Gold nanoparticle-DNA aptamer conjugate-assisted delivery of antimicrobial peptide effectively eliminates intracellular Salmonella enterica serovar Typhimurium

Biomaterials

Volumn 104, Issue , 2016, Pages 43-51

  Yeom, Ji Hyun ^a   Lee, Boeun ^a   Kim, Daeyoung ^a   Lee, Jong kook ^b   Kim, Suk ^c   Bae, Jeehyeon ^a   Park, Yoonkyung ^b   Lee, Kangseok ^a  

^a Chung Ang University   (South Korea)

^b Chosun University   (South Korea)

^c Gyeongsang National University   (South Korea)

Author keywords

A3 APO; Antimicrobial peptides; Gold nanoparticle; S.Typhimurium

Indexed keywords

BACTERIA; CYTOLOGY; DNA; GOLD; MAMMALS; METAL NANOPARTICLES; MICROORGANISMS; NANOPARTICLES; PEPTIDES; POLYPEPTIDES;

A3-APO; ANTIBACTERIAL COMPOUNDS; ANTIMICROBIAL PEPTIDE; BACTERIAL INFECTIONS; GOLD NANOPARTICLES; INTRAVENOUS INJECTIONS; S.TYPHIMURIUM; SALMONELLA ENTERICA SEROVAR TYPHIMURIUM;

SALMONELLA;

APTAMER; GOLD NANOPARTICLE; HEXAHISTIDINE; LIPOSOME; POLYPEPTIDE ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE; GOLD; METAL NANOPARTICLE; NANOCAPSULE; NANOCONJUGATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL OUTER MEMBRANE; BACTERICIDAL ACTIVITY; CELL COUNT; CELL MEMBRANE; CELL PROLIFERATION; CELL VIABILITY; CIRCULAR DICHROISM; COLONY FORMING UNIT; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG BINDING; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG STABILITY; FEMALE; HELA CELL LINE; HOST CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR SPACE; LIVER; MAMMAL CELL; MEMBRANE DEPOLARIZATION; MESENTERY LYMPH NODE; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SALMONELLA ENTERICA SEROVAR TYPHIMURIUM; SCANNING ELECTRON MICROSCOPY; SPLEEN; TYPHOID FEVER; WESTERN BLOTTING; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; PARTICLE SIZE; PHYSIOLOGY; SALMONELLA ENTERICA SEROVAR TYPHI; TREATMENT OUTCOME; ULTRASTRUCTURE;

ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; APTAMERS, NUCLEOTIDE; CELL SURVIVAL; GOLD; HELA CELLS; HUMANS; METAL NANOPARTICLES; NANOCAPSULES; NANOCONJUGATES; PARTICLE SIZE; SALMONELLA TYPHI; TREATMENT OUTCOME;

EID: 84978871085     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2016.07.009     Document Type: Article

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