메뉴 건너뛰기




Volumn 16, Issue 1, 2016, Pages

Relevance of miR-21 in regulation of tumor suppressor gene PTEN in human cervical cancer cells

Author keywords

Cervical cancer; MicroRNAs; MiR 21; PTEN; SiRNAs

Indexed keywords

MICRORNA 21; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; MICRORNA; MIRN21 MICRORNA, HUMAN; PTEN PROTEIN, HUMAN; SMALL INTERFERING RNA;

EID: 84978878135     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/s12885-016-2231-3     Document Type: Article
Times cited : (81)

References (70)
  • 1
    • 33644768174 scopus 로고    scopus 로고
    • Control of translation and mRNA degradation by miRNAs and siRNAs
    • Valencia-Sanchez MA, Liu J, Hannon GJ, Parker R. Control of translation and mRNA degradation by miRNAs and siRNAs. Genes Dev. 2006;20:515-24.
    • (2006) Genes Dev , vol.20 , pp. 515-524
    • Valencia-Sanchez, M.A.1    Liu, J.2    Hannon, G.J.3    Parker, R.4
  • 2
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • Chan JA, Krichevsky AM, Kosik KS. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res. 2005;65:6029-33.
    • (2005) Cancer Res , vol.65 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 5
    • 63449126920 scopus 로고    scopus 로고
    • MicroRNA-21 regulates the proliferation and invasion in esophageal squamous cell carcinoma
    • Hiyoshi Y, Kamohara H, Karashima R, Sato N, Imamura Y, Nagai Y, et al. MicroRNA-21 regulates the proliferation and invasion in esophageal squamous cell carcinoma. Clin Cancer Res. 2009;15(6):1915-22.
    • (2009) Clin Cancer Res , vol.15 , Issue.6 , pp. 1915-1922
    • Hiyoshi, Y.1    Kamohara, H.2    Karashima, R.3    Sato, N.4    Imamura, Y.5    Nagai, Y.6
  • 6
    • 42549169404 scopus 로고    scopus 로고
    • MiR-21 microRNA expression in human gastric carcinomas and its clinical association
    • Chan SH, Wu CW, Li AF, Chi CW, Lin WC. MiR-21 microRNA expression in human gastric carcinomas and its clinical association. Anticancer Res. 2008;28:907-11.
    • (2008) Anticancer Res , vol.28 , pp. 907-911
    • Chan, S.H.1    Wu, C.W.2    Li, A.F.3    Chi, C.W.4    Lin, W.C.5
  • 7
    • 34547524771 scopus 로고    scopus 로고
    • MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
    • Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST, Patel T. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology. 2007;133:647-58.
    • (2007) Gastroenterology , vol.133 , pp. 647-658
    • Meng, F.1    Henson, R.2    Wehbe-Janek, H.3    Ghoshal, K.4    Jacob, S.T.5    Patel, T.6
  • 8
    • 33744521896 scopus 로고    scopus 로고
    • Involvement of human Micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines
    • Meng F, Henson R, Lang M, Wehbe H, Maheshwari S, Mendell JT, et al. Involvement of human Micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines. Gastroenterology. 2006;130(7):2113-29.
    • (2006) Gastroenterology , vol.130 , Issue.7 , pp. 2113-2129
    • Meng, F.1    Henson, R.2    Lang, M.3    Wehbe, H.4    Maheshwari, S.5    Mendell, J.T.6
  • 9
    • 66849124564 scopus 로고    scopus 로고
    • MicroRNA-21 modulates biological functions of pancreatic cancer cells including their proliferation, invasion, and chemoresistance
    • Moriyama T, Ohuchida K, Mizumoto K, Yu J, Sato N, Nabae T, et al. MicroRNA-21 modulates biological functions of pancreatic cancer cells including their proliferation, invasion, and chemoresistance. Mol Cancer Ther. 2009;8(5):1067-74.
    • (2009) Mol Cancer Ther , vol.8 , Issue.5 , pp. 1067-1074
    • Moriyama, T.1    Ohuchida, K.2    Mizumoto, K.3    Yu, J.4    Sato, N.5    Nabae, T.6
  • 11
    • 70350536585 scopus 로고    scopus 로고
    • Distinct microRNA alterations characterize highand low-grade bladder cancer
    • Catto JW, Miah S, Owen HC, Bryant H, Myers K, Dudziec E, et al. Distinct microRNA alterations characterize highand low-grade bladder cancer. Cancer Res. 2009;69(21):8472-81.
    • (2009) Cancer Res , vol.69 , Issue.21 , pp. 8472-8481
    • Catto, J.W.1    Miah, S.2    Owen, H.C.3    Bryant, H.4    Myers, K.5    Dudziec, E.6
  • 13
    • 70350457646 scopus 로고    scopus 로고
    • Aberrant overexpression of microRNAs activate AKT signaling via downregulation of tumor suppressors in NK-cell lymphoma/leukemia
    • Yamanaka Y, Tagawa H, Takahashi N, Watanabe A, Guo YM, Iwamoto K, et al. Aberrant overexpression of microRNAs activate AKT signaling via downregulation of tumor suppressors in NK-cell lymphoma/leukemia. Blood. 2009;114(15):3265-75.
    • (2009) Blood , vol.114 , Issue.15 , pp. 3265-3275
    • Yamanaka, Y.1    Tagawa, H.2    Takahashi, N.3    Watanabe, A.4    Guo, Y.M.5    Iwamoto, K.6
  • 14
    • 68149137764 scopus 로고    scopus 로고
    • Regulation of the cell cycle gene, BTG2, by miR-21 in human laryngeal carcinoma
    • Liu M, Wu H, Liu T, Li Y, Wang F, Wan H, et al. Regulation of the cell cycle gene, BTG2, by miR-21 in human laryngeal carcinoma. Cell Res. 2009;19(7):828-37.
    • (2009) Cell Res , vol.19 , Issue.7 , pp. 828-837
    • Liu, M.1    Wu, H.2    Liu, T.3    Li, Y.4    Wang, F.5    Wan, H.6
  • 15
    • 67449164586 scopus 로고    scopus 로고
    • MiR-21 indicates poor prognosis in tongue squamous cell carcinomas as an apoptosis inhibitor
    • Li J, Huang H, Sun L, Yang M, Pan C, Chen W, et al. MiR-21 indicates poor prognosis in tongue squamous cell carcinomas as an apoptosis inhibitor. Clin Cancer Res. 2009;15(12):3998-4008.
    • (2009) Clin Cancer Res , vol.15 , Issue.12 , pp. 3998-4008
    • Li, J.1    Huang, H.2    Sun, L.3    Yang, M.4    Pan, C.5    Chen, W.6
  • 16
    • 77956339881 scopus 로고    scopus 로고
    • OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma
    • Medina PP, Nolde M, Slack FJ. OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma. Nature. 2010;467:86-90.
    • (2010) Nature , vol.467 , pp. 86-90
    • Medina, P.P.1    Nolde, M.2    Slack, F.J.3
  • 17
    • 43449111804 scopus 로고    scopus 로고
    • Cloning and characterization of microRNAs from rainbow trout (Oncorhynchus mykiss): their expression during early embryonic development
    • Ramachandra RK, Salem M, Gahr S, Rexroad 3rd CE, Yao J. Cloning and characterization of microRNAs from rainbow trout (Oncorhynchus mykiss): their expression during early embryonic development. BMC Dev Biol. 2008;8:41.
    • (2008) BMC Dev Biol , vol.8 , pp. 41
    • Ramachandra, R.K.1    Salem, M.2    Gahr, S.3    Rexroad, C.E.4    Yao, J.5
  • 18
    • 77955404450 scopus 로고    scopus 로고
    • MicroRNA 21 blocks apoptosis in mouse periovulatory granulose cells
    • Carletti MZ, Fiedler SD, Christenson LK. MicroRNA 21 blocks apoptosis in mouse periovulatory granulose cells. Biol Reprod. 2010;83:286-95.
    • (2010) Biol Reprod , vol.83 , pp. 286-295
    • Carletti, M.Z.1    Fiedler, S.D.2    Christenson, L.K.3
  • 19
  • 20
    • 69049120925 scopus 로고    scopus 로고
    • High miR-21 expression in breast cancer associated with poor disease-free survival in early stage disease and high TGFbeta1
    • Qian B, Katsaros D, Lu L, Preti M, Durando A, Arisio R, et al. High miR-21 expression in breast cancer associated with poor disease-free survival in early stage disease and high TGFbeta1. Breast Cancer Res Treat. 2009;117(1):131-40.
    • (2009) Breast Cancer Res Treat , vol.117 , Issue.1 , pp. 131-140
    • Qian, B.1    Katsaros, D.2    Lu, L.3    Preti, M.4    Durando, A.5    Arisio, R.6
  • 22
    • 54049115558 scopus 로고    scopus 로고
    • Prognostic value of mature microRNA-21 and microRNA-205 overexpression in non-small cell lung cancer by quantitative realtime RT-PCR
    • Markou A, Tsaroucha EG, Kaklamanis L, Fotinou M, Georgoulias V, Lianidou ES. Prognostic value of mature microRNA-21 and microRNA-205 overexpression in non-small cell lung cancer by quantitative realtime RT-PCR. Clin Chem. 2008;54(10):1696-704.
    • (2008) Clin Chem , vol.54 , Issue.10 , pp. 1696-1704
    • Markou, A.1    Tsaroucha, E.G.2    Kaklamanis, L.3    Fotinou, M.4    Georgoulias, V.5    Lianidou, E.S.6
  • 23
    • 72449187466 scopus 로고    scopus 로고
    • Altered miRNA expression in sputum for diagnosis of non-small cell lung cancer
    • Xie Y, Todd NW, Liu Z, Zhan M, Fang H, Peng H, et al. Altered miRNA expression in sputum for diagnosis of non-small cell lung cancer. Lung Cancer. 2010;67(2):170-6.
    • (2010) Lung Cancer , vol.67 , Issue.2 , pp. 170-176
    • Xie, Y.1    Todd, N.W.2    Liu, Z.3    Zhan, M.4    Fang, H.5    Peng, H.6
  • 24
    • 77954315239 scopus 로고    scopus 로고
    • Deregulated expression of miR-21, miR-143 and miR-181a in non- small cell lung cancer is related to clinicopathologic characteristics or patient prognosis
    • Gao W, Yu Y, Cao H, Shen H, Li X, Pan S, et al. Deregulated expression of miR-21, miR-143 and miR-181a in non- small cell lung cancer is related to clinicopathologic characteristics or patient prognosis. Biomed Pharmacother. 2010;64(6):399-408.
    • (2010) Biomed Pharmacother , vol.64 , Issue.6 , pp. 399-408
    • Gao, W.1    Yu, Y.2    Cao, H.3    Shen, H.4    Li, X.5    Pan, S.6
  • 25
    • 84928752251 scopus 로고    scopus 로고
    • MicroRNA-21 is a candidate driver gene for 17q23-25 amplification in ovarian clear cell carcinoma
    • Hirata Y, Murai N, Yanaihara N, Saito M, Saito M, Urashima M, et al. MicroRNA-21 is a candidate driver gene for 17q23-25 amplification in ovarian clear cell carcinoma. BMC Cancer. 2014;14:799.
    • (2014) BMC Cancer , vol.14 , pp. 799
    • Hirata, Y.1    Murai, N.2    Yanaihara, N.3    Saito, M.4    Saito, M.5    Urashima, M.6
  • 27
    • 54249136806 scopus 로고    scopus 로고
    • MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells
    • Papagiannakopoulos T, Shapiro A, Kosik KS. MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. Cancer Res. 2008;68:8164-72.
    • (2008) Cancer Res , vol.68 , pp. 8164-8172
    • Papagiannakopoulos, T.1    Shapiro, A.2    Kosik, K.S.3
  • 28
    • 77956061393 scopus 로고    scopus 로고
    • MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC)
    • Zhang JG, Wang JJ, Zhao F, Liu Q, Jiang K, Yang GH. MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC). Clin Chim Acta. 2010;411(11-12):846-52.
    • (2010) Clin Chim Acta , vol.411 , Issue.11-12 , pp. 846-852
    • Zhang, J.G.1    Wang, J.J.2    Zhao, F.3    Liu, Q.4    Jiang, K.5    Yang, G.H.6
  • 29
    • 41749113108 scopus 로고    scopus 로고
    • MicroRNA-21 (miR-21) posttranscriptionally down-regulates tumor suppressor PDCD4 and stimulates invasion, intravasation and metastasis in colorectal cancer
    • Asangani IA, Rasheed SA, Nikolova DA, Leupold JH, Colburn NH, Post S, et al. MicroRNA-21 (miR-21) posttranscriptionally down-regulates tumor suppressor PDCD4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene. 2007;27:2128-36.
    • (2007) Oncogene , vol.27 , pp. 2128-2136
    • Asangani, I.A.1    Rasheed, S.A.2    Nikolova, D.A.3    Leupold, J.H.4    Colburn, N.H.5    Post, S.6
  • 30
    • 40249092910 scopus 로고    scopus 로고
    • MicroRNA-21 targets tumor suppressor genes in invasion and metastasis
    • Zhu S, Wu H, Wu F, Nie D, Sheng S, Mo YY. MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res. 2008;18:350-9.
    • (2008) Cell Res , vol.18 , pp. 350-359
    • Zhu, S.1    Wu, H.2    Wu, F.3    Nie, D.4    Sheng, S.5    Mo, Y.Y.6
  • 31
    • 34347266556 scopus 로고    scopus 로고
    • MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1)
    • Zhu S, Si M-L, Wu H, Mo YY. MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1). J Biol Chem. 2007;282:14328-36.
    • (2007) J Biol Chem , vol.282 , pp. 14328-14336
    • Zhu, S.1    Si, M.-L.2    Wu, H.3    Mo, Y.Y.4
  • 32
    • 34447134869 scopus 로고    scopus 로고
    • Patterns of known and novel small RNAs in human cervical cancer
    • Lui WO, Pourmand N, Patterson BK, Fire A. Patterns of known and novel small RNAs in human cervical cancer. Cancer Res. 2007;67(13):6031-43.
    • (2007) Cancer Res , vol.67 , Issue.13 , pp. 6031-6043
    • Lui, W.O.1    Pourmand, N.2    Patterson, B.K.3    Fire, A.4
  • 33
    • 83255189410 scopus 로고    scopus 로고
    • MiR-21 is involved in cervical squamous cell tumorigenesis and regulates CCL20
    • Yao T, Lin Z. MiR-21 is involved in cervical squamous cell tumorigenesis and regulates CCL20. Biochim Biophys Acta. 2012;1822(2):248-60.
    • (2012) Biochim Biophys Acta , vol.1822 , Issue.2 , pp. 248-260
    • Yao, T.1    Lin, Z.2
  • 34
    • 84920381767 scopus 로고    scopus 로고
    • MicroRNA Expressions in HPV-induced Cervical Dysplasia and Cancer
    • Gocze K, Gombos K, Kovacs K, Juhasz K, Gocze P, Kiss I. MicroRNA Expressions in HPV-induced Cervical Dysplasia and Cancer. Anticancer Res. 2015;35(1):523-30.
    • (2015) Anticancer Res , vol.35 , Issue.1 , pp. 523-530
    • Gocze, K.1    Gombos, K.2    Kovacs, K.3    Juhasz, K.4    Gocze, P.5    Kiss, I.6
  • 36
    • 0036559896 scopus 로고    scopus 로고
    • Papillomaviruses and cancer: from basic studies to clinical application
    • Zur Hausen H. Papillomaviruses and cancer: from basic studies to clinical application. Nat Rev Cancer. 2002;2:342-50.
    • (2002) Nat Rev Cancer , vol.2 , pp. 342-350
    • Zur Hausen, H.1
  • 37
    • 0038261924 scopus 로고    scopus 로고
    • Human papillomavirus, it's genes. and cancer vaccines
    • Steller MA. Human papillomavirus, it's genes. and cancer vaccines. Cancer Cell. 2003;3(1):7-8.
    • (2003) Cancer Cell , vol.3 , Issue.1 , pp. 7-8
    • Steller, M.A.1
  • 39
    • 77953856958 scopus 로고    scopus 로고
    • Interaction of viral oncoproteins with cellular target molecules: infection with high-risk vs low-risk human papillomaviruses
    • Pim D, Banks L. Interaction of viral oncoproteins with cellular target molecules: infection with high-risk vs low-risk human papillomaviruses. APMIS. 2010;118(6-7):471-93.
    • (2010) APMIS , vol.118 , Issue.6-7 , pp. 471-493
    • Pim, D.1    Banks, L.2
  • 40
    • 80655127810 scopus 로고    scopus 로고
    • Regulation of cellular miRNA expression by human papillomaviruses
    • Zheng ZM, Wang X. Regulation of cellular miRNA expression by human papillomaviruses. Biochim Biophys Acta. 2011;1809(11-12):668-77.
    • (2011) Biochim Biophys Acta , vol.1809 , Issue.11-12 , pp. 668-677
    • Zheng, Z.M.1    Wang, X.2
  • 41
    • 84978785505 scopus 로고    scopus 로고
    • RNA Technical Resources from Ambion
    • © Thermo Fisher Scientific Inc. Accessed 31 Mar 2014.
    • Life Technology. RNA Technical Resources from Ambion. http://www.lifetechnologies.com/mx/es/home/references/ambion-techsupport.html. © 2015 Thermo Fisher Scientific Inc. Accessed 31 Mar 2014.
    • (2015)
  • 42
    • 0011197334 scopus 로고    scopus 로고
    • GeneFisher - software support for the detection of postulated genes.
    • Accessed 31 Mar 2014.
    • Giegerich R, Meyer F, Schleiermacher C. GeneFisher - software support for the detection of postulated genes. 1996. http://bibiserv.techfak.uni-bielefeld.de/genefisher2/. Accessed 31 Mar 2014.
    • (1996)
    • Giegerich, R.1    Meyer, F.2    Schleiermacher, C.3
  • 43
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods. 2001;25:402-8.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 45
    • 84978825783 scopus 로고    scopus 로고
    • TargetScanHuman and Mouse Version 6.2. June
    • Accessed 30 Apr 2014.
    • Whitehead Institute for Biomedical Research. TargetScanHuman and Mouse Version 6.2. June 2012; http://www.targetscan.org/. Accessed 30 Apr 2014.
    • (2012)
  • 46
    • 0037468256 scopus 로고    scopus 로고
    • Common fragile sites are preferential targets for HPV16 integrations in cervical tumors
    • Thorland EC, Myers SL, Gostout BS, Smith DI. Common fragile sites are preferential targets for HPV16 integrations in cervical tumors. Oncogene. 2003;22:1225-37.
    • (2003) Oncogene , vol.22 , pp. 1225-1237
    • Thorland, E.C.1    Myers, S.L.2    Gostout, B.S.3    Smith, D.I.4
  • 47
    • 4344602002 scopus 로고    scopus 로고
    • The biology and clinical relevance of the PTEN tumor suppressor pathway
    • Sansal I, Sellers WR. The biology and clinical relevance of the PTEN tumor suppressor pathway. J Clin Oncol. 2004;22(14):2954-63.
    • (2004) J Clin Oncol , vol.22 , Issue.14 , pp. 2954-2963
    • Sansal, I.1    Sellers, W.R.2
  • 48
    • 84863011293 scopus 로고    scopus 로고
    • MicroRNA-21 promotes tumor proliferation and invasion in gastric cancer by targeting PTEN
    • Zhang BG, Li JF, Yu BQ, Zhu ZG, Liu BY, Yan M. MicroRNA-21 promotes tumor proliferation and invasion in gastric cancer by targeting PTEN. Oncol Rep. 2012;4:1019-26.
    • (2012) Oncol Rep , vol.4 , pp. 1019-1026
    • Zhang, B.G.1    Li, J.F.2    Yu, B.Q.3    Zhu, Z.G.4    Liu, B.Y.5    Yan, M.6
  • 49
    • 84919474075 scopus 로고    scopus 로고
    • Disruption of microRNA-21 by TALEN leads to diminished cell transformation and increased expression of cell-environment interaction genes
    • Chen B, Chen X, Wu X, Wang X, Wang Y, Lin TY, Kurata J, et al. Disruption of microRNA-21 by TALEN leads to diminished cell transformation and increased expression of cell-environment interaction genes. Cancer Lett. 2015;356(2 Pt B):506-16.
    • (2015) Cancer Lett , vol.356 , Issue.2 , pp. 506-516
    • Chen, B.1    Chen, X.2    Wu, X.3    Wang, X.4    Wang, Y.5    Lin, T.Y.6    Kurata, J.7
  • 50
    • 84919464999 scopus 로고    scopus 로고
    • The Lilliputians and the Giant: An Emerging Oncogenic microRNA Network that Suppresses the PTEN Tumor Suppressor In Vivo
    • Tay Y, Song SJ, Pandolfi PP. The Lilliputians and the Giant: An Emerging Oncogenic microRNA Network that Suppresses the PTEN Tumor Suppressor In Vivo. Microrna. 2013;2(2):127-36.
    • (2013) Microrna , vol.2 , Issue.2 , pp. 127-136
    • Tay, Y.1    Song, S.J.2    Pandolfi, P.P.3
  • 51
    • 0036690393 scopus 로고    scopus 로고
    • PI3K blockade by Ad-PTEN inhibits invasion and induces apoptosis in radial growth phase and metastatic melanoma cells
    • Stewart AL, Mhashilkar AM, Yang XH, Ekmekcioglu S, Saito Y, Sieger K, Schrock R, et al. PI3K blockade by Ad-PTEN inhibits invasion and induces apoptosis in radial growth phase and metastatic melanoma cells. Mol Med. 2002;8:451-61.
    • (2002) Mol Med , vol.8 , pp. 451-461
    • Stewart, A.L.1    Mhashilkar, A.M.2    Yang, X.H.3    Ekmekcioglu, S.4    Saito, Y.5    Sieger, K.6    Schrock, R.7
  • 52
    • 0032486198 scopus 로고    scopus 로고
    • Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
    • Tamura M, Gu J, Matsumoto K, Aota S, Parsons R, Yamada KM. Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. Science. 1998;280:614-7.
    • (1998) Science , vol.280 , pp. 614-617
    • Tamura, M.1    Gu, J.2    Matsumoto, K.3    Aota, S.4    Parsons, R.5    Yamada, K.M.6
  • 53
    • 36949034117 scopus 로고    scopus 로고
    • Mechanisms of disease: the PI3K-Akt-PTEN signaling node - an intercept point for the control of angiogenesis in brain tumors
    • Castellino RC, Durden DL. Mechanisms of disease: the PI3K-Akt-PTEN signaling node - an intercept point for the control of angiogenesis in brain tumors. Nat Clin Pract Neurol. 2007;3:682-93.
    • (2007) Nat Clin Pract Neurol , vol.3 , pp. 682-693
    • Castellino, R.C.1    Durden, D.L.2
  • 54
    • 75949106927 scopus 로고    scopus 로고
    • Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status
    • Zhou X, Ren Y, Moore L, Mei M, You Y, Xu P, et al. Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status. Lab Investig. 2010;90:144-55.
    • (2010) Lab Investig , vol.90 , pp. 144-155
    • Zhou, X.1    Ren, Y.2    Moore, L.3    Mei, M.4    You, Y.5    Xu, P.6
  • 55
    • 84922276461 scopus 로고    scopus 로고
    • Deregulation of microRNAs Let-7a and miR-21 mediate aberrant STAT3 signaling during human papillomavirus-induced cervical carcinogenesis: role of E6 oncoprotein
    • Shishodia G, Verma G, Srivastava Y, Mehrotra R, Das BC, Bharti AC. Deregulation of microRNAs Let-7a and miR-21 mediate aberrant STAT3 signaling during human papillomavirus-induced cervical carcinogenesis: role of E6 oncoprotein. BMC Cancer. 2014;14:996.
    • (2014) BMC Cancer , vol.14 , pp. 996
    • Shishodia, G.1    Verma, G.2    Srivastava, Y.3    Mehrotra, R.4    Das, B.C.5    Bharti, A.C.6
  • 57
    • 84896703100 scopus 로고    scopus 로고
    • Construction and analysis of regulatory genetic networks in cervical cancer based on involved microRNAs, target genes, transcription factors and host genes
    • Wang N, Xu Z, Wang K, Zhu M, Li Y. Construction and analysis of regulatory genetic networks in cervical cancer based on involved microRNAs, target genes, transcription factors and host genes. Oncol Lett. 2014;7(4):1279-83.
    • (2014) Oncol Lett , vol.7 , Issue.4 , pp. 1279-1283
    • Wang, N.1    Xu, Z.2    Wang, K.3    Zhu, M.4    Li, Y.5
  • 59
    • 34250851115 scopus 로고    scopus 로고
    • A microRNA component of the p53 tumour suppressor network
    • He L, He X, Lim LP, de Stanchina E, Xuan Z, Liang Y, et al. A microRNA component of the p53 tumour suppressor network. Nature. 2007;447:1130-4.
    • (2007) Nature , vol.447 , pp. 1130-1134
    • He, L.1    He, X.2    Lim, L.P.3    Stanchina, E.4    Xuan, Z.5    Liang, Y.6
  • 62
    • 38149042783 scopus 로고    scopus 로고
    • Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells
    • Frankel LB, Christoffersen NR, Jacobsen A, Lindow M, Krogh A, Lund AH. Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J Biol Chem. 2008;283:1026-33.
    • (2008) J Biol Chem , vol.283 , pp. 1026-1033
    • Frankel, L.B.1    Christoffersen, N.R.2    Jacobsen, A.3    Lindow, M.4    Krogh, A.5    Lund, A.H.6
  • 64
    • 84928889340 scopus 로고    scopus 로고
    • Overexpression of miR-21 promotes the proliferation and migration of cervical cancer cells via the inhibition of PTEN
    • Xu J, Zhang W, Lv Q, Zhu D. Overexpression of miR-21 promotes the proliferation and migration of cervical cancer cells via the inhibition of PTEN. Oncol Rep. 2015;33(6):3108-16.
    • (2015) Oncol Rep , vol.33 , Issue.6 , pp. 3108-3116
    • Xu, J.1    Zhang, W.2    Lv, Q.3    Zhu, D.4
  • 65
    • 0031001041 scopus 로고    scopus 로고
    • TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta
    • Li DM, Sun H. TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta. Cancer Res. 1997;57:2124-9.
    • (1997) Cancer Res , vol.57 , pp. 2124-2129
    • Li, D.M.1    Sun, H.2
  • 66
    • 38449116969 scopus 로고    scopus 로고
    • Caspase-independent autophagic cytotoxicity in etoposide-treated CaSki cervical carcinoma cells
    • Lee SB, Tong SY, Kim JJ, Um SJ, Park JS. Caspase-independent autophagic cytotoxicity in etoposide-treated CaSki cervical carcinoma cells. DNA Cell Biol. 2007;26(10):713-20.
    • (2007) DNA Cell Biol , vol.26 , Issue.10 , pp. 713-720
    • Lee, S.B.1    Tong, S.Y.2    Kim, J.J.3    Um, S.J.4    Park, J.S.5
  • 67
    • 44949102384 scopus 로고    scopus 로고
    • Autophagy is associated with apoptosis in cisplatin injury to renal tubular epithelial cells
    • Yang C, Kaushal V, Shah SV, Kaushal GP. Autophagy is associated with apoptosis in cisplatin injury to renal tubular epithelial cells. Am J Physiol Renal Physiol. 2008;294(4):F777-87.
    • (2008) Am J Physiol Renal Physiol , vol.294 , Issue.4 , pp. F777-F787
    • Yang, C.1    Kaushal, V.2    Shah, S.V.3    Kaushal, G.P.4
  • 68
    • 34548862577 scopus 로고    scopus 로고
    • MicroRNAs in tumorigenesis: a primer
    • Zhang W, Dahlberg JE, Tam W. MicroRNAs in tumorigenesis: a primer. Am J Pathol. 2007;171:728-38.
    • (2007) Am J Pathol , vol.171 , pp. 728-738
    • Zhang, W.1    Dahlberg, J.E.2    Tam, W.3
  • 69
    • 46749090394 scopus 로고    scopus 로고
    • MicroRNA: an emerging therapeutic target and intervention tool
    • Liu Z, Sall A, Yang D. MicroRNA: an emerging therapeutic target and intervention tool. Int J Mol Sci. 2008;9:978-99.
    • (2008) Int J Mol Sci , vol.9 , pp. 978-999
    • Liu, Z.1    Sall, A.2    Yang, D.3
  • 70
    • 34250317284 scopus 로고    scopus 로고
    • MicroRNA: Potential for cancer detection, diagnosis, and prognosis
    • Tricoli JV, Jacobson JW. MicroRNA: Potential for cancer detection, diagnosis, and prognosis. Cancer Res. 2007;67:4553-5.
    • (2007) Cancer Res , vol.67 , pp. 4553-4555
    • Tricoli, J.V.1    Jacobson, J.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.