Elevated Angiopoietin-2 Level in Patients with Continuous-Flow Left Ventricular Assist Devices Leads to Altered Angiogenesis and Is Associated with Higher Nonsurgical Bleeding

Circulation

Volumn 134, Issue 2, 2016, Pages 141-152

  Tabit, Corey E ^a   Chen, Phetcharat ^a   Kim, Gene H ^a   Fedson, Savitri E ^b   Sayer, Gabriel ^a   Coplan, Mitchell J ^a   Jeevanandam, Valluvan ^b   Uriel, Nir ^a   Liao, James K ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

angiogenesis; angiopoietin 2; cardiac transplant; LVAD; nonsurgical bleeding; thrombin

Indexed keywords

ANGIOPOIETIN 2; BIOLOGICAL MARKER; THROMBIN; VORAPAXAR;

ADULT; ANGIOGENESIS; ARTERIOVENOUS MALFORMATION; ARTICLE; BLEEDING; BLOOD SAMPLING; CARDIAC PATIENT; COMPARATIVE STUDY; CONTINUOUS FLOW LEFT VENTRICULAR ASSIST DEVICE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION; HEART FAILURE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART TRANSPLANTATION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; IMMUNOFLUORESCENCE; IN VITRO STUDY; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; NEW YORK HEART ASSOCIATION CLASS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURGICAL PATIENT; UMBILICAL VEIN ENDOTHELIAL CELL; WESTERN BLOTTING; AGED; BIOSYNTHESIS; BLOOD; COMPLICATION; GENETICS; HEART ASSIST DEVICE; HEMORRHAGE; METABOLISM; NEOVASCULARIZATION, PATHOLOGIC; PATHOPHYSIOLOGY;

AGED; ANGIOPOIETIN-2; ARTERIOVENOUS MALFORMATIONS; BIOMARKERS; CROSS-SECTIONAL STUDIES; ENDOTHELIAL CELLS; FEMALE; HEART-ASSIST DEVICES; HEMORRHAGE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MALE; MIDDLE AGED; NEOVASCULARIZATION, PATHOLOGIC; THROMBIN;

EID: 84978161622     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.115.019692     Document Type: Article

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