메뉴 건너뛰기




Volumn 7, Issue 24, 2016, Pages 36940-36955

Estrogen regulates miRNA expression: Implication of estrogen receptor and miR-124/AKT2 in tumor growth and angiogenesis

Author keywords

AKT2; Breast cancer; Estrogen; Estrogen receptors; MiR 124

Indexed keywords

ANTIBODY; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; MICRORNA 124; MICRORNA 124 ANTIBODY; PROTEIN KINASE B BETA; UNCLASSIFIED DRUG; AKT2 PROTEIN, HUMAN; MICRORNA; MIRN124 MICRORNA, HUMAN; PROTEIN KINASE B;

EID: 84978143552     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.9230     Document Type: Article
Times cited : (45)

References (45)
  • 2
    • 0035945656 scopus 로고    scopus 로고
    • Estrogen and the risk of breast cancer
    • Clemons M and Goss P. Estrogen and the risk of breast cancer. N Engl J Med. 2001; 344:276-285.
    • (2001) N Engl J Med , vol.344 , pp. 276-285
    • Clemons, M.1    Goss, P.2
  • 3
    • 30944469849 scopus 로고    scopus 로고
    • Estrogen carcinogenesis in breast cancer
    • Yager JD and Davidson NE. Estrogen carcinogenesis in breast cancer. N Engl J Med. 2006; 354:270-282.
    • (2006) N Engl J Med , vol.354 , pp. 270-282
    • Yager, J.D.1    Davidson, N.E.2
  • 4
    • 0034751220 scopus 로고    scopus 로고
    • Estrogen receptor and breast cancer
    • Sommer S and Fuqua SA. Estrogen receptor and breast cancer. Semin Cancer Biol. 2001; 11:339-352.
    • (2001) Semin Cancer Biol , vol.11 , pp. 339-352
    • Sommer, S.1    Fuqua, S.A.2
  • 6
    • 62749085753 scopus 로고    scopus 로고
    • Breast cancer, estrogen receptor and ligands
    • Bai Z and Gust R. Breast cancer, estrogen receptor and ligands. Arch Pharm (Weinheim). 2009; 342:133-149.
    • (2009) Arch Pharm (Weinheim) , vol.342 , pp. 133-149
    • Bai, Z.1    Gust, R.2
  • 9
    • 39149132132 scopus 로고    scopus 로고
    • Estrogen induces repression of the breast cancer and salivary gland expression gene in an estrogen receptor alpha-dependent manner
    • Bretschneider N, Brand H, Miller N, Lowery AJ, Kerin MJ, Gannon F and Denger S. Estrogen induces repression of the breast cancer and salivary gland expression gene in an estrogen receptor alpha-dependent manner. Cancer Res. 2008; 68:106-114.
    • (2008) Cancer Res , vol.68 , pp. 106-114
    • Bretschneider, N.1    Brand, H.2    Miller, N.3    Lowery, A.J.4    Kerin, M.J.5    Gannon, F.6    Denger, S.7
  • 11
    • 34250681785 scopus 로고    scopus 로고
    • Association between the estrogen receptor alpha A908G mutation and outcomes in invasive breast cancer
    • Herynk MH, Parra I, Cui Y, Beyer A, Wu MF, Hilsenbeck SG and Fuqua SA. Association between the estrogen receptor alpha A908G mutation and outcomes in invasive breast cancer. Clin Cancer Res. 2007; 13:3235-3243.
    • (2007) Clin Cancer Res , vol.13 , pp. 3235-3243
    • Herynk, M.H.1    Parra, I.2    Cui, Y.3    Beyer, A.4    Wu, M.F.5    Hilsenbeck, S.G.6    Fuqua, S.A.7
  • 13
    • 0037505736 scopus 로고    scopus 로고
    • p53-independent activation of the hdm2-P2 promoter through multiple transcription factor response elements results in elevated hdm2 expression in estrogen receptor alpha-positive breast cancer cells
    • Phelps M, Darley M, Primrose JN and Blaydes JP. p53-independent activation of the hdm2-P2 promoter through multiple transcription factor response elements results in elevated hdm2 expression in estrogen receptor alpha-positive breast cancer cells. Cancer Res. 2003; 63:2616-2623.
    • (2003) Cancer Res , vol.63 , pp. 2616-2623
    • Phelps, M.1    Darley, M.2    Primrose, J.N.3    Blaydes, J.P.4
  • 14
    • 60149088848 scopus 로고    scopus 로고
    • Origins and Mechanisms of miRNAs and siRNAs
    • Carthew RW and Sontheimer EJ. Origins and Mechanisms of miRNAs and siRNAs. Cell. 2009; 136:642-655.
    • (2009) Cell , vol.136 , pp. 642-655
    • Carthew, R.W.1    Sontheimer, E.J.2
  • 15
    • 34848837296 scopus 로고    scopus 로고
    • miRNAs get an early start on translational silencing
    • Meister G. miRNAs get an early start on translational silencing. Cell. 2007; 131:25-28.
    • (2007) Cell , vol.131 , pp. 25-28
    • Meister, G.1
  • 16
    • 22144461002 scopus 로고    scopus 로고
    • miRNAs, cancer, and stem cell division
    • Croce CM and Calin GA. miRNAs, cancer, and stem cell division. Cell. 2005; 122:6-7.
    • (2005) Cell , vol.122 , pp. 6-7
    • Croce, C.M.1    Calin, G.A.2
  • 19
    • 79956313718 scopus 로고    scopus 로고
    • Up-regulation of miR-21 mediates resistance to trastuzumab therapy for breast cancer
    • Gong C, Yao Y, Wang Y, Liu B, Wu W, Chen J, Su F, Yao H and Song E. Up-regulation of miR-21 mediates resistance to trastuzumab therapy for breast cancer. J Biol Chem. 2011; 286:19127-19137.
    • (2011) J Biol Chem , vol.286 , pp. 19127-19137
    • Gong, C.1    Yao, Y.2    Wang, Y.3    Liu, B.4    Wu, W.5    Chen, J.6    Su, F.7    Yao, H.8    Song, E.9
  • 20
    • 55549120234 scopus 로고    scopus 로고
    • MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis
    • Yan LX, Huang XF, Shao Q, Huang MY, Deng L, Wu QL, Zeng YX and Shao JY. MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis. RNA. 2008; 14:2348-2360.
    • (2008) RNA , vol.14 , pp. 2348-2360
    • Yan, L.X.1    Huang, X.F.2    Shao, Q.3    Huang, M.Y.4    Deng, L.5    Wu, Q.L.6    Zeng, Y.X.7    Shao, J.Y.8
  • 21
    • 84896041322 scopus 로고    scopus 로고
    • miR-125b/Ets1 axis regulates transdifferentiation and calcification of vascular smooth muscle cells in a high-phosphate environment
    • Wen P, Cao H, Fang L, Ye H, Zhou Y, Jiang L, Su W, Xu H, He W, Dai C and Yang J. miR-125b/Ets1 axis regulates transdifferentiation and calcification of vascular smooth muscle cells in a high-phosphate environment. Exp Cell Res. 2014; 322:302-312.
    • (2014) Exp Cell Res , vol.322 , pp. 302-312
    • Wen, P.1    Cao, H.2    Fang, L.3    Ye, H.4    Zhou, Y.5    Jiang, L.6    Su, W.7    Xu, H.8    He, W.9    Dai, C.10    Yang, J.11
  • 23
    • 84860386584 scopus 로고    scopus 로고
    • miRNAs and estrogen action
    • Klinge CM. miRNAs and estrogen action. Trends Endocrinol Metab. 2012; 23:223-233.
    • (2012) Trends Endocrinol Metab , vol.23 , pp. 223-233
    • Klinge, C.M.1
  • 24
    • 79955836460 scopus 로고    scopus 로고
    • A rapid, extensive, and transient transcriptional response to estrogen signaling in breast cancer cells
    • Hah N, Danko CG, Core L, Waterfall JJ, Siepel A, Lis JT and Kraus WL. A rapid, extensive, and transient transcriptional response to estrogen signaling in breast cancer cells. Cell. 2011; 145:622-634.
    • (2011) Cell , vol.145 , pp. 622-634
    • Hah, N.1    Danko, C.G.2    Core, L.3    Waterfall, J.J.4    Siepel, A.5    Lis, J.T.6    Kraus, W.L.7
  • 27
    • 84884544457 scopus 로고    scopus 로고
    • Estrogen receptor alpha regulates ATM Expression through miRNAs in breast cancer
    • Guo X, Yang C, Qian X, Lei T, Li Y, Shen H, Fu L and Xu B. Estrogen receptor alpha regulates ATM Expression through miRNAs in breast cancer. Clin Cancer Res. 2013; 19:4994-5002.
    • (2013) Clin Cancer Res , vol.19 , pp. 4994-5002
    • Guo, X.1    Yang, C.2    Qian, X.3    Lei, T.4    Li, Y.5    Shen, H.6    Fu, L.7    Xu, B.8
  • 28
    • 48549099077 scopus 로고    scopus 로고
    • miR-206 Expression is down-regulated in estrogen receptor alpha-positive human breast cancer
    • Kondo N, Toyama T, Sugiura H, Fujii Y and Yamashita H. miR-206 Expression is down-regulated in estrogen receptor alpha-positive human breast cancer. Cancer Res. 2008; 68:5004-5008.
    • (2008) Cancer Res , vol.68 , pp. 5004-5008
    • Kondo, N.1    Toyama, T.2    Sugiura, H.3    Fujii, Y.4    Yamashita, H.5
  • 31
    • 84897018932 scopus 로고    scopus 로고
    • Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and metastasis by targeting Rac1
    • Wang P, Chen L, Zhang J, Chen H, Fan J, Wang K, Luo J, Chen Z, Meng Z and Liu L. Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and metastasis by targeting Rac1. Oncogene. 2014; 33:514-524.
    • (2014) Oncogene , vol.33 , pp. 514-524
    • Wang, P.1    Chen, L.2    Zhang, J.3    Chen, H.4    Fan, J.5    Wang, K.6    Luo, J.7    Chen, Z.8    Meng, Z.9    Liu, L.10
  • 32
    • 84871067207 scopus 로고    scopus 로고
    • miR-124 suppresses multiple steps of breast cancer metastasis by targeting a cohort of pro-metastatic genes in vitro
    • Lv XB, Jiao Y, Qing Y, Hu H, Cui X, Lin T, Song E and Yu F. miR-124 suppresses multiple steps of breast cancer metastasis by targeting a cohort of pro-metastatic genes in vitro. Chin J Cancer. 2011; 30:821-830.
    • (2011) Chin J Cancer , vol.30 , pp. 821-830
    • Lv, X.B.1    Jiao, Y.2    Qing, Y.3    Hu, H.4    Cui, X.5    Lin, T.6    Song, E.7    Yu, F.8
  • 36
    • 0035881568 scopus 로고    scopus 로고
    • Phosphatidylinositol-3-OH Kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K
    • Sun M, Paciga JE, Feldman RI, Yuan Z, Coppola D, Lu YY, Shelley SA, Nicosia SV and Cheng JQ. Phosphatidylinositol-3-OH Kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K. Cancer Res. 2001; 61:5985-5991.
    • (2001) Cancer Res , vol.61 , pp. 5985-5991
    • Sun, M.1    Paciga, J.E.2    Feldman, R.I.3    Yuan, Z.4    Coppola, D.5    Lu, Y.Y.6    Shelley, S.A.7    Nicosia, S.V.8    Cheng, J.Q.9
  • 37
    • 75149198825 scopus 로고    scopus 로고
    • Akt2 inhibition enables the forkhead transcription factor FoxO3a to have a repressive role in estrogen receptor alpha transcriptional activity in breast cancer cells
    • Morelli C, Lanzino M, Garofalo C, Maris P, Brunelli E, Casaburi I, Catalano S, Bruno R, Sisci D and Ando S. Akt2 inhibition enables the forkhead transcription factor FoxO3a to have a repressive role in estrogen receptor alpha transcriptional activity in breast cancer cells. Mol Cell Biol. 2010; 30:857-870.
    • (2010) Mol Cell Biol , vol.30 , pp. 857-870
    • Morelli, C.1    Lanzino, M.2    Garofalo, C.3    Maris, P.4    Brunelli, E.5    Casaburi, I.6    Catalano, S.7    Bruno, R.8    Sisci, D.9    Ando, S.10
  • 39
    • 0036185848 scopus 로고    scopus 로고
    • The protein kinase B/Akt signalling pathway in human malignancy
    • Nicholson KM and Anderson NG. The protein kinase B/Akt signalling pathway in human malignancy. Cell Signal. 2002; 14:381-395.
    • (2002) Cell Signal , vol.14 , pp. 381-395
    • Nicholson, K.M.1    Anderson, N.G.2
  • 40
    • 33947192053 scopus 로고    scopus 로고
    • Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel
    • Cheng GZ, Chan J, Wang Q, Zhang W, Sun CD and Wang LH. Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel. Cancer Res. 2007; 67:1979-1987.
    • (2007) Cancer Res , vol.67 , pp. 1979-1987
    • Cheng, G.Z.1    Chan, J.2    Wang, Q.3    Zhang, W.4    Sun, C.D.5    Wang, L.H.6
  • 41
    • 0037229714 scopus 로고    scopus 로고
    • Overexpression of AKT2/protein kinase Bbeta leads to up-regulation of beta1 integrins, increased invasion, and metastasis of human breast and ovarian cancer cells
    • Arboleda MJ, Lyons JF, Kabbinavar FF, Bray MR, Snow BE, Ayala R, Danino M, Karlan BY and Slamon DJ. Overexpression of AKT2/protein kinase Bbeta leads to up-regulation of beta1 integrins, increased invasion, and metastasis of human breast and ovarian cancer cells. Cancer Res. 2003; 63:196-206.
    • (2003) Cancer Res , vol.63 , pp. 196-206
    • Arboleda, M.J.1    Lyons, J.F.2    Kabbinavar, F.F.3    Bray, M.R.4    Snow, B.E.5    Ayala, R.6    Danino, M.7    Karlan, B.Y.8    Slamon, D.J.9
  • 44
    • 62549130754 scopus 로고    scopus 로고
    • A PCR-based platform for microRNA expression profiling studies
    • Wang X. A PCR-based platform for microRNA expression profiling studies. RNA. 2009; 15:716-723.
    • (2009) RNA , vol.15 , pp. 716-723
    • Wang, X.1
  • 45
    • 54249141519 scopus 로고    scopus 로고
    • Endothelial p70 S6 kinase 1 in regulating tumor angiogenesis
    • Liu LZ, Zheng JZ, Wang XR and Jiang BH. Endothelial p70 S6 kinase 1 in regulating tumor angiogenesis. Cancer Res. 2008; 68:8183-8188.
    • (2008) Cancer Res , vol.68 , pp. 8183-8188
    • Liu, L.Z.1    Zheng, J.Z.2    Wang, X.R.3    Jiang, B.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.