메뉴 건너뛰기




Volumn 94, Issue 5, 2016, Pages e305-e311

Intravitreal triamcinolone acetonide, retinal microglia and retinal ganglion cell apoptosis in the optic nerve crush model

Author keywords

intravitreal triamcinolone; optic nerve; optic nerve crush; retinal ganglion cells; retinal microglial cells

Indexed keywords

EOSIN; HEMATOXYLIN; PHOSPHATE BUFFERED SALINE; TRIAMCINOLONE ACETONIDE;

EID: 84978933440     PISSN: 1755375X     EISSN: 17553768     Source Type: Journal    
DOI: 10.1111/aos.12698     Document Type: Article
Times cited : (16)

References (40)
  • 1
    • 0032529103 scopus 로고    scopus 로고
    • Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin
    • Barber AJ, Lieth E, Khin SA, Antonetti DA, Buchanan AG & Gardner TW (1998): Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin. J Clin Invest 102: 783–791.
    • (1998) J Clin Invest , vol.102 , pp. 783-791
    • Barber, A.J.1    Lieth, E.2    Khin, S.A.3    Antonetti, D.A.4    Buchanan, A.G.5    Gardner, T.W.6
  • 2
    • 0037398304 scopus 로고    scopus 로고
    • Intraocular concentration and pharmacokinetics of triamcinolone acetonide after a single intravitreal injection
    • Beer PM, Bakri SJ, Singh RJ, Liu W, Peters GB III & Miller M (2003): Intraocular concentration and pharmacokinetics of triamcinolone acetonide after a single intravitreal injection. Ophthalmology 110: 681–686.
    • (2003) Ophthalmology , vol.110 , pp. 681-686
    • Beer, P.M.1    Bakri, S.J.2    Singh, R.J.3    Liu, W.4    Peters, G.B.5    Miller, M.6
  • 3
    • 0032935469 scopus 로고    scopus 로고
    • Unilateral injury to the adult rat optic nerve causes multiple cellular responses in the contralateral site
    • Bodeutsch N, Siebert H, Dermon C & Thanos S (1999): Unilateral injury to the adult rat optic nerve causes multiple cellular responses in the contralateral site. J Neurobiol 38: 116–128.
    • (1999) J Neurobiol , vol.38 , pp. 116-128
    • Bodeutsch, N.1    Siebert, H.2    Dermon, C.3    Thanos, S.4
  • 4
    • 67349169793 scopus 로고    scopus 로고
    • Investigating structural and biochemical correlates of ganglion cell dysfunction in streptozotocin-induced diabetic rats
    • Bui BV, Loeliger M, Thomas M, Vingrys AJ, Rees SM, Nguyen CT, He Z & Tolcos M (2009): Investigating structural and biochemical correlates of ganglion cell dysfunction in streptozotocin-induced diabetic rats. Exp Eye Res 88: 1076–1083.
    • (2009) Exp Eye Res , vol.88 , pp. 1076-1083
    • Bui, B.V.1    Loeliger, M.2    Thomas, M.3    Vingrys, A.J.4    Rees, S.M.5    Nguyen, C.T.6    He, Z.7    Tolcos, M.8
  • 5
    • 79960189557 scopus 로고    scopus 로고
    • Glial cell response and iNOS expression in the optic nerve head and retina of the rat following acute high IOP ischemia-reperfusion
    • Cho KJ, Kim JH, Park HY & Park CK (2011): Glial cell response and iNOS expression in the optic nerve head and retina of the rat following acute high IOP ischemia-reperfusion. Brain Res 1403: 67–77.
    • (2011) Brain Res , vol.1403 , pp. 67-77
    • Cho, K.J.1    Kim, J.H.2    Park, H.Y.3    Park, C.K.4
  • 6
    • 0028819936 scopus 로고
    • Release of anti-inflammatory mediators after mechanical trauma correlates with severity of injury and clinical outcome
    • Ertel W, Keel M, Bonaccio M, Steckholzer U, Gallati H, Kenney JS & Trentz O (1995): Release of anti-inflammatory mediators after mechanical trauma correlates with severity of injury and clinical outcome. J Trauma 39: 879–885.
    • (1995) J Trauma , vol.39 , pp. 879-885
    • Ertel, W.1    Keel, M.2    Bonaccio, M.3    Steckholzer, U.4    Gallati, H.5    Kenney, J.S.6    Trentz, O.7
  • 7
    • 0031934936 scopus 로고    scopus 로고
    • Microglia-derived nerve growth factor causes cell death in the developing retina
    • Frade JM & Barde YA (1998): Microglia-derived nerve growth factor causes cell death in the developing retina. Neuron 20: 35–41.
    • (1998) Neuron , vol.20 , pp. 35-41
    • Frade, J.M.1    Barde, Y.A.2
  • 8
    • 34147198831 scopus 로고    scopus 로고
    • Drug-induced ocular inflammatory diseases
    • Fraunfelder FW (2007): Drug-induced ocular inflammatory diseases. Drugs Today (Barc) 43: 117–123.
    • (2007) Drugs Today (Barc) , vol.43 , pp. 117-123
    • Fraunfelder, F.W.1
  • 11
    • 35548986304 scopus 로고    scopus 로고
    • Microglia: active sensor and versatile effector cells in the normal and pathologic brain
    • Hanisch UK & Kettenmann H (2007): Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat Neurosci 10: 1387–1394.
    • (2007) Nat Neurosci , vol.10 , pp. 1387-1394
    • Hanisch, U.K.1    Kettenmann, H.2
  • 12
    • 0036850873 scopus 로고    scopus 로고
    • Microglia-Muller glia cell interactions control neurotrophic factor production during light-induced retinal degeneration
    • Harada T, Harada C, Kohsaka S et al. (2002): Microglia-Muller glia cell interactions control neurotrophic factor production during light-induced retinal degeneration. J Neurosci 22: 9228–9236.
    • (2002) J Neurosci , vol.22 , pp. 9228-9236
    • Harada, T.1    Harada, C.2    Kohsaka, S.3
  • 13
    • 84868091439 scopus 로고    scopus 로고
    • Identification and characterization of triamcinolone acetonide, a microglial-activation inhibitor
    • Hong J, Kim BK, Lim H, Lee S & Lee SJ (2012): Identification and characterization of triamcinolone acetonide, a microglial-activation inhibitor. Immunopharmacol Immunotoxicol 34: 912–918.
    • (2012) Immunopharmacol Immunotoxicol , vol.34 , pp. 912-918
    • Hong, J.1    Kim, B.K.2    Lim, H.3    Lee, S.4    Lee, S.J.5
  • 14
    • 79451468770 scopus 로고    scopus 로고
    • Lack of protective effect of local administration of triamcinolone or systemic treatment with methylprednisolone against damages caused by optic nerve crush in rats
    • Huang TL, Chang CH, Lin KH, Sheu MM & Tsai RK (2011): Lack of protective effect of local administration of triamcinolone or systemic treatment with methylprednisolone against damages caused by optic nerve crush in rats. Exp Eye Res 92: 112–119.
    • (2011) Exp Eye Res , vol.92 , pp. 112-119
    • Huang, T.L.1    Chang, C.H.2    Lin, K.H.3    Sheu, M.M.4    Tsai, R.K.5
  • 15
    • 29244448689 scopus 로고    scopus 로고
    • Intravitreal triamcinolone acetonide for treatment of intraocular oedematous and neovascular diseases
    • Jonas JB (2005): Intravitreal triamcinolone acetonide for treatment of intraocular oedematous and neovascular diseases. Acta Ophthalmol Scand 83: 645–663.
    • (2005) Acta Ophthalmol Scand , vol.83 , pp. 645-663
    • Jonas, J.B.1
  • 16
    • 84857406614 scopus 로고    scopus 로고
    • The spider effect: morphological and orienting classification of microglia in response to stimuli in vivo
    • Jonas RA, Yuan TF, Liang YX, Jonas JB, Tay DK & Ellis-Behnke RG (2012): The spider effect: morphological and orienting classification of microglia in response to stimuli in vivo. PLoS ONE 7: e30763.
    • (2012) PLoS ONE , vol.7
    • Jonas, R.A.1    Yuan, T.F.2    Liang, Y.X.3    Jonas, J.B.4    Tay, D.K.5    Ellis-Behnke, R.G.6
  • 17
    • 34548845583 scopus 로고    scopus 로고
    • Triamcinolone acetonide protects the rat retina from STZ-induced acute inflammation and early vascular leakage
    • Kim YH, Choi MY, Kim YS et al. (2007): Triamcinolone acetonide protects the rat retina from STZ-induced acute inflammation and early vascular leakage. Life Sci 81: 1167–1173.
    • (2007) Life Sci , vol.81 , pp. 1167-1173
    • Kim, Y.H.1    Choi, M.Y.2    Kim, Y.S.3
  • 18
    • 0033103686 scopus 로고    scopus 로고
    • Early neuronal expression of tumor necrosis factor-alpha after experimental brain injury contributes to neurological impairment
    • Knoblach SM, Fan L & Faden AI (1999): Early neuronal expression of tumor necrosis factor-alpha after experimental brain injury contributes to neurological impairment. J Neuroimmunol 95: 115–125.
    • (1999) J Neuroimmunol , vol.95 , pp. 115-125
    • Knoblach, S.M.1    Fan, L.2    Faden, A.I.3
  • 19
    • 17844392902 scopus 로고    scopus 로고
    • Minocycline reduces proinflammatory cytokine expression, microglial activation, and caspase-3 activation in a rodent model of diabetic retinopathy
    • Krady JK, Basu A, Allen CM, Xu Y, LaNoue KF, Gardner TW & Levison SW (2005): Minocycline reduces proinflammatory cytokine expression, microglial activation, and caspase-3 activation in a rodent model of diabetic retinopathy. Diabetes 54: 1559–1565.
    • (2005) Diabetes , vol.54 , pp. 1559-1565
    • Krady, J.K.1    Basu, A.2    Allen, C.M.3    Xu, Y.4    LaNoue, K.F.5    Gardner, T.W.6    Levison, S.W.7
  • 21
    • 84871696092 scopus 로고    scopus 로고
    • Tracking retinal microgliosis in models of retinal ganglion cell damage
    • Liu S, Li ZW, Weinreb RN et al. (2012): Tracking retinal microgliosis in models of retinal ganglion cell damage. Invest Ophthalmol Vis Sci 53: 6254–6262.
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , pp. 6254-6262
    • Liu, S.1    Li, Z.W.2    Weinreb, R.N.3
  • 22
    • 30444459031 scopus 로고    scopus 로고
    • The role of inflammation in CNS injury and disease
    • Lucas SM, Rothwell NJ & Gibson RM (2006): The role of inflammation in CNS injury and disease. Br J Pharmacol 147(Suppl. 1): S232–S240.
    • (2006) Br J Pharmacol , vol.147 , pp. S232-S240
    • Lucas, S.M.1    Rothwell, N.J.2    Gibson, R.M.3
  • 23
    • 58249121841 scopus 로고    scopus 로고
    • Effect of brimonidine on retinal ganglion cell survival in an optic nerve crush model
    • Ma K, Xu L, Zhang H, Zhang S, Pu M & Jonas JB (2009): Effect of brimonidine on retinal ganglion cell survival in an optic nerve crush model. Am J Ophthalmol 147: 326–331.
    • (2009) Am J Ophthalmol , vol.147 , pp. 326-331
    • Ma, K.1    Xu, L.2    Zhang, H.3    Zhang, S.4    Pu, M.5    Jonas, J.B.6
  • 24
    • 0029996739 scopus 로고    scopus 로고
    • The concept of microglia in relation to central nervous system disease and regeneration
    • Moore S & Thanos S (1996): The concept of microglia in relation to central nervous system disease and regeneration. Prog Neurobiol 48: 441–460.
    • (1996) Prog Neurobiol , vol.48 , pp. 441-460
    • Moore, S.1    Thanos, S.2
  • 26
    • 77952189143 scopus 로고    scopus 로고
    • Characterisation of systemic and ocular drug level of triamcinolone acetonide following a single sub-Tenon injection
    • Nan K, Sun S, Li Y, Qu J, Li G, Luo L, Chen H & Cheng L (2010): Characterisation of systemic and ocular drug level of triamcinolone acetonide following a single sub-Tenon injection. Br J Ophthalmol 94: 654–658.
    • (2010) Br J Ophthalmol , vol.94 , pp. 654-658
    • Nan, K.1    Sun, S.2    Li, Y.3    Qu, J.4    Li, G.5    Luo, L.6    Chen, H.7    Cheng, L.8
  • 27
    • 0141788998 scopus 로고    scopus 로고
    • Complement activation following optic nerve crush in the adult rat
    • Ohlsson M, Bellander BM, Langmoen IA & Svensson M (2003): Complement activation following optic nerve crush in the adult rat. J Neurotrauma 20: 895–904.
    • (2003) J Neurotrauma , vol.20 , pp. 895-904
    • Ohlsson, M.1    Bellander, B.M.2    Langmoen, I.A.3    Svensson, M.4
  • 28
    • 0034945431 scopus 로고    scopus 로고
    • Effects of triamcinolone acetonide on microglial morphology and quantitative expression of MHC-II in exudative age-related macular degeneration
    • Penfold PL, Wong JG, Gyory J & Billson FA (2001): Effects of triamcinolone acetonide on microglial morphology and quantitative expression of MHC-II in exudative age-related macular degeneration. Clin Experiment Ophthalmol 29: 188–192.
    • (2001) Clin Experiment Ophthalmol , vol.29 , pp. 188-192
    • Penfold, P.L.1    Wong, J.G.2    Gyory, J.3    Billson, F.A.4
  • 30
    • 77649190127 scopus 로고    scopus 로고
    • Triamcinolone attenuates macrophage/microglia accumulation associated with NMDA-induced RGC death and facilitates survival of Muller stem cell grafts
    • Singhal S, Lawrence JM, Salt TE, Khaw PT & Limb GA (2010): Triamcinolone attenuates macrophage/microglia accumulation associated with NMDA-induced RGC death and facilitates survival of Muller stem cell grafts. Exp Eye Res 90: 308–315.
    • (2010) Exp Eye Res , vol.90 , pp. 308-315
    • Singhal, S.1    Lawrence, J.M.2    Salt, T.E.3    Khaw, P.T.4    Limb, G.A.5
  • 31
    • 4744370909 scopus 로고    scopus 로고
    • Microglia-derived pronerve growth factor promotes photoreceptor cell death via p75 neurotrophin receptor
    • Srinivasan B, Roque CH, Hempstead BL, Al-Ubaidi MR & Roque RS (2004): Microglia-derived pronerve growth factor promotes photoreceptor cell death via p75 neurotrophin receptor. J Biol Chem 279: 41839–41845.
    • (2004) J Biol Chem , vol.279 , pp. 41839-41845
    • Srinivasan, B.1    Roque, C.H.2    Hempstead, B.L.3    Al-Ubaidi, M.R.4    Roque, R.S.5
  • 32
    • 83555174832 scopus 로고    scopus 로고
    • Sustained axon regeneration induced by co-deletion of PTEN and SOCS3
    • Sun F, Park KK, Belin S et al. (2011): Sustained axon regeneration induced by co-deletion of PTEN and SOCS3. Nature 480: 372–375.
    • (2011) Nature , vol.480 , pp. 372-375
    • Sun, F.1    Park, K.K.2    Belin, S.3
  • 33
    • 0346102799 scopus 로고    scopus 로고
    • Role of tumor necrosis factor receptor-1 in the death of retinal ganglion cells following optic nerve crush injury in mice
    • Tezel G, Yang X, Yang J & Wax MB (2004): Role of tumor necrosis factor receptor-1 in the death of retinal ganglion cells following optic nerve crush injury in mice. Brain Res 996: 202–212.
    • (2004) Brain Res , vol.996 , pp. 202-212
    • Tezel, G.1    Yang, X.2    Yang, J.3    Wax, M.B.4
  • 34
    • 0027464886 scopus 로고
    • Treatment of the adult retina with microglia-suppressing factors retards axotomy-induced neuronal degradation and enhances axonal regeneration in vivo and in vitro
    • Thanos S, Mey J & Wild M (1993): Treatment of the adult retina with microglia-suppressing factors retards axotomy-induced neuronal degradation and enhances axonal regeneration in vivo and in vitro. J Neurosci 13: 455–466.
    • (1993) J Neurosci , vol.13 , pp. 455-466
    • Thanos, S.1    Mey, J.2    Wild, M.3
  • 35
    • 84865589482 scopus 로고    scopus 로고
    • Blocking endothelin-B receptors rescues retinal ganglion cells from optic nerve injury through suppression of neuroinflammation
    • Tonari M, Kurimoto T, Horie T, Sugiyama T, Ikeda T & Oku H (2012): Blocking endothelin-B receptors rescues retinal ganglion cells from optic nerve injury through suppression of neuroinflammation. Invest Ophthalmol Vis Sci 53: 3490–3500.
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , pp. 3490-3500
    • Tonari, M.1    Kurimoto, T.2    Horie, T.3    Sugiyama, T.4    Ikeda, T.5    Oku, H.6
  • 36
    • 50849141076 scopus 로고    scopus 로고
    • Neuroprotective effects of recombinant human granulocyte colony-stimulating factor (G-CSF) in neurodegeneration after optic nerve crush in rats
    • Tsai RK, Chang CH & Wang HZ (2008): Neuroprotective effects of recombinant human granulocyte colony-stimulating factor (G-CSF) in neurodegeneration after optic nerve crush in rats. Exp Eye Res 87: 242–250.
    • (2008) Exp Eye Res , vol.87 , pp. 242-250
    • Tsai, R.K.1    Chang, C.H.2    Wang, H.Z.3
  • 37
    • 84876082764 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor is retinal ganglion cell neuroprotective and axogenic after optic nerve crush injury
    • Vigneswara V, Berry M, Logan A & Ahmed Z (2013): Pigment epithelium-derived factor is retinal ganglion cell neuroprotective and axogenic after optic nerve crush injury. Invest Ophthalmol Vis Sci 54: 2624–2633.
    • (2013) Invest Ophthalmol Vis Sci , vol.54 , pp. 2624-2633
    • Vigneswara, V.1    Berry, M.2    Logan, A.3    Ahmed, Z.4
  • 38
    • 0033781980 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha: a potentially neurodestructive cytokine produced by glia in the human glaucomatous optic nerve head
    • Yuan L & Neufeld AH (2000): Tumor necrosis factor-alpha: a potentially neurodestructive cytokine produced by glia in the human glaucomatous optic nerve head. Glia 2: 42–50.
    • (2000) Glia , vol.2 , pp. 42-50
    • Yuan, L.1    Neufeld, A.H.2
  • 39
    • 79958081680 scopus 로고    scopus 로고
    • Neuroprotective effect of intravitreal cell-based glucagon-like peptide-1 production in the optic nerve crush model
    • Zhang R, Zhang H, Xu L, Ma K, Wallrapp C & Jonas JB (2011): Neuroprotective effect of intravitreal cell-based glucagon-like peptide-1 production in the optic nerve crush model. Acta Ophthalmol 89: e320–e326.
    • (2011) Acta Ophthalmol , vol.89 , pp. e320-e326
    • Zhang, R.1    Zhang, H.2    Xu, L.3    Ma, K.4    Wallrapp, C.5    Jonas, J.B.6
  • 40
    • 84869490391 scopus 로고    scopus 로고
    • The toll-like receptor 4-mediated signaling pathway is activated following optic nerve injury in mice
    • Zheng Z, Yuan R, Song M et al. (2012): The toll-like receptor 4-mediated signaling pathway is activated following optic nerve injury in mice. Brain Res 1489: 90–97.
    • (2012) Brain Res , vol.1489 , pp. 90-97
    • Zheng, Z.1    Yuan, R.2    Song, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.