Skp2 regulates androgen receptor through ubiquitin-mediated degradation independent of akt/mTOR pathways in prostate cancer

Prostate

Volumn 74, Issue 4, 2014, Pages 421-432

  Li, Bo ^a   Lu, Wenfu ^a   Yang, Qing ^a   Yu, Xiuping ^b   Matusik, Robert J ^b   Chen, Zhenbang ^a  

^a MEHARRY MEDICAL COLLEGE   (United States)

^b VANDERBILT UNIVERSITY   (United States)

Author keywords

Androgen receptor (AR); Prostate cancer (PCa); Skp2; Ubiquitination

Indexed keywords

ANDROGEN RECEPTOR; DACTOLISIB; MAMMALIAN TARGET OF RAPAMYCIN; MUTANT PROTEIN; PROSTATE SPECIFIC ANTIGEN; PROTEIN KINASE B; S PHASE KINASE ASSOCIATED PROTEIN 2; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; UBIQUITIN;

ARTICLE; BIOASSAY; CANCER CELL; CELL INVASION; CELL LEVEL; CELL PROLIFERATION; CONTROLLED STUDY; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; LUCIFERASE ASSAY; MALE; MUTAGENESIS; PLASMID; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE CANCER CELL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; UBIQUITINATION; UBIQUITINATION ASSAY; UPREGULATION; WESTERN BLOTTING;

ANDROGEN RECEPTOR (AR); PROSTATE CANCER (PCA); SKP2; UBIQUITINATION;

CELL LINE, TUMOR; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMIDAZOLES; MALE; PHOSPHORYLATION; PROSTATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-AKT; QUINOLINES; RECEPTORS, ANDROGEN; S-PHASE KINASE-ASSOCIATED PROTEINS; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; UBIQUITIN; UBIQUITINATION;

EID: 84895924580     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.22763     Document Type: Article

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