Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma

Nature

Volumn 535, Issue 7611, 2016, Pages 246-251

  Powers, John T ^a   Tsanov, Kaloyan M ^a   Pearson, Daniel S ^a   Roels, Frederik ^b   Spina, Catherine S ^c   Ebright, Richard ^a   Seligson, Marc ^a   De Soysa, Yvanka ^a   Cahan, Patrick ^a   Theißen, Jessica ^b   Tu, Ho Chou ^a   Han, Areum ^a   Kurek, Kyle C ^a   Lapier, Grace S ^a   Osborne, Jihan K ^a   Ross, Samantha J ^a   Cesana, Marcella ^a   Collins, James J ^c,d   Berthold, Frank ^b   Daley, George Q ^a,e,f  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^c HARVARD UNIVERSITY   (United States)

^d BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; HIGH MOBILITY GROUP A2 PROTEIN; LET 7 MICRORNA; LET 7A2 MICRORNA; LET 7F2 MICRORNA; LET 7G MICRORNA; LIN28B; MESSENGER RNA; MICRORNA; MICRORNA 100; MYC PROTEIN; NUCLEIC ACID SYNTHESIS INHIBITOR; RAS PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; LIN28B PROTEIN, HUMAN; MIRNLET7 MICRORNA, HUMAN; MYCN PROTEIN, HUMAN; N MYC PROTO ONCOGENE PROTEIN; NUCLEAR PROTEIN; ONCOPROTEIN; RNA BINDING PROTEIN;

CANCER; CELLS AND CELL COMPONENTS; CHROMOSOME; DISEASE INCIDENCE; GENE EXPRESSION; GENETIC ANALYSIS; RNA; TUMOR;

3' UNTRANSLATED REGION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENESIS; CELL PROLIFERATION; CHROMOSOME 3P; CHROMOSOME LOSS; CONTROLLED STUDY; FEMALE; GENE AMPLIFICATION; GENE DISRUPTION; GENE LOSS; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MOUSE; NEUROBLASTOMA; NEUROBLASTOMA CELL; NEUROBLASTOMA CELL LINE; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; BIOLOGICAL MODEL; CHROMOSOME DELETION; DRUG SCREENING; GENE DELETION; GENETICS; METABOLISM; PATHOLOGY; TUMOR GENE;

3' UNTRANSLATED REGIONS; ANIMALS; CHROMOSOME DELETION; FEMALE; GENE AMPLIFICATION; GENE DELETION; GENES, NEOPLASM; HUMANS; MICE; MICRORNAS; MODELS, GENETIC; N-MYC PROTO-ONCOGENE PROTEIN; NEUROBLASTOMA; NUCLEAR PROTEINS; ONCOGENE PROTEINS; RNA-BINDING PROTEINS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84978664408     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature18632     Document Type: Article

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