-
1
-
-
84919871373
-
Screening and prostate cancer mortality: results of the European Randomised Study of Screening for Prostate Cancer (ERSPC) at 13 years of follow-up
-
Schroder FH, Hugosson J, Roobol MJ et al. Screening and prostate cancer mortality: results of the European Randomised Study of Screening for Prostate Cancer (ERSPC) at 13 years of follow-up. Lancet 2014; 384: 2027–35.
-
(2014)
Lancet
, vol.384
, pp. 2027-2035
-
-
Schroder, F.H.1
Hugosson, J.2
Roobol, M.J.3
-
2
-
-
63249122661
-
Mortality results from a randomized prostate-cancer screening trial
-
Andriole GL, Crawford ED, Grubb RL 3rd et al. Mortality results from a randomized prostate-cancer screening trial. N Engl J Med 2009; 360: 1310–9.
-
(2009)
N Engl J Med
, vol.360
, pp. 1310-1319
-
-
Andriole, G.L.1
Crawford, E.D.2
Grubb, R.L.3
-
3
-
-
84868592725
-
Chemoprevention of prostate cancer: soy isoflavones and curcumin
-
Horie S. Chemoprevention of prostate cancer: soy isoflavones and curcumin. Korean J Urol 2012; 53: 665–72.
-
(2012)
Korean J Urol
, vol.53
, pp. 665-672
-
-
Horie, S.1
-
4
-
-
84892162689
-
Soy isoflavones and prostate cancer: a review of molecular mechanisms
-
Mahmoud AM, Yang W, Bosland MC. Soy isoflavones and prostate cancer: a review of molecular mechanisms. J Steroid Biochem Mol Biol 2014; 140: 116–32.
-
(2014)
J Steroid Biochem Mol Biol
, vol.140
, pp. 116-132
-
-
Mahmoud, A.M.1
Yang, W.2
Bosland, M.C.3
-
5
-
-
38849089378
-
Effects of soy protein isolate consumption on prostate cancer biomarkers in men with HGPIN, ASAP, and low-grade prostate cancer
-
Hamilton-Reeves JM, Rebello SA, Thomas W, Kurzer MS, Slaton JW. Effects of soy protein isolate consumption on prostate cancer biomarkers in men with HGPIN, ASAP, and low-grade prostate cancer. Nutr Cancer 2008; 60: 7–13.
-
(2008)
Nutr Cancer
, vol.60
, pp. 7-13
-
-
Hamilton-Reeves, J.M.1
Rebello, S.A.2
Thomas, W.3
Kurzer, M.S.4
Slaton, J.W.5
-
6
-
-
34447132197
-
Isoflavone-rich soy protein isolate suppresses androgen receptor expression without altering estrogen receptor-beta expression or serum hormonal profiles in men at high risk of prostate cancer
-
Hamilton-Reeves JM, Rebello SA, Thomas W, Slaton JW, Kurzer MS. Isoflavone-rich soy protein isolate suppresses androgen receptor expression without altering estrogen receptor-beta expression or serum hormonal profiles in men at high risk of prostate cancer. J Nutr 2007; 137: 1769–75.
-
(2007)
J Nutr
, vol.137
, pp. 1769-1775
-
-
Hamilton-Reeves, J.M.1
Rebello, S.A.2
Thomas, W.3
Slaton, J.W.4
Kurzer, M.S.5
-
7
-
-
34948885745
-
Soy protein isolate increases urinary estrogens and the ratio of 2:16alpha-hydroxyestrone in men at high risk of prostate cancer
-
Hamilton-Reeves JM, Rebello SA, Thomas W, Slaton JW, Kurzer MS. Soy protein isolate increases urinary estrogens and the ratio of 2:16alpha-hydroxyestrone in men at high risk of prostate cancer. J Nutr 2007; 137: 2258–63.
-
(2007)
J Nutr
, vol.137
, pp. 2258-2263
-
-
Hamilton-Reeves, J.M.1
Rebello, S.A.2
Thomas, W.3
Slaton, J.W.4
Kurzer, M.S.5
-
8
-
-
84855481687
-
Prostate cancer chemoprevention study: an investigative randomized control study using purified isoflavones in men with rising prostate-specific antigen
-
Miyanaga N, Akaza H, Hinotsu S et al. Prostate cancer chemoprevention study: an investigative randomized control study using purified isoflavones in men with rising prostate-specific antigen. Cancer Sci 2012; 103: 125–30.
-
(2012)
Cancer Sci
, vol.103
, pp. 125-130
-
-
Miyanaga, N.1
Akaza, H.2
Hinotsu, S.3
-
9
-
-
84902332134
-
Soy and soy isoflavones in prostate cancer: a systematic review and meta-analysis of randomized controlled trials
-
van Die MD, Bone KM, Williams SG, Pirotta MV. Soy and soy isoflavones in prostate cancer: a systematic review and meta-analysis of randomized controlled trials. BJU Int 2014; 113: E119–30.
-
(2014)
BJU Int
, vol.113
, pp. E119-E130
-
-
van Die, M.D.1
Bone, K.M.2
Williams, S.G.3
Pirotta, M.V.4
-
10
-
-
78249240074
-
Effects of a high dose, aglycone-rich soy extract on prostate-specific antigen and serum isoflavone concentrations in men with localized prostate cancer
-
deVere White RW, Tsodikov A, Stapp EC, Soares SE, Fujii H, Hackman RM. Effects of a high dose, aglycone-rich soy extract on prostate-specific antigen and serum isoflavone concentrations in men with localized prostate cancer. Nutr Cancer 2010; 62: 1036–43.
-
(2010)
Nutr Cancer
, vol.62
, pp. 1036-1043
-
-
deVere White, R.W.1
Tsodikov, A.2
Stapp, E.C.3
Soares, S.E.4
Fujii, H.5
Hackman, R.M.6
-
11
-
-
77249154595
-
Results of a randomized phase I dose-finding trial of several doses of isoflavones in men with localized prostate cancer: administration prior to radical prostatectomy
-
Kumar NB, Kang L, Pow-Sang J et al. Results of a randomized phase I dose-finding trial of several doses of isoflavones in men with localized prostate cancer: administration prior to radical prostatectomy. J Soc Integr Oncol 2010; 8: 3–13.
-
(2010)
J Soc Integr Oncol
, vol.8
, pp. 3-13
-
-
Kumar, N.B.1
Kang, L.2
Pow-Sang, J.3
-
12
-
-
36849067027
-
A Phase II randomized, placebo-controlled clinical trial of purified isoflavones in modulating steroid hormones in men diagnosed with localized prostate cancer
-
Kumar NB, Krischer JP, Allen K et al. A Phase II randomized, placebo-controlled clinical trial of purified isoflavones in modulating steroid hormones in men diagnosed with localized prostate cancer. Nutr Cancer 2007; 59: 163–8.
-
(2007)
Nutr Cancer
, vol.59
, pp. 163-168
-
-
Kumar, N.B.1
Krischer, J.P.2
Allen, K.3
-
13
-
-
80051721130
-
Efficacy and safety of short-term genistein intervention in patients with localized prostate cancer prior to radical prostatectomy: a randomized, placebo-controlled, double-blind Phase 2 clinical trial
-
Lazarevic B, Boezelijn G, Diep LM et al. Efficacy and safety of short-term genistein intervention in patients with localized prostate cancer prior to radical prostatectomy: a randomized, placebo-controlled, double-blind Phase 2 clinical trial. Nutr Cancer 2011; 63: 889–98.
-
(2011)
Nutr Cancer
, vol.63
, pp. 889-898
-
-
Lazarevic, B.1
Boezelijn, G.2
Diep, L.M.3
-
14
-
-
0036270108
-
Expression of prostate-specific antigen is transcriptionally regulated by genistein in prostate cancer cells
-
Davis JN, Kucuk O, Sarkar FH. Expression of prostate-specific antigen is transcriptionally regulated by genistein in prostate cancer cells. Mol Carcinog 2002; 34: 91–101.
-
(2002)
Mol Carcinog
, vol.34
, pp. 91-101
-
-
Davis, J.N.1
Kucuk, O.2
Sarkar, F.H.3
-
15
-
-
55749097776
-
Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function
-
Basak S, Pookot D, Noonan EJ, Dahiya R. Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function. Mol Cancer Ther 2008; 7: 3195–202.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 3195-3202
-
-
Basak, S.1
Pookot, D.2
Noonan, E.J.3
Dahiya, R.4
-
16
-
-
74449089780
-
Castration resistance of prostate cancer cells caused by castration-induced oxidative stress through Twist1 and androgen receptor overexpression
-
Shiota M, Yokomizo A, Tada Y et al. Castration resistance of prostate cancer cells caused by castration-induced oxidative stress through Twist1 and androgen receptor overexpression. Oncogene 2010; 29: 237–50.
-
(2010)
Oncogene
, vol.29
, pp. 237-250
-
-
Shiota, M.1
Yokomizo, A.2
Tada, Y.3
-
17
-
-
84883472793
-
Mutual regulation between Raf/MEK/ERK signaling and Y-box-binding protein-1 promotes prostate cancer progression
-
Imada K, Shiota M, Kohashi K et al. Mutual regulation between Raf/MEK/ERK signaling and Y-box-binding protein-1 promotes prostate cancer progression. Clin Cancer Res 2013; 19: 4638–50.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 4638-4650
-
-
Imada, K.1
Shiota, M.2
Kohashi, K.3
-
18
-
-
84903594617
-
PMA induces androgen receptor downregulation and cellular apoptosis in prostate cancer cells
-
Itsumi M, Shiota M, Yokomizo A et al. PMA induces androgen receptor downregulation and cellular apoptosis in prostate cancer cells. J Mol Endocrinol 2014; 53: 31–41.
-
(2014)
J Mol Endocrinol
, vol.53
, pp. 31-41
-
-
Itsumi, M.1
Shiota, M.2
Yokomizo, A.3
-
19
-
-
84896712232
-
Inhibition of protein kinase C/Twist1 signaling augments anticancer effects of androgen deprivation and enzalutamide in prostate cancer
-
Shiota M, Yokomizo A, Takeuchi A et al. Inhibition of protein kinase C/Twist1 signaling augments anticancer effects of androgen deprivation and enzalutamide in prostate cancer. Clin Cancer Res 2014; 20: 951–61.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 951-961
-
-
Shiota, M.1
Yokomizo, A.2
Takeuchi, A.3
-
20
-
-
78751496139
-
Statins reduce the androgen sensitivity and cell proliferation by decreasing the androgen receptor protein in prostate cancer cells
-
Yokomizo A, Shiota M, Kashiwagi E et al. Statins reduce the androgen sensitivity and cell proliferation by decreasing the androgen receptor protein in prostate cancer cells. Prostate 2011; 71: 298–304.
-
(2011)
Prostate
, vol.71
, pp. 298-304
-
-
Yokomizo, A.1
Shiota, M.2
Kashiwagi, E.3
-
21
-
-
84861691516
-
Androgen deprivation causes truncation of the C-terminal region of androgen receptor in human prostate cancer LNCaP cells
-
Harada N, Inoue K, Yamaji R, Nakano Y, Inui H. Androgen deprivation causes truncation of the C-terminal region of androgen receptor in human prostate cancer LNCaP cells. Cancer Sci 2012; 103: 1022–7.
-
(2012)
Cancer Sci
, vol.103
, pp. 1022-1027
-
-
Harada, N.1
Inoue, K.2
Yamaji, R.3
Nakano, Y.4
Inui, H.5
-
22
-
-
84895924580
-
Skp2 regulates androgen receptor through ubiquitin-mediated degradation independent of Akt/mTOR pathways in prostate cancer
-
Li B, Lu W, Yang Q, Yu X, Matusik RJ, Chen Z. Skp2 regulates androgen receptor through ubiquitin-mediated degradation independent of Akt/mTOR pathways in prostate cancer. Prostate 2014; 74: 421–32.
-
(2014)
Prostate
, vol.74
, pp. 421-432
-
-
Li, B.1
Lu, W.2
Yang, Q.3
Yu, X.4
Matusik, R.J.5
Chen, Z.6
-
23
-
-
0033174070
-
p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells
-
Sutterluty H, Chatelain E, Marti A et al. p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells. Nat Cell Biol 1999; 1: 207–14.
-
(1999)
Nat Cell Biol
, vol.1
, pp. 207-214
-
-
Sutterluty, H.1
Chatelain, E.2
Marti, A.3
-
24
-
-
77953751445
-
Equol: history, chemistry, and formation
-
Setchell KD, Clerici C. Equol: history, chemistry, and formation. J Nutr 2010; 140: 1355S–62S.
-
(2010)
J Nutr
, vol.140
, pp. 62S-1355S
-
-
Setchell, K.D.1
Clerici, C.2
-
25
-
-
77953740445
-
Equol: pharmacokinetics and biological actions
-
Setchell KD, Clerici C. Equol: pharmacokinetics and biological actions. J Nutr 2010; 140: 1363S–8S.
-
(2010)
J Nutr
, vol.140
, pp. 8S-1363S
-
-
Setchell, K.D.1
Clerici, C.2
-
26
-
-
84861686421
-
Prostate cancer chemoprevention by soy isoflavones: role of intestinal bacteria as the “second human genome
-
Akaza H. Prostate cancer chemoprevention by soy isoflavones: role of intestinal bacteria as the “second human genome”. Cancer Sci 2012; 103: 969–75.
-
(2012)
Cancer Sci
, vol.103
, pp. 969-975
-
-
Akaza, H.1
-
27
-
-
22844432021
-
Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors
-
Bali P, Pranpat M, Bradner J et al. Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors. J Biol Chem 2005; 280: 26729–34.
-
(2005)
J Biol Chem
, vol.280
, pp. 26729-26734
-
-
Bali, P.1
Pranpat, M.2
Bradner, J.3
-
28
-
-
55549148757
-
Regulation of Akt/FOXO3a/GSK-3beta/AR signaling network by isoflavone in prostate cancer cells
-
Li Y, Wang Z, Kong D, Li R, Sarkar SH, Sarkar FH. Regulation of Akt/FOXO3a/GSK-3beta/AR signaling network by isoflavone in prostate cancer cells. J Biol Chem 2008; 283: 27707–16.
-
(2008)
J Biol Chem
, vol.283
, pp. 27707-27716
-
-
Li, Y.1
Wang, Z.2
Kong, D.3
Li, R.4
Sarkar, S.H.5
Sarkar, F.H.6
-
29
-
-
0036683093
-
Phosphorylation-dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase
-
Lin HK, Wang L, Hu YC, Altuwaijri S, Chang C. Phosphorylation-dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase. EMBO J 2002; 21: 4037–48.
-
(2002)
EMBO J
, vol.21
, pp. 4037-4048
-
-
Lin, H.K.1
Wang, L.2
Hu, Y.C.3
Altuwaijri, S.4
Chang, C.5
-
30
-
-
63249104202
-
Regulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitination
-
Xu K, Shimelis H, Linn DE et al. Regulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitination. Cancer Cell 2009; 15: 270–82.
-
(2009)
Cancer Cell
, vol.15
, pp. 270-282
-
-
Xu, K.1
Shimelis, H.2
Linn, D.E.3
-
31
-
-
84876441841
-
The E3 ubiquitin ligase Siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity
-
Qi J, Tripathi M, Mishra R et al. The E3 ubiquitin ligase Siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity. Cancer Cell 2013; 23: 332–46.
-
(2013)
Cancer Cell
, vol.23
, pp. 332-346
-
-
Qi, J.1
Tripathi, M.2
Mishra, R.3
-
32
-
-
24944458421
-
Genistein, a dietary isoflavone, down-regulates the MDM2 oncogene at both transcriptional and posttranslational levels
-
Li M, Zhang Z, Hill DL, Chen X, Wang H, Zhang R. Genistein, a dietary isoflavone, down-regulates the MDM2 oncogene at both transcriptional and posttranslational levels. Cancer Res 2005; 65: 8200–8.
-
(2005)
Cancer Res
, vol.65
, pp. 8200-8208
-
-
Li, M.1
Zhang, Z.2
Hill, D.L.3
Chen, X.4
Wang, H.5
Zhang, R.6
-
33
-
-
84886081867
-
Differential effects of genistein on prostate cancer cells depend on mutational status of the androgen receptor
-
Mahmoud AM, Zhu T, Parray A et al. Differential effects of genistein on prostate cancer cells depend on mutational status of the androgen receptor. PLoS ONE 2013; 8: e78479.
-
(2013)
PLoS ONE
, vol.8
-
-
Mahmoud, A.M.1
Zhu, T.2
Parray, A.3
-
34
-
-
0037081891
-
Dietary genistein down-regulates androgen and estrogen receptor expression in the rat prostate
-
Fritz WA, Wang J, Eltoum IE, Lamartiniere CA. Dietary genistein down-regulates androgen and estrogen receptor expression in the rat prostate. Mol Cell Endocrinol 2002; 186: 89–99.
-
(2002)
Mol Cell Endocrinol
, vol.186
, pp. 89-99
-
-
Fritz, W.A.1
Wang, J.2
Eltoum, I.E.3
Lamartiniere, C.A.4
-
35
-
-
84928818101
-
Genistein increases estrogen receptor beta expression in prostate cancer via reducing its promoter methylation
-
Mahmoud AM, Al-Alem U, Ali MM, Bosland MC. Genistein increases estrogen receptor beta expression in prostate cancer via reducing its promoter methylation. J Steroid Biochem Mol Biol 2015; 152: 62–75.
-
(2015)
J Steroid Biochem Mol Biol
, vol.152
, pp. 62-75
-
-
Mahmoud, A.M.1
Al-Alem, U.2
Ali, M.M.3
Bosland, M.C.4
-
36
-
-
33947626040
-
Genistein chemoprevention of prostate cancer in TRAMP mice
-
Wang J, Eltoum IE, Lamartiniere CA. Genistein chemoprevention of prostate cancer in TRAMP mice. J Carcinog 2007; 6: 3.
-
(2007)
J Carcinog
, vol.6
, pp. 3
-
-
Wang, J.1
Eltoum, I.E.2
Lamartiniere, C.A.3
-
37
-
-
0025644325
-
A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens
-
Veldscholte J, Ris-Stalpers C, Kuiper GG et al. A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens. Biochem Biophys Res Commun 1990; 173: 534–40.
-
(1990)
Biochem Biophys Res Commun
, vol.173
, pp. 534-540
-
-
Veldscholte, J.1
Ris-Stalpers, C.2
Kuiper, G.G.3
-
38
-
-
0033176887
-
SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27
-
Carrano AC, Eytan E, Hershko A, Pagano M. SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27. Nat Cell Biol 1999; 1: 193–9.
-
(1999)
Nat Cell Biol
, vol.1
, pp. 193-199
-
-
Carrano, A.C.1
Eytan, E.2
Hershko, A.3
Pagano, M.4
-
39
-
-
44349122993
-
Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer
-
Frescas D, Pagano M. Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer. Nat Rev Cancer 2008; 8: 438–49.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 438-449
-
-
Frescas, D.1
Pagano, M.2
-
40
-
-
0035300409
-
Androgen receptor stabilization in recurrent prostate cancer is associated with hypersensitivity to low androgen
-
Gregory CW, Johnson RT Jr, Mohler JL, French FS, Wilson EM. Androgen receptor stabilization in recurrent prostate cancer is associated with hypersensitivity to low androgen. Cancer Res 2001; 61: 2892–8.
-
(2001)
Cancer Res
, vol.61
, pp. 2892-2898
-
-
Gregory, C.W.1
Johnson, R.T.2
Mohler, J.L.3
French, F.S.4
Wilson, E.M.5
-
41
-
-
80052270884
-
Oxidative stress and androgen receptor signaling in the development and progression of castration-resistant prostate cancer
-
Shiota M, Yokomizo A, Naito S. Oxidative stress and androgen receptor signaling in the development and progression of castration-resistant prostate cancer. Free Radic Biol Med 2011; 51: 1320–8.
-
(2011)
Free Radic Biol Med
, vol.51
, pp. 1320-1328
-
-
Shiota, M.1
Yokomizo, A.2
Naito, S.3
-
42
-
-
0036689920
-
Is daidzein non-metabolizer a high risk for prostate cancer? A case-controlled study of serum soybean isoflavone concentration
-
Akaza H, Miyanaga N, Takashima N et al. Is daidzein non-metabolizer a high risk for prostate cancer? A case-controlled study of serum soybean isoflavone concentration. Jpn J Clin Oncol 2002; 32: 296–300.
-
(2002)
Jpn J Clin Oncol
, vol.32
, pp. 296-300
-
-
Akaza, H.1
Miyanaga, N.2
Takashima, N.3
-
43
-
-
65449151910
-
Prostatic soy isoflavone concentrations exceed serum levels after dietary supplementation
-
Gardner CD, Oelrich B, Liu JP, Feldman D, Franke AA, Brooks JD. Prostatic soy isoflavone concentrations exceed serum levels after dietary supplementation. Prostate 2009; 69: 719–26.
-
(2009)
Prostate
, vol.69
, pp. 719-726
-
-
Gardner, C.D.1
Oelrich, B.2
Liu, J.P.3
Feldman, D.4
Franke, A.A.5
Brooks, J.D.6
|