Glycolipid-based TLR4 Modulators and Fluorescent Probes: Rational Design, Synthesis, and Biological Properties

Chemical Biology and Drug Design

Volumn 88, Issue 2, 2016, Pages 217-229

  Ciaramelli, Carlotta ^a   Calabrese, Valentina ^a   Sestito, Stefania E ^a   Pérez Regidor, Lucia ^b,c   Klett, Javier ^b,c   Oblak, Alja ^d   Jerala, Roman ^d   Piazza, Matteo ^a   Martín Santamaría, Sonsoles ^b,c   Peri, Francesco ^a  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b UNIVERSIDAD SAN PABLO CEU   (Spain)

^c CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^d NATIONAL INSTITUTE OF CHEMISTRY   (Slovenia)

Author keywords

antagonists; computational chemistry; fluorescent chemical probes; glycolipids; HEK TLR4 cells; MD 2; medicinal chemistry; TLR4

Indexed keywords

CD14 ANTIGEN; CELL SURFACE PROTEIN; FLUORESCEIN; FLUORESCENT DYE; GLYCOLIPID; IAXO 102; LIPOPOLYSACCHARIDE; MEMBRANE PROTEIN; PROTEIN MD 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR AFFECTING AGENT; TRYPSIN; UNCLASSIFIED DRUG; TLR4 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; DRUG BINDING; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; FLUORESCENCE; HUMAN; HUMAN CELL; MACROPHAGE; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; CELL LINE; CHEMISTRY;

ANIMALS; CELL LINE; DRUG DESIGN; FLUORESCENT DYES; GLYCOLIPIDS; HUMANS; MICE; TOLL-LIKE RECEPTOR 4;

EID: 84978171098     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/cbdd.12749     Document Type: Article

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