메뉴 건너뛰기




Volumn 47, Issue 6, 2015, Pages 2141-2152

MicroRNA-33b inhibits lung adenocarcinoma cell growth, invasion, and epithelial-mesenchymal transition by suppressing Wnt/β-catenin/ZEB1 signaling

Author keywords

Epithelial mesenchymal transition; Invasion and migration; Lung adenocarcinoma; MicroRNA; MIR 33b

Indexed keywords

BETA CATENIN; MESSENGER RNA; MICRORNA; MICRORNA 33B; TRANSCRIPTION FACTOR ZEB1; UNCLASSIFIED DRUG; WNT PROTEIN; HOMEODOMAIN PROTEIN; MIRN33 MICRORNA, HUMAN; TRANSCRIPTION FACTOR; ZEB1 PROTEIN, HUMAN;

EID: 84982719133     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2015.3187     Document Type: Article
Times cited : (73)

References (54)
  • 2
    • 33947502512 scopus 로고    scopus 로고
    • Lung cancer in never smokers: A review
    • Subramanian J and Govindan R: Lung cancer in never smokers: A review. J Clin Oncol 25:561-570, 2007.
    • (2007) J Clin Oncol , vol.25 , pp. 561-570
    • Subramanian, J.1    Govindan, R.2
  • 3
    • 45349086437 scopus 로고    scopus 로고
    • Comparison of aspects of smoking among the four histological types of lung cancer
    • Kenfield SA, Wei EK, Stampfer MJ, Rosner BA and Colditz GA: Comparison of aspects of smoking among the four histological types of lung cancer. Tob Control 17:198-204, 2008.
    • (2008) Tob Control , vol.17 , pp. 198-204
    • Kenfield, S.A.1    Wei, E.K.2    Stampfer, M.J.3    Rosner, B.A.4    Colditz, G.A.5
  • 4
    • 33751252276 scopus 로고    scopus 로고
    • Cancer metastasis: Building a framework
    • Gupta GP and Massagué J: Cancer metastasis: Building a framework. Cell 127:679-695, 2006.
    • (2006) Cell , vol.127 , pp. 679-695
    • Gupta, G.P.1    Massagué, J.2
  • 5
    • 84883049288 scopus 로고    scopus 로고
    • Lung cancer screening: Past, present and future
    • Finigan JH and Kern JA: Lung cancer screening: Past, present and future. Clin Chest Med 34:365-371, 2013.
    • (2013) Clin Chest Med , vol.34 , pp. 365-371
    • Finigan, J.H.1    Kern, J.A.2
  • 7
  • 8
    • 67650996280 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions: The importance of changing cell state in development and disease
    • Acloque H, Adams MS, Fishwick K, Bronner-Fraser M and Nieto MA: Epithelial-mesenchymal transitions: The importance of changing cell state in development and disease. J Clin Invest 119:1438-1449, 2009.
    • (2009) J Clin Invest , vol.119 , pp. 1438-1449
    • Acloque, H.1    Adams, M.S.2    Fishwick, K.3    Bronner-Fraser, M.4    Nieto, M.A.5
  • 9
    • 79251547708 scopus 로고    scopus 로고
    • Up-regulation of sonic hedgehog contributes to TGF-β1-induced epithelial to mesenchymal transition in NSCLC cells
    • Maitah MY, Ali S, Ahmad A, Gadgeel S and Sarkar FH: Up-regulation of sonic hedgehog contributes to TGF-β1-induced epithelial to mesenchymal transition in NSCLC cells. PLoS One 6:e16068, 2011.
    • (2011) PLoS One , vol.6 , pp. e16068
    • Maitah, M.Y.1    Ali, S.2    Ahmad, A.3    Gadgeel, S.4    Sarkar, F.H.5
  • 10
    • 44449111555 scopus 로고    scopus 로고
    • Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways
    • Onder TT, Gupta PB, Mani SA, Yang J, Lander ES and Weinberg RA: Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. Cancer Res 68:3645-3654, 2008.
    • (2008) Cancer Res , vol.68 , pp. 3645-3654
    • Onder, T.T.1    Gupta, P.B.2    Mani, S.A.3    Yang, J.4    Lander, E.S.5    Weinberg, R.A.6
  • 12
    • 84876254445 scopus 로고    scopus 로고
    • Inhibition of ZEB1 reverses EMT and chemoresistance in docetaxel-resistant human lung adenocarcinoma cell line
    • Ren J, Chen Y, Song H, Chen L and Wang R: Inhibition of ZEB1 reverses EMT and chemoresistance in docetaxel-resistant human lung adenocarcinoma cell line. J Cell Biochem 114:1395-1403, 2013.
    • (2013) J Cell Biochem , vol.114 , pp. 1395-1403
    • Ren, J.1    Chen, Y.2    Song, H.3    Chen, L.4    Wang, R.5
  • 13
    • 84864319635 scopus 로고    scopus 로고
    • Zinc finger E-box binding homeobox 1 promotes invasion and bone metastasis of small cell lung cancer in vitro and in vivo
    • Liu Y, Zhang N, Wang Y, Xu M, Liu N, Pang X, Cao J, Ma N, Pang H, Liu L, et al: Zinc finger E-box binding homeobox 1 promotes invasion and bone metastasis of small cell lung cancer in vitro and in vivo. Cancer Sci 103:1420-1428, 2012.
    • (2012) Cancer Sci , vol.103 , pp. 1420-1428
    • Liu, Y.1    Zhang, N.2    Wang, Y.3    Xu, M.4    Liu, N.5    Pang, X.6    Cao, J.7    Ma, N.8    Pang, H.9    Liu, L.10
  • 14
    • 84936846402 scopus 로고    scopus 로고
    • Interplay between microRNAs and WNT/β-catenin signalling pathway regulates epithelialmesenchymal transition in cancer
    • Ghahhari NM and Babashah S: Interplay between microRNAs and WNT/β-catenin signalling pathway regulates epithelialmesenchymal transition in cancer. Eur J Cancer 51:1638-1649, 2015.
    • (2015) Eur J Cancer , vol.51 , pp. 1638-1649
    • Ghahhari, N.M.1    Babashah, S.2
  • 15
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in development and disease
    • Clevers H: Wnt/beta-catenin signaling in development and disease. Cell 127:469-480, 2006.
    • (2006) Cell , vol.127 , pp. 469-480
    • Clevers, H.1
  • 18
    • 38749108492 scopus 로고    scopus 로고
    • Wnt1 overexpression associated with tumor proliferation and a poor prognosis in non-small cell lung cancer patients
    • Nakashima T, Liu D, Nakano J, Ishikawa S, Yokomise H, Ueno M, Kadota K and Huang CL: Wnt1 overexpression associated with tumor proliferation and a poor prognosis in non-small cell lung cancer patients. Oncol Rep 19:203-209, 2008.
    • (2008) Oncol Rep , vol.19 , pp. 203-209
    • Nakashima, T.1    Liu, D.2    Nakano, J.3    Ishikawa, S.4    Yokomise, H.5    Ueno, M.6    Kadota, K.7    Huang, C.L.8
  • 20
    • 79958288052 scopus 로고    scopus 로고
    • MicroRNA-451 functions as a tumor suppressor in human non-small cell lung cancer by targeting ras-related protein 14 (RAB14)
    • Wang R, Wang ZX, Yang JS, Pan X, De W and Chen LB: MicroRNA-451 functions as a tumor suppressor in human non-small cell lung cancer by targeting ras-related protein 14 (RAB14). Oncogene 30:2644-2658, 2011.
    • (2011) Oncogene , vol.30 , pp. 2644-2658
    • Wang, R.1    Wang, Z.X.2    Yang, J.S.3    Pan, X.4    De, W.5    Chen, L.B.6
  • 23
    • 1942435249 scopus 로고    scopus 로고
    • Micromanagers of gene expression: The potentially widespread influence of metazoan microRNAs
    • Bartel DP and Chen CZ: Micromanagers of gene expression: The potentially widespread influence of metazoan microRNAs. Nat Rev Genet 5:396-400, 2004.
    • (2004) Nat Rev Genet , vol.5 , pp. 396-400
    • Bartel, D.P.1    Chen, C.Z.2
  • 24
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP: MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell 116:281-297, 2004.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 25
    • 33748928159 scopus 로고    scopus 로고
    • The diverse functions of microRNAs in animal development and disease
    • Kloosterman WP and Plasterk RH: The diverse functions of microRNAs in animal development and disease. Dev Cell 11:441-450, 2006.
    • (2006) Dev Cell , vol.11 , pp. 441-450
    • Kloosterman, W.P.1    Plasterk, R.H.2
  • 27
    • 33645321647 scopus 로고    scopus 로고
    • MicroRNAs in cell proliferation, cell death, and tumorigenesis
    • Hwang HW and Mendell JT: MicroRNAs in cell proliferation, cell death, and tumorigenesis. Br J Cancer 94:776-780, 2006.
    • (2006) Br J Cancer , vol.94 , pp. 776-780
    • Hwang, H.W.1    Mendell, J.T.2
  • 28
    • 84867334466 scopus 로고    scopus 로고
    • Silencing of miRNA-218 promotes migration and invasion of breast cancer via Slit2-Robo1 pathway
    • Yang L, Li Q, Wang Q, Jiang Z and Zhang L: Silencing of miRNA-218 promotes migration and invasion of breast cancer via Slit2-Robo1 pathway. Biomed Pharmacother 66:535-540, 2012.
    • (2012) Biomed Pharmacother , vol.66 , pp. 535-540
    • Yang, L.1    Li, Q.2    Wang, Q.3    Jiang, Z.4    Zhang, L.5
  • 29
    • 84907219376 scopus 로고    scopus 로고
    • Transforming growth factor-β-induced MIR-143 expression in regulation of non-small cell lung cancer cell viability and invasion capacity in vitro and in vivo
    • Cheng T, Hu C, Yang H, Cao L and An J: Transforming growth factor-β-induced miR-143 expression in regulation of non-small cell lung cancer cell viability and invasion capacity in vitro and in vivo. Int J Oncol 45:1977-1988, 2014.
    • (2014) Int J Oncol , vol.45 , pp. 1977-1988
    • Cheng, T.1    Hu, C.2    Yang, H.3    Cao, L.4    An, J.5
  • 31
    • 84874669506 scopus 로고    scopus 로고
    • Downregulated microRNA-200a promotes EMT and tumor growth through the wnt/β-catenin pathway by targeting the E-cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma
    • Cong N, Du P, Zhang A, Shen F, Su J, Pu P, Wang T, Zjang J, Kang C and Zhang Q: Downregulated microRNA-200a promotes EMT and tumor growth through the wnt/β-catenin pathway by targeting the E-cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma. Oncol Rep 29:1579-1587, 2013.
    • (2013) Oncol Rep , vol.29 , pp. 1579-1587
    • Cong, N.1    Du, P.2    Zhang, A.3    Shen, F.4    Su, J.5    Pu, P.6    Wang, T.7    Zjang, J.8    Kang, C.9    Zhang, Q.10
  • 33
    • 84862776527 scopus 로고    scopus 로고
    • A systematicanalysis of predicted MIR-21 targets identifies a signature for lung cancer
    • Gao W, Xu J, Liu L, Shen H, Zeng H and Shu Y: A systematicanalysis of predicted miR-21 targets identifies a signature for lung cancer. Biomed Pharmacother 66:21-28, 2012.
    • (2012) Biomed Pharmacother , vol.66 , pp. 21-28
    • Gao, W.1    Xu, J.2    Liu, L.3    Shen, H.4    Zeng, H.5    Shu, Y.6
  • 36
    • 84872841726 scopus 로고    scopus 로고
    • Curcumin inhibits LPS-induced EMT through downregulation of NF-κB-Snail signaling in breast cancer cells
    • Huang T, Chen Z and Fang L: Curcumin inhibits LPS-induced EMT through downregulation of NF-κB-Snail signaling in breast cancer cells. Oncol Rep 29:117-124, 2013.
    • (2013) Oncol Rep , vol.29 , pp. 117-124
    • Huang, T.1    Chen, Z.2    Fang, L.3
  • 37
    • 34548500802 scopus 로고    scopus 로고
    • Delta5 desaturase mRNA levels are increased by simvastatin via SREBP-1 at early stages, not via PPARalpha, in THP-1 cells
    • Rise P, Ghezzi S, Carissimi R, Mastromauro F, Petroni A and Galli C: Delta5 desaturase mRNA levels are increased by simvastatin via SREBP-1 at early stages, not via PPARalpha, in THP-1 cells. Eur J Pharmacol 571:97-105, 2007.
    • (2007) Eur J Pharmacol , vol.571 , pp. 97-105
    • Rise, P.1    Ghezzi, S.2    Carissimi, R.3    Mastromauro, F.4    Petroni, A.5    Galli, C.6
  • 41
    • 0030877137 scopus 로고    scopus 로고
    • Aldesleukin (recombinant interleukin-2)
    • Noble S and Goa KL: Aldesleukin (recombinant interleukin-2). BioDrugs 7:394-422, 1997.
    • (1997) BioDrugs , vol.7 , pp. 394-422
    • Noble, S.1    Goa, K.L.2
  • 43
    • 67650165335 scopus 로고    scopus 로고
    • Interleukin-2: Evaluation of routes of administration and current delivery systems in cancer therapy
    • Shaker MA and Younes HM: Interleukin-2: Evaluation of routes of administration and current delivery systems in cancer therapy. J Pharm Sci 98:2268-2298, 2009.
    • (2009) J Pharm Sci , vol.98 , pp. 2268-2298
    • Shaker, M.A.1    Younes, H.M.2
  • 44
    • 84897410473 scopus 로고    scopus 로고
    • Inhibition of TBK1 attenuates radiation-induced epithelial-mesenchymal transition of A549 human lung cancer cells via activation of GSK-3β and repression of ZEB1
    • Liu W, Huang YJ, Liu C, Yang YY, Liu H, Cui JG, Cheng Y, Gao F, Cai JM and Li BL: Inhibition of TBK1 attenuates radiation-induced epithelial-mesenchymal transition of A549 human lung cancer cells via activation of GSK-3β and repression of ZEB1. Lab Invest 94:362-370, 2014.
    • (2014) Lab Invest , vol.94 , pp. 362-370
    • Liu, W.1    Huang, Y.J.2    Liu, C.3    Yang, Y.Y.4    Liu, H.5    Cui, J.G.6    Cheng, Y.7    Gao, F.8    Cai, J.M.9    Li, B.L.10
  • 46
    • 33744925683 scopus 로고    scopus 로고
    • Cyclooxygenase-2-dependent regulation of E-cadherin: Prostaglandin E (2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer
    • Dohadwala M, Yang SC, Luo J, Sharma S, Batra RK, Huang M, Lin Y, Goodglick L, Krysan K, Fishbein MC, et al: Cyclooxygenase-2-dependent regulation of E-cadherin: Prostaglandin E (2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer. Cancer Res 66:5338-5345, 2006.
    • (2006) Cancer Res , vol.66 , pp. 5338-5345
    • Dohadwala, M.1    Yang, S.C.2    Luo, J.3    Sharma, S.4    Batra, R.K.5    Huang, M.6    Lin, Y.7    Goodglick, L.8    Krysan, K.9    Fishbein, M.C.10
  • 48
    • 84892934487 scopus 로고    scopus 로고
    • CUL4A induces epithelial-mesenchymal transition and promotes cancer metastasis by regulating ZEB1 expression
    • Wang Y, Wen M, Kwon Y, Xu Y, Liu Y, Zhang P, He X, Wang Q, Huang Y, Jen KY, et al: CUL4A induces epithelial-mesenchymal transition and promotes cancer metastasis by regulating ZEB1 expression. Cancer Res 74:520-531, 2014.
    • (2014) Cancer Res , vol.74 , pp. 520-531
    • Wang, Y.1    Wen, M.2    Kwon, Y.3    Xu, Y.4    Liu, Y.5    Zhang, P.6    He, X.7    Wang, Q.8    Huang, Y.9    Jen, K.Y.10
  • 50
    • 80155126639 scopus 로고    scopus 로고
    • A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors
    • Ohashi S, Natsuizaka M, Naganuma S, Kagawa S, Kimura S, Itoh H, Kalman RA, Nakagawa M, Darling DS, Basu D, et al: A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors. Cancer Res 71:6836-6847, 2011.
    • (2011) Cancer Res , vol.71 , pp. 6836-6847
    • Ohashi, S.1    Natsuizaka, M.2    Naganuma, S.3    Kagawa, S.4    Kimura, S.5    Itoh, H.6    Kalman, R.A.7    Nakagawa, M.8    Darling, D.S.9    Basu, D.10
  • 52
    • 79953026583 scopus 로고    scopus 로고
    • Aberrant Wnt1/β-catenin expression is an independent poor prognostic marker of non-small cell lung cancer after surgery
    • Xu X, Sun PL, Li JZ, Jheon S, Lee CT and Chung JH: Aberrant Wnt1/β-catenin expression is an independent poor prognostic marker of non-small cell lung cancer after surgery. J Thorac Oncol 6:716-724, 2011.
    • (2011) J Thorac Oncol , vol.6 , pp. 716-724
    • Xu, X.1    Sun, P.L.2    Li, J.Z.3    Jheon, S.4    Lee, C.T.5    Chung, J.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.