-
1
-
-
0035559064
-
Current epidemiological trends and surveillance issues in brain tumors
-
Davis FG, McCarthy BJ. Current epidemiological trends and surveillance issues in brain tumors. Expert Rev Anticancer Ther. 2001;1(3):395-401.
-
(2001)
Expert Rev Anticancer Ther.
, vol.1
, Issue.3
, pp. 395-401
-
-
Davis, F.G.1
McCarthy, B.J.2
-
2
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005;352(10):987-996.
-
(2005)
N Engl J Med.
, vol.352
, Issue.10
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
-
3
-
-
79953052206
-
Inhibition of PI3 K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomide
-
Prasad G, Sottero T, Yang X, et al. Inhibition of PI3 K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomide. Neuro Oncol. 2011;13(4):384-392.
-
(2011)
Neuro Oncol.
, vol.13
, Issue.4
, pp. 384-392
-
-
Prasad, G.1
Sottero, T.2
Yang, X.3
-
4
-
-
84879032241
-
MiR-139 inhibits Mcl-1 expression and potentiates TMZ-induced apoptosis in glioma
-
Li RY, Chen LC, Zhang HY, et al. MiR-139 inhibits Mcl-1 expression and potentiates TMZ-induced apoptosis in glioma. CNS Neurosci Ther. 2013;19(7):477-483.
-
(2013)
CNS Neurosci Ther.
, vol.19
, Issue.7
, pp. 477-483
-
-
Li, R.Y.1
Chen, L.C.2
Zhang, H.Y.3
-
5
-
-
3042767202
-
MicroRNAs: Small RNAs with a big role in gene regulation
-
He L, Hannon GJ. MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet. 2004;5(7):522-531.
-
(2004)
Nat Rev Genet.
, vol.5
, Issue.7
, pp. 522-531
-
-
He, L.1
Hannon, G.J.2
-
6
-
-
84860386287
-
Advances in microRNA experimental approaches to study physiological regulation of gene products implicated in CNS disorders
-
Long JM, Lahiri DK. Advances in microRNA experimental approaches to study physiological regulation of gene products implicated in CNS disorders. Exp Neurol. 2012;235(2):402-418.
-
(2012)
Exp Neurol.
, vol.235
, Issue.2
, pp. 402-418
-
-
Long, J.M.1
Lahiri, D.K.2
-
7
-
-
58249088751
-
MicroRNAs: Target recognition and regulatory functions
-
Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell. 2009;136(2):215-233.
-
(2009)
Cell
, vol.136
, Issue.2
, pp. 215-233
-
-
Bartel, D.P.1
-
8
-
-
84863011293
-
MicroRNA-21 promotes tumor proliferation and invasion in gastric cancer by targeting PTEN
-
Zhang BG, Li JF, Yu BQ, et al. MicroRNA-21 promotes tumor proliferation and invasion in gastric cancer by targeting PTEN. Oncol Rep. 2012;27(4):1019-1026.
-
(2012)
Oncol Rep.
, vol.27
, Issue.4
, pp. 1019-1026
-
-
Zhang, B.G.1
Li, J.F.2
Yu, B.Q.3
-
9
-
-
79961065195
-
The microRNA-21-PDCD4 axis prevents type 1 diabetes by blocking pancreatic beta cell death
-
Ruan Q, Wang T, Kameswaran V, et al. The microRNA-21-PDCD4 axis prevents type 1 diabetes by blocking pancreatic beta cell death. Proc Natl Acad Sci U S A. 2011;108(29):12030-12035.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.29
, pp. 12030-12035
-
-
Ruan, Q.1
Wang, T.2
Kameswaran, V.3
-
10
-
-
84859539080
-
MicroRNA-195 plays a tumor-suppressor role in human glioblastoma cells by targeting signaling pathways involved in cellular proliferation and invasion
-
Zhang QQ, Xu H, Huang MB, et al. MicroRNA-195 plays a tumor-suppressor role in human glioblastoma cells by targeting signaling pathways involved in cellular proliferation and invasion. Neuro Oncol. 2012;14(3):278-287.
-
(2012)
Neuro Oncol.
, vol.14
, Issue.3
, pp. 278-287
-
-
Zhang, Q.Q.1
Xu, H.2
Huang, M.B.3
-
11
-
-
84880737108
-
MicroRNA-124 inhibits migration and invasion by down-regulating ROCK1 in glioma
-
An L, Liu Y, Wu A, Guan Y. MicroRNA-124 inhibits migration and invasion by down-regulating ROCK1 in glioma. PLoS One. 2013;8(7):e69478.
-
(2013)
PLoS One
, vol.8
, Issue.7
, pp. e69478
-
-
An, L.1
Liu, Y.2
Wu, A.3
Guan, Y.4
-
12
-
-
84880062228
-
MiR-124 inhibits STAT3 signaling to enhance T cell-mediated immune clearance of glioma
-
Wei J, Wang F, Kong LY, et al. MiR-124 inhibits STAT3 signaling to enhance T cell-mediated immune clearance of glioma. Cancer Res. 2013;73(13):3913-3926.
-
(2013)
Cancer Res.
, vol.73
, Issue.13
, pp. 3913-3926
-
-
Wei, J.1
Wang, F.2
Kong, L.Y.3
-
14
-
-
8844252330
-
Mutation analysis of the Ras pathway genes NRAS, HRAS, KRAS and BRAF in glioblastomas
-
Knobbe CB, Reifenberger J, Reifenberger G. Mutation analysis of the Ras pathway genes NRAS, HRAS, KRAS and BRAF in glioblastomas. Acta Neuropathol. 2004;108(6):467-470.
-
(2004)
Acta Neuropathol.
, vol.108
, Issue.6
, pp. 467-470
-
-
Knobbe, C.B.1
Reifenberger, J.2
Reifenberger, G.3
-
15
-
-
28644439947
-
R-Ras is a global regulator of vascular regeneration that suppresses intimal hyperplasia and tumor angiogenesis
-
Komatsu M, Ruoslahti E. R-Ras is a global regulator of vascular regeneration that suppresses intimal hyperplasia and tumor angiogenesis. Nat Med. 2005;11(12):1346-1350.
-
(2005)
Nat Med.
, vol.11
, Issue.12
, pp. 1346-1350
-
-
Komatsu, M.1
Ruoslahti, E.2
-
16
-
-
25144492370
-
EphB2/R-Ras signaling regulates glioma cell adhesion, growth, and invasion
-
Nakada M, Niska JA, Tran NL, et al. EphB2/R-Ras signaling regulates glioma cell adhesion, growth, and invasion. Am J Pathol. 2005;167(2):565-576.
-
(2005)
Am J Pathol.
, vol.167
, Issue.2
, pp. 565-576
-
-
Nakada, M.1
Niska, J.A.2
Tran, N.L.3
-
17
-
-
84891846003
-
Overexpressed let-7a inhibits glioma cell malignancy by directly targeting K-ras, independently of PTEN
-
Wang XR, Luo H, Li HL, et al. Overexpressed let-7a inhibits glioma cell malignancy by directly targeting K-ras, independently of PTEN. Neuro Oncol. 2013;15(11):1491-1501.
-
(2013)
Neuro Oncol.
, vol.15
, Issue.11
, pp. 1491-1501
-
-
Wang, X.R.1
Luo, H.2
Li, H.L.3
-
18
-
-
84934438094
-
MicroRNAs in melanoma biology
-
Kunz M. MicroRNAs in melanoma biology. Adv Exp Med Biol. 2013;774:103-120.
-
(2013)
Adv Exp Med Biol.
, vol.774
, pp. 103-120
-
-
Kunz, M.1
-
19
-
-
84874626235
-
MiR148b is a major coordinator of breast cancer progression in a relapse-associated microRNA signature by targeting ITGA5, ROCK1, PIK3CA, NRAS, and CSF1
-
Cimino D, De Pitta C, Orso F, et al. MiR148b is a major coordinator of breast cancer progression in a relapse-associated microRNA signature by targeting ITGA5, ROCK1, PIK3CA, NRAS, and CSF1. FASEB J. 2013;27(3):1223-1235.
-
(2013)
FASEB J.
, vol.27
, Issue.3
, pp. 1223-1235
-
-
Cimino, D.1
De Pitta, C.2
Orso, F.3
-
20
-
-
84877116748
-
MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy
-
Halkein J, Tabruyn SP, Ricke-Hoch M, et al. MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy. J Clin Invest. 2013;123(5):2143-2154.
-
(2013)
J Clin Invest.
, vol.123
, Issue.5
, pp. 2143-2154
-
-
Halkein, J.1
Tabruyn, S.P.2
Ricke-Hoch, M.3
-
21
-
-
84855380396
-
MicroRNA-622 functions as a tumor suppressor by targeting K-Ras and enhancing the anticarcinogenic effect of resveratrol
-
Han Z, Yang Q, Liu B, et al. MicroRNA-622 functions as a tumor suppressor by targeting K-Ras and enhancing the anticarcinogenic effect of resveratrol. Carcinogenesis. 2012;33(1):131-139.
-
(2012)
Carcinogenesis
, vol.33
, Issue.1
, pp. 131-139
-
-
Han, Z.1
Yang, Q.2
Liu, B.3
-
22
-
-
33947594129
-
Hyperactive Ras in developmental disorders and cancer
-
Schubbert S, Shannon K, Bollag G. Hyperactive Ras in developmental disorders and cancer. Nat Rev Cancer. 2007;7(4):295-308.
-
(2007)
Nat Rev Cancer
, vol.7
, Issue.4
, pp. 295-308
-
-
Schubbert, S.1
Shannon, K.2
Bollag, G.3
-
23
-
-
34547942530
-
Targeting oncogenic Ras
-
Diaz-Flores E, Shannon K. Targeting oncogenic Ras. Genes Dev. 2007;21(16):1989-1992.
-
(2007)
Genes Dev.
, vol.21
, Issue.16
, pp. 1989-1992
-
-
Diaz-Flores, E.1
Shannon, K.2
-
24
-
-
0042734450
-
Oxidized phospholipid-induced endothelial cell/monocyte interaction is mediated by a cAMP-dependent R-Ras/PI3-kinase pathway
-
Cole AL, Subbanagounder G, Mukhopadhyay S, et al. Oxidized phospholipid-induced endothelial cell/monocyte interaction is mediated by a cAMP-dependent R-Ras/PI3-kinase pathway. Arterioscler Thromb Vasc Biol. 2003;23(8):1384-1390.
-
(2003)
Arterioscler Thromb Vasc Biol.
, vol.23
, Issue.8
, pp. 1384-1390
-
-
Cole, A.L.1
Subbanagounder, G.2
Mukhopadhyay, S.3
-
25
-
-
77954022714
-
Genetic alterations in the RAS/RAF/mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways in the follicular variant of papillary thyroid carcinoma
-
Santarpia L, Myers JN, Sherman SI, et al. Genetic alterations in the RAS/RAF/mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways in the follicular variant of papillary thyroid carcinoma. Cancer. 2010;116(12):2974-2983.
-
(2010)
Cancer
, vol.116
, Issue.12
, pp. 2974-2983
-
-
Santarpia, L.1
Myers, J.N.2
Sherman, S.I.3
-
26
-
-
84874613332
-
Combined targeting of MEK and PI3 K/mTOR effector pathways is necessary to effectively inhibit NRAS mutant melanoma in vitro and in vivo
-
Posch C, Moslehi H, Feeney L, et al. Combined targeting of MEK and PI3 K/mTOR effector pathways is necessary to effectively inhibit NRAS mutant melanoma in vitro and in vivo. Proc Natl Acad Sci U S A. 2013;110(10):4015-4020.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, Issue.10
, pp. 4015-4020
-
-
Posch, C.1
Moslehi, H.2
Feeney, L.3
-
27
-
-
29144470346
-
Real-time quantification of microRNAs by stem-loop RT-PCR
-
Chen C, Ridzon DA, Broomer AJ, et al. Real-time quantification of microRNAs by stem-loop RT-PCR. Nucleic Acids Res. 2005;33(20):e179.
-
(2005)
Nucleic Acids Res.
, vol.33
, Issue.20
, pp. e179
-
-
Chen, C.1
Ridzon, D.A.2
Broomer, A.J.3
-
28
-
-
62549130754
-
A PCR-based platform for microRNA expression profiling studies
-
Wang X. A PCR-based platform for microRNA expression profiling studies. RNA. 2009;15(4):716-723.
-
(2009)
RNA
, vol.15
, Issue.4
, pp. 716-723
-
-
Wang, X.1
-
29
-
-
84865151156
-
Small GTPase R-Ras regulates integrity and functionality of tumor blood vessels
-
Sawada J, Urakami T, Li F, et al. Small GTPase R-Ras regulates integrity and functionality of tumor blood vessels. Cancer Cell. 2012;22(2):235-249.
-
(2012)
Cancer Cell
, vol.22
, Issue.2
, pp. 235-249
-
-
Sawada, J.1
Urakami, T.2
Li, F.3
-
30
-
-
84867084482
-
The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling
-
Sandri C, Caccavari F, Valdembri D, et al. The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling. Cell Res. 2012;22(10):1479-1501.
-
(2012)
Cell Res.
, vol.22
, Issue.10
, pp. 1479-1501
-
-
Sandri, C.1
Caccavari, F.2
Valdembri, D.3
-
31
-
-
84877847218
-
Oncogenic NRAS, required for pathogenesis of embryonic rhabdomyosarcoma, relies upon the HMGA2-IGF2BP2 pathway
-
Li Z, Zhang Y, Ramanujan K, et al. Oncogenic NRAS, required for pathogenesis of embryonic rhabdomyosarcoma, relies upon the HMGA2-IGF2BP2 pathway. Cancer Res. 2013;73(10):3041-3050.
-
(2013)
Cancer Res.
, vol.73
, Issue.10
, pp. 3041-3050
-
-
Li, Z.1
Zhang, Y.2
Ramanujan, K.3
-
32
-
-
84877097856
-
Characteristics of lung cancers harboring NRAS mutations
-
Ohashi K, Sequist LV, Arcila ME, et al. Characteristics of lung cancers harboring NRAS mutations. Clin Cancer Res. 2013;19(9):2584-2591.
-
(2013)
Clin Cancer Res.
, vol.19
, Issue.9
, pp. 2584-2591
-
-
Ohashi, K.1
Sequist, L.V.2
Arcila, M.E.3
-
33
-
-
84879771957
-
Functional crosstalk between Akt/mTOR and Ras/MAPK pathways in hepatocarcinogenesis: Implications for the treatment of human liver cancer
-
Wang C, Cigliano A, Delogu S, et al. Functional crosstalk between Akt/mTOR and Ras/MAPK pathways in hepatocarcinogenesis: implications for the treatment of human liver cancer. Cell Cycle. 2013;12(13):1999-2010.
-
(2013)
Cell Cycle
, vol.12
, Issue.13
, pp. 1999-2010
-
-
Wang, C.1
Cigliano, A.2
Delogu, S.3
-
34
-
-
79959712087
-
Ras/Raf/MEK/ERK and PI3 K/PTEN/Akt/mTOR inhibitors: Rationale and importance to inhibiting these pathways in human health
-
ChappellWH, Steelman LS, Long JM, et al. Ras/Raf/MEK/ERK and PI3 K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health. Oncotarget. 2011;2(3):135-164.
-
(2011)
Oncotarget
, vol.2
, Issue.3
, pp. 135-164
-
-
Chappell, W.H.1
Steelman, L.S.2
Long, J.M.3
-
35
-
-
22544463087
-
Integrating signals between cAMP and the RAS/RAF/MEK/ERK signalling pathways. Based on the anniversary prize of the Gesellschaft fur Biochemie und Molekularbiologie Lecture delivered on 5 July 2003 at the Special FEBS Meeting in Brussels
-
Dumaz N, Marais R. Integrating signals between cAMP and the RAS/RAF/MEK/ERK signalling pathways. Based on the anniversary prize of the Gesellschaft fur Biochemie und Molekularbiologie Lecture delivered on 5 July 2003 at the Special FEBS Meeting in Brussels. FEBS J. 2005;272(14):3491-3504.
-
(2005)
FEBS J.
, vol.272
, Issue.14
, pp. 3491-3504
-
-
Dumaz, N.1
Marais, R.2
-
36
-
-
21344456180
-
The RAS/RAF/MEK/ERK and PI3 K/AKT signaling pathways present molecular targets for the effective treatment of advanced melanoma
-
Meier F, Schittek B, Busch S, et al. The RAS/RAF/MEK/ERK and PI3 K/AKT signaling pathways present molecular targets for the effective treatment of advanced melanoma. Front Biosci. 2005;10:2986-3001.
-
(2005)
Front Biosci.
, vol.10
, pp. 2986-3001
-
-
Meier, F.1
Schittek, B.2
Busch, S.3
-
37
-
-
34047132303
-
Apigenin inhibits tumor angiogenesis through decreasing HIF-1alpha and VEGF expression
-
Fang J, Zhou Q, Liu LZ, et al. Apigenin inhibits tumor angiogenesis through decreasing HIF-1alpha and VEGF expression. Carcinogenesis. 2007;28(4):858-864.
-
(2007)
Carcinogenesis
, vol.28
, Issue.4
, pp. 858-864
-
-
Fang, J.1
Zhou, Q.2
Liu, L.Z.3
-
38
-
-
0036984640
-
Role of angiogenesis in tumor growth and metastasis
-
Folkman J. Role of angiogenesis in tumor growth and metastasis. Semin Oncol. 2002;29(Suppl 616):15-18.
-
(2002)
Semin Oncol.
, vol.29
, pp. 15-18
-
-
Folkman, J.1
-
39
-
-
79953792348
-
Fyn is induced by Ras/PI3 K/Akt signaling and is required for enhanced invasion/migration
-
Yadav V, Denning MF. Fyn is induced by Ras/PI3 K/Akt signaling and is required for enhanced invasion/migration. Mol Carcinog. 2011;50(5):346-352.
-
(2011)
Mol Carcinog
, vol.50
, Issue.5
, pp. 346-352
-
-
Yadav, V.1
Denning, M.F.2
-
40
-
-
11244270824
-
Thymosin {beta} (10) inhibits angiogenesis and tumor growth by interfering with Ras function
-
Lee SH, Son MJ, Oh SH, et al. Thymosin {beta} (10) inhibits angiogenesis and tumor growth by interfering with Ras function. Cancer Res. 2005;65(1):137-148.
-
(2005)
Cancer Res.
, vol.65
, Issue.1
, pp. 137-148
-
-
Lee, S.H.1
Son, M.J.2
Oh, S.H.3
-
41
-
-
13944282215
-
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
-
Lim LP, Lau NC, Garrett-Engele P, et al. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature. 2005;433(7027):769-773.
-
(2005)
Nature
, vol.433
, Issue.7027
, pp. 769-773
-
-
Lim, L.P.1
Lau, N.C.2
Garrett-Engele, P.3
-
42
-
-
84872494254
-
A systematic review of microRNA in glioblastoma multiforme: Micro-modulators in the mesenchymal mode of migration and invasion
-
Moller HG, Rasmussen AP, Andersen HH, et al. A systematic review of microRNA in glioblastoma multiforme: micro-modulators in the mesenchymal mode of migration and invasion. Mol Neurobiol. 2013;47(1):131-144.
-
(2013)
Mol Neurobiol.
, vol.47
, Issue.1
, pp. 131-144
-
-
Moller, H.G.1
Rasmussen, A.P.2
Andersen, H.H.3
-
43
-
-
13444283313
-
Ras inhibition in glioblastoma down-regulates hypoxia-inducible factor-1alpha, causing glycolysis shutdown and cell death
-
Blum R, Jacob-Hirsch J, Amariglio N, et al. Ras inhibition in glioblastoma down-regulates hypoxia-inducible factor-1alpha, causing glycolysis shutdown and cell death. Cancer Res. 2005;65(3):999-1006.
-
(2005)
Cancer Res.
, vol.65
, Issue.3
, pp. 999-1006
-
-
Blum, R.1
Jacob-Hirsch, J.2
Amariglio, N.3
-
44
-
-
84861861100
-
MiR-145 inhibits tumor angiogenesis and growth by N-RAS and VEGF
-
Zou C, Xu Q, Mao F, et al. MiR-145 inhibits tumor angiogenesis and growth by N-RAS and VEGF. Cell Cycle. 2012;11(11):2137-2145.
-
(2012)
Cell Cycle
, vol.11
, Issue.11
, pp. 2137-2145
-
-
Zou, C.1
Xu, Q.2
Mao, F.3
-
45
-
-
77955297403
-
R-Ras regulates migration through an interaction with filamin A in melanoma cells
-
Gawecka JE, Griffiths GS, Ek-Rylander B, et al. R-Ras regulates migration through an interaction with filamin A in melanoma cells. PLoS One. 2010;5(6):e11269.
-
(2010)
PLoS One
, vol.5
, Issue.6
, pp. e11269
-
-
Gawecka, J.E.1
Griffiths, G.S.2
Ek-Rylander, B.3
-
46
-
-
20044395613
-
RAS is regulated by the let-7 microRNA family
-
Johnson SM, Grosshans H, Shingara J, et al. RAS is regulated by the let-7 microRNA family. Cell. 2005;120(5):635-647.
-
(2005)
Cell
, vol.120
, Issue.5
, pp. 635-647
-
-
Johnson, S.M.1
Grosshans, H.2
Shingara, J.3
-
47
-
-
84860448293
-
Genome-wide profiling identified a set of miRNAs that are differentially expressed in glioblastoma stem cells and normal neural stem cells
-
Lang MF, Yang S, Zhao C, et al. Genome-wide profiling identified a set of miRNAs that are differentially expressed in glioblastoma stem cells and normal neural stem cells. PLoS One. 2012;7(4):e36248.
-
(2012)
PLoS One
, vol.7
, Issue.4
, pp. e36248
-
-
Lang, M.F.1
Yang, S.2
Zhao, C.3
|