Atg5-mediated autophagy deficiency in proximal tubules promotes cell cycle G2/M arrest and renal fibrosis

Autophagy

Volumn 12, Issue 9, 2016, Pages 1472-1486

  Li, Huiyan ^a   Peng, Xuan ^a   Wang, Yating ^a   Cao, Shirong ^a   Xiong, Liping ^a   Fan, Jinjin ^a   Wang, Yihan ^b   Zhuang, Shougang ^c   Yu, Xueqing ^a   Mao, Haiping ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b Laboratory for Kidney Pathology Inc   (United States)

^c BROWN UNIVERSITY   (United States)

Author keywords

ATG5; autophagy; cell cycle; proximal tubular epithelial cells; renal fibrosis

Indexed keywords

ALOXISTATIN; AUTOPHAGY PROTEIN 5; COLLAGEN TYPE 1; HISTONE H3; PEPSTATIN; PROTEIN P62; RAPAMYCIN; ANGIOTENSIN II; ATG5 PROTEIN, HUMAN; ATG5 PROTEIN, MOUSE; AUTOPHAGY RELATED PROTEIN 5;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CELL CYCLE PROGRESSION; CELL POPULATION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; G1 PHASE CELL CYCLE CHECKPOINT; G2 PHASE CELL CYCLE CHECKPOINT; IMMUNOBLOTTING; IN VITRO STUDY; KIDNEY CORTEX; KIDNEY FIBROSIS; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; M PHASE CELL CYCLE CHECKPOINT; MALE; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RENAL PROTECTION; S PHASE CELL CYCLE CHECKPOINT; ANIMAL; C57BL MOUSE; CELL CYCLE; CELL CYCLE CHECKPOINT; CELL CYCLE G2 PHASE; CELL DIVISION; CHEMISTRY; EPITHELIUM CELL; FIBROSIS; GENE DELETION; GENETICS; HUMAN; KIDNEY; KIDNEY DISEASE; KIDNEY TUBULE; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ANGIOTENSIN II; ANIMALS; AUTOPHAGY; AUTOPHAGY-RELATED PROTEIN 5; CELL CYCLE; CELL CYCLE CHECKPOINTS; CELL DIVISION; COLLAGEN TYPE I; EPITHELIAL CELLS; FIBROSIS; G2 PHASE; GENE DELETION; HUMANS; KIDNEY; KIDNEY DISEASES; KIDNEY TUBULES; KIDNEY TUBULES, PROXIMAL; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; SIGNAL TRANSDUCTION; SIROLIMUS;

EID: 84978496745     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.1080/15548627.2016.1190071     Document Type: Article

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