메뉴 건너뛰기




Volumn 24, Issue 1, 2008, Pages 275-286

Exenatide effects on diabetes, obesity, cardiovascular risk factors and hepatic biomarkers in patients with type 2 diabetes treated for at least 3 years

Author keywords

ALT; AST; Exenatide; Exendin 4; HDLC; Incretin mimetic; LDL C; NAFLD; Triglycerides; Type 2 diabetes

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BIOLOGICAL MARKER; CHOLESTEROL; EXENDIN 4; LIPID; METFORMIN; PLACEBO; SULFONYLUREA; TRIACYLGLYCEROL;

EID: 38549162147     PISSN: 03007995     EISSN: None     Source Type: Journal    
DOI: 10.1185/030079907X253870     Document Type: Conference Paper
Times cited : (700)

References (34)
  • 1
    • 0141988862 scopus 로고    scopus 로고
    • Importance of weight management in type 2 diabetes: Review with meta-analysis of clinical studies
    • Anderson JW, Kendall CW, Jenkins DJ. Importance of weight management in type 2 diabetes: review with meta-analysis of clinical studies. J Am Coll Nutr 2003;22:331-9
    • (2003) J Am Coll Nutr , vol.22 , pp. 331-339
    • Anderson, J.W.1    Kendall, C.W.2    Jenkins, D.J.3
  • 4
    • 0033864648 scopus 로고    scopus 로고
    • Diabetes trends in the U.S.: 1990-1998
    • Mokdad AH, Ford ES, Bowman BA, et al. Diabetes trends in the U.S.: 1990-1998. Diabetes Care 2000;23:1278-83
    • (2000) Diabetes Care , vol.23 , pp. 1278-1283
    • Mokdad, A.H.1    Ford, E.S.2    Bowman, B.A.3
  • 5
    • 0037223174 scopus 로고    scopus 로고
    • Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001
    • Mokdad AH, Ford ES, Bowman BA, et al. Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001. JAMA 2003;289:76-9
    • (2003) JAMA , vol.289 , pp. 76-79
    • Mokdad, A.H.1    Ford, E.S.2    Bowman, B.A.3
  • 6
    • 2942657650 scopus 로고    scopus 로고
    • Medical consequences of obesity
    • Bray GA. Medical consequences of obesity. J Clin Endocrinol Metab 2004;89:2583-9
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 2583-2589
    • Bray, G.A.1
  • 8
    • 33846025092 scopus 로고    scopus 로고
    • Primary prevention of cardiovascular diseases in people with diabetes mellitus
    • Buse JB, Ginsberg HN, Bakris GL, et al. Primary prevention of cardiovascular diseases in people with diabetes mellitus. Diabetes Care 2007;30:162-72
    • (2007) Diabetes Care , vol.30 , pp. 162-172
    • Buse, J.B.1    Ginsberg, H.N.2    Bakris, G.L.3
  • 9
    • 0033807248 scopus 로고    scopus 로고
    • Intentional weight loss and mortality among overweight individuals with diabetes
    • Williamson DF, Thompson TJ, Thun M, et al. Intentional weight loss and mortality among overweight individuals with diabetes. Diabetes Care 2000;23:1499-1504
    • (2000) Diabetes Care , vol.23 , pp. 1499-1504
    • Williamson, D.F.1    Thompson, T.J.2    Thun, M.3
  • 10
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
    • UK Prospective Diabetes Study Group
    • UK Prospective Diabetes Study Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998;352:837-53
    • (1998) Lancet , vol.352 , pp. 837-853
  • 11
    • 0031964322 scopus 로고    scopus 로고
    • UK Prospective Diabetes Study 28. A randomized trial of efficacy of early addition of metformin in sulfonylurea-treated type 2 diabetes
    • UK Prospective Diabetes Study Group
    • UK Prospective Diabetes Study Group. UK Prospective Diabetes Study 28. A randomized trial of efficacy of early addition of metformin in sulfonylurea-treated type 2 diabetes. Diabetes Care 1998;21:87-92
    • (1998) Diabetes Care , vol.21 , pp. 87-92
  • 12
    • 1042280201 scopus 로고    scopus 로고
    • Glycemic control from 1988 to 2000 among U.S. adults diganosed with type 2 diabetes
    • Koro CM, Bowlin SJ, Bourgeois N, et al. Glycemic control from 1988 to 2000 among U.S. adults diganosed with type 2 diabetes. Diabetes Care 2004;27:17-20
    • (2004) Diabetes Care , vol.27 , pp. 17-20
    • Koro, C.M.1    Bowlin, S.J.2    Bourgeois, N.3
  • 14
    • 0029099086 scopus 로고
    • Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus
    • DeFronzo RA, Goodman AM. Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus. N Engl J Med 1995;333:541-9
    • (1995) N Engl J Med , vol.333 , pp. 541-549
    • DeFronzo, R.A.1    Goodman, A.M.2
  • 15
    • 0036829752 scopus 로고    scopus 로고
    • Medical position statement: Nonalcoholic fatty liver disease
    • American Gastroenterological Association
    • American Gastroenterological Association. Medical position statement: nonalcoholic fatty liver disease. Gastroenterology 2002;123:1702-4
    • (2002) Gastroenterology , vol.123 , pp. 1702-1704
  • 16
    • 0036829092 scopus 로고    scopus 로고
    • Technical review on nonalcoholic fatty liver disease
    • American Gastroenterological Association
    • American Gastroenterological Association. Technical review on nonalcoholic fatty liver disease. Gastroenterology 2002;123:1705-25
    • (2002) Gastroenterology , vol.123 , pp. 1705-1725
  • 17
    • 12744279669 scopus 로고    scopus 로고
    • Diabetes: Insulin resistance and derangements in lipid metabolism. Cure through intervention in fat transport and storage
    • Raz I, Eldor R, Cernea S, et al. Diabetes: insulin resistance and derangements in lipid metabolism. Cure through intervention in fat transport and storage. Diabetes Metab Res Rev 2005;21:3-14
    • (2005) Diabetes Metab Res Rev , vol.21 , pp. 3-14
    • Raz, I.1    Eldor, R.2    Cernea, S.3
  • 18
    • 33845273098 scopus 로고    scopus 로고
    • Exenatide effects on glucose metabolism and metabolic disorders common to overweight and obese patients with type 2 diabetes
    • Webb DM, Wintle M, Malone JK. Exenatide effects on glucose metabolism and metabolic disorders common to overweight and obese patients with type 2 diabetes. Drug Devel Res 2006;67:666-76
    • (2006) Drug Devel Res , vol.67 , pp. 666-676
    • Webb, D.M.1    Wintle, M.2    Malone, J.K.3
  • 19
    • 34247195226 scopus 로고    scopus 로고
    • A comparison of twice-daily exenatide and biphasic insulin aspart in patients with type 2 diabetes who were suboptimally controlled with sulfonylurea and metformin: A noninferiority study
    • Nauck MA, Duran S, Kim D, et al. A comparison of twice-daily exenatide and biphasic insulin aspart in patients with type 2 diabetes who were suboptimally controlled with sulfonylurea and metformin: a noninferiority study. Diabetologia 2007;50:259-67
    • (2007) Diabetologia , vol.50 , pp. 259-267
    • Nauck, M.A.1    Duran, S.2    Kim, D.3
  • 20
    • 34247259577 scopus 로고    scopus 로고
    • The effect of adding exenatide to a thiazolidinedione in suboptimally controlled type 2 diabetes
    • Zinman B, Hoogwerf BJ, Garcia SD, et al. The effect of adding exenatide to a thiazolidinedione in suboptimally controlled type 2 diabetes. Ann Intern Med 2007;146:477-85
    • (2007) Ann Intern Med , vol.146 , pp. 477-485
    • Zinman, B.1    Hoogwerf, B.J.2    Garcia, S.D.3
  • 21
    • 33845192364 scopus 로고    scopus 로고
    • Therapeutic applications of incretin mimetics for metabolic diseases: Preclinical studies
    • Mack CM, Laugero KD, Liu Q, et al. Therapeutic applications of incretin mimetics for metabolic diseases: preclinical studies. Drug Dev Res 2006;67:553-8
    • (2006) Drug Dev Res , vol.67 , pp. 553-558
    • Mack, C.M.1    Laugero, K.D.2    Liu, Q.3
  • 22
    • 7444228521 scopus 로고    scopus 로고
    • Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes
    • Buse JB, Henry RR, Han J, et al. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes. Diabetes Care 2004;27:2628-35
    • (2004) Diabetes Care , vol.27 , pp. 2628-2635
    • Buse, J.B.1    Henry, R.R.2    Han, J.3
  • 23
    • 18144401971 scopus 로고    scopus 로고
    • Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes
    • DeFronzo RA, Ratner RE, Han J, et al. Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes. Diabetes Care 2005;28:1092-1100
    • (2005) Diabetes Care , vol.28 , pp. 1092-1100
    • DeFronzo, R.A.1    Ratner, R.E.2    Han, J.3
  • 24
    • 17144371646 scopus 로고    scopus 로고
    • Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea
    • Kendall DM, Riddle MC, Rosenstock J, et al. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea. Diabetes Care 2005;28:1083-91
    • (2005) Diabetes Care , vol.28 , pp. 1083-1091
    • Kendall, D.M.1    Riddle, M.C.2    Rosenstock, J.3
  • 25
    • 33947156808 scopus 로고    scopus 로고
    • Metabolic effects of two years of exenatide treatment on diabetes, obesity, and hepatic biomarkers in patients widi type 2 diabetes: An interim analysis of data from the open-label, uncontrolled extension of three double-blind, placebo-controlled trials
    • Buse JB, Klonoff DC, Nielsen LL, et al. Metabolic effects of two years of exenatide treatment on diabetes, obesity, and hepatic biomarkers in patients widi type 2 diabetes: an interim analysis of data from the open-label, uncontrolled extension of three double-blind, placebo-controlled trials. Clin Ther 2007;29:139-53
    • (2007) Clin Ther , vol.29 , pp. 139-153
    • Buse, J.B.1    Klonoff, D.C.2    Nielsen, L.L.3
  • 26
    • 33748442464 scopus 로고    scopus 로고
    • Interim analysis of the effects of exenatide treatment on A1C, weight and cardiovascular risk factors over 82 weeks in 314 overweight patients with type 2 diabetes
    • Blonde L, Klein EJ, Han J, et al. Interim analysis of the effects of exenatide treatment on A1C, weight and cardiovascular risk factors over 82 weeks in 314 overweight patients with type 2 diabetes. Diabetes Obes Metab 2006;8:436-47
    • (2006) Diabetes Obes Metab , vol.8 , pp. 436-447
    • Blonde, L.1    Klein, E.J.2    Han, J.3
  • 27
    • 0031578033 scopus 로고    scopus 로고
    • Declaration of Helsinski: Recommendations guiding medical physicians in biomedical research involving human subjects
    • Declaration of Helsinski: Recommendations guiding medical physicians in biomedical research involving human subjects. JAMA 1997;277:925-6
    • (1997) JAMA , vol.277 , pp. 925-926
  • 28
    • 0037008087 scopus 로고    scopus 로고
    • Updated definitions of healthy ranges for serum alanine aminotransferase levels
    • Prati D, Taioli E, Zanella A, et al. Updated definitions of healthy ranges for serum alanine aminotransferase levels. Ann Intern Med 2002;137:1-10
    • (2002) Ann Intern Med , vol.137 , pp. 1-10
    • Prati, D.1    Taioli, E.2    Zanella, A.3
  • 29
    • 0034819464 scopus 로고    scopus 로고
    • Combination therapies with insulin in type 2 diabetes
    • Yki-Järvinen H. Combination therapies with insulin in type 2 diabetes. Diabetes Care 2001;24:758-67
    • (2001) Diabetes Care , vol.24 , pp. 758-767
    • Yki-Järvinen, H.1
  • 30
    • 0042861368 scopus 로고    scopus 로고
    • Weight effect of current and experimental drugs for diabetes mellitus: From promotion to alleviation of obesity
    • Purnell JQ, Weyer C. Weight effect of current and experimental drugs for diabetes mellitus: from promotion to alleviation of obesity. Treat Endocrinol 2003;2:33-47
    • (2003) Treat Endocrinol , vol.2 , pp. 33-47
    • Purnell, J.Q.1    Weyer, C.2
  • 31
    • 0344609217 scopus 로고    scopus 로고
    • Causes of weight gain during insulin therapy with and without metformin in patients with Type II diabetes mellitus
    • Makimattila S, Nikkila K, Yki-Jarvinen H. Causes of weight gain during insulin therapy with and without metformin in patients with Type II diabetes mellitus. Diabetologia 1999;42:406-12
    • (1999) Diabetologia , vol.42 , pp. 406-412
    • Makimattila, S.1    Nikkila, K.2    Yki-Jarvinen, H.3
  • 32
    • 0038017098 scopus 로고    scopus 로고
    • Current best treatment for non-alcoholic fatty liver disease
    • Angulo P. Current best treatment for non-alcoholic fatty liver disease. Exp Opinion Pharmacother 2003;4:611-23
    • (2003) Exp Opinion Pharmacother , vol.4 , pp. 611-623
    • Angulo, P.1
  • 33
    • 33644803761 scopus 로고    scopus 로고
    • Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob mice
    • Ding X, Saxena NK, Lin S, et al. Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob mice. Hepatology 2006;43:173-81
    • (2006) Hepatology , vol.43 , pp. 173-181
    • Ding, X.1    Saxena, N.K.2    Lin, S.3
  • 34
    • 33748303040 scopus 로고    scopus 로고
    • Incretin mimetics as a novel therapeutic option for hepatic steatosis
    • Tushuizen ME, Bunck MC, Pouwels PJ, et al. Incretin mimetics as a novel therapeutic option for hepatic steatosis. Liver Int 2006;26:1015-17
    • (2006) Liver Int , vol.26 , pp. 1015-1017
    • Tushuizen, M.E.1    Bunck, M.C.2    Pouwels, P.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.