Type v CRISPR-Cas Cpf1 endonuclease employs a unique mechanism for crRNA-mediated target DNA recognition

Cell Research

Volumn 26, Issue 8, 2016, Pages 901-913

  Gao, Pu ^a,b   Yang, Hui ^b   Rajashankar, Kanagalaghatta R ^c,d   Huang, Zhiwei ^e   Patel, Dinshaw J ^b  

^a INSTITUTE OF BIOPHYSICS   (China)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c Department of Molecular Biology and Genetics   (United States)

^d ARGONNE NATIONAL LABORATORY   (United States)

^e HARBIN INSTITUTE OF TECHNOLOGY   (China)

Author keywords

Cpf1; CRISPR Cas; crRNA; genome editing

Indexed keywords

DEOXYRIBONUCLEASE (PYRIMIDINE DIMER); DNA; PROTEIN BINDING; RNA;

CHEMISTRY; CONFORMATION; CRISPR CAS SYSTEM; ENZYME ACTIVE SITE; GENETICS; METABOLISM; MOLECULAR MODEL; NUCLEOTIDE SEQUENCE; PROTEIN MOTIF;

AMINO ACID MOTIFS; BASE SEQUENCE; CATALYTIC DOMAIN; CRISPR-CAS SYSTEMS; DEOXYRIBONUCLEASE (PYRIMIDINE DIMER); DNA; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; RNA;

EID: 84979224039     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2016.88     Document Type: Article

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