Alterations in microRNAs miR-21 and let-7a correlate with aberrant STAT3 signaling and downstream effects during cervical carcinogenesis

Molecular Cancer

Volumn 14, Issue 1, 2015, Pages

  Shishodia, Gauri ^a,c,d   Shukla, Shirish ^a,e   Srivastava, Yogesh ^a   Masaldan, Shashank ^a   Mehta, Sumita ^b   Bhambhani, Suresh ^a   Sharma, Shashi ^a   Mehrotra, Ravi ^a   Das, Bhudev Chandra ^c   Bharti, Alok Chandra ^a  

^a INSTITUTE OF CYTOLOGY AND PREVENTIVE ONCOLOGY   (India)

^b UNIVERSITY COLLEGE OF MEDICAL SCIENCES   (India)

^c UNIVERSITY OF DELHI   (India)

^d LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^e UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Cervical cancer; HPV; HSIL; Let 7a; LSIL; MiR 21; MMPs; PSTAT3; PTEN; STAT3; TIMP 3

Indexed keywords

GELATINASE A; GELATINASE B; MICRORNA; MICRORNA 121; MICRORNA 21; MICRORNA LET 7A; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; STAT3 PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE 3; UNCLASSIFIED DRUG; E6 PROTEIN, HUMAN PAPILLOMAVIRUS TYPE 16; MESSENGER RNA; MIRN21 MICRORNA, HUMAN; MIRNLET7 MICRORNA, HUMAN; ONCOPROTEIN; REPRESSOR PROTEIN;

ARTICLE; CANCER GRADING; CARCINOGENESIS; CELL DIFFERENTIATION; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOLOGY; DENSITOMETRY; DNA ISOLATION; FEMALE; GENOTYPE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; KRUSKAL WALLIS TEST; MALIGNANT TRANSFORMATION; MOLECULAR DYNAMICS; PAPILLOMAVIRUS INFECTION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; SIGNAL TRANSDUCTION; UTERINE CERVIX CANCER; BIOLOGICAL MODEL; BIOPSY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; HUMAN PAPILLOMAVIRUS TYPE 16; METABOLISM; PATHOLOGY; PHOSPHORYLATION; TUMOR CELL LINE; UTERINE CERVIX; UTERINE CERVIX TUMOR;

BIOPSY; CARCINOGENESIS; CELL LINE, TUMOR; CERVIX UTERI; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMAN PAPILLOMAVIRUS 16; HUMANS; MICRORNAS; MODELS, BIOLOGICAL; ONCOGENE PROTEINS, VIRAL; PHOSPHORYLATION; REPRESSOR PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; UTERINE CERVICAL NEOPLASMS;

EID: 84931049122     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/s12943-015-0385-2     Document Type: Article

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