An artificial niche preserves the quiescence of muscle stem cells and enhances their therapeutic efficacy

Nature Biotechnology

Volumn 34, Issue 7, 2016, Pages 752-759

  Quarta, Marco ^a,b   Brett, Jamie O ^a   DiMarco, Rebecca ^c   De Morree, Antoine ^a   Boutet, Stephane C ^a   Chacon, Robert ^a,b   Gibbons, Michael C ^a,b   Garcia, Victor A ^a,b   Su, James ^c   Shrager, Joseph B ^a   Heilshorn, Sarah ^c   Rando, Thomas A ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^c Stanford University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTIFICIAL INTELLIGENCE; CELLS; CYTOLOGY; LEARNING SYSTEMS; MAMMALS; MUSCLE; TISSUE; TISSUE ENGINEERING; TISSUE REGENERATION;

ENGINEERED FIBERS; GENETIC DISORDERS; MACHINE LEARNING METHODS; MOLECULAR SIGNATURES; MUSCLE FIBER; QUIESCENT STATE; THERAPEUTIC EFFICACY; THERAPEUTIC STRATEGY;

STEM CELLS;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ARTIFICIAL CELL; BIOLUMINESCENCE; CELL ENGINEERING; CELL FATE; CELL PROLIFERATION; CELL SURVIVAL; CELL TRANSPLANTATION; CELLULAR DISTRIBUTION; ENGRAFTMENT; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; MUSCLE STEM CELL; MUSCULAR DYSTROPHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; RANDOM FOREST; STEM CELL NICHE; STEM CELL SELF-RENEWAL; THERAPY EFFECT; TISSUE REGENERATION; ANIMAL; BATCH CELL CULTURE; C57BL MOUSE; CELL CULTURE; CYTOLOGY; METABOLISM; PHYSIOLOGY; PROCEDURES; SKELETAL MYOBLAST; STEM CELL TRANSPLANTATION; TISSUE PRESERVATION; TRANSPLANTATION; TREATMENT OUTCOME;

MUSCLE PROTEIN;

ANIMALS; BATCH CELL CULTURE TECHNIQUES; CELLS, CULTURED; MICE; MICE, INBRED C57BL; MUSCLE PROTEINS; MYOBLASTS, SKELETAL; STEM CELL NICHE; STEM CELL TRANSPLANTATION; TISSUE PRESERVATION; TREATMENT OUTCOME;

EID: 84978427825     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.3576     Document Type: Article

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