Theory and practice of the orbitrap mass analyzer

Practical Aspects of Trapped Ion Mass Spectrometry: Volume IV: Theory and Instrumentation

Volumn , Issue , 2010, Pages 251-272

  Makarov, Alexander ^a  

^a THERMO FISHER SCIENTIFIC   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COMMERCIAL IMPLEMENTATION; MASS ANALYZERS; MULTIPLE REFLECTIONS; ORBITRAP; THEORY AND PRACTICE;

ELECTROSTATIC DEVICES;

EID: 84978619331     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1201/9781420083729     Document Type: Chapter

References (63)

1. Makarov, A. Electrostatic axially harmonic orbital trapping: a high-performance technique of mass analysis. Anal. Chem. 2000, 72, 1156-1162.
2. Earnshaw, S. On the nature of the molecular forces which regulate the constitution of the luminiferous ether. Trans. Camb. Phil. Soc. 1842, 7, 97-112.
3. Melzner, F. Pulsed time of flight mass spectrometers. U.S. Patent 1965, 3,226,543.
4. Benner, W.H. A gated electrostatic ion trap to repetitiously measure the charge and m/z of large electrospray ions. Anal.Chem. 1997, 69, 4152-4168.
5. May, M.A.; Marshall, A.G.; Wollnik, H. Spectral analysis based on bipolar time-domain sampling: a multiplex method for time-of-flight mass spectrometry. Anal.Chem. 1992, 64, 1601-1605.
6. Behrisch, R.; Blauth, E.W.; Melzner, F.; Meyer, E.H. Mass spectrometer. U.S. Patent 1965, 3,174,034.
7. Makarov, A.A.; Giannakopulos, A. Method of operating a multi-reflection ion trap. Patent 2008, WO2008059246.
8. Wollnik, H.; Przewloka, A. Time-of-flight mass spectrometers with multiply reflected ion trajectories. Int. J. Mass Spectrom. 1990, 96, 267-274.
9. Dahan, M.; Fishman, R.; Heber, O.;Rappaport, M.; Altstein, N.; Zajfman, D.; van der Zande, W.J. A new type of electrostatic ion trap for storage of fast ion beams. Rev. Sci. Instrum. 1998, 69, 76-83.
10. Su, C-S. Multiple reflection type time-of-flight mass spectrometer with two sets of parallel-plate electrostatic fields. Int. J. Mass Spectrom. 1989, 88, 21-28.
11. Nazarenko, L.M.; Sekunova, L.M.; Yakushev, E.M. Time-of-flight mass spectrometer with multiple reflections. Russian Patent, SU 1992, 1,725,289.
12. Verentchikov, A.N.; Yavor, M.I.; Hasin, Y.I.; Gavrik, M.A. Multi-reflection planar timeof-flight mass analyzer, Parts I and II. Tech. Phys. 2005, 50, 73-86.
13. Moller, S.P. ELISA, an electrostatic storage ring for atomic physics. Nucl. Instrum. Methods in Phys. Research Section A, 1997, 394, 281-286.
14. Oksman, P. A Fourier transform time-of-flight mass spectrometer. A SIMION approach. Int. J. Mass Spectrom. 1995, 141, 67-76.
15. Yamaguchi, S.; Ishihara, M.; Toyoda, M.; Okumura, D. Time-of-flight mass spectrometer. US Patent 2006, 7,148,473.
16. Matsuo, T.; Toyoda, M.; Sakurai, T.; Ishihara, M. Ion optics for multi-turn time-offlight mass spectrometers with variable mass resolution. J. Mass Spectrom. 1997, 32, 1179-1185.
17. Okumura, D.; Toyoda, M.; Ishihara, M.; Katakuse, I. A compact sector-type multiturn time-of-flight mass spectrometer MULTUM II. Nucl. Instrum. Methods in Phys. Research Section A 2004, 519, 331-337.
18. Sakurai, T.; Ito, H.; Matsuo, T. MS/MS and MS/MS/MS analyses in a multisector timeof-flight mass spectrometer. Anal. Chem. 1994, 66, 2313-2317.
19. Satoh, T.; Tsuno, H.; Iwanaga, M.; Kammei, Y. The design and characteristic features of a new time-of-flight mass spectrometer with a spiral ion trajectory. J. Am. Soc. Mass Spectrom. 2005, 16, 1969-1975.
20. Knight, R.D. Storage of ions from laser-produced plasmas. Appl. Phys. Lett. 1981, 38, 221-222.
21. Yang, L.; Church, D.A.; Tu, S.; Jin, J. Measured lifetimes of selected metastable levels of Arq + ions (q = 2,3,9 and 10) stored in an electrostatic ion trap. Phys. Rev. A 1994, 50, 177-186.
22. Bakker, J.M.B. The Spiratron. In: Advances in Mass Spectrometry. Vol. 5, ed. A. Quayle, London: Institute of Petroleum, 1971, 278-280.
23. Alimpiev, S.S.; Makarov, A.A.; Mlynski, V.V.; Nikiforov, S.M.; Sartakov, B.G. Time-offlight mass spectrometer. Russian Patent, SU 1991, 1,716,922.
24. Marshall, A.G.; Verdun, F.R. Fourier Transforms in NMR, Optical, and Mass Spectrometry: A User’s Handbook. Elsevier: Amsterdam, 1990.
25. Brock, A.; Rodriguez, N.; Zare, R.N. Hadamard transform time-of-flight mass spectrometry. Anal. Chem. 1998, 70, 3735-3741.
26. Kingdon, K.H. A method for the neutralization of electron space charge by positive ionization at very low gas pressures. Phys. Rev. 1923, 21, 408-418.
27. Hardman, M.; Makarov, A.A. Interfacing the Orbitrap mass analyzer to an electrospray ion source. Anal. Chem. 2003, 75, 1699-1705.
28. Hu, Q.; Noll, R.J.; Li, H.; Makarov, A.; Hardman, M.; Cooks, R.G. The Orbitrap: a new mass spectrometer. J. Mass Spectrom. 2005, 40, 430-443.
29. Makarov, A.; Denisov, E.; Kholomeev, A.; Balschun, W.; Lange, O.; Horning, S.; Strupat, K. Performance evaluation of a hybrid linear ion trap/orbitrap mass spectrometer. Anal. Chem. 2006, 78, 2113-2120.
30. Korsunskii, M.I.; Bazakutsa, V.A. A study of the ion-optical properties for a sectorshaped electrostatic field of the difference type. Soviet Physics-Tech. Phys. 1958, 3, 1396-1409.
31. Gall, L.N.; Golikov, Y.K.; Aleksandrov, M.L.; Pechalina, Y.E.; Holin, N.A. Time-offlight mass spectrometer. USSR Inventor’s Certificate 1986, 1,247,973.
32. Makarov, A.A. Mass spectrometer. US Patent 1999, 5,886,346.
33. Hu, Q.; Li, H.; Makarov, A.; Cooks, R.G.; Noll, R.J. Resonant AC dipolar excitation for ion motion control in the Orbitrap mass analyzer. J. Phys. Chem. A 2006, 110, 2682-2689.
34. Denisov, E.; Strupat, K.; Makarov, A.A.; Zabrouskov, V. Pushing intact protein detection limits of the Orbitrap mass analyzer. Proc. 55th ASMS Conference on Mass Spectrometry and Allied Topics, Indianapolis, June 3-7, 2007.
35. Masselon, C.; Tolmachev, A.V.; Anderson, G.A.; Harkewicz, R.; Smith, R.D. Mass measurement errors caused by “local” frequency perturbations in FTICR mass spectrometry. J. Am. Soc. Mass Spectrom. 2002, 13, 99-106.
36. Mitchell, D.W.; Smith, R.D. Cyclotron motion of two Coulombically interacting ion clouds with implications to Fourier-transform ion cyclotron resonance mass spectrometry. Phys. Rev. E 1995, 52, 4366-4386.
37. Pedersen, H.B.; Strasser, D.; Amarant, B.; Heber, O.; Rappaport, M.L.; Zajfman, D. Diffusion and synchronization in an ion-trap resonator. Phys. Rev. A 1992, 65, 042704.
38. Makarov, A.A.; Denisov, E.V.; Jung, G.; Balschun, W.; Horning, S. Improvements in an electrostatic trap. Patent 2006, WO2006129109.
39. Schwartz, J.C.; Senko, M.W.; Syka, J.E.P. A two-dimensional quadrupole ion trap mass spectrometer. J. Am. Soc. Mass Spectrom. 2002, 13, 659-669.
40. Olsen, J.V.; de Godoy, L.M.; Li, G.; Macek, B.; Mortensen, P.; Pesch, R.; Makarov, A.A., Lange, O., Horning, S., Mann, M. Parts per million mass accuracy on an orbitrap mass spectrometer via lock mass injection into a C-trap. Mol. Cell. Proteomics 2005, 4, 2010-2021.
41. Olsen, J.V.; Macek, B.; Lange, O.; Makarov, A.; Horning, S.; Mann, M. Higherenergy C-trap dissociation for peptide modification analysis. Nature Methods 2007, 4, 709-712.
42. Graumann, J.; Hubner, N.C.; Kim, J.B.; Ko, K.; Moser, M.; Kumar, C.; Cox, J.; Scholer, H.; Mann, M. Stable isotope labeling by amino acids in cell culture (SILAC) and proteome quantitation of mouse embryonic stem cells to a depth of 5,111 proteins. Mol. Cell. Proteomics 2008, 7, 672-683.
43. Hanke, S.; Besir, H.; Oesterhelt, D.; Mann, M. Absolute SILAC for accurate quantitation of proteins in complex mixtures down to the attomole Level. J. Proteome Research 2008, 7, 1118-1130.
44. Bantscheff, M.; Boesche, M.; Eberhard, D.; Matthieson, T.; Sweetman, G.; Kuster, B. Robust and sensitive iTRAQ quantification on an LTQ-Orbitrap mass spectrometer. Mol. Cell. Proteomics 2008, 7, 1702-1713.
45. Lu, B.W.; Motoyama, A.; Ruse, C.; Venable, J.; Yates, J.R.; III. Improving protein identification sensitivity by combining MS and MS/MS information for shotgun proteomics using LTQ-Orbitrap high mass accuracy data. Anal. Chem. 2008, 80, 2018-2025.
46. Cantin, G.T.; Yi, W.; Lu, B.W.; Park, S.K.; Xu, T.; Lee, J.D.; Yates, J.R. III. Combining protein-pased IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. J. Proteome Research 2008, 7, 1346-1351.
47. Waanders, L.F.; Hanke, S.; Mann, M. Top-down quantitation and characterization of SILAC-labeled proteins. J. Am. Soc. Mass Spectrom. 2007, 18, 2058-2064.
48. DiMaggio, P.A.; Floudas, C.A.; Lu, B.W.; Yates, J.R. III. A hybrid method for peptide identification using integer linear optimization, local database search, and quadrupole time-of-flight or Orbitrap tandem mass spectrometry. J. Proteome Research 2008, 7, 1584-1593.
49. Bondarenko, P.V.; Zabrouskov, V.; Makarov, A.; Zhang, Z. LC/MS top-down analysis and intact mass analysis of recombinant immunoglobulin gamma antibodies on Orbitrap. Proc. 56th ASMS Conference on Mass Spectrometry and Allied Topics, Denver, June 1-5, 2008.
50. Peterman, S.M.; Duczak, N.; Kalgutkar, A.S.; Lame, M.E.; Soglia, J.R. Application of a linear ion trap/Orbitrap mass spectrometer in metabolite characterization studies: examination of the human liver microsomal metabolism of the non-tricyclic anti-depressant nefazodone using data-dependent accurate mass measurements. J. Am. Soc. Mass Spectrom. 2006, 17, 363-375.
51. Lim, H-K.; Chen, J.; Sensenhauser, C.; Cook, K.; Subrahmanyam, V. Metabolite identification by data-dependent accurate mass spectrometric analysis at resolving power of 60000 in external calibration mode using an LTQ/Orbitrap. Rapid Comm. Mass Spectrom. 2007, 21, 1821-1832.
52. Breitling, R.; Pitt, A.R.; Barrett, M.P. Precision mapping of the metabolome. Trends Biotechnol. 2006, 24, 543-548.
53. Thevis, M.; Kamber, M.; Schaenzer, W. Screening for metabolically stable aryl-propionamide derived selective androgen receptor modulators for doping control purposes. Rapid Commun. Mass Spectrom. 2006, 20, 870-876.
54. Thevis, M.; Krug, O.; Schaenzer, W. Mass spectrometric characterization of efaproxiral (RSR13) and its implementation into doping controls using liquid chromatography-atmospheric pressure ionization-tandem mass spectrometry. J. Mass Spectrom. 2006, 41, 332-338.
55. Thevis, M.; Thomas, A.; Schanzer, W. Mass spectrometric determination of insulins and their degradation products in sports drug testing. Mass Spectrom. Rev. 2008, 27, 35-50.
56. Ejsing, C.; Moehring, T.; Bahr, U.; Duchoslav, E. Collision-induced dissociation pathways of yeast sphingolipids and their molecular profiling in total lipid extracts: a study by quadrupole TOF and linear ion trap-orbitrap mass spectrometry. J. Mass Spectrom. 2006, 41, 372-389.
57. Schwudke, D.; Hannich, J.T.; Surendranath, V.; Grimard, V.; Moehring, T.; Burton, L.; Kurzchalia, T.; Shevchenko, A. Top-down lipidomic screens by multivariate analysis of high-resolution survey mass spectra. Anal. Chem. 2007, 79, 4083-4093.
58. McAlister, G.; Berggren, W.; Griep-Raming, J.; Horning, S.; Makarov, A.; Phanstiel, D.; Stafford, G.; Swaney, D.; Syka, J.; Zabrouskov, V.; Coon, J. A proteomics grade electron transfer dissociation-enabled hybrid linear ion trap-Orbitrap mass spectrometer. J. Proteome Research 2008, 7, 3127-3136.
59. Strupat, K.; Bui, H.; Kovtoun, V.; Viner, R.; Prieto Conaway, M.C.; Izgarian, N.; Lange, O.; Stafford, G.; Horning, S.; Phillips, J.J.; Moehring, T. MALDI produced ions inspected with a linear ion trap-Orbitrap mass analyzer. Proc. 56th ASMS Conference on Mass Spectrometry and Allied Topics, Denver, June 1-5, 2008.
60. Wieghaus, A.; Makarov, A.A.; Froehlich, U.; Kellmann, M.; Denisov, E.; Lange, O. Development and applications of a new benchtop Orbitrap mass spectrometer. Proc. 56th ASMS Conference on Mass Spectrometry and Allied Topics, Denver, June 1-5, 2008.
61. Kellmann, M.; Taylor, L.; Ghosh, D.; Wieghaus, A.; Muenster, H. High resolution and high mass accuracy: a perfect team for food and feed analysis in complex matrices. Proc. 56th ASMS Conference on Mass Spectrometry and Allied Topics, Denver, June 1-5, 2008.
62. Bateman, K.; Muenster, H.; Kellmann, M.; Tiller, P.; Papp, R.; Taylor, L.C. Full scan data acquisition for rapid quantitative and qualitative analysis using a bench-top non-hybrid ESI-Orbitrap mass spectrometer. Proc. 56th ASMS Conference on Mass Spectrometry and Allied Topics, Denver, June 1-5, 2008.
63. Denisov, E.; Lange, O.; Makarov, A.; Balschun, W.; Griep-Raming, J. Performance of a high-field Orbitrap mass analyzer. Proc. 56th ASMS Conference on Mass Spectrometry and Allied Topics, Denver, June 1-5, 2008.