Curcumin inhibits cell growth and induces cell apoptosis through upregulation of miR-33b in gastric cancer

Tumor Biology

Volumn 37, Issue 10, 2016, Pages 13177-13184

  Sun, Qianqian ^a   Zhang, Wenjing ^b   Guo, Yanjie ^a   Li, Zhuyao ^a   Chen, Xiaonan ^a   Wang, Yuanyuan ^a   Du, Yuwen ^a   Zang, Wenqiao ^a   Zhao, Guoqiang ^a,c  

^a ZHENGZHOU UNIVERSITY   (China)

^b HENAN UNIVERSITY OF CHINESE MEDICINE   (China)

^c Provincial Cooperative Innovation Center for Cancer Chemoprevention   (China)

Author keywords

Apoptosis; Curcumin; Gastric cancer; miR 33b; Proliferation; XIAP

Indexed keywords

CURCUMIN; MICRORNA; MICRORNA 33B; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS; 3' UNTRANSLATED REGION; ANTINEOPLASTIC AGENT; MESSENGER RNA; MIRN33 MICRORNA, HUMAN; XIAP PROTEIN, HUMAN;

APOPTOSIS; APOPTOSIS ASSAY; ARTICLE; BIOINFORMATICS; CANCER GROWTH; CANCER INHIBITION; CELL COUNTING; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; GASTRIC CANCER CELL LINE; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; LUCIFERASE ASSAY; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; STOMACH CANCER; UPREGULATION; WESTERN BLOTTING; XIAP GENE; 3' UNTRANSLATED REGION; BINDING SITE; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; NUCLEOTIDE SEQUENCE; PATHOLOGY; RNA INTERFERENCE; STOMACH TUMOR; TUMOR CELL LINE;

3' UNTRANSLATED REGIONS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BASE SEQUENCE; BINDING SITES; CELL LINE, TUMOR; CELL PROLIFERATION; CURCUMIN; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICRORNAS; RNA INTERFERENCE; RNA, MESSENGER; STOMACH NEOPLASMS; UP-REGULATION; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 84979574767     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-016-5221-9     Document Type: Article

References (29)

1. Piazuelo MB, Correa P. Gastric cáncer: overview. Colomb Med (Cali). 2013;44:192–201.
2. Takashima A, Shirao K, Hirashima Y, Takahari D, Okita NT, Nakajima TE, et al. Sequential chemotherapy with methotrexate and 5-fluorouracil for chemotherapy-naive advanced gastric cancer with disseminated intravascular coagulation at initial diagnosis. J Cancer Res Clin Oncol. 2010;136:243–8.
3. Ambros V. The functions of animal microRNAs. Nature. 2004;431:350–5.
4. Hobert O. Gene regulation by transcription factors and transnational silencing. Cell. 2007;131:25–8.
5. Farazi TA, Spitzer JI, Morozov P, Tuschl T. miRNAs in human cancer. J Pathol. 2011;223:102–15.
6. Zhang Q, Sun H, Jiang Y, Ding L, Wu S, Fang T, et al. MicroRNA-181a suppresses mouse granulosa cell proliferation by targeting activin receptor IIA. PLoS One. 2013;8:e59667.
7. Wu C, Zheng X, Li X, Fesler A, Hu W, Chen L, et al. Reduction of gastric cancer proliferation and invasion by miR-15a mediated suppression of Bmi-1 translation. Oncotarget. 2016;7:14522–36.
8. Li Y, Chen D, Jin LU, Liu J, Li Y, Su Z, et al. Oncogenic microRNA-142-3p is associated with cellular migration, proliferation and apoptosis in renal cell carcinoma. Oncol Lett. 2016;11:1235–41.
9. Shang Y, Feng B, Zhou L, Ren G, Zhang Z, Fan X, et al. The miR27b-CCNG1-P53-miR-508-5p axis regulates multidrug resistance of gastric cancer. Oncotarget. 2016;7:538–49.
10. Eto K, Iwatsuki M, Watanabe M, Ida S, Ishimoto T, Iwagami S, et al. The microRNA-21/PTEN pathway regulates the sensitivity of HER2-positive gastric cancer cells to trastuzumab. Ann Surg Oncol. 2014;21:343–50.
11. Zhang F, Yang R, Zhang G, Cheng R, Bai Y, Zhao H, et al. Anticancer function of α-solanine in lung adenocarcinoma cells by inducing microRNA-138 expression. Tumour Biol. 2015 Dec 2.
12. Kunnumakkara AB, Anand P, Aggarwal BB. Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins. Cancer Lett. 2008;269:199–225.
13. Guan F, Ding Y, Zhang Y, Zhou Y, Li M, Wang C. Curcumin suppresses proliferation and migration of MDA-MB-231 breast cancer cells through autophagy-dependent Akt degradation. PLoS One. 2016;11:e0146553.
14. Huang H, Chen X, Li D, He Y, Li Y, Du Z, et al. Combination of α-Tomatine and curcumin inhibits growth and induces apoptosis in human prostate cancer cells. PLoS One. 2015;10:e0144293.
15. Tsai JR, Liu PL, Chen YH, Chou SH, Cheng YJ, Hwang JJ, et al. Curcumin inhibits non-small cell lung cancer cells metastasis through the Adiponectin/NF-κb/MMPs signaling pathway. PLoS One. 2015;10:e0144462.
16. Lin ML, YC L, Chen HY, Lee CC, Chung JG, Chen SS. Suppressing the formation of lipid raft-associated Rac1/PI3K/Akt signaling complexes by curcumin inhibits SDF-1α-induced invasion of human esophageal carcinoma cells. Mol Carcinog. 2014;53:360–79.
17. Liu X, Sun K, Song A, Zhang X, Zhang X, He X. Curcumin inhibits proliferation of gastric cancer cells by impairing ATP-sensitive potassium channel opening. World J Surg Oncol. 2014;12:389.
18. Ding XQ, TT G, Wang W. Curcumin protects against fructose-induced podocyte insulin signaling impairment through upregulation of miR-206. Mol Nutr Food Res. 2015;59:2355–70.
19. Guo H, Xu Y, Q F. Curcumin inhibits growth of prostate carcinoma via miR-208-mediated CDKN1A activation. Tumour Biol. 2015;36:8511–7.
20. Zhang P, Bai H, Liu G, Wang H, Chen F, Zhang B, et al. MicroRNA-33b, upregulated by EF24, a curcumin analog, suppresses the epithelial-to-mesenchymal transition (EMT) and migratory potential of melanoma cells by targeting HMGA2. Toxicol Lett. 2015;234:151–61.
21. Zhou X, Wang W, Li P, Zheng Z, Tu Y, Zhang Y, et al. Curcumin enhances the effects of 5-fluorouracil and Oxaliplatin in inducing gastric cancer cell apoptosis both in vitro and in vivo. Oncol Res. 2016;23:29–34.
22. Uehara Y, Inoue M, Fukuda K, Yamakoshi H, Hosoi Y, Kanda H, et al. Inhibition of β-catenin and STAT3 with a curcumin analog suppresses gastric carcinogenesis in vivo. Gastric Cancer. 2015;18:774–83.
23. Lin Y, Liu AY, Fan C, Zheng H, Li Y, Zhang C, et al. MicroRNA-33b inhibits breast cancer metastasis by targeting HMGA2, SALL4 and Twist1. Sci Rep. 2015;5:9995.
24. Qu J, Li M, An J, Zhao B, Zhong W, Gu Q, et al. MicroRNA-33b inhibits lung adenocarcinoma cell growth, invasion, and epithelial-mesenchymal transition by suppressing Wnt/β-catenin/ZEB1 signaling. Int J Oncol 2015;47:2141–2152.
25. Xu N, Li Z, Yu Z, Yan F, Liu Y, Lu X, et al. MicroRNA-33b suppresses migration and invasion by targeting c-Myc in osteosarcoma cells. PLoS One. 2014;9:e115300.
26. Yin H, Song P, Su R, Yang G, Dong L, Luo M, et al. DNA methylation mediated down-regulating of MicroRNA-33b and its role in gastric cancer. Sci Rep. 2016;6:18824.
27. Hock M, Gibson H, Korneluk RG. XIAP: apoptotic brake and promising therapeutic target. Apoptosis. 2001;6:253–61.
28. Werner TA, Tamkan-Ölcek Y, Dizdar L, Riemer JC, Wolf A, Cupisti K, et al. Survivin and XIAP: two valuable biomarkers in medullary thyroid carcinoma. Br J Cancer. 2016;114:427–34.
29. Tong QS, Zheng LD, Wang L, Zeng FQ, Chen FM, Dong JH, et al. Downregulation of XIAP expression induces apoptosis and enhances chemotherapeutic sensitivity in human gastric cancer cells. Cancer Gene Ther. 2005;12:509–14.