-
1
-
-
84861227000
-
The mystery of C. elegans aging: an emerging role for fat: distant parallels between C. elegans aging and metabolic syndrome?
-
Ackerman D, Gems D (2012) The mystery of C. elegans aging: an emerging role for fat: distant parallels between C. elegans aging and metabolic syndrome? BioEssays 34, 466.
-
(2012)
BioEssays
, vol.34
, pp. 466
-
-
Ackerman, D.1
Gems, D.2
-
2
-
-
33947387075
-
On the evolutionary origin of aging
-
Ackermann M, Chao L, Bergstrom CT, Doebeli M (2007) On the evolutionary origin of aging. Aging Cell 6, 235–244.
-
(2007)
Aging Cell
, vol.6
, pp. 235-244
-
-
Ackermann, M.1
Chao, L.2
Bergstrom, C.T.3
Doebeli, M.4
-
3
-
-
84899837861
-
Age- and diet-associated metabolome remodeling characterizes the aging process driven by damage accumulation
-
Avanesov AS, Ma S, Pierce KA, Yim SH, Lee BC, Clish CB, Gladyshev VN (2014) Age- and diet-associated metabolome remodeling characterizes the aging process driven by damage accumulation. eLife 3, e02077.
-
(2014)
eLife
, vol.3
-
-
Avanesov, A.S.1
Ma, S.2
Pierce, K.A.3
Yim, S.H.4
Lee, B.C.5
Clish, C.B.6
Gladyshev, V.N.7
-
4
-
-
55849152355
-
Aging: ROS or TOR
-
Blagosklonny MV (2008) Aging: ROS or TOR. Cell Cycle 7, 3344.
-
(2008)
Cell Cycle
, vol.7
, pp. 3344
-
-
Blagosklonny, M.V.1
-
5
-
-
47549100826
-
An elt-3/elt-5/elt-6 GATA transcription circuit guides aging in C. elegans
-
Budovskaya YV, Wu K, Southworth LK, Jiang M, Tedesco P, Johnson TE, Kim SK (2008) An elt-3/elt-5/elt-6 GATA transcription circuit guides aging in C. elegans. Cell 134, 291–303.
-
(2008)
Cell
, vol.134
, pp. 291-303
-
-
Budovskaya, Y.V.1
Wu, K.2
Southworth, L.K.3
Jiang, M.4
Tedesco, P.5
Johnson, T.E.6
Kim, S.K.7
-
7
-
-
84885223714
-
Fission yeast does not age under favorable conditions, but does so after stress
-
Coelho M, Dereli A, Haese A, Kühn S, Malinovska L, DeSantis ME, Shorter J, Alberti S, Gross T, Tolić-Nørrelykke IM (2013) Fission yeast does not age under favorable conditions, but does so after stress. Curr. Biol. 23, 1844–1852.
-
(2013)
Curr. Biol.
, vol.23
, pp. 1844-1852
-
-
Coelho, M.1
Dereli, A.2
Haese, A.3
Kühn, S.4
Malinovska, L.5
DeSantis, M.E.6
Shorter, J.7
Alberti, S.8
Gross, T.9
Tolić-Nørrelykke, I.M.10
-
8
-
-
34247575680
-
Damage segregation at fissioning may increase growth rates: a superprocess model
-
Evans SN, Steinsaltz D (2007) Damage segregation at fissioning may increase growth rates: a superprocess model. Theor. Popul. Biol. 71, 473–490.
-
(2007)
Theor. Popul. Biol.
, vol.71
, pp. 473-490
-
-
Evans, S.N.1
Steinsaltz, D.2
-
9
-
-
84922541951
-
Adaptations to a subterranean environment and longevity revealed by the analysis of mole rat genomes
-
Fang X, Seim I, Huang Z, Gerashchenko MV, Xiong Z, Turanov AA, Zhu Y, Lobanov AV, Fan D, Yim SH, Yao X, Ma S, Yang L, Lee SG, Kim EB, Bronson RT, Sumbera R, Buffenstein R, Zhou X, Krogh A, Park TJ, Zhang G, Wang J, Gladyshev VN (2014) Adaptations to a subterranean environment and longevity revealed by the analysis of mole rat genomes. Cell Rep. 8, 1354–1364.
-
(2014)
Cell Rep.
, vol.8
, pp. 1354-1364
-
-
Fang, X.1
Seim, I.2
Huang, Z.3
Gerashchenko, M.V.4
Xiong, Z.5
Turanov, A.A.6
Zhu, Y.7
Lobanov, A.V.8
Fan, D.9
Yim, S.H.10
Yao, X.11
Ma, S.12
Yang, L.13
Lee, S.G.14
Kim, E.B.15
Bronson, R.T.16
Sumbera, R.17
Buffenstein, R.18
Zhou, X.19
Krogh, A.20
Park, T.J.21
Zhang, G.22
Wang, J.23
Gladyshev, V.N.24
more..
-
11
-
-
84927910038
-
Gene expression defines natural changes in mammalian lifespan
-
Fushan AA, Turanov AA, Lee SG, Kim EB, Lobanov AV, Yim SH, Buffenstein R, Lee SR, Chang KT, Rhee H, Kim JS, Yang KS, Gladyshev VN (2015) Gene expression defines natural changes in mammalian lifespan. Aging Cell 14, 352–365.
-
(2015)
Aging Cell
, vol.14
, pp. 352-365
-
-
Fushan, A.A.1
Turanov, A.A.2
Lee, S.G.3
Kim, E.B.4
Lobanov, A.V.5
Yim, S.H.6
Buffenstein, R.7
Lee, S.R.8
Chang, K.T.9
Rhee, H.10
Kim, J.S.11
Yang, K.S.12
Gladyshev, V.N.13
-
12
-
-
0035930837
-
The reliability theory of aging and longevity
-
Gavrilov LA, Gavrilova NS (2001) The reliability theory of aging and longevity. J. Theor. Biol. 213, 527–545.
-
(2001)
J. Theor. Biol.
, vol.213
, pp. 527-545
-
-
Gavrilov, L.A.1
Gavrilova, N.S.2
-
13
-
-
84867435039
-
On the cause of aging and control of lifespan: heterogeneity leads to inevitable damage accumulation, causing aging; control of damage composition and rate of accumulation define lifespan
-
Gladyshev VN (2012) On the cause of aging and control of lifespan: heterogeneity leads to inevitable damage accumulation, causing aging; control of damage composition and rate of accumulation define lifespan. BioEssays 34, 925.
-
(2012)
BioEssays
, vol.34
, pp. 925
-
-
Gladyshev, V.N.1
-
14
-
-
84882603593
-
The origin of aging: imperfectness-driven non-random damage defines the aging process and control of lifespan
-
Gladyshev VN (2013) The origin of aging: imperfectness-driven non-random damage defines the aging process and control of lifespan. Trends Genet. 29, 506–512.
-
(2013)
Trends Genet.
, vol.29
, pp. 506-512
-
-
Gladyshev, V.N.1
-
15
-
-
84892915705
-
The free radical theory of aging is dead. Long live the damage theory!
-
Gladyshev VN (2014) The free radical theory of aging is dead. Long live the damage theory!. Antioxid. Redox Signal. 20, 727–731.
-
(2014)
Antioxid. Redox Signal.
, vol.20
, pp. 727-731
-
-
Gladyshev, V.N.1
-
16
-
-
0030277436
-
The other side of metabolism
-
Golubev AG (1996) The other side of metabolism. Biokhimiia 61, 2018–2039.
-
(1996)
Biokhimiia
, vol.61
, pp. 2018-2039
-
-
Golubev, A.G.1
-
18
-
-
0013942563
-
The moulding of senescence by natural selection
-
Hamilton WD (1966) The moulding of senescence by natural selection. J. Theor. Biol. 12, 12–45.
-
(1966)
J. Theor. Biol.
, vol.12
, pp. 12-45
-
-
Hamilton, W.D.1
-
19
-
-
84872806231
-
Genome-wide methylation profiles reveal quantitative views of human aging rates
-
Hannum G, Guinney J, Zhao L, Zhang L, Hughes G, Sadda S, Klotzle B, Bibikova M, Fan JB, Gao Y, Deconde R, Chen M, Rajapakse I, Friend S, Ideker T, Zhang K (2013) Genome-wide methylation profiles reveal quantitative views of human aging rates. Mol. Cell 49, 359–367.
-
(2013)
Mol. Cell
, vol.49
, pp. 359-367
-
-
Hannum, G.1
Guinney, J.2
Zhao, L.3
Zhang, L.4
Hughes, G.5
Sadda, S.6
Klotzle, B.7
Bibikova, M.8
Fan, J.B.9
Gao, Y.10
Deconde, R.11
Chen, M.12
Rajapakse, I.13
Friend, S.14
Ideker, T.15
Zhang, K.16
-
20
-
-
77049308856
-
Aging: a theory based on free radical and radiation chemistry
-
Harman D (1956) Aging: a theory based on free radical and radiation chemistry. J. Gerontol. 11, 298.
-
(1956)
J. Gerontol.
, vol.11
, pp. 298
-
-
Harman, D.1
-
21
-
-
84905005772
-
Effects of age, sex, and genotype on high-sensitivity metabolomic profiles in the fruit fly, Drosophila melanogaster
-
Hoffman JM, Soltow QA, Li S, Sidik A, Jones DP, Promislow DE (2014) Effects of age, sex, and genotype on high-sensitivity metabolomic profiles in the fruit fly, Drosophila melanogaster. Aging Cell 13, 596–604.
-
(2014)
Aging Cell
, vol.13
, pp. 596-604
-
-
Hoffman, J.M.1
Soltow, Q.A.2
Li, S.3
Sidik, A.4
Jones, D.P.5
Promislow, D.E.6
-
22
-
-
84886111619
-
DNA methylation age of human tissues and cell types
-
Horvath S (2013) DNA methylation age of human tissues and cell types. Genome Biol. 14, R115.
-
(2013)
Genome Biol.
, vol.14
, pp. R115
-
-
Horvath, S.1
-
23
-
-
84892367491
-
Diversity of ageing across the tree of life
-
Jones OR, Scheuerlein A, Salguero-Gómez R, Camarda CG, Schaible R, Casper BB, Dahlgren JP, Ehrlén J, García MB, Menges ES, Quintana-Ascencio PF, Caswell H, Baudisch A, Vaupel JW (2014) Diversity of ageing across the tree of life. Nature 505, 169–173.
-
(2014)
Nature
, vol.505
, pp. 169-173
-
-
Jones, O.R.1
Scheuerlein, A.2
Salguero-Gómez, R.3
Camarda, C.G.4
Schaible, R.5
Casper, B.B.6
Dahlgren, J.P.7
Ehrlén, J.8
García, M.B.9
Menges, E.S.10
Quintana-Ascencio, P.F.11
Caswell, H.12
Baudisch, A.13
Vaupel, J.W.14
-
24
-
-
84927913417
-
Evidence that mutation accumulation does not cause aging in Sacharomyces cerevisiae
-
Kaya A, Lobanov AV, Gladyshev VN (2015) Evidence that mutation accumulation does not cause aging in Sacharomyces cerevisiae. Aging Cell 14, 366–371.
-
(2015)
Aging Cell
, vol.14
, pp. 366-371
-
-
Kaya, A.1
Lobanov, A.V.2
Gladyshev, V.N.3
-
25
-
-
0017782437
-
Evolution of ageing
-
Kirkwood TB (1977) Evolution of ageing. Nature 270, 301.
-
(1977)
Nature
, vol.270
, pp. 301
-
-
Kirkwood, T.B.1
-
27
-
-
80051801494
-
-
Upper Saddle River, NJ, FT Press Science
-
Koonin EV (2011) The Logic of Chance. Upper Saddle River, NJ: FT Press Science.
-
(2011)
The Logic of Chance
-
-
Koonin, E.V.1
-
28
-
-
85006309703
-
Early life expenditure in sexual competition is associated with increased reproductive senescence in male red deer
-
Lemaître JF, Gaillard JM, Pemberton JM, Clutton-Brock TH, Nussey DH (2014) Early life expenditure in sexual competition is associated with increased reproductive senescence in male red deer. Proc. Biol. Sci. 281, 1792.
-
(2014)
Proc. Biol. Sci.
, vol.281
, pp. 1792
-
-
Lemaître, J.F.1
Gaillard, J.M.2
Pemberton, J.M.3
Clutton-Brock, T.H.4
Nussey, D.H.5
-
30
-
-
84878864199
-
The hallmarks of aging
-
López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G (2013) The hallmarks of aging. Cell 153, 1194–1217.
-
(2013)
Cell
, vol.153
, pp. 1194-1217
-
-
López-Otín, C.1
Blasco, M.A.2
Partridge, L.3
Serrano, M.4
Kroemer, G.5
-
31
-
-
84938594839
-
Organization of the mammalian metabolome according to organ function, lineage specialization, and longevity
-
Ma S, Yim SH, Lee SG, Kim EB, Lee SR, Chang KT, Buffenstein R, Lewis KN, Park TJ, Miller RA, Clish CB, Gladyshev VN (2015) Organization of the mammalian metabolome according to organ function, lineage specialization, and longevity. Cell Metab. 22, 332–343.
-
(2015)
Cell Metab.
, vol.22
, pp. 332-343
-
-
Ma, S.1
Yim, S.H.2
Lee, S.G.3
Kim, E.B.4
Lee, S.R.5
Chang, K.T.6
Buffenstein, R.7
Lewis, K.N.8
Park, T.J.9
Miller, R.A.10
Clish, C.B.11
Gladyshev, V.N.12
-
32
-
-
84870348799
-
Programmatic features of aging originating in development: aging mechanisms beyond molecular damage?
-
de Magalhaes JP (2012) Programmatic features of aging originating in development: aging mechanisms beyond molecular damage? FASEB J. 26, 4821.
-
(2012)
FASEB J.
, vol.26
, pp. 4821
-
-
de Magalhaes, J.P.1
-
34
-
-
55749090979
-
A theory of age-dependent mutation and senescence
-
Moorad JA, Promislow DE (2008) A theory of age-dependent mutation and senescence. Genetics 179, 2061–2073.
-
(2008)
Genetics
, vol.179
, pp. 2061-2073
-
-
Moorad, J.A.1
Promislow, D.E.2
-
35
-
-
39449084386
-
Use of stable isotopes to examine how dietary restriction extends Drosophila lifespan
-
O'Brien DM, Min KJ, Larsen T, Tatar M (2008) Use of stable isotopes to examine how dietary restriction extends Drosophila lifespan. Curr. Biol. 18, R155–R156.
-
(2008)
Curr. Biol.
, vol.18
, pp. R155-R156
-
-
O'Brien, D.M.1
Min, K.J.2
Larsen, T.3
Tatar, M.4
-
36
-
-
0015932795
-
Ageing of clones of mammalian cells
-
Orgel LE (1973) Ageing of clones of mammalian cells. Nature 243, 441.
-
(1973)
Nature
, vol.243
, pp. 441
-
-
Orgel, L.E.1
-
38
-
-
84883142476
-
Genome analysis reveals insights into physiology and longevity of the Brandt's bat Myotis brandtii
-
Seim I, Fang X, Xiong Z, Lobanov AV, Huang Z, Ma S, Feng Y, Turanov AA, Zhu Y, Lenz TL, Gerashchenko MV, Fan D, Yim SH, Yao X, Jordan D, Xiong Y, Ma Y, Lyapunov AN, Chen G, Kulakova OI, Sun Y, Lee SG, Bronson RT, Moskalev AA, Sunyaev SR, Zhang G, Krogh A, Wang J, Gladyshev VN (2013) Genome analysis reveals insights into physiology and longevity of the Brandt's bat Myotis brandtii. Nat. Commun. 4, 2212.
-
(2013)
Nat. Commun.
, vol.4
, pp. 2212
-
-
Seim, I.1
Fang, X.2
Xiong, Z.3
Lobanov, A.V.4
Huang, Z.5
Ma, S.6
Feng, Y.7
Turanov, A.A.8
Zhu, Y.9
Lenz, T.L.10
Gerashchenko, M.V.11
Fan, D.12
Yim, S.H.13
Yao, X.14
Jordan, D.15
Xiong, Y.16
Ma, Y.17
Lyapunov, A.N.18
Chen, G.19
Kulakova, O.I.20
Sun, Y.21
Lee, S.G.22
Bronson, R.T.23
Moskalev, A.A.24
Sunyaev, S.R.25
Zhang, G.26
Krogh, A.27
Wang, J.28
Gladyshev, V.N.29
more..
-
39
-
-
0031459980
-
Extrachromosomal rDNA circles–a cause of aging in yeast
-
Sinclair DA, Guarente L (1997) Extrachromosomal rDNA circles–a cause of aging in yeast. Cell 91, 1033–1042.
-
(1997)
Cell
, vol.91
, pp. 1033-1042
-
-
Sinclair, D.A.1
Guarente, L.2
-
40
-
-
0031266238
-
Aging is a specific biological function rather than the result of a disorder in complex living systems: biochemical evidence in support of Weismann's hypothesis
-
Skulachev VP (1997) Aging is a specific biological function rather than the result of a disorder in complex living systems: biochemical evidence in support of Weismann's hypothesis. Biochemistry (Mosc) 62, 1191–1195.
-
(1997)
Biochemistry (Mosc)
, vol.62
, pp. 1191-1195
-
-
Skulachev, V.P.1
-
41
-
-
77956275374
-
MicroRNA, mRNA, and protein expression link development and aging in human and macaque brain
-
Somel M, Guo S, Fu N, Yan Z, Hu HY, Xu Y, Yuan Y, Ning Z, Hu Y, Menzel C, Hu H, Lachmann M, Zeng R, Chen W, Khaitovich P (2010) MicroRNA, mRNA, and protein expression link development and aging in human and macaque brain. Genome Res. 20, 1207–1218.
-
(2010)
Genome Res.
, vol.20
, pp. 1207-1218
-
-
Somel, M.1
Guo, S.2
Fu, N.3
Yan, Z.4
Hu, H.Y.5
Xu, Y.6
Yuan, Y.7
Ning, Z.8
Hu, Y.9
Menzel, C.10
Hu, H.11
Lachmann, M.12
Zeng, R.13
Chen, W.14
Khaitovich, P.15
-
43
-
-
50649101095
-
Puzzles, promises and a cure for ageing
-
Vijg J, Campisi J (2008) Puzzles, promises and a cure for ageing. Nature 454, 1065.
-
(2008)
Nature
, vol.454
, pp. 1065
-
-
Vijg, J.1
Campisi, J.2
-
44
-
-
33749533976
-
Aging may be a conditional strategic choice and not an inevitable outcome for bacteria
-
Watve M, Parab S, Jogdand P, Keni S (2006) Aging may be a conditional strategic choice and not an inevitable outcome for bacteria. Proc. Natl Acad. Sci. USA 103, 14831–14835.
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 14831-14835
-
-
Watve, M.1
Parab, S.2
Jogdand, P.3
Keni, S.4
-
45
-
-
84896725382
-
No senescence despite declining selection pressure: Hamilton's result in broader perspective
-
Wensink MJ, Wrycza TF, Baudisch A (2014) No senescence despite declining selection pressure: Hamilton's result in broader perspective. J. Theor. Biol. 347, 176–181.
-
(2014)
J. Theor. Biol.
, vol.347
, pp. 176-181
-
-
Wensink, M.J.1
Wrycza, T.F.2
Baudisch, A.3
-
46
-
-
0000055057
-
Pleiotropy, natural selection, and the evolution of senescence
-
Williams GC (1957) Pleiotropy, natural selection, and the evolution of senescence. Evolution 11, 398.
-
(1957)
Evolution
, vol.11
, pp. 398
-
-
Williams, G.C.1
-
47
-
-
84973429949
-
The essential mechanisms of aging: what have we learnt in ten years?
-
Yin D (2016) The essential mechanisms of aging: what have we learnt in ten years? Curr. Top. Med. Chem. 16, 503–510.
-
(2016)
Curr. Top. Med. Chem.
, vol.16
, pp. 503-510
-
-
Yin, D.1
|