Silencing of microRNA-132 reduces renal fibrosis by selectively inhibiting myofibroblast proliferation

Kidney International

Volumn 89, Issue 6, 2016, Pages 1268-1280

  Bijkerk, Roel ^a,b   de Bruin, Ruben G ^a   van Solingen, Coen ^a   van Gils, Janine M ^a   Duijs, Jacques M G J ^a   van der Veer, Eric P ^a   Rabelink, Ton J ^a   Humphreys, Benjamin D ^b,c   van Zonneveld, Anton Jan ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

chronic kidney disease; fibrosis; transforming growth factor

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CELL PROTEIN; CYCLIN A; E1A ASSOCIATED P300 PROTEIN; KI 67 ANTIGEN; MICRORNA 132; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN P21; RASA1 PROTEIN; RB1 PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; STAT3 PROTEIN; TRANSCRIPTION FACTOR FKHRL1; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; ACTA2 PROTEIN, HUMAN; ACTIN; ALPHA-SMOOTH MUSCLE ACTIN, MOUSE; ANTAGOMIR; COLLAGEN; MICRORNA; MIRN132 MICRORNA, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE ACTIVITY; GENE FUNCTION; GENE IDENTIFICATION; GENE SILENCING; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; KIDNEY FIBROSIS; KIDNEY TUBULE CELL; MOLECULAR PATHOLOGY; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; APOPTOSIS; C57BL MOUSE; CELL LINE; CHRONIC KIDNEY FAILURE; EPITHELIUM CELL; FIBROBLAST; FIBROSIS; GENETICS; HUMAN; KIDNEY; KIDNEY TUBULE; METABOLISM; PATHOLOGY; PERICYTE; PHYSIOLOGY; RNA INTERFERENCE;

ACTINS; ANIMALS; ANTAGOMIRS; APOPTOSIS; CELL LINE; CELL PROLIFERATION; COLLAGEN; EPITHELIAL CELLS; FIBROBLASTS; FIBROSIS; HUMANS; IMMUNOHISTOCHEMISTRY; KIDNEY; KIDNEY TUBULES; MICE; MICE, INBRED C57BL; MICRORNAS; MYOFIBROBLASTS; PERICYTES; RENAL INSUFFICIENCY, CHRONIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 84978173029     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1016/j.kint.2016.01.029     Document Type: Article

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