RNA-ligase-dependent biases in miRNA representation in deep-sequenced small RNA cDNA libraries

RNA

Volumn 17, Issue 9, 2011, Pages 1697-1712

  Hafner, Markus ^a   Renwick, Neil ^a   Brown, Miguel ^a   Mihailović, Aleksandra ^a   Holoch, Daniel ^a   Lin, Caroa ^a   Pena, John T G ^a,b   Nusbaum, Jeffrey D ^a   Morozov, Pavel ^a   Ludwig, Janos ^a   Ojo, Tolulope ^a   Luo, Shujun ^c   Schroth, Gary ^c   Tuschl, Thomas ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c ILLUMINA INC   (United States)

Author keywords

Adapter ligation; High throughput sequencing; Next generation sequencing; Oligonucleotide linker ligation; Sequence specific bias; Small RNAs

Indexed keywords

COMPLEMENTARY DNA; MICRORNA; OLIGORIBONUCLEOTIDE; RNA; RNA LIGASE; RNL1 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DNA BARCODING; DNA LIBRARY; GENE FREQUENCY; GENE MUTATION; GENETIC VARIABILITY; HUMAN; LIGATION; MULTIPLEX POLYMERASE CHAIN REACTION; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; RAT; REVERSE TRANSCRIPTION; RNA SEQUENCE;

DNA PRIMERS; GENE EXPRESSION PROFILING; GENE LIBRARY; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; MICRORNAS; MULTIGENE FAMILY; OLIGONUCLEOTIDES; POLYMERASE CHAIN REACTION; RNA LIGASE (ATP); SEQUENCE ANALYSIS, RNA;

EID: 84860389888     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.2799511     Document Type: Article

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