-
1
-
-
0028122465
-
Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo
-
Dumont DJ, et al. Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo. Genes Dev. 1994;8(16):1897-1909.
-
(1994)
Genes Dev
, vol.8
, Issue.16
, pp. 1897-1909
-
-
Dumont, D.J.1
-
2
-
-
0029001244
-
Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation
-
Sato TN, et al. Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation. Nature. 1995;376(6535):70-74.
-
(1995)
Nature
, vol.376
, Issue.6535
, pp. 70-74
-
-
Sato, T.N.1
-
3
-
-
79957880117
-
Angiopoietin-1 is essential in mouse vasculature during development and in response to injury
-
Jeansson M, et al. Angiopoietin-1 is essential in mouse vasculature during development and in response to injury. J Clin Invest. 2011; 121(6):2278-2289.
-
(2011)
J Clin Invest
, vol.121
, Issue.6
, pp. 2278-2289
-
-
Jeansson, M.1
-
4
-
-
0030480322
-
Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis
-
Suri C, et al. Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell. 1996;87(7):1171-1180.
-
(1996)
Cell
, vol.87
, Issue.7
, pp. 1171-1180
-
-
Suri, C.1
-
5
-
-
15144358851
-
Angiopoietin-2, a Natural Antagonist for Tie2 That Disrupts in vivo Angiogenesis
-
Maisonpierre PC, et al. Angiopoietin-2, a Natural Antagonist for Tie2 That Disrupts in vivo Angiogenesis. Science. 1997;277(5322):55-60.
-
(1997)
Science
, vol.277
, Issue.5322
, pp. 55-60
-
-
Maisonpierre, P.C.1
-
6
-
-
77954930620
-
Angiopoietin-2 stimulation of endothelial cells induces alphavbeta3 integrin internalization and degradation
-
Thomas M, et al. Angiopoietin-2 stimulation of endothelial cells induces alphavbeta3 integrin internalization and degradation. J Biol Chem. 2010;285(31):23842-23849.
-
(2010)
J Biol Chem
, vol.285
, Issue.31
, pp. 23842-23849
-
-
Thomas, M.1
-
7
-
-
84861820220
-
Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling
-
Felcht M, et al. Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling. J Clin Invest. 2012;122(6):1991-2005.
-
(2012)
J Clin Invest
, vol.122
, Issue.6
, pp. 1991-2005
-
-
Felcht, M.1
-
8
-
-
33645355399
-
Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans
-
Parikh SM, et al. Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans. PLoS Med. 2006;3(3):e46.
-
(2006)
PLoS Med
, vol.3
, Issue.3
-
-
Parikh, S.M.1
-
9
-
-
77951207233
-
Angiopoietin-2 in patients requiring renal replacement therapy in the ICU: Relation to acute kidney injury, multiple organ dysfunction syndrome and outcome
-
Kumpers P, et al. Angiopoietin-2 in patients requiring renal replacement therapy in the ICU: relation to acute kidney injury, multiple organ dysfunction syndrome and outcome. Intensive Care Med. 2010;36(3):462-470.
-
(2010)
Intensive Care Med
, vol.36
, Issue.3
, pp. 462-470
-
-
Kumpers, P.1
-
10
-
-
77952692518
-
Imbalances in serum angiopoietin concentrations are early predictors of septic shock development in patients with post chemotherapy febrile neutropenia
-
Alves BE, et al. Imbalances in serum angiopoietin concentrations are early predictors of septic shock development in patients with post chemotherapy febrile neutropenia. BMC Infect Dis. 2010;10:143.
-
(2010)
BMC Infect Dis
, vol.10
, pp. 143
-
-
Alves, B.E.1
-
11
-
-
77149131838
-
The interaction of soluble Tie2 with angiopoietins and pulmonary vascular permeability in septic and nonseptic critically ill patients
-
van der Heijden M, van Nieuw Amerongen GP, Van Hinsbergh VW, Groeneveld AB. The interaction of soluble Tie2 with angiopoietins and pulmonary vascular permeability in septic and nonseptic critically ill patients. Shock. 2010;33(3):263-268.
-
(2010)
Shock
, vol.33
, Issue.3
, pp. 263-268
-
-
Van Der Heijden, M.1
Van Nieuw Amerongen, G.P.2
Van Hinsbergh, V.W.3
Groeneveld, A.B.4
-
12
-
-
78649467527
-
Pericytes regulate the blood-brain barrier
-
Armulik A, et al. Pericytes regulate the blood-brain barrier. Nature. 2010;468(7323):557-561.
-
(2010)
Nature
, vol.468
, Issue.7323
, pp. 557-561
-
-
Armulik, A.1
-
13
-
-
22944432543
-
Angiopoietin-2 causes inflammation in vivo by promoting vascular leakage
-
Roviezzo F, et al. Angiopoietin-2 causes inflammation in vivo by promoting vascular leakage. J Pharmacol Exp Ther. 2005;314(2):738-744.
-
(2005)
J Pharmacol Exp Ther
, vol.314
, Issue.2
, pp. 738-744
-
-
Roviezzo, F.1
-
14
-
-
0033601357
-
Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin- 1
-
Thurston G, et al. Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin- 1. Science. 1999;286(5449):2511-2514.
-
(1999)
Science
, vol.286
, Issue.5449
, pp. 2511-2514
-
-
Thurston, G.1
-
15
-
-
0036223819
-
Stable expression of angiopoietin-1 and other markers by cultured pericytes: Phenotypic similarities to a subpopulation of cells in maturing vessels during later stages of angiogenesis in vivo
-
Sundberg C, Kowanetz M, Brown LF, Detmar M, Dvorak HF. Stable expression of angiopoietin-1 and other markers by cultured pericytes: phenotypic similarities to a subpopulation of cells in maturing vessels during later stages of angiogenesis in vivo. Lab Invest. 2002;82(4):387-401.
-
(2002)
Lab Invest
, vol.82
, Issue.4
, pp. 387-401
-
-
Sundberg, C.1
Kowanetz, M.2
Brown, L.F.3
Detmar, M.4
Dvorak, H.F.5
-
16
-
-
12144286666
-
Angiopoietin-2 causes pericyte dropout in the normal retina: Evidence for involvement in diabetic retinopathy
-
Hammes HP, et al. Angiopoietin-2 causes pericyte dropout in the normal retina: evidence for involvement in diabetic retinopathy. Diabetes. 2004;53(4):1104-1110.
-
(2004)
Diabetes
, vol.53
, Issue.4
, pp. 1104-1110
-
-
Hammes, H.P.1
-
17
-
-
0035164912
-
A novel transgenic marker for migrating limb muscle precursors and for vascular smooth muscle cells
-
Tidhar A, et al. A novel transgenic marker for migrating limb muscle precursors and for vascular smooth muscle cells. Dev Dyn. 2001;220(1):60-73.
-
(2001)
Dev Dyn
, vol.220
, Issue.1
, pp. 60-73
-
-
Tidhar, A.1
-
18
-
-
33847006938
-
Impaired pericyte recruitment and abnormal retinal angiogenesis as a result of angiopoietin-2 overexpression
-
Feng Y, et al. Impaired pericyte recruitment and abnormal retinal angiogenesis as a result of angiopoietin-2 overexpression. Thromb Haemost. 2007;97(1):99-108.
-
(2007)
Thromb Haemost
, vol.97
, Issue.1
, pp. 99-108
-
-
Feng, Y.1
-
19
-
-
79959376030
-
Pericyte requirement for anti-leak action of angiopoietin-1 and vascular remodeling in sustained inflammation
-
Fuxe J, et al. Pericyte requirement for anti-leak action of angiopoietin-1 and vascular remodeling in sustained inflammation. Am J Pathol. 2011;178(6):2897-2909.
-
(2011)
Am J Pathol
, vol.178
, Issue.6
, pp. 2897-2909
-
-
Fuxe, J.1
-
20
-
-
79961230399
-
Pericytes: Developmental, physiological, and pathological perspectives, problems, and promises
-
Armulik A, Genove G, Betsholtz C. Pericytes: developmental, physiological, and pathological perspectives, problems, and promises. Dev Cell. 2011;21(2):193-215.
-
(2011)
Dev Cell
, vol.21
, Issue.2
, pp. 193-215
-
-
Armulik, A.1
Genove, G.2
Betsholtz, C.3
-
21
-
-
66249134941
-
Time course of angiopoietin-2 release during experimental human endotoxemia and sepsis
-
Kumpers P, et al. Time course of angiopoietin-2 release during experimental human endotoxemia and sepsis. Crit Care. 2009;13(3):R64.
-
(2009)
Crit Care
, vol.13
, Issue.3
-
-
Kumpers, P.1
-
22
-
-
11244337801
-
Protective role of angiopoietin-1 in endotoxic shock
-
Witzenbichler B, Westermann D, Knueppel S, Schultheiss HP, Tschope C. Protective role of angiopoietin-1 in endotoxic shock. Circulation. 2005;111(1):97-105.
-
(2005)
Circulation
, vol.111
, Issue.1
, pp. 97-105
-
-
Witzenbichler, B.1
Westermann, D.2
Knueppel, S.3
Schultheiss, H.P.4
Tschope, C.5
-
23
-
-
79959546082
-
Acute administration of recombinant Angiopoietin-1 ameliorates multiple-organ dysfunction syndrome and improves survival in murine sepsis
-
David S, et al. Acute administration of recombinant Angiopoietin-1 ameliorates multiple-organ dysfunction syndrome and improves survival in murine sepsis. Cytokine. 2011;55(2):251-259.
-
(2011)
Cytokine
, vol.55
, Issue.2
, pp. 251-259
-
-
David, S.1
-
24
-
-
77955005442
-
Hepcidin mediates transcriptional changes that modulate acute cytokine-induced inflammatory responses in mice
-
De Domenico I, et al. Hepcidin mediates transcriptional changes that modulate acute cytokine-induced inflammatory responses in mice. J Clin Invest. 2010;120(7):2395-2405.
-
(2010)
J Clin Invest
, vol.120
, Issue.7
, pp. 2395-2405
-
-
De Domenico, I.1
-
25
-
-
84867609127
-
Angiopoietin-2 enhances survival in experimental sepsis induced by multidrug-resistant Pseudomonas aeruginosa
-
Tzepi IM, et al. Angiopoietin-2 enhances survival in experimental sepsis induced by multidrug-resistant Pseudomonas aeruginosa. J Pharmacol Exp Ther. 2012;343(2):278-287.
-
(2012)
J Pharmacol Exp Ther
, vol.343
, Issue.2
, pp. 278-287
-
-
Tzepi, I.M.1
-
26
-
-
84861375592
-
Angiopoietin-1 mediates inhibition of hypertension-induced release of angiopoietin- 2 from endothelial cells
-
Korff T, et al. Angiopoietin-1 mediates inhibition of hypertension-induced release of angiopoietin- 2 from endothelial cells. Cardiovasc Res. 2012;94(3):510-518.
-
(2012)
Cardiovasc Res
, vol.94
, Issue.3
, pp. 510-518
-
-
Korff, T.1
-
27
-
-
34447643563
-
Angiopoietin-2 impairs revascularization after limb ischemia
-
Reiss Y, et al. Angiopoietin-2 impairs revascularization after limb ischemia. Circ Res. 2007;101(1):88-96.
-
(2007)
Circ Res
, vol.101
, Issue.1
, pp. 88-96
-
-
Reiss, Y.1
-
28
-
-
79951920752
-
Pericyte-mediated vasoconstriction underlies TBI-induced hypoperfusion
-
Dore-Duffy P, et al. Pericyte-mediated vasoconstriction underlies TBI-induced hypoperfusion. Neurol Res. 2011;33(2):176-186.
-
(2011)
Neurol Res
, vol.33
, Issue.2
, pp. 176-186
-
-
Dore-Duffy, P.1
-
29
-
-
2642597076
-
Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells
-
Papapetropoulos A, Garcia-Cardena G, Madri JA, Sessa WC. Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells. J Clin Invest. 1997;100(12):3131-3139.
-
(1997)
J Clin Invest
, vol.100
, Issue.12
, pp. 3131-3139
-
-
Papapetropoulos, A.1
Garcia-Cardena, G.2
Madri, J.A.3
Sessa, W.C.4
-
30
-
-
0031008458
-
Nitric oxide synthase lies downstream from vascular endothelial growth factor- induced but not basic fibroblast growth factor-induced angiogenesis
-
Ziche M, et al. Nitric oxide synthase lies downstream from vascular endothelial growth factor- induced but not basic fibroblast growth factor-induced angiogenesis. J Clin Invest. 1997; 99(11):2625-2634.
-
(1997)
J Clin Invest
, vol.99
, Issue.11
, pp. 2625-2634
-
-
Ziche, M.1
-
31
-
-
33751260905
-
Hemodynamic effects of intracoronary VEGF delivery: Evidence of tachyphylaxis and NO dependence of response
-
Lopez JJ, et al. Hemodynamic effects of intracoronary VEGF delivery: evidence of tachyphylaxis and NO dependence of response. Am J Physiol. 1997;273(3 pt 2):H1317-H1323.
-
(1997)
Am J Physiol
, vol.273
, Issue.3 PART 2
-
-
Lopez, J.J.1
-
32
-
-
0035131299
-
Efficacy of intracoronary or intravenous VEGF165 in a pig model of chronic myocardial ischemia
-
Sato K, et al. Efficacy of intracoronary or intravenous VEGF165 in a pig model of chronic myocardial ischemia. J Am Coll Cardiol. 2001;37(2):616-623.
-
(2001)
J Am Coll Cardiol
, vol.37
, Issue.2
, pp. 616-623
-
-
Sato, K.1
-
33
-
-
67650248913
-
Angiopoietin-2 Confers atheroprotection in apoE-/- mice by inhibiting ldl oxidation via nitric oxide
-
Ahmed A, et al. Angiopoietin-2 Confers atheroprotection in apoE-/- mice by inhibiting ldl oxidation via nitric oxide. Circ Res. 2009;104(12):1333-1336.
-
(2009)
Circ Res
, vol.104
, Issue.12
, pp. 1333-1336
-
-
Ahmed, A.1
-
34
-
-
23344452702
-
Endothelial nitric oxide synthase is critical for ischemic remodeling, mural cell recruitment, and blood flow reserve
-
Yu J, et al. Endothelial nitric oxide synthase is critical for ischemic remodeling, mural cell recruitment, and blood flow reserve. Proc Natl Acad Sci U S A. 2005;102(31):10999-11004.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.31
, pp. 10999-11004
-
-
Yu, J.1
-
35
-
-
0042125242
-
Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wall
-
Lindblom P, et al. Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wall. Gene Dev. 2003;17(15):1835- 1840.
-
(2003)
Gene Dev
, vol.17
, Issue.15
, pp. 1835-1840
-
-
Lindblom, P.1
-
36
-
-
33746290485
-
Platelet-derived growth factor B retention is essential for development of normal structure and function of conduit vessels and capillaries
-
Nystrom HC, et al. Platelet-derived growth factor B retention is essential for development of normal structure and function of conduit vessels and capillaries. Cardiovasc Res. 2006;71(3):557-565.
-
(2006)
Cardiovasc Res
, vol.71
, Issue.3
, pp. 557-565
-
-
Nystrom, H.C.1
-
37
-
-
0028943808
-
Vascular endothelial cell lineage-specific promoter in transgenic mice
-
Schlaeger TM, Qin Y, Fujiwara Y, Magram J, Sato TN. Vascular endothelial cell lineage-specific promoter in transgenic mice. Development. 1995;121(4):1089-1098.
-
(1995)
Development
, vol.121
, Issue.4
, pp. 1089-1098
-
-
Schlaeger, T.M.1
Qin, Y.2
Fujiwara, Y.3
Magram, J.4
Sato, T.N.5
-
38
-
-
40049098305
-
Inducible endothelial cell-specific gene expression in transgenic mouse embryos and adult mice
-
Deutsch U, et al. Inducible endothelial cell-specific gene expression in transgenic mouse embryos and adult mice. Exp Cell Res. 2008;314(6):1202-1216.
-
(2008)
Exp Cell Res
, vol.314
, Issue.6
, pp. 1202-1216
-
-
Deutsch, U.1
-
39
-
-
0029816480
-
Conditional transgene expression in the heart
-
Yu Z, Redfern CS, Fishman GI. Conditional transgene expression in the heart. Circ Res. 1996;79(4):691-697.
-
(1996)
Circ Res
, vol.79
, Issue.4
, pp. 691-697
-
-
Yu, Z.1
Redfern, C.S.2
Fishman, G.I.3
-
40
-
-
84155162827
-
Mitochondrial thioredoxin reductase is essential for early postischemic myocardial protection
-
Horstkotte J, et al. Mitochondrial thioredoxin reductase is essential for early postischemic myocardial protection. Circulation. 2011;124(25):2892-2902.
-
(2011)
Circulation
, vol.124
, Issue.25
, pp. 2892-2902
-
-
Horstkotte, J.1
-
41
-
-
62949195390
-
Synergy between CD26/DPP-IV inhibition and G-CSF improves cardiac function after acute myocardial infarction
-
Zaruba MM, et al. Synergy between CD26/DPP-IV inhibition and G-CSF improves cardiac function after acute myocardial infarction. Cell Stem Cell. 2009;4(4):313-323.
-
(2009)
Cell Stem Cell
, vol.4
, Issue.4
, pp. 313-323
-
-
Zaruba, M.M.1
-
42
-
-
82155170442
-
Labelfree 3D visualization of cellular and tissue structures in intact muscle with second and third harmonic generation microscopy
-
Rehberg M, Krombach F, Pohl U, Dietzel S. Labelfree 3D visualization of cellular and tissue structures in intact muscle with second and third harmonic generation microscopy. PLoS One. 2011;6(11):e28237.
-
(2011)
PLoS One
, vol.6
, Issue.11
-
-
Rehberg, M.1
Krombach, F.2
Pohl, U.3
Dietzel, S.4
-
43
-
-
57749169283
-
AAV9 provides global cardiac gene transfer superior to AAV1, AAV6, AAV7, and AAV8 in the mouse and rat
-
Bish LT, et al. AAV9 provides global cardiac gene transfer superior to AAV1, AAV6, AAV7, and AAV8 in the mouse and rat. Hum Gene Ther. 2008;19(12):1359-1368.
-
(2008)
Hum Gene Ther
, vol.19
, Issue.12
, pp. 1359-1368
-
-
Bish, L.T.1
-
44
-
-
84873545836
-
A novel angiopoietin-2 selective fully human antibody with potent anti-tumoral and anti-angiogenic efficacy and superior side effect profile compared to pan-angiopoietin-1/-2 inhibitors
-
Thomas M, et al. A novel angiopoietin-2 selective fully human antibody with potent anti-tumoral and anti-angiogenic efficacy and superior side effect profile compared to pan-angiopoietin-1/-2 inhibitors. PLoS One. 2013;8(2):e54923.
-
(2013)
PLoS One
, vol.8
, Issue.2
-
-
Thomas, M.1
|