Microfluidic microscopy-assisted label-free approach for cancer screening: automated microfluidic cytology for cancer screening

Medical and Biological Engineering and Computing

Volumn 55, Issue 5, 2017, Pages 711-718

  Jagannadh, Veerendra Kalyan ^a   Gopakumar, G ^b   Subrahmanyam, Gorthi R K Sai ^b   Gorthi, Sai Siva ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

^b INDIAN INSTITUTE OF SPACE SCIENCE AND TECHNOLOGY   (India)

Author keywords

Cancer diagnostics; Cell identification; High throughput imaging; Optofluidic imaging

Indexed keywords

CELLS; COMPUTER VISION; COST EFFECTIVENESS; CYTOLOGY; DEVELOPING COUNTRIES; DIAGNOSIS; FACE RECOGNITION; MICROFLUIDICS; POPULATION STATISTICS; PRINCIPAL COMPONENT ANALYSIS; SECURITY SYSTEMS;

2D PRINCIPAL COMPONENT ANALYSIS; CANCER DIAGNOSTICS; CELL IDENTIFICATION; COMPUTER VISION TECHNIQUES; FACE RECOGNITION SYSTEMS; HIGH-THROUGHPUT IMAGING; OPTOFLUIDIC; SIGNATURE-BASED APPROACH;

DISEASES;

ARTICLE; CANCER MORTALITY; CANCER SCREENING; CLASSIFICATION; CYTOLOGY; DEVELOPING COUNTRY; FACIAL RECOGNITION; MASS SCREENING; MICROFLUIDIC ANALYSIS; MICROSCOPY; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; SUPPORT VECTOR MACHINE;

EID: 84979539053     PISSN: 01400118     EISSN: 17410444     Source Type: Journal    
DOI: 10.1007/s11517-016-1549-y     Document Type: Article

References (30)

1. Bancroft JD (2008) Theory and practice of histological techniques. Elsevier Health Sciences, Amsterdam
2. Basiji DA, Ortyn WE, Liang L, Venkatachalam V, Morrissey P (2007) Cellular image analysis and imaging by flow cytometry. Clin Lab Med 27(3):653–670. doi:10.1016/j.cll.2007.05.008
3. Caprio GD, Stokes C, Higgins JM, Schonbrun E (2015) Single-cell measurement of red blood cell oxygen affinity. Proc Natl Acad Sci USA 112(32):9984–9989. doi:10.1073/pnas.1509252112
4. Cohen SJ, Punt CJA, Iannotti N, Saidman BH, Sabbath KD, Gabrail NY, Picus J, Morse M, Mitchell E, Miller MC, Doyle GV, Tissing H, Terstappen LWMM, Meropol NJ (2008) Relationship of circulating tumor cells to tumor response, progression-free survival, and overall survival in patients with metastatic colorectal cancer. J Clin Oncol 26(19):3213–3221. doi:10.1200/JCO.2007.15.8923
5. Dey P (2010) Cancer nucleus: morphology and beyond. Diagn Cytopathol 38(5):382–390. doi:10.1002/dc.21234
6. Goda K, Ayazi A, Gossett DR, Sadasivam J, Lonappan CK, Sollier E, Fard AM, Hur SC, Adam J, Murray C, Wang C, Brackbill N, Carlo DD, Jalali B (2012) High-throughput single-microparticle imaging flow analyzer. Proc Natl Acad Sci USA 109(29):11630–11635. doi:10.1073/pnas.1204718109
7. Gopakumar G, Subrahmanyam GRKS, Siva GS (2014) Morphology based classification of leukemia cell lines: K562 and MOLT in a microfluidics based imaging flow cytometer. In: Proceedings of the 2014 Indian conference on computer vision, graphics and image processing, ICVGIP’14, Bangalore, India, December 14–18, 2014, pp 34:1–34:7. doi:10.1145/2683483.2683517
8. Gopakumar G, Jagannadh VK, Gorthi SS, Subrahmanyam GRKS (2016) Framework for morphometric classification of cells in imaging flow cytometry. J Microsc 261(3):307–319. doi:10.1111/jmi.12335
9. Gorthi SS, Schonbrun E (2012) Phase imaging flow cytometry using a focus-stack collecting microscope. Opt Lett 37(4):707–709. doi:10.1364/OL.37.000707
10. Gorthi SS, Schaak D, Schonbrun E (2013) Fluorescence imaging of flowing cells using a temporally coded excitation. Opt Express 21(4):5164–5170. doi:10.1364/OE.21.005164
11. Kachel V, Benker G, Lichtnau K, Valet G, Glossner E (1979) Fast imaging in flow: a means of combining flow-cytometry and image analysis. J Histochem Cytochem 27(1):335–341. doi:10.1177/27.1.374598
12. Kay DB, Cambier JL, Wheeless LL (1979) Imaging in flow. J Histochem Cytochem 27(1):329–334. doi:10.1177/27.1.374597
13. Kirby M, Sirovich L (1990) Application of the Karhunen–Loeve procedure for the characterization of human faces. IEEE Trans Pattern Anal Mach Intell 12(1):103–108. doi:10.1109/34.41390
14. Nayar R (2014) Cytopathology in oncology. Springer, Berlin
15. Ng EX, Miller MA, Jing T, Lauffenburger DA, Chen CH (2015) Low-volume multiplexed proteolytic activity assay and inhibitor analysis through a pico-injector array. Lab Chip 15(4):1153–1159. doi:10.1039/C4LC01162G
16. Ng EX, Miller MA, Jing T, Chen CH (2016) Single cell multiplexed assay for proteolytic activity using droplet microfluidics. Biosens Bioelectron 81:408–414. doi:10.1016/j.bios.2016.03.002
17. Otto O, Rosendahl P, Mietke A, Golfier S, Herold C, Klaue D, Girardo S, Pagliara S, Ekpenyong A, Jacobi A, Wobus M, Tpfner N, Keyser UF, Mansfeld J, Fischer-Friedrich E, Guck J (2015) Real-time deformability cytometry: on-the-fly cell mechanical phenotyping. Nat Methods 12(3):199–202. doi:10.1038/nmeth.3281, 4 p following 202
18. Schonbrun E, Gorthi SS, Schaak D (2012) Microfabricated multiple field of view imaging flow cytometry. Lab Chip 12(2):268–273. doi:10.1039/c1lc20843h
19. Schonbrun E, Di Caprio G, Schaak D (2013) Dye exclusion microfluidic microscopy. Opt Express 21(7):8793–8798. doi:10.1364/OE.21.008793
20. Schonbrun E, Malka R, Di Caprio G, Schaak D, Higgins JM (2014) Quantitative absorption cytometry for measuring red blood cell hemoglobin mass and volume. Cytometry A 85(4):332–338. doi:10.1002/cyto.a.22450
21. Solomon D (2003) Chapter 14: role of triage testing in cervical cancer screening. JNCI Monogr 2003(31):97–101
22. Stewart BW (2014) Wild C: World cancer report 2014. World Health Organization, Geneva
23. Sung Y, Lue N, Hamza B, Martel J, Irimia D, Dasari RR, Choi W, Yaqoob Z, So P (2014) Three-dimensional holographic refractive-index measurement of continuously flowing cells in a microfluidic channel. Phys Rev Appl 1(1):014002. doi:10.1103/PhysRevApplied.1.014002
24. Terstappen LW, Johnsen S, Segers-Nolten IM, Loken MR (1990) Identification and characterization of plasma cells in normal human bone marrow by high-resolution flow cytometry. Blood 76(9):1739–1747
25. Terstappen LW, Safford M, Knemann S, Loken M, Zurlutter K, Bchner T, Hiddemann W, Wrmann B (1992) Flow cytometric characterization of acute myeloid leukemia. Part II. Phenotypic heterogeneity at diagnosis. Leukemia 6(1):70–80
26. Walts AE, Thomas P (2002) Endometrial cells and the AutoPap system for primary screening of cervicovaginal Pap smears. Diagn Cytopathol 27(4):232–237. doi:10.1002/dc.10175
27. Wu J, Li J, Chan RK (2013) A light sheet based high throughput 3D-imaging flow cytometer for phytoplankton analysis. Opt Express 21(12):14474–14480. doi:10.1364/OE.21.014474
28. Xia Y, Whitesides GM (1998) Soft lithography. Annu Rev Mater Sci 28(1):153–184. doi:10.1146/annurev.matsci.28.1.153
29. Yan Y, Boey D, Ng LT, Gruber J, Bettiol A, Thakor NV, Chen CH (2016) Continuous-flow C. elegans fluorescence expression analysis with real-time image processing through microfluidics. Biosens Bioelectron 77:428–434. doi:10.1016/j.bios.2015.09.045
30. Yang J, Zhang D, Frangi A, Yang JY (2004) Two-dimensional PCA: a new approach to appearance-based face representation and recognition. IEEE Trans Pattern Anal Mach Intell 26(1):131–137. doi:10.1109/TPAMI.2004.1261097