LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression

Nature Genetics

Volumn 44, Issue 11, 2012, Pages 1199-1206

  Molenaar, Jan J ^a   Domingo Fernández, Raquel ^b,c   Ebus, Marli E ^a   Lindner, Sven ^d   Koster, Jan ^a   Drabek, Ksenija ^a   Mestdagh, Pieter ^e   Van Sluis, Peter ^a   Valentijn, Linda J ^a   Van Nes, Johan ^a   Broekmans, Marloes ^a   Haneveld, Franciska ^a   Volckmann, Richard ^a   Bray, Isabella ^b,c   Heukamp, Lukas ^f   Sprüssel, Annika ^d   Thor, Theresa ^d   Kieckbusch, Kristina ^d   Klein Hitpass, Ludger ^d   Fischer, Matthias ^g   Vandesompele, Jo ^e   Schramm, Alexander ^d   Van Noesel, Max M ^h   Varesio, Luigi ⁱ   Speleman, Frank ^e   Eggert, Angelika ^d   Stallings, Raymond L ^b,c   Caron, Huib N ^a   Versteeg, Rogier ^a   Schulte, Johannes H ^d   more..

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^c NATIONAL CHILDREN S RESEARCH CENTRE   (Ireland)

^d UNIVERSITY HOSPITAL ESSEN   (Germany)

^e GHENT UNIVERSITY HOSPITAL   (Belgium)

^f UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^g UNIVERSITY OF COLOGNE   (Germany)

^h SOPHIA CHILDREN S HOSPITAL   (Netherlands)

ⁱ G GASLINI INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

LET 7 PROTEIN; LIN28B PROTEIN; MESSENGER RNA; MICRORNA; MYCN PROTEIN; PROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ABDOMINAL TUMOR; ADRENAL TUMOR; ADVERSE OUTCOME; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; CELIAC GANGLION; CELL FRACTIONATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; GENE OVEREXPRESSION; GENE REPRESSION; GENE SILENCING; HUMAN; HUMAN TISSUE; INTERNAL RIBOSOME ENTRY SITE; MOUSE; NERVE CELL DIFFERENTIATION; NEUROBLAST; NEUROBLASTOMA; NEUROBLASTOMA CELL; NONHUMAN; PRIMARY TUMOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUPERIOR CERVICAL GANGLION; TRANSGENIC MOUSE;

ANIMALS; CELL DIFFERENTIATION; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; MICE; MICE, TRANSGENIC; MICRORNAS; NEUROBLASTOMA; NUCLEAR PROTEINS; ONCOGENE PROTEINS; SIGNAL TRANSDUCTION;

EID: 84868210731     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.2436     Document Type: Article

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