Isolation and Structure Elucidation of Cytotoxic Saccharothriolides D to F from a Rare Actinomycete Saccharothrix sp. and Their Structure-Activity Relationship

Journal of Natural Products

Volumn 79, Issue 7, 2016, Pages 1891-1895

  Lu, Shan ^a   Nishimura, Shinichi ^a   Ito, Masashi ^b   Tsuchida, Toshio ^b   Kakeya, Hideaki ^a  

^a KYOTO UNIVERSITY   (Japan)

^b MicroBiopharm Japan Co Ltd   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DOXORUBICIN; HYDROXYL GROUP; MACROLIDE; SACCHAROTHRIOLIDE A; SACCHAROTHRIOLIDE B; SACCHAROTHRIOLIDE D; SACCHAROTHRIOLIDE E; SACCHAROTHRIOLIDE F; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT;

ACTINOBACTERIA; ARTICLE; BACTERIUM ISOLATION; CELL GROWTH; DEMETHYLATION; DRUG DETERMINATION; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; EPIMER; FIBROSARCOMA CELL; HIGH RESOLUTION ELECTROSPRAY IONIZATION MASS SPECTROMETRY; HUMAN; HUMAN CELL; NUCLEAR MAGNETIC RESONANCE; SACCHAROTHRIX; SPECTROSCOPY; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; ACTINOMYCETALES; CHEMICAL STRUCTURE; CHEMISTRY; DRUG SCREENING; ISOLATION AND PURIFICATION;

ACTINOMYCETALES; ANTINEOPLASTIC AGENTS; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MACROLIDES; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84979499862     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/acs.jnatprod.6b00372     Document Type: Article

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