secretomics of Streptococcus pyogenes reveals a novel peroxide regulator (PerR)-regulated extracellular virulence factor mitogen factor 3 (MF3). Mol Cell Proteom 10(M110):007013
    • (2011) Mol Cell Proteom , vol.10 , Issue.M110 , pp. 007013
    • Wen, Y.T.1    Tsou, C.C.2    Kuo, H.T.3    Wang, J.S.4    Wu, J.J.5    Liao, P.C.6
  • 54
    • 84885051319 scopus 로고    scopus 로고
    • Proteomic tools for environmental microbiology-a roadmap from sample preparation to protein identification and quantification
    • Wöhlbrand L, Trautwein K, Rabus R (2013) Proteomic tools for environmental microbiology-a roadmap from sample preparation to protein identification and quantification. Proteomics 13:2700–2730
    • (2013) Proteomics , vol.13 , pp. 2700-2730
    • Wöhlbrand, L.1    Trautwein, K.2    Rabus, R.3
  • 55
    • 20644450358 scopus 로고    scopus 로고
    • Proteomic analysis of cell surface proteins from Clostridium difficile
    • COI: 1:CAS:528:DC%2BD2MXlsFCmsr8%3D
    • Wright A, Wait R, Begum S, Crossett B, Nagy J, Brown K, Fairweather N (2005) Proteomic analysis of cell surface proteins from Clostridium difficile. Proteomics 5:2443–2452
    • (2005) Proteomics , vol.5 , pp. 2443-2452
    • Wright, A.1    Wait, R.2    Begum, S.3    Crossett, B.4    Nagy, J.5    Brown, K.6    Fairweather, N.7
  • 56
    • 33845305461 scopus 로고    scopus 로고
    • In silico and microarray-based genomic approaches to identifying potential vaccine candidates against Leptospira interrogans
    • Yang HL, Zhu YZ, Qin JH, He P, Jiang XC, Zhao GP, Guo XK (2006) In silico and microarray-based genomic approaches to identifying potential vaccine candidates against Leptospira interrogans. BMC Genom 16(7):293
    • (2006) BMC Genom , vol.16 , Issue.7 , pp. 293
    • Yang, H.L.1    Zhu, Y.Z.2    Qin, J.H.3    He, P.4    Jiang, X.C.5    Zhao, G.P.6    Guo, X.K.7
  • 57
    • 82455181876 scopus 로고    scopus 로고
    • Immunoproteomic analysis of Brucella melitensis and identification of a new immunogenic candidate protein for the development of brucellosis subunit vaccine
    • COI: 1:CAS:528:DC%2BC3MXhtlyjtL%2FF
    • Yang Y, Wang L, Yin J, Wang X, Cheng S, Lang X, Wang X, Qu H, Sun C, Wang J, Zhang R (2011) Immunoproteomic analysis of Brucella melitensis and identification of a new immunogenic candidate protein for the development of brucellosis subunit vaccine. Mol Immunol 49(1–2):175–184
    • (2011) Mol Immunol , vol.49 , Issue.1-2 , pp. 175-184
    • Yang, Y.1    Wang, L.2    Yin, J.3    Wang, X.4    Cheng, S.5    Lang, X.6    Wang, X.7    Qu, H.8    Sun, C.9    Wang, J.10    Zhang, R.11
  • 58
    • 84884768623 scopus 로고    scopus 로고
    • Extracellular proteome analysis of Leptospira interrogans serovar Lai
    • COI: 1:CAS:528:DC%2BC3sXhsFSmsbfN
    • Zeng L, Zhang Y, Zhu Y, Yin H, Zhuang X, Zhu W, Guo X, Qin J (2013) Extracellular proteome analysis of Leptospira interrogans serovar Lai. OMICS 17(10):527–535
    • (2013) OMICS , vol.17 , Issue.10 , pp. 527-535
    • Zeng, L.1    Zhang, Y.2    Zhu, Y.3    Yin, H.4    Zhuang, X.5    Zhu, W.6    Guo, X.7    Qin, J.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.