Bacillus anthracis secretome time course under host-simulated conditions and identification of immunogenic proteins

Proteome Science

Volumn 5, Issue , 2007, Pages

  Walz, Alexander ^a   Mujer, Cesar V ^a,d   Connolly, Joseph P ^a   Alefantis, Tim ^a   Chafin, Ryan ^a   Dake, Clarissa ^a   Whittington, Jessica ^a   Kumar, Srikanta P ^b   Khan, Akbar S ^c   DelVecchio, Vito G ^a  

^a Vital Probes Inc   (United States)

^b BAE SYSTEMS   (United States)

^c DEFENSE THREAT REDUCTION AGENCY   (United States)

^d Calvert Laboratories Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRAX VACCINE; CELL PROTEIN; CYTOPLASM PROTEIN; ENOLASE; MEMBRANE PROTEIN; PROTECTIVE AGENT; SCLEROPROTEIN; TRANSKETOLASE;

ALGORITHM; ANTHRAX; ARTICLE; BACILLUS ANTHRACIS; BACTERIAL GROWTH; BACTERIAL STRAIN; CELLULAR DISTRIBUTION; COMPUTER PROGRAM; DISEASE SEVERITY; GENETIC VARIABILITY; HUMAN; IMMUNOGENICITY; LIQUID CHROMATOGRAPHY; MARKER GENE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; PATHOGENESIS; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN SECRETION; TANDEM MASS SPECTROMETRY; TWO DIMENSIONAL GEL ELECTROPHORESIS;

BACILLUS ANTHRACIS;

EID: 34548191584     PISSN: None     EISSN: 14775956     Source Type: Journal    
DOI: 10.1186/1477-5956-5-11     Document Type: Article

References (38)

1. Mock M Fouet A Anthrax Annu Rev Microbiol 2001, 55:647-671. 10.1146/ annurev.micro.55.1.647 11544370
2. Makino S Uchida I Terakado N Sasakawa C Yoshikawa M Molecular characterization and protein analysis of the cap region, which is essential for encapsulation in Bacillus anthracis J Bacteriol 1989, 171:722-730. 209657 2536679
3. Uchida I Makino S Sasakawa C Yoshikawa M Sugimoto C Terakado N Identification of a novel gene, dep, associated with depolymerization of the capsular polymer in Bacillus anthracis Mol Microbiol 1993, 9:487-496. 10.1111/j.1365-2958.1993.tb01710.x 8105361
4. Ristroph JD Ivins BE Elaboration of Bacillus anthracis antigens in a new, defined culture medium Infect Immun 1983, 39:483-486. 347970 6401697
5. Sirard JC Mock M Fouet A The three Bacillus anthracis toxin genes are coordinately regulated by bicarbonate and temperature J Bacteriol 1994, 176:5188-5192. 196368 8051039
6. Chitlaru T Gat O Gozlan Y Ariel N Shafferman A Differential proteomic analysis of the Bacillus anthracis secretome: Distinct plasmid and chromosome CO2-dependent cross talk mechanisms modulate extracellular proteolytic activities J Bacteriol 2006, 188:3551-3571. 1482852 16672610 10.1128/JB.188.10.3551-3571.2006
7. Antelmann H Williams RC Miethke M Wipat A Albrecht D Harwood CR Hecker M The extracellular and cytoplasmic proteomes of the non-virulent Bacillus anthracis strain UM23C1-2 Proteomics 2005, 5:3684-3695. 10.1002/ pmic.200401218 16121336
8. Gohar M Gilois N Graveline R Garreau C Sanchis V Lereclus D A comparative study of Bacillus cereus, Bacillus thuringiensis and Bacillus anthracis extracellular proteomes Proteomics 2005, 5:3696-3711. 10.1002/pmic.200401225 16167365
9. Lamonica JM Wagner M Eschenbrenner M Williams LE Miller TL Patra G Delvecchio VG Comparative secretome analyses of three Bacillus anthracis strains with variant plasmid contents Infect Immun 2005, 73:3646-3658. 1111850 15908394 10.1128/IAI.73.6.3646-3658.2005
10. Gohar M Okstad OA Gilois N Sanchis V Kolsto AB Lereclus D Two-dimensional electrophoresis analysis of the extracellular proteome of Bacillus cereus reveals the importance of the PlcR regulon Proteomics 2002, 2:784-791. 10.1002/ 1615-9861(200206)2:6<784::AID-PROT784>3.0.CO;2-R 12112862
11. Agaisse H Gominet M Okstad OA Kolsto AB Lereclus D PlcR is a pleiotropic regulator of extracellular virulence factor gene expression in Bacillus thuringiensis Mol Microbiol 1999, 32:1043-1053. 10.1046/ j.1365-2958.1999.01419.x 10361306
12. Mignot T Mock M Robichon D Landier A Lereclus D Fouet A The incompatibility between the PlcR- and AtxA-controlled regulons may have selected a nonsense mutation in Bacillus anthracis Mol Microbiol 2001, 42:1189-1198. 10.1046/j.1365-2958.2001.02692.x 11886551
13. Schmidt F Donahoe S Hagens K Mattow J Schaible UE Kaufmann SH Aebersold R Jungblut PR Complementary analysis of the Mycobacterium tuberculosis proteome by two-dimensional electrophoresis and isotope-coded affinity tag technology Mol Cell Proteomics 2004, 3:24-42. 10.1074/ mcp.M300074-MCP200 14557599
14. Connolly JP Comerci D Alefantis TG Walz A Quan M Chafin R Grewal P Mujer CV Ugalde RA Delvecchio VG Proteomic analysis of Brucella abortus cell envelope and identification of immunogenic candidate proteins for vaccine development Proteomics 2006, 6:3767-3780. 10.1002/pmic.200500730 16739129
15. The Institute for Genomic Research 2007 [http://www.tigr.org].
16. Bendtsen JD Nielsen H Von HG Brunak S Improved prediction of signal peptides: SignalP 3.0 J Mol Biol 2004, 340:783-795. 10.1016/ j.jmb.2004.05.028 15223320
17. Nielsen H Engelbrecht J Brunak S Von HG Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites Protein Eng 1997, 10:1-6. 10.1093/protein/10.1.1 9051728
18. Juncker AS Willenbrock H Von HG Brunak S Nielsen H Krogh A Prediction of lipoprotein signal peptides in Gram-negative bacteria Protein Sci 2003, 12:1652-1662. 10.1110/ps.0303703 12876315
19. Krogh A Larsson B Von HG Sonnhammer EL Predicting transmembrane protein topology with a hidden Markov model: Application to complete genomes J Mol Biol 2001, 305:567-580. 10.1006/jmbi.2000.4315 11152613
20. Hulo N Bairoch A Bulliard V Cerutti L de CE Langendijk-Genevaux PS Pagni M Sigrist CJ The PROSITE database Nucleic Acids Res 2006, 34:D227-D230. 1347426 16381852 10.1093/nar/gkj063
21. Bendtsen JD Jensen LJ Blom N Von HG Brunak S Feature-based prediction of non-classical and leaderless protein secretion Protein Eng Des Sel 2004, 17:349-356. 10.1093/protein/gzh037 15115854
22. Nakai K Horton P PSORT: A program for detecting sorting signals in proteins and predicting their subcellular localization Trends Biochem Sci 1999, 24:34-36. 10.1016/S0968-0004(98)01336-X 10087920
23. Binnewies TT Bendtsen JD Hallin PF Nielsen N Wassenaar TM Pedersen MB Klemm P Ussery DW Genome Update: Protein secretion systems in 225 bacterial genomes Microbiology 2005, 151:1013-1016. 10.1099/ mic.0.27966-0 15817770
24. Ezzell JW Jr. Abshire TG Serum protease cleavage of Bacillus anthracis protective antigen J Gen Microbiol 1992, 138:543-549. 1593265
25. Zomber G Reuveny S Garti N Shafferman A Elhanany E Effects of spontaneous deamidation on the cytotoxic activity of the Bacillus anthracis protective antigen J Biol Chem 2005, 280:39897-39906. 10.1074/ jbc.M508569200 16188881
26. Liu H Bergman NH Thomason B Shallom S Hazen A Crossno J Rasko DA Ravel J Read TD Peterson SN Yates J III Hanna PC Formation and composition of the Bacillus anthracis endospore J Bacteriol 2004, 186:164-178. 303457 14679236 10.1128/JB.186.1.164-178.2004
27. Delvecchio VG Connolly JP Alefantis TG Walz A Quan MA Patra G Ashton JM Whittington JT Chafin RD Liang X Grewal P Khan AS Mujer CV Proteomic profiling and identification of immunodominant spore antigens of Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis Appl Environ Microbiol 2006, 72:6355-6363. 1563598 16957262 10.1128/ AEM.00455-06
28. Mignot T Mesnage S Couture-Tosi E Mock M Fouet A Developmental switch of S-layer protein synthesis in Bacillus anthracis Mol Microbiol 2002, 43:1615-1627. 10.1046/j.1365-2958.2002.02852.x 11952909
29. Whiting GC Rijpkema S Adams T Corbel MJ Characterisation of adsorbed anthrax vaccine by two-dimensional gel electrophoresis Vaccine 2004, 22:4245-4251. 10.1016/j.vaccine.2004.04.036 15474715
30. Chitlaru T Gat O Grosfeld H Inbar I Gozlan Y Shafferman A Identification of In Vivo-Expressed Immunogenic Proteins by Serological Proteome Analysis of the Bacillus anthracis Secretome Infect Immun 2007, 75:2841-2852. 10.1128/IAI.02029-06 17353282
31. Chitlaru T Ariel N Zvi A Lion M Velan B Shafferman A Elhanany E Identification of chromosomally encoded membranal polypeptides of Bacillus anthracis by a proteomic analysis: Prevalence of proteins containing S-layer homology domains Proteomics 2004, 4:677-691. 10.1002/ pmic.200300575 14997491
32. Mesnage S Tosi-Couture E Mock M Fouet A The S-layer homology domain as a means for anchoring heterologous proteins on the cell surface of Bacillus anthracis J Appl Microbiol 1999, 87:256-260. 10.1046/ j.1365-2672.1999.00880.x 10475961
33. Sara M Sleytr UB S-Layer proteins J Bacteriol 2000, 182:859-868. 94357 10648507 10.1128/JB.182.4.859-868.2000
34. Lei B Mackie S Lukomski S Musser JM Identification and immunogenicity of group A Streptococcus culture supernatant proteins Infect Immun 2000, 68:6807-6818. 97784 11083799 10.1128/IAI.68.12.6807-6818.2000
35. Jungblut PR Schaible UE Mollenkopf HJ Zimny-Arndt U Raupach B Mattow J Halada P Lamer S Hagens K Kaufmann SH Comparative proteome analysis of Mycobacterium tuberculosis and Mycobacterium bovis BCG strains: Towards functional genomics of microbial pathogens Mol Microbiol 1999, 33:1103-1117. 10.1046/j.1365-2958.1999.01549.x 10510226
36. Rosenkrands I Weldingh K Jacobsen S Hansen CV Florio W Gianetri I Andersen P Mapping and identification of Mycobacterium tuberculosis proteins by two-dimensional gel electrophoresis, microsequencing and immunodetection Electrophoresis 2000, 21:935-948. 10.1002/ (SICI)1522-2683(20000301)21:5<935::AID-ELPS935>3.0.CO;2-P 10768780
37. Antelmann H Tjalsma H Voigt B Ohlmeier S Bron S van Dijl JM Hecker M A proteomic view on genome-based signal peptide predictions Genome Res 2001, 11:1484-1502. 10.1101/gr.182801 11544192
38. Towbin H Staehelin T Gordon J Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications Proc Natl Acad Sci U S A 1979, 76:4350-4354. 411572 388439 10.1073/pnas.76.9.4350