Ammocidin, a new apoptosis inducer in Ras-dependent cells from Saccharothrix sp. I. Production, isolation and biological activity

Journal of Antibiotics

Volumn 54, Issue 9, 2001, Pages 710-713

  Murakami, R ^a   Tomikawa, T ^a   Shin Ya, K ^a   Shinozaki, J ^a   Kajiura, T ^a   Kinoshita, T ^a   Miyajima, A ^a   Seto, H ^a   Hayakawa, Y ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMMOCIDIN; APOPTOSIS INDUCING FACTOR; INTERLEUKIN 3; MITOGEN ACTIVATED PROTEIN KINASE; RAS PROTEIN; S6 KINASE; UNCLASSIFIED DRUG;

ACTINOBACTERIA; ANIMAL CELL; ARTICLE; B LYMPHOCYTE; BACTERIUM CULTURE; CELL DEATH; CELL GROWTH; CELL LINE; CELL VIABILITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG ISOLATION; DRUG STRUCTURE; ENZYME PHOSPHORYLATION; IC 50; MOUSE; NONHUMAN; PRIORITY JOURNAL;

SACCHAROTHRIX;

EID: 0034787856     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.54.710     Document Type: Article

References (12)

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4. Oncogenic K-Ras and basic fibroblast growth factor prevent Fas-mediated apoptosis in fibroblasts through activation of mitogen-activated protein kinase
5. Ammocidin, a new apoptosis inducer in Ras-dependent cells from Saccharothrix sp. II. Physico-chemical properties and structure elucidation
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12. Raf/MAPK and rapamycin-sensitive pathways mediate the anti-apoptotic function of p21Ras in IL-3-dependent hematopoietic cells