Differential secretomics of Streptococcus pyogenes reveals a novel peroxide regulator (PerR)-regulated extracellular virulence factor mitogen factor3 (MF3)

Molecular and Cellular Proteomics

Volumn 10, Issue 9, 2011, Pages

  Wen, Yao Tseng ^a   Tsou, Chih Cheng ^a   Kuo, Hsin Tzu ^a   Wang, Jie Siou ^a   Wu, Jiunn Jong ^a   Liao, Pao Chi ^a,b  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GENE PRODUCT; MITOGEN FACTOR 3; MITOGENIC AGENT; PEROXIDE; PEROXIDE REGULATOR; PROTEINASE INHIBITOR; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; DEOXYRIBONUCLEASE; MF3 PROTEIN, S PYOGENES; PEROXIDE REPRESSOR PROTEINS; REPRESSOR PROTEIN; VIRULENCE FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CONTROLLED STUDY; DOWN REGULATION; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; GENE EXPRESSION; GENE SEQUENCE; HOST PATHOGEN INTERACTION; IMMUNOBLOTTING; LIQUID CHROMATOGRAPHY; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEOMICS; STREPTOCOCCUS PYOGENES; TANDEM MASS SPECTROMETRY; TWO DIMENSIONAL GEL ELECTROPHORESIS; UPREGULATION; WILD TYPE; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; CULTURE MEDIUM; GEL MOBILITY SHIFT ASSAY; GENE DELETION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; METHODOLOGY; MICROBIOLOGY; MORTALITY; PATHOGENICITY; PROTEIN BINDING; SECRETION; STREPTOCOCCUS INFECTION; SURVIVAL RATE;

STREPTOCOCCUS PYOGENES;

ANIMALS; BACTERIAL PROTEINS; CULTURE MEDIA, CONDITIONED; DEOXYRIBONUCLEASES; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FEMALE; GENE DELETION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, BACTERIAL; HOST-PATHOGEN INTERACTIONS; HUMANS; MICE; MICE, INBRED BALB C; PEROXIDES; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEOMICS; REPRESSOR PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS PYOGENES; SURVIVAL RATE; VIRULENCE FACTORS;

EID: 80052704944     PISSN: 15359476     EISSN: 15359484     Source Type: Journal    
DOI: 10.1074/mcp.M110.007013     Document Type: Article

References (34)

1. O'Brien, K. L., Beall, B., Barrett, N. L., Cieslak, P. R., Reingold, A., Farley, M. M., Danila, R., Zell, E. R., Facklam, R., Schwartz, B., and Schuchat, A. (2002) Epidemiology of invasive group a streptococcus disease in the United States, 1995-1999. Clin. Inf. Dis. 35, 268-276 (Pubitemid 34800274)
2. Cunningham, M. W. (2000) Pathogenesis of group A streptococcal infections. Clin. Microbiol. Rev. 13, 470-511
3. Agaisse, H., Gominet, M., Okstad, O. A., Kolstø, A. B., and Lereclus, D. (1999) PlcR is a pleiotropic regulator of extracellular virulence factor gene expression in Bacillus thuringiensis. Mol. Microbiol. 32, 1043-1053 (Pubitemid 29255770)
4. Chaussee, M. S., Watson, R. O., Smoot, J. C., and Musser, J. M. (2001) Identification of Rgg-regulated exoproteins of Streptococcus pyogenes. Infect. Immun. 69, 822-831 (Pubitemid 32109545)
5. Walker, M. J., Hollands, A., Sanderson-Smith, M. L., Cole, J. N., Kirk, J. K., Henningham, A., McArthur, J. D., Dinkla, K., Aziz, R. K., Kansal, R. G., Simpson, A. J., Buchanan, J. T., Chhatwal, G. S., Kotb, M., and Nizet, V. (2007) DNase Sda1 provides selection pressure for a switch to invasive group A streptococcal infection. Nat. Med. 13, 981-985 (Pubitemid 47222039)
6. Thulin, P., Johansson, L., Low, D. E., Gan, B. S., Kotb, M., McGeer, A., and Norrby-Teglund, A. (2006) Viable group A streptococci in macrophages during acute soft tissue infection. PLoS. Med. 3, 371-379
7. Darenberg, J., Luca-Harari, B., Jasir, A., Sandgren, A., Pettersson, H., Schalen, C., Norgren, M., Romanus, V., Norrby-Teglund, A., and Normark, B. H. (2007) Molecular and clinical characteristics of invasive group A streptococcal infection in Sweden. Clin. Infect. Diseases 45, 450-458 (Pubitemid 47204461)
8. Johansson, B. P., Levander, F., Von Pawel-Rammingen, U., Berggård, T., Björck, L., and James, P. (2005) The protein expression of Streptococcus pyogenes is significantly influenced by human plasma. J. Proteome Res. 4, 2302-2311 (Pubitemid 41814300)
9. Cole, J. N., McArthur, J. D., McKay, F. C., Sanderson-Smith, M. L., Cork, A. J., Ranson, M., Rohde, M., Itzek, A., Sun, H., Ginsburg, D., Kotb, M., Nizet, V., Chhatwal, G. S., and Walker, M. J. (2006) Trigger for group A streptococcal M1T1 invasive disease. FASEB J. 20, 1745-1747
10. Kazmi, S. U., Kansal, R., Aziz, R. K., Hooshdaran, M., Norrby-Teglund, A., Low, D. E., Halim, A. B., and Kotb, M. (2001) Reciprocal, temporal expression of SpeA and SpeB by invasive M1T1 group a streptococcal isolates in vivo. Infect. Immun. 69, 4988-4995 (Pubitemid 32674482)
11. Gibson, C. M., Mallett, T. C., Claiborne, A., and Caparon, M. G. (2000) Contribution of NADH oxidase to aerobic metabolism of Streptococcus pyogenes. J. Bacteriol. 182, 448-455 (Pubitemid 30030130)
12. Ricci, S., Janulczyk, R., and Björck, L. (2002) The regulator PerR is involved in oxidative stress response and iron homeostasis and is necessary for full virulence of Streptococcus pyogenes. Infect. Immun. 70, 4968-4976
13. Brenot, A., King, K. Y., and Caparon, M. G. (2005) The PerR regulon in peroxide resistance and virulence of Streptococcus pyogenes. Mol. Microbiol. 55, 221-234 (Pubitemid 40127898)
14. Gryllos, I., Grifantini, R., Colaprico, A., Cary, M. E., Hakansson, A., Carey, D. W., Suarez-Chavez, M., Kalish, L. A., Mitchell, P. D., White, G. L., and Wessels, M. R. (2008) PerR confers phagocytic killing resistance and allows pharyngeal colonization by group A Streptococcus. PLoS Pathog. 4, 1-13
15. Becher, D., Hempel, K., Sievers, S., Zuhlke, D., Pane-Farre, J., Otto, A., Fuchs, S., Albrecht, D., Bernhardt, J., Engelmann, S., Volker, U., Van Dijl, J. M., and Hecker, M. (2009) A proteomic view of an important human pathogen - Towards the quantification of the entire Staphylococcus aureus proteome. PLoS ONE 4, 1-12
16. Mariappan, V., Vellasamy, K. M., Thimma, J. S., Hashim, O. H., and Vadivelu, J. (2010) Identification of immunogenic proteins from Burkholderia cepacia secretome using proteomic analysis. Vaccine 28, 1318-1324
17. Trost, M., Wehmhöner, D., Kärst, U., Dieterich, G., Wehland, J., and Jänsch, L. (2005) Comparative proteome analysis of secretory proteins from pathogenic and nonpathogenic Listeria species. Proteomics 5, 1544-1557 (Pubitemid 40593263)
18. Backert, S., Gressmann, H., Kwok, T., Zimny-Arndt, U., König, W., Jungblut, P. R., and Meyer, T. F. (2005) Gene expression and protein profiling of AGS gastric epithelial cells upon infection with Helicobacter pylori. Proteomics 5, 3902-3918 (Pubitemid 41502487)
19. Ying, T., Wang, H., Li, M., Wang, J., Wang, J., Shi, Z., Feng, E., Liu, X., Su, G., Wei, K., Zhang, X., Huang, P., and Huang, L. (2005) Immunoproteomics of outer membrane proteins and extracellular proteins of Shigella flexneri 2a 2457T. Proteomics 5, 4777-4793 (Pubitemid 43016899)
20. Xu, C., Wang, S., Ren, H., Lin, X., Wu, L., and Peng, X. (2005) Proteomic analysis on the expression of outer membrane proteins of Vibrio alginolyticus at different sodium concentrations. Proteomics 5, 3142-3152 (Pubitemid 41176482)
21. Tsou, C. C., Chiang-Ni, C., Lin, Y. S., Chuang, W. J., Lin, M. T., Liu, C. C., and Wu, J. J. (2010) Oxidative stress and metal ions regulate a ferritinlike gene, dpr, in Streptococcus pyogenes. Int. J. Med. Microbiol. 300, 259-264
22. Washburn, M. P., Wolters, D., and Yates, J. R., 3rd. (2001) Large-scale analysis of the yeast proteome by multidimensional protein identification technology. Nat. Biotechnol. 19, 242-247 (Pubitemid 32220565)
23. Kuo, C. F., Wu, J. J., Lin, K. Y., Tsai, P. J., Lee, S. C., Jin, Y. T., Lei, H. Y., and Lin, Y. S. (1998) Role of streptococcal pyrogenic exotoxin B in the mouse model of group A streptococcal infection. Infect. Immun. 66, 3931-3935
24. Mulcahy, H., Charron-Mazenod, L., and Lewenza, S. (2010) Pseudomonas aeruginosa produces an extracellular deoxyribonuclease that is required for utilization of DNA as a nutrient source. Environ. Microbiol. 12, 1621-1629
25. Lyon, W. R., Gibson, C. M., and Caparon, M. G. (1998) A role for trigger factor and an rgg-like regulator in the transcription, secretion and processing of the cysteine proteinase of Streptococcus pyogenes. EMBO J. 17, 6263-6275 (Pubitemid 28497799)
26. Olsen, R. J., and Musser, J. M. (2010) Molecular pathogenesis of necrotizing fasciitis. Ann. Rev. Pathol. 5, 1-31
27. Minodier, P., Bidet, P., Rallu, F., Tapiero, B., Bingen, E., and Ovetchkine, P. (2009) Clinical and microbiologic characteristics of group A streptococcal necrotizing fasciitis in children. Pediatr. Infect. Dis. J. 28, 541-543
28. Tanaka, M., Hasegawa, T., Okamoto, A., Torii, K., and Ohta, M. (2005) Effect of antibiotics on group A Streptococcus exoprotein production analyzed by two-dimensional gel electrophoresis. Antimicrob. Agents Chemother. 49, 88-96 (Pubitemid 40065777)
29. Nakamura, T., Hasegawa, T., Torii, K., Hasegawa, Y., Shimokata, K., and Ohta, M. (2004) Two-dimensional gel electrophoresis analysis of the abundance of virulent exoproteins of group A streptococcus caused by environmental changes. Arch. Microbiol. 181, 74-81 (Pubitemid 38161239)
30. Shelburne, S. A., 3rd, Sumby, P., Sitkiewicz, I., Okorafor, N., Granville, C., Patel, P., Voyich, J., Hull, R., DeLeo, F. R., and Musser, J. M. (2006) Maltodextrin utilization plays a key role in the ability of group A Streptococcus to colonize the oropharynx. Infect. Immun. 74, 4605-4614 (Pubitemid 44157248)
31. Hasegawa, T., Torii, K., Hashikawa, S., Iinuma, Y., and Ohta, M. (2002) Cloning and characterization of two novel DNases from Streptococcus pyogenes. Arch. Microbiol. 177, 451-456 (Pubitemid 34591646)
32. Péant, B., and LaPointe, G. (2004) Identification and characterization of a conserved nuclease secreted by strains of the Lactobacillus casei group. J. Appl. Microbiol. 96, 367-374 (Pubitemid 38223562)
33. Buchanan, J. T., Simpson, A. J., Aziz, R. K., Liu, G. Y., Kristian, S. A., Kotb, M., Feramisco, J., and Nizet, V. (2006) DNase expression allows the pathogen group A Streptococcus to escape killing in neutrophil extracellular traps. Curr. Biol. 16, 396-400 (Pubitemid 43259350)
34. Berends, E. T., Horswill, A. R., Haste, N. M., Monestier, M., Nizet, V., and Von Köckritz-Blickwede, M. (2010) Nuclease Expression by Staphylococcus aureus Facilitates Escape from Neutrophil Extracellular Traps. J. Innate Immun. 2, 576-586